A calm river with clear water, surrounded by dense trees and rocky banks.

O Brien Vacation Rentals

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Check prices for these dates

In two weeks
Oct 16 - Oct 18
In two months
Nov 27 - Nov 29
In three months
Dec 25 - Dec 27
In four months
Jan 22 - Jan 24

Our top choices for O Brien vacation rentals

A covered porch with wooden railings, a table, and four chairs.

1. Suwannee Music Park about 30 mins away. Royal Springs across the street.

Suwannee Music Park about 30 mins away. Royal Springs across the street.
O'Brien
9.6 out of 10, Exceptional, (7 reviews)
"Ideal for weekend getaways, a quiet place to forget about the stress of the city, the house is so cozy. "
Mexico
Maria Josefina
$268 nightly
The price is $291
Oct 9 - Oct 10
Total with taxes and fees
Suwannee Music Park about 30 mins away. Royal Springs across the street.
Interior

2. Suwannee River Retreat: Pet Friendly, Private Dock

Suwannee River Retreat: Pet Friendly, Private Dock
3.0 star property
Branford
$567 nightly
The price is $606
Oct 4 - Oct 5
Total with taxes and fees
Suwannee River Retreat: Pet Friendly, Private Dock
Screened-In Lanai | Dining Table | Bar Area | Private Pool (Not Heated)

3. Suwannee River Retreat: Pet Friendly, Private Dock

Suwannee River Retreat: Pet Friendly, Private Dock
Branford
9.8 out of 10, Exceptional, (8 reviews)
"I had the pleasure of celebrating my birthday at the Bucks River Retreat. We had a group of 8 adults and 2 kids staying there and there was plenty of room for every one. The house is clean and cozy with a fun cabin vibe. The property is absolutely gorgeous! Plenty of room to park, party, cook out, swim and of course enjoy the Suwannee river. The dock is newly redone and fun place to hang out. I can’t wait to go back and stay at the Bucks again. It had every thing you need and so much more."
United States
Hayley
$572 nightly
The price is $607
Oct 4 - Oct 5
Total with taxes and fees
Suwannee River Retreat: Pet Friendly, Private Dock
Cozy tiny home living area with leather sofa and loft.

4. Nook at the Springs | Tiny Home • Full Kitchen

Nook at the Springs | Tiny Home • Full Kitchen
Fort White
9.8 out of 10, Exceptional, (10 reviews)
"Excellent place "
United States
Linay
$159 nightly
The price is $170
Oct 4 - Oct 5
Total with taxes and fees
Nook at the Springs | Tiny Home • Full Kitchen
Private kitchen

5. Cozy Lake House, Hot Tub & Close to FL Springs

Cozy Lake House, Hot Tub & Close to FL Springs
Branford
10.0 out of 10, Exceptional, (1 review)
"Juan was so welcoming. The house was clean and had everything we needed for a fun family getaway - and then some! Would love to stay here again. "
United States
Ashley L.
$248 nightly
The price is $264
Oct 5 - Oct 6
Total with taxes and fees
Cozy Lake House, Hot Tub & Close to FL Springs
A cabin with a cozy interior, a dining area, and a view of the forest.

6. Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy
2.0 star property
High Springs
10.0 out of 10, Exceptional, (285 reviews)
"Great accommodations! We enjoyed our stay and will be back!"
United States
Michael
$198 nightly
The price is $218
Nov 1 - Nov 2
Total with taxes and fees
Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy
A covered outdoor seating area with wicker chairs and a table, surrounded by a wooden deck and railing.

7. Rustic River Cabin 2-bedroom cabin in Branford near Santa Fe River

Rustic River Cabin 2-bedroom cabin in Branford near Santa Fe River
Branford
10.0 out of 10, Exceptional, (12 reviews)
"Hosts are awesome, and there's enough amenities to keep any family busy for as long as they'd like. "
United States
James S.
$248 nightly
The price is $270
Oct 5 - Oct 6
Total with taxes and fees
Rustic River Cabin 2-bedroom cabin in Branford near Santa Fe River
A modern kitchen with wooden cabinets, a central island with stools, a stove, and a dining area with chairs.

