Title: Top America's Best Inns in Central, SC - Expedia.com [Central Travel Guide](https://expedia.com/Central.dx10503)[Hotels in Central](https://expedia.com/Central-Hotels.d10503.Travel-Guide-Hotels)[Vacation Rentals in Central](https://expedia.com/Central-Vacation-Rentals.d10503.Travel-Guide-VacationRentals)[Flights to Central](https://expedia.com/Cheap-Flights-To-Central.d10503.Travel-Guide-Flights)[Car Rentals in Central](https://expedia.com/Car-Rentals-In-Central.d10503.Car-Rental-Guide)[Central Vacation Packages](https://expedia.com/Central.d10503.Destination-Travel-Guides) ![Todd Creek Falls](https://images.trvl-media.com/place/10503/baefe116-5881-466e-b320-6ded2828ee1d.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/10503/baefe116-5881-466e-b320-6ded2828ee1d.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Upfront pricing Our total price for your stay includes taxes and fees - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save 10% or more on over 100,000 hotels worldwide with Member Prices [Learn about One Key](https://www.expedia.com/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Apr 1 - Apr 2](https://www.expedia.com/Hotel-Search?regionId=10503&startDate=2026-04-01&endDate=2026-04-02&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Apr 2 - Apr 3](https://www.expedia.com/Hotel-Search?regionId=10503&startDate=2026-04-02&endDate=2026-04-03&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Apr 3 - Apr 5](https://www.expedia.com/Hotel-Search?regionId=10503&startDate=2026-04-03&endDate=2026-04-05&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Apr 10 - Apr 12](https://www.expedia.com/Hotel-Search?regionId=10503&startDate=2026-04-10&endDate=2026-04-12&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.com/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FCentral-Hotels-Americas-Best-Inns.0-0-d10503--bAmericasBestInns.Travel-Guide-Filter-Hotels)[ Sign up, it's free ](https://expedia.com/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FCentral-Hotels-Americas-Best-Inns.0-0-d10503--bAmericasBestInns.Travel-Guide-Filter-Hotels) ## Top Central Hotel Reviews ![The Shepherd Hotel Downtown Clemson](https://images.trvl-media.com/lodging/88000000/87690000/87688200/87688155/bd45b45c_y.jpg) ### The Shepherd Hotel Downtown Clemson 10/10 Excellent "Limited menu available on site but many places nearby in walking distance." [](https://expedia.com/Clemson-Hotels-The-Shepherd-Hotel-Downtown-Clemson.h87688155.Hotel-Information) ![Woodspring Suites Anderson North I-85](https://images.trvl-media.com/lodging/115000000/114350000/114348700/114348655/220e9886_y.jpg) ### Woodspring Suites Anderson North I-85 2/10 Terrible "Heat and air did not work. Kiosk for external front desk was manned by broken English attendant from India making communication quite difficult. Once moved to alternate room, plugged laptop in to charge and the circuit breaker tripped due to overload. The final awful rating comes from the mattress which felt as if it were more firm than a granite countertop! I will avoid Woodbridge Suites at any cost!" [](https://expedia.com/Anderson-Hotels-Woodspring-Suites-Anderson-North-I-85.h114348655.Hotel-Information) ![Clemson University's James F. Martin Inn](https://images.trvl-media.com/lodging/9000000/8480000/8475000/8474950/ad943919_y.jpg) ### Clemson University's James F. Martin Inn 6/10 Okay "Very basic property amenities " [](https://expedia.com/Anderson-Hotels-Clemson-Universitys-James-F-Martin-Inn.h8474950.Hotel-Information) ![Best Western Plus Clemson Hotel & Conference Center](https://images.trvl-media.com/lodging/1000000/10000/1400/1370/w3837h2558x3y3-4efd29d6_y.jpg) ### Best Western Plus Clemson Hotel & Conference Center 6/10 Okay "Dirty hallways; terrible gym facilities." [](https://expedia.com/Anderson-Hotels-Best-Western-Plus-University-Inn-Conference-Center.h1370.Hotel-Information) ![Hampton Inn & Suites Seneca-Clemson Area](https://images.trvl-media.com/lodging/7000000/6700000/6696900/6696886/8f736b3a_y.jpg) ### Hampton Inn & Suites Seneca-Clemson Area 8/10 Good "The two desk clerk we interacted with were extra cheerful and very helpful. The breakfast was very good, as expected. The room was perfectly clean and fresh. Good beds, okay location, fairly priced. Would return again. " [](https://expedia.com/Anderson-Hotels-Hampton-Inn-Suites-Seneca-Clemson-Area.h6696886.Hotel-Information) ![Inn @ Clemson](https://images.trvl-media.com/lodging/1000000/90000/84700/84636/d257793d_y.jpg) ### Inn @ Clemson 4/10 Poor "Not a pleasant stay. Musty hallway & room. Zero housekeeping & stayed from Friday to Tuesday. Air conditioner was glitchy. Staff was minimally friendly. Needs updating badly. " [](https://expedia.com/Anderson-Hotels-Inn-Clemson.h84636.Hotel-Information) ![Days Inn by Wyndham Anderson](https://images.trvl-media.com/lodging/1000000/10000/6400/6344/bea0c9d1_y.jpg) ### Days Inn by Wyndham Anderson 10/10 Excellent "Jennifer at the front desk was very easy to work with. Thank you!" [](https://expedia.com/Anderson-Hotels-Days-Inn-By-Wyndham-Anderson.h6344.Hotel-Information) ![The Inn at Patrick Square](https://images.trvl-media.com/lodging/20000000/19520000/19511400/19511329/4d00561c_y.jpg) ### The Inn at Patrick Square 10/10 Excellent "One of the cleanest hotels we have ever stayed in. The staff was friendly and it was located in such a cute neighborhood area with shops and restaurants. " [](https://expedia.com/Anderson-Hotels-The-Inn-At-Patrick-Square.h19511329.Hotel-Information) ![Lakeside Lodge Clemson](https://images.trvl-media.com/lodging/41000000/40220000/40217400/40217319/db449d90_y.jpg) ### Lakeside Lodge Clemson 2/10 Terrible "I must have gotten the absolute worst room here. The last time I stayed I had a great room with a balcony. This time, I got a "patio," that I even paid extra for that connected to the parking lot overlooking the highway on the fist floor. The room smelled AWFUL. Then I realized it must have been a pet room. Smelled like dog urine and the front desk said they couldn't move me because I had booked through Expedia. They offered to spray the room. With what, I have no idea. Probably some kind of dog urine spray reducer. Gross. Very disappointed. " [](https://expedia.com/Anderson-Hotels-Lakeside-Lodge-Clemson.h40217319.Hotel-Information)