$266 Cheap Flights from Santo Domingo (SDQ) to Reynosa (REX)

View $266 flight on Thu, Dec 25, 2025Opens in a new window

Popular airlines from Las Americas Intl. Airport (SDQ) to Reynosa, Tamaulipas (REX-General Lucio Blanco Intl.)

Cheap Flights from Santo Domingo to Reynosa (SDQ-REX)

Prices were available within the past 7 days and start at $266 for one-way flights and $603 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Aeromexico
Tue, Oct 21 - Mon, Nov 10
SDQ
Santo Domingo
REX
Reynosa
$603 Roundtrip, found 2 days ago
$603
Roundtrip
found 2 days ago
Select Aeromexico flight, departing Tue, Oct 21 from Santo Domingo to Reynosa, returning Mon, Nov 10, priced at $603 found 2 days ago
Aeromexico
Mon, Nov 3 - Sun, Nov 16
SDQ
Santo Domingo
REX
Reynosa
$605 Roundtrip, found 2 days ago
$605
Roundtrip
found 2 days ago
Select Aeromexico flight, departing Mon, Nov 3 from Santo Domingo to Reynosa, returning Sun, Nov 16, priced at $605 found 2 days ago
Aeromexico
Tue, Sep 30 - Sat, Oct 18
SDQ
Santo Domingo
REX
Reynosa
$610 Roundtrip, found 2 days ago
$610
Roundtrip
found 2 days ago
Select Aeromexico flight, departing Tue, Sep 30 from Santo Domingo to Reynosa, returning Sat, Oct 18, priced at $610 found 2 days ago
Aeromexico
Sat, Oct 25 - Mon, Nov 10
SDQ
Santo Domingo
REX
Reynosa
$615 Roundtrip, found 2 days ago
$615
Roundtrip
found 2 days ago
Select Aeromexico flight, departing Sat, Oct 25 from Santo Domingo to Reynosa, returning Mon, Nov 10, priced at $615 found 2 days ago
Aeromexico
Sat, Oct 11 - Thu, Oct 30
SDQ
Santo Domingo
REX
Reynosa
$621 Roundtrip, found 2 days ago
$621
Roundtrip
found 2 days ago
Select Aeromexico flight, departing Sat, Oct 11 from Santo Domingo to Reynosa, returning Thu, Oct 30, priced at $621 found 2 days ago
Aeromexico
Tue, Sep 30 - Wed, Oct 22
SDQ
Santo Domingo
REX
Reynosa
$622 Roundtrip, found 2 days ago
$622
Roundtrip
found 2 days ago
Select Aeromexico flight, departing Tue, Sep 30 from Santo Domingo to Reynosa, returning Wed, Oct 22, priced at $622 found 2 days ago
Aeromexico
Sat, Oct 18 - Sun, Nov 2
SDQ
Santo Domingo
REX
Reynosa
$627 Roundtrip, found 2 days ago
$627
Roundtrip
found 2 days ago
Select Aeromexico flight, departing Sat, Oct 18 from Santo Domingo to Reynosa, returning Sun, Nov 2, priced at $627 found 2 days ago
Aeromexico
Tue, Sep 30 - Thu, Oct 23
SDQ
Santo Domingo
REX
Reynosa
$629 Roundtrip, found 2 days ago
$629
Roundtrip
found 2 days ago
Select Aeromexico flight, departing Tue, Sep 30 from Santo Domingo to Reynosa, returning Thu, Oct 23, priced at $629 found 2 days ago
Aeromexico
Tue, Sep 30 - Sun, Oct 19
SDQ
Santo Domingo
REX
Reynosa
$633 Roundtrip, found 2 days ago
$633
Roundtrip
found 2 days ago
Select Aeromexico flight, departing Tue, Sep 30 from Santo Domingo to Reynosa, returning Sun, Oct 19, priced at $633 found 2 days ago
Aeromexico
Sat, Sep 27 - Wed, Oct 15
SDQ
Santo Domingo
REX
Reynosa
$637 Roundtrip, found 2 days ago
$637
Roundtrip
found 2 days ago
Select Aeromexico flight, departing Sat, Sep 27 from Santo Domingo to Reynosa, returning Wed, Oct 15, priced at $637 found 2 days ago

