Title: The Best 5 Star Hotels in Barnstable, MA from $149 | Expedia.com [Barnstable Travel Guide](https://expedia.com/Barnstable.dx9658)[Hotels in Barnstable](https://expedia.com/Barnstable-Hotels.d9658.Travel-Guide-Hotels)[Vacation Rentals in Barnstable](https://expedia.com/Barnstable-Vacation-Rentals.d9658.Travel-Guide-VacationRentals)[Flights to Barnstable](https://expedia.com/Cheap-Flights-To-Barnstable.d9658.Travel-Guide-Flights)[Things to do in Barnstable](https://expedia.com/Things-To-Do-In-Barnstable.d9658.Travel-Guide-Activities)[Car Rentals in Barnstable](https://expedia.com/Car-Rentals-In-Barnstable.d9658.Car-Rental-Guide)[Barnstable Vacation Packages](https://expedia.com/Barnstable.d9658.Destination-Travel-Guides) ![Barnstable featuring an administrative buidling](https://images.trvl-media.com/place/9658/a910463a-b0d0-4b35-9d10-67783050d4b0.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/9658/a910463a-b0d0-4b35-9d10-67783050d4b0.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Upfront pricing Our total price for your stay includes taxes and fees - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save 10% or more on over 100,000 hotels worldwide with Member Prices [Learn about One Key](https://www.expedia.com/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Barnstable 5 Star Hotels Tonight [Feb 6 - Feb 7](https://www.expedia.com/Hotel-Search?regionId=9658&startDate=2026-02-06&endDate=2026-02-07&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Feb 7 - Feb 8](https://www.expedia.com/Hotel-Search?regionId=9658&startDate=2026-02-07&endDate=2026-02-08&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Feb 6 - Feb 8](https://www.expedia.com/Hotel-Search?regionId=9658&startDate=2026-02-06&endDate=2026-02-08&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Feb 13 - Feb 15](https://www.expedia.com/Hotel-Search?regionId=9658&startDate=2026-02-13&endDate=2026-02-15&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Barnstable 5-star hotels ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/19200/19139/13fe4b58.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/20000/19200/19139/w5700h3895x0y5-016d240d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/19200/19139/efc614b4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/19200/19139/c3fa2de8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Chatham Bars Inn [](https://www.expedia.com/Chatham-Hotels-Chatham-Bars-Inn.h19139.Hotel-Information) Chatham 9.2/10 Wonderful (809 reviews) "Beautiful property " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Eric $364 nightly $417 total Feb 11 - Feb 12 Total with taxes and fees [](https://www.expedia.com/Chatham-Hotels-Chatham-Bars-Inn.h19139.Hotel-Information) ![Round Cove Suite | Frette Italian sheets, premium bedding, down comforters, minibar](https://images.trvl-media.com/lodging/1000000/10000/3700/3689/ce420299.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Frette Italian sheets, premium bedding, down comforters, minibar](https://images.trvl-media.com/lodging/1000000/10000/3700/3689/2c23c623.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/3700/3689/bf11cab5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Junior Room, 1 King Bed | Frette Italian sheets, premium bedding, down comforters, minibar](https://images.trvl-media.com/lodging/1000000/10000/3700/3689/58f6c718.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Wequassett Resort and Golf Club [](https://www.expedia.com/Harwich-Hotels-Wequassett-Resort-And-Golf-Club.h3689.Hotel-Information) Harwich 9.4/10 Exceptional (244 reviews) "The staff is amazing, they are kind and always looking for ways to help and make you feel welcome." