$538 Cheap Flights from Santo Domingo (SDQ) to Reynosa (REX)

View $538 flight on Wed, Nov 19, 2025Opens in a new window

Popular airlines from Las Americas Intl. Airport (SDQ) to Reynosa, Tamaulipas (REX-General Lucio Blanco Intl.)

Cheap Flights from Santo Domingo to Reynosa (SDQ-REX)

Prices were available within the past 7 days and start at $538 for one-way flights and for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Alternative airports near Reynosa

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Miller Intl. MFE. Cheapest option available. Average driving time to city center is 1 hour 3 minutes. Flights from $672
MFE
Miller Intl.
Cheapest
Average driving time to city center1 h 3 min
Flights from $672
Flights from Santo Domingo (SDQ) to Reynosa (REX)
Origin airport
Las Americas Intl.
Destination airport
General Lucio Blanco Intl.
Distance
1895 mi

Santo Domingo to Reynosa Flights

The cheapest times to fly from Santo Domingo to Reynosa

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Santo Domingo to Reynosa are during the month of . You can find some of the cheapest flights from Santo Domingo to Reynosa with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Santo Domingo to Reynosa

Sunday is one of the best days to book for cheap flights from Santo Domingo to Reynosa: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Santo Domingo to Reynosa

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Santo Domingo to Reynosa in 2025. You can also book with separate airlines for your outbound and return journeys, from $538 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Santo Domingo to Reynosa flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Santo Domingo to Reynosa airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Las Americas Intl. Airport (SDQ) to General Lucio Blanco Intl. Airport (REX) cost?
Snag a cheap one-way flight from $538 or cheap return flight from Las Americas Intl. Airport (SDQ) to General Lucio Blanco Intl. Airport (REX) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight deals on this route.
What is the cheapest month to fly from Las Americas Intl. Airport (SDQ) to General Lucio Blanco Intl. Airport (REX)?
The cheapest month to fly from SDQ to REX is , when demand is low. Off-peak season is usually when you'll find lower airfares between these airports.
What is the cheapest airline that flies from Las Americas Intl. Airport (SDQ) to General Lucio Blanco Intl. Airport (REX)?
To find the cheapest airline flying from SDQ to REX, use Expedia's filter tool. Customize your search based on what matters most to you, such as preferred carriers and cabin class. You can then sort your results by "Price (lowest to highest)" to see the cheapest fares upfront.
How many flights per day from Las Americas Intl. Airport (SDQ) to General Lucio Blanco Intl. Airport (REX)?
You'll need to catch a flight with a layover when traveling from Las Americas Intl. Airport (SDQ) to General Lucio Blanco Intl. Airport (REX). There are no daily direct flights on this route. However, simply filter your search to include one or two stops to find an option that works for you.
What day of the week has the most flights from SDQ to REX?
Friday is usually the busiest day for flights, while Tuesday tends to be the quietest.* Remember that flight schedules can vary depending on a number of factors, such as the carrier and season.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Las Americas Intl. Airport (SDQ) to General Lucio Blanco Intl. Airport (REX)?
To avoid potential delays on the Las Americas Intl. Airport (SDQ) to General Lucio Blanco Intl. Airport (REX) route, fly before 3 PM. Departures after this hour have a 22% higher chance of cancellation.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Las Americas Intl. Airport (SDQ) to General Lucio Blanco Intl. Airport (REX) last-minute?
Last-minute fares from SDQ to REX are usually more expensive. To lock in the best rates, start looking for flights as early as possible. That said, if you're flexible with your travel plans, you may score a cheap fare right before your trip.
Is it cheaper to book a SDQ to REX flight and hotel package?
Compared with arranging flights and hotels separately, booking a SDQ to REX flight and hotel package with Expedia could result in significant savings. Better still, having it all in one place will take the stress out of travel planning. Simply secure your flights and select from our extensive range of hotels, then personalize your trip with extras like tours, car rentals and activities.
Can I cancel or change the date of my flight from Las Americas Intl. Airport (SDQ) to General Lucio Blanco Intl. Airport (REX)?
If you reserved your SDQ to REX flight in the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the ticket type you purchased, additional charges may apply for changes beyond that time. Airline policies and contact information can be found in your itinerary or confirmation email. Or, go to our Customer Service portal if you'd like more information.

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*Available to One Key members.