Find all hotels by Motel 6 in Upstate South Carolina, SC from $62
Check prices for these dates
Compare rooms and suites by Motel 6 in Upstate South Carolina with rates, reviews, and availability. Most hotels are fully refundable.
Our top choices for Upstate South Carolina Motel 6
Motel 6 Greenville, SC - I-85 Near Downtown
Motel 6 Greenville, SC - I-85 Near Downtown
6.8 out of 10, (297)
$56 nightly
The price is $62
Sep 14 - Sep 15
Total with taxes and fees
Motel 6 Spartanburg, Sc – Northwest / Business 85
Motel 6 Spartanburg, Sc – Northwest / Business 85
7.4 out of 10, Good, (68)
$73 nightly
The price is $81
Sep 9 - Sep 10
Total with taxes and fees
Motel 6 Simpsonville, SC - Greenville
Motel 6 Simpsonville, SC - Greenville
7.2 out of 10, Good, (339)
$70 nightly
The price is $77
Sep 9 - Sep 10
Total with taxes and fees
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in
Top Upstate South Carolina Hotel Reviews
Hilton Greenville
10/10 Excellent
Grand Bohemian Lodge Greenville, Autograph Collection
10/10 Excellent
Explore a world of travel with Expedia
Explore a world of travel with Expedia
- Woodruff Hotels
- Cabin Rentals in Woodruff
- Motels in Woodruff
- B&B in Woodruff
- Pet-friendly Hotels in Woodruff
- RV Parks in Woodruff
- Vacation Homes in Woodruff
- 3 Star Hotels in Woodruff
- Cottages in Woodruff
- 4 Star Hotels in Woodruff
- Hotels near Tyger-10 Nature Park
- Roebuck Hotels
- 4 Star Hotels in Roebuck
- Apartments in Roebuck
- Cabin Rentals in Roebuck
- B&B in Roebuck
- 5 Star Hotels in Roebuck
- Cottages in Roebuck
- Motels in Roebuck
- Vacation Homes in Roebuck
- RV Parks in Roebuck
- Moore Hotels
- Hotels near Walnut Grove Plantation
- Enoree Hotels
- Cottages in Enoree
- Cabin Rentals in Enoree
- RV Parks in Enoree
- Hotels near Willow Creek Golf Club
- Pauline Hotels
- Motels in Pauline
- 5 Star Hotels in Pauline
- B&B in Pauline
- Reidville Hotels
- Cabin Rentals in Reidville
- 4 Star Hotels in Reidville
- 3 Star Hotels in Reidville
- Hotels near Tyger River Park
- Hotels near River Falls Golf Course
- Hotels near Tyger River Park
- Anglewood Hotels
- Flights to Woodruff
- Flights from Woodruff
- Flights to Roebuck
- Flights from Roebuck
- Flights from Moore
- Flights from Enoree
- Flights from Pauline
- Flights from Reidville
- Flights from Charlotte (CLT) to Spartanburg (SPA)
- Flights from Spartanburg Downtown Memorial
- Flights from Asheville (AVL) to Spartanburg (SPA)
- Flights from Atlanta (ATL) to Spartanburg (SPA)
- Flights from New York (JFK) to Spartanburg (SPA)
- Flights from Columbia (CAE) to Spartanburg (SPA)
- Flights from Greenville (GSP) to Spartanburg (SPA)
- Flights from Raleigh (RDU) to Spartanburg (SPA)
- Flights from Miami (MIA) to Spartanburg (SPA)
- Flights from Seattle (SEA) to Spartanburg (SPA)
- Flights from Buffalo (BUF) to Spartanburg (SPA)
- Flights from Hickory (HKY) to Spartanburg (SPA)
- Flights from Richmond (RIC) to Spartanburg (SPA)
- Flights from Charleston (CHS) to Spartanburg (SPA)
- Flights from Los Angeles (LAX) to Spartanburg (SPA)
- Flights from Tampa (TPA) to Spartanburg (SPA)
- Flights from Trenton (TTN) to Spartanburg (SPA)
- Flights from Philadelphia (PHL) to Spartanburg (SPA)
- Flights from Punta Gorda Airport (PGD) to Spartanburg (SPA)
- Flights from Vero Beach (VRB) to Spartanburg (SPA)
- Flights from Chicago (ORD) to Spartanburg (SPA)
- Flights from Latrobe (LBE) to Spartanburg (SPA)
- Flights from Evansville (EVV) to Spartanburg (SPA)
- Flights from Washington (DCA) to Spartanburg (SPA)
- Flights from Cape Girardeau (CGI) to Spartanburg (SPA)
- Flights from Wilmington (ILM) to Spartanburg (SPA)
- Flights from Boston (BOS) to Spartanburg (SPA)
- Flights from Dallas (DFW) to Spartanburg (SPA)
- Flights from Fort Lauderdale (FLL) to Spartanburg (SPA)
- Flights from Syracuse (SYR) to Spartanburg (SPA)
- Flights from Detroit (DTW) to Spartanburg (SPA)