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Karla $328 nightly $375 total Feb 19 - Feb 20 Total with taxes and fees [](https://www.expedia.com/Harwich-Hotels-Wequassett-Resort-And-Golf-Club.h3689.Hotel-Information) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.com/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2F5Star-Barnstable-Hotels.s50-0-d9658.Travel-Guide-Filter-Hotels)[ Sign up, it's free ](https://expedia.com/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2F5Star-Barnstable-Hotels.s50-0-d9658.Travel-Guide-Filter-Hotels) ## Explore similar 4-star hotels Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Barnstable. ![Margaritaville Resort Cape Cod](https://images.trvl-media.com/lodging/1000000/20000/12900/12897/b57e0b1f_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Margaritaville Resort Cape Cod 1225 Iyannough Rd Hyannis MA $208 nightly $238 total Feb 10 - Feb 11 Total with taxes and fees 8.6/10 Excellent! (441 reviews) [](https://expedia.com/Hyannis-Hotels-Cape-Codder-Resort-And-Spa.h12897.Hotel-Information) ![Chatham Wayside Inn](https://images.trvl-media.com/lodging/2000000/1520000/1517300/1517204/1adc0002_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Chatham Wayside Inn 512 Main St Chatham MA $172 nightly $197 total Feb 22 - Feb 23 Total with taxes and fees 9.2/10 Wonderful! (629 reviews) [](https://expedia.com/Chatham-Hotels-Chatham-Wayside-Inn.h1517204.Hotel-Information) ![Doubletree by Hilton Cape Cod - Hyannis](https://images.trvl-media.com/lodging/1000000/50000/40500/40461/9f940314_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Doubletree by Hilton Cape Cod - Hyannis 287 Iyannough Rd Hyannis MA $130 nightly $149 total Feb 22 - Feb 23 Total with taxes and fees 8.2/10 Very Good! (888 reviews) [](https://expedia.com/Hyannis-Hotels-Doubletree-By-Hilton-Cape-Cod-Hyannis.h40461.Hotel-Information) Still don't see what you're looking for? [See all properties in Barnstable.](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=2%2F8%2F2026&endDate=2%2F9%2F2026®ionId=9658&star=50) You can also use these popular filters to refine your search. [Pool](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=2%2F8%2F2026&endDate=2%2F9%2F2026®ionId=9658&star=50&star=50&amenities=POOL)[Spa](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=2%2F8%2F2026&endDate=2%2F9%2F2026®ionId=9658&star=50&star=50&amenities=SPA_ON_SITE)[Hot tub](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=2%2F8%2F2026&endDate=2%2F9%2F2026®ionId=9658&star=50&star=50&amenities=HOT_TUB)[Breakfast included](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=2%2F8%2F2026&endDate=2%2F9%2F2026®ionId=9658&star=50&star=50&amenities=FREE_BREAKFAST)[Waterpark](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=2%2F8%2F2026&endDate=2%2F9%2F2026®ionId=9658&star=50&star=50&amenities=WATER_PARK) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Learn more about Barnstable Stroll along Hyannis Harbor, where you can watch fishing boats and ferries, or hop aboard a whale-watching cruise. Explore the John F. Kennedy Hyannis Museum, then unwind on sandy Craigville Beach or take a scenic drive through quaint Cape Cod villages. [See all hotels in Barnstable](https://www.expedia.com/Hotel-Search?startDate=2026-02-21&endDate=2026-02-22&adults=2®ionId=9658) ![Barnstable featuring an administrative buidling](https://images.trvl-media.com/place/9658/a910463a-b0d0-4b35-9d10-67783050d4b0.jpg?impolicy=fcrop&w=900&h=506&p=1&q=high) ## Top Barnstable Hotel Reviews ![Chatham Bars Inn](https://images.trvl-media.com/lodging/1000000/20000/19200/19139/w5700h3895x0y5-016d240d_y.jpg) ### Chatham Bars Inn 10/10 Excellent "Beautiful property " [](https://expedia.com/Chatham-Hotels-Chatham-Bars-Inn.h19139.Hotel-Information) ## Find out more about Barnstable There's nothing wrong with enjoying the finer things in life. Indulge yourself on your upcoming leisure time. There's no reason to delay a getaway to Barnstable any longer. You'll join the multitudes of vacationers who have made Barnstable so fashionable