8. The Riverhead | Springs • Pavilion • Grill

The Riverhead | Springs • Pavilion • Grill
Fort White
9.4 out of 10, Exceptional, (16 reviews)
"Very close to springs and other attractions. Property was clean and very inviting on the inside. The beds were comfortable and the decor was very homey. Ample coffee and tea was provided and the kitchen was very equipped for cooking. Overall a really great way to enjoy the nearby springs. "
United States
Nicole
$260 nightly
The price is $279
Oct 13 - Oct 14
Total with taxes and fees
The Riverhead | Springs • Pavilion • Grill
A wooden deck with a table and chairs, large windows, and a ceiling light.

9. The Chalet On the Suwannee River

The Chalet On the Suwannee River
Mayo
10.0 out of 10, Exceptional, (1 review)
"We were in the area to check out some local spring and loved the accessibility of this VRBO’s location. This property was amazing and super fun. Can’t wait to go back."
United States
Mandy B.
$254 nightly
The price is $270
Oct 4 - Oct 5
Total with taxes and fees
The Chalet On the Suwannee River
A wooden staircase leading to a riverbank with a view of the water and surrounding trees.

10. The Best memories are made on the Suwannee River

The Best memories are made on the Suwannee River
Mayo
9.8 out of 10, Exceptional, (58 reviews)
"Was there for a family reunion and was great for what we needed."
United States
Anonymous traveler
$235 nightly
The price is $250
Oct 3 - Oct 4
Total with taxes and fees
The Best memories are made on the Suwannee River
A kitchen with wooden cabinets, a stainless steel refrigerator, and a window overlooking greenery.

11. Cozy Cabin Near SOSMP | Hulaween | Roots Revival

Cozy Cabin Near SOSMP | Hulaween | Roots Revival
Live Oak
10.0 out of 10, Exceptional, (36 reviews)
"Fantastic place, super clean and dreamy! We had an amazing stay"
United States
Maria C.
$164 nightly
The price is $178
Oct 5 - Oct 6
Total with taxes and fees
Cozy Cabin Near SOSMP | Hulaween | Roots Revival
A garden with a small pond, surrounded by various plants and a wooden structure.

12. Kokomo Farms - Cozy Cottage on the Farm

Kokomo Farms - Cozy Cottage on the Farm
Live Oak
9.8 out of 10, Exceptional, (15 reviews)
"Great place for nature!"
United States
Stephen
$154 nightly
The price is $167
Oct 3 - Oct 4
Total with taxes and fees
Kokomo Farms - Cozy Cottage on the Farm
A covered outdoor seating area with a round wooden table, white wicker chairs, and a black grill.

13. < 1 Mi From Suwannee River, Hideaway w/ Lanai

< 1 Mi From Suwannee River, Hideaway w/ Lanai
3.0 star property
Old Town
9.0 out of 10, Wonderful, (2 reviews)
"The Air B & B was amazing. The property and the A B & B was awesone, Clean, Quiet and very comfortable. Although some nights got a bit chilly and this property only had AC no heat. We managed just fine. We left it in perfect conditions according to the directions they wanted it left in. Thank you so much and we will be renting again. We also would recommend this to others. "
United States
Karen
$352 nightly
The price is $387
Oct 3 - Oct 4
Total with taxes and fees
< 1 Mi From Suwannee River, Hideaway w/ Lanai
A residential street lined with mature trees and a well-maintained lawn.

14. "The Loft" on the 11th Tee. No pets! No smoking!

"The Loft" on the 11th Tee. No pets! No smoking!
Lake City
10.0 out of 10, Exceptional, (17 reviews)
"This property is exactly as advertised - cozy, clean and well maintained in a beautiful neighborhood. We very much enjoyed staying there."
United States
Gerald S.
$153 nightly
The price is $170
Oct 5 - Oct 6
Total with taxes and fees
"The Loft" on the 11th Tee. No pets! No smoking!
A wooden deck with two benches and a table, surrounded by a wooden fence and trees.

15. SpringHouse at Convict Springs

SpringHouse at Convict Springs
Mayo
10.0 out of 10, Exceptional, (1 review)
$130 nightly
The price is $138
Oct 4 - Oct 5
Total with taxes and fees
SpringHouse at Convict Springs
A single-story mobile home with a covered porch and a fenced entrance.

16. Three Rivers Retreat

Three Rivers Retreat
Fort White
$265 nightly
The price is $294
Oct 4 - Oct 5
Total with taxes and fees
Three Rivers Retreat
A compact, well-lit room with a bed, a small sink, a potted plant, and a window with a view of the outdoors.