Frequently asked questions

How much does a flight from Las Americas Intl. Airport (SDQ) to General Lucio Blanco Intl. Airport (REX) cost?
Snag a cheap one-way flight from $266 or cheap return flight from $603 from Las Americas Intl. Airport (SDQ) to General Lucio Blanco Intl. Airport (REX) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight deals on this route.
What is the cheapest month to fly from Las Americas Intl. Airport (SDQ) to General Lucio Blanco Intl. Airport (REX)?
The cheapest month to fly from SDQ to REX is October, when demand is low. Off-peak season is usually when you'll find lower airfares between these airports.
What is the cheapest airline that flies from Las Americas Intl. Airport (SDQ) to General Lucio Blanco Intl. Airport (REX)?
To find the cheapest airline flying from SDQ to REX, use Expedia's filter tool. Customize your search based on what matters most to you, such as preferred carriers and cabin class. You can then sort your results by "Price (lowest to highest)" to see the cheapest fares upfront.
How many flights per day from Las Americas Intl. Airport (SDQ) to General Lucio Blanco Intl. Airport (REX)?
You'll need to catch a flight with a layover when traveling from Las Americas Intl. Airport (SDQ) to General Lucio Blanco Intl. Airport (REX). There are no daily direct flights on this route. However, simply filter your search to include one or two stops to find an option that works for you.
What day of the week has the most flights from SDQ to REX?
Friday is usually the busiest day for flights, while Tuesday tends to be the quietest.* Remember that flight schedules can vary depending on a number of factors, such as the carrier and season.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Las Americas Intl. Airport (SDQ) to General Lucio Blanco Intl. Airport (REX)?
To avoid potential delays on the Las Americas Intl. Airport (SDQ) to General Lucio Blanco Intl. Airport (REX) route, fly before 3 PM. Departures after this hour have a 22% higher chance of cancellation.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Las Americas Intl. Airport (SDQ) to General Lucio Blanco Intl. Airport (REX) last-minute?
Last-minute fares from SDQ to REX are usually more expensive. To lock in the best rates, start looking for flights as early as possible. That said, if you're flexible with your travel plans, you may score a cheap fare right before your trip.
Is it cheaper to book a SDQ to REX flight and hotel package?
Compared with arranging flights and hotels separately, booking a SDQ to REX flight and hotel package with Expedia could result in significant savings. Better still, having it all in one place will take the stress out of travel planning. Simply secure your flights and select from our extensive range of hotels, then personalize your trip with extras like tours, car rentals and activities.
Can I cancel or change the date of my flight from Las Americas Intl. Airport (SDQ) to General Lucio Blanco Intl. Airport (REX)?
If you reserved your SDQ to REX flight in the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the ticket type you purchased, additional charges may apply for changes beyond that time. Airline policies and contact information can be found in your itinerary or confirmation email. Or, go to our Customer Service portal if you'd like more information.

Travel information

Travel information

Origin airport
Las Americas Intl.
Destination airport
General Lucio Blanco Intl.
Roundtrip price
$603
Distance
1895 mi

Book with confidence

Book with confidence

Santo Domingo to Reynosa Flights

The cheapest times to fly from Santo Domingo to Reynosa

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Santo Domingo to Reynosa are during the month of October. You can find some of the cheapest flights from Santo Domingo to Reynosa with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Santo Domingo to Reynosa

Sunday is one of the best days to book for cheap flights from Santo Domingo to Reynosa: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Santo Domingo to Reynosa

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Santo Domingo to Reynosa in 2025. You can also book with separate airlines for your outbound and return journeys, from $266 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Santo Domingo to Reynosa flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Santo Domingo to Reynosa airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Santo Domingo to Reynosa Flights

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*Available to One Key members.