recently. Besides that, you'll find that these hotels are kept in fantastic condition and provide a fine place to kick back after your daily adventures. You deserve an outstanding getaway. Book one of Expedia's luxurious 5-star hotels in Barnstable and get ready to enjoy the getaway of a lifetime. ### Book the Best Barnstable 5-Star Hotels Don't be afraid to request the best service from your hotel, along with the best conditions. Top-notch service, delicious meals, and attentive guest service are all ready for you. You're sure to find exactly the accommodation you need. Besides that, you'll find that these hotels are kept in fantastic condition and provide a fine place to lay your head at night. How do you want to relax? 24-hour room service, so you can order that chocolate soufflé© in the wee hours of the morning? A mud wrap treatment that will leave you feeling great? Butler services? Whatever it is your heart desires, you're bound to find it here. Don't want to take our word for it? Plenty of visitors recommend this location. But you aren't going to spend your entire vacation in your room, of course. Don't worry. From doing a bit of shopping to embracing the great outdoors, you'll never be bored on this retreat. No matter what you end up doing, the 5-star hotels in Barnstable are waiting for you to relax after a busy day. ### Make Your Escape The results are in, and Barnstable 5-star hotels are the place to be when you book your next vacation. Many visitors recommend a trip to this location, so don't wait any longer. Expedia can help you land a great deal on accommodation. It's time to plan your next great escape. Select one of the 5-star hotels in Barnstable today and decompress in complete comfort tomorrow. ## Frequently asked questions ### How much does it cost to stay in a 5-star hotel in Barnstable? > - Search for the lowest price per night from $149 ### What makes a hotel 5 stars in Barnstable? ### Are there any 5-star all-inclusive resorts in Barnstable? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rentals - Other - [Cape Cod Hotels ](https://www.expedia.com/Cape-Cod-Hotels.d180061.Travel-Guide-Hotels) - [Hotels near Coast Guard Heritage Museum ](https://www.expedia.com/Coast-Guard-Heritage-Museum-Hotels.0-l6287251-0.Travel-Guide-Filter-Hotels) - [Hotels near Barnstable Old Gaol ](https://www.expedia.com/Barnstable-Old-Gaol-Hotels.0-l6287165-0.Travel-Guide-Filter-Hotels) - [Hotels near Barnstable Superior Courthouse ](https://www.expedia.com/Barnstable-Superior-Courthouse-Hotels.0-l553248621532666533-0.Travel-Guide-Filter-Hotels) - [Hotels near Barnstable Harbor ](https://www.expedia.com/Barnstable-Harbor-Hotels.0-l6293714-0.Travel-Guide-Filter-Hotels) - 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[Flights from Minneapolis (MSP) to Hyannis (HYA) ](https://www.expedia.com/lp/flights/msp/hya/minneapolis-to-hyannis) - [Flights from Kansas City (MCI) to Hyannis (HYA) ](https://www.expedia.com/lp/flights/mci/hya/kansas-city-to-hyannis) - [Flights from Fort Myers (RSW) to Hyannis (HYA) ](https://www.expedia.com/lp/flights/rsw/hya/fort-myers-to-hyannis) - [Flights from San Diego (SAN) to Hyannis (HYA) ](https://www.expedia.com/lp/flights/san/hya/san-diego-to-hyannis) - [Flights from Miami (MIA) to Hyannis (HYA) ](https://www.expedia.com/lp/flights/mia/hya/miami-to-hyannis) - [Flights from Phoenix (PHX) to Hyannis (HYA) ](https://www.expedia.com/lp/flights/phx/hya/phoenix-to-hyannis) - [Trayser Museum Complex ](https://www.expedia.com/Trayser-Museum-Complex-Barnstable.d553248621532666534.Vacation-Attraction) - [Coast Guard Heritage Museum ](https://www.expedia.com/Coast-Guard-Heritage-Museum-Barnstable.d6287251.Vacation-Attraction) - [Barnstable Old Gaol ](https://www.expedia.com/Barnstable-Old-Gaol-Barnstable.d6287165.Vacation-Attraction) - 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