Find hotels in Myrtle, MS from $66

The best time to visit Myrtle, Mississippi, is during the spring (April to May) and fall (September to October) when the weather is most pleasant.During these months, you'll find comfortable temperatures, typically ranging from the 60s to high 70s Fahrenheit, making it ideal for exploring the natural beauty of the area. Spring brings blooming wildflowers and lush greenery, while fall offers colorful foliage, particularly around the Holly Springs National Forest, which is just a short drive away. These seasons avoid the high humidity and heat of summer and the cooler, sometimes wet, days of winter.For those interested in outdoor activities like hiking or birdwatching, spring and fall provide the most agreeable conditions. The milder weather makes a stroll through the downtown area, with its historic buildings and local shops, quite enjoyable.

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