17. The Happy House Tiny Guest House

The Happy House Tiny Guest House
Live Oak
8.6 out of 10, Excellent, (8 reviews)
"very nice tiny house style accommodation"
United States
Cara B.
$134 nightly
The price is $145
Oct 3 - Oct 4
Total with taxes and fees
The Happy House Tiny Guest House
A modern kitchen with white cabinets, granite countertops, a black refrigerator, and a stainless steel stove.

18. Cozy Apartment in Lake City, only minutes from the baseball fields and food!

Cozy Apartment in Lake City, only minutes from the baseball fields and food!
Lake City
10.0 out of 10, Exceptional, (8 reviews)
"Great property!"
United States
Ashley S.
$448 nightly
The price is $497
Oct 3 - Oct 4
Total with taxes and fees
Cozy Apartment in Lake City, only minutes from the baseball fields and food!
A living room with two black leather sofas, a glass coffee table, a patterned rug, and a painting on the wall.

19. Modern 5BR Live Oak Haven – Minutes from Suwannee Music Park & Springs!

Modern 5BR Live Oak Haven – Minutes from Suwannee Music Park & Springs!
Live Oak
10.0 out of 10, Exceptional, (1 review)
"We were in town for a baseball state tournament. This was a fantastic place to stay for multiple families. This house has been newly updated and is beautiful in the inside. It was a very short distance to the Sportsplex. The host is very responsive and helpful. I highly recommend this house to all those families coming into Live Oak!"
United States
Tara W.
$596 nightly
The price is $649
Oct 7 - Oct 8
Total with taxes and fees
Modern 5BR Live Oak Haven – Minutes from Suwannee Music Park & Springs!
A covered outdoor dining area with a table and chairs, large windows, and a view of greenery.

20. A-frame on the Suwannee River Rendezvous

A-frame on the Suwannee River Rendezvous
Mayo
6.0 out of 10, (1 review)
"Overnight night enroute"
Canada
Doug M.
$265 nightly
The price is $281
Oct 4 - Oct 5
Total with taxes and fees
A-frame on the Suwannee River Rendezvous
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top O Brien Hotel Reviews

Hampton Inn & Suites Lake City

Hampton Inn & Suites Lake City

8/10 Good
"Clean hotel."
Cheryl 1-night trip
Posted 1 day ago
Hampton Inn & Suites Lake City

Find out more about O Brien

Everything you need to know about O Brien vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the O Brien vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect O Brien vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

O Brien vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in O Brien. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit O Brien in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $91 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on O Brien rentals

At Expedia, we put the best O Brien vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top O Brien rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream O Brien vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around O Brien. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

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Frequently asked questions

Can I find a vacation rental in O Brien?

Yes, we offer vacation rentals close to well known points of interest in O Brien, or you can go with a more secluded option if you're looking for a relaxing stay.

What's the top vacation rental that O Brien has to offer?

Royal Springs Riverfront Retreat on 3 acres, kayak/canoe, boat ramp, huge decks!: Visitors like this O Brien vacation home rental. It is located on the beach and has a balcony, a garden, and a barbecue grill to put you at ease in your new surroundings. It has 3 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. You and your friends and family can relax into your vacation with amenities like a selection of games. Another good choice for your trip to O Brien is MARGARITAVILLE BY THE SUWANNEE RIVER & ROYAL SPRINGS PET FRIENDLY.

How many vacation rentals are there in O Brien?

Expedia has 4 vacation rentals for your stay in O Brien.

What’s there to see and do in O Brien?

Suwannee River and Ichetucknee River are a couple of lovely local spots to get outside and enjoy nature. Ichetucknee Springs State Park and Lafayette Blue Springs State Park are a couple of places you'll find in the larger area.

What’s a vacation rental in O Brien like?

Vacation rentals are private properties you can stay in for several days or longer in O Brien. Vacation rentals offer amenities like WiFi and washers and dryers so you'll have everything you need. If you're concerned about a sanitized environment, a vacation rental can offer a sense of privacy away from public hotel elevators and bustling concierge desks while still allowing you the excitement and enjoyment of travel. You'll also have more space in a vacation rental than in a standard hotel, which is another reason why a vacation rental is a popular choice for small groups.