A waterfall cascading over a rocky ledge into a calm river surrounded by lush greenery.

Find all hotels by America's Best Inns in Central, SC

  • Upfront pricing

    Our total price for your stay includes taxes and fees
  • Treat yourself

    Save 10% or more on over 100,000 hotels worldwide with Member Prices
    Learn about One Key
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
Oct 21 - Oct 22
Tomorrow
Oct 22 - Oct 23
This weekend
Oct 23 - Oct 25
Next weekend
Oct 30 - Nov 1
Save an average of 15% on thousands of hotels when you're signed in

Top Central Hotel Reviews

Clemson University's James F. Martin Inn

Clemson University's James F. Martin Inn

10/10 Excellent
"The room was on the ground level so walked out onto the gorgeous sprawling golf course and the lake and the beautiful pool/hot tub facilites. The location was great for where you meet to start a Clemson tour, however it's completely away from the main part of campus and the town otherwise, so nothing is really walkable from it. That's not a big deal b/c everything is a less than 5-10 min drive and the location is so pretty and peaceful it's worth it. we used the pool and hot tub at 8pm and were the only ones there and it was really lovely. The bed was incredibly hard, which was my only complaint."
Alina 1-night trip
Posted 17 hours ago
Clemson University's James F. Martin Inn
Hampton Inn & Suites Seneca-Clemson Area

Hampton Inn & Suites Seneca-Clemson Area

10/10 Excellent
"Room was clean and staff was friendly and helpful."
Sasha 1-night trip
Posted 17 hours ago
Hampton Inn & Suites Seneca-Clemson Area
Quality Inn Seneca US-123

Quality Inn Seneca US-123

10/10 Excellent
"Hotel was very clean and staff was very very pleasant."
ashlee 2-night trip
Posted 2 days ago
Quality Inn Seneca US-123
Best Western Plus Clemson Hotel & Conference Center

Best Western Plus Clemson Hotel & Conference Center

10/10 Excellent
"Great place to stay while visiting your kids at Clemson!"
Angela 2-night trip
Posted 2 days ago
Best Western Plus Clemson Hotel & Conference Center
Days Inn by Wyndham Anderson

Days Inn by Wyndham Anderson

10/10 Excellent
"The rooms were clean. It was convenient to what we needed. The breakfast advertised online mentioned tea, juice and fruit, but there weren't any. Only coffee, which was disappointing. Everything else was great."
Shannon 1-night trip
Posted 2 days ago
Days Inn by Wyndham Anderson
Comfort Inn & Suites Clemson - University Area

Comfort Inn & Suites Clemson - University Area

10/10 Excellent
"Updated room and friendly staff."
Sherie 1-night trip
Posted 3 days ago
Comfort Inn & Suites Clemson - University Area
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

10/10 Excellent
"Very clean, had every thing you needed for a good trip. Wish they had some board games in the cabin but everything else was great."
Anonymous traveler 1-night trip
Posted 3 days ago
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
The Abernathy of Clemson

The Abernathy of Clemson

8/10 Good
"The hotel staff was very nice. The room and property were clean. Right across the street from campus and close to lots of food options. Parking was included. They do not have an onsite gym and did not have a store with necessities such as medicine."
Jennifer 1-night trip
Posted 6 days ago
The Abernathy of Clemson
Tru by Hilton Seneca Clemson

Tru by Hilton Seneca Clemson

10/10 Excellent
"The staff were very friendly and everything was nice and clean! A great selection for breakfast!"
Alexis 2-night trip
Posted 6 days ago
Tru by Hilton Seneca Clemson

Explore a world of travel with Expedia