$523 Cheap Flights from Chicago (MDW) to Lyon (LYS)

View $523 flight on Wed, Nov 26, 2025Opens in a new window

Popular airlines from Chicago Midway Airport (MDW) to Saint-Exupery Airport (LYS)

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Cheap Flights from Chicago to Lyon (MDW-LYS)

Prices were available within the past 7 days and start at $523 for one-way flights and $792 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Delta
Fri, Mar 6 - Thu, Mar 12
MDW
Chicago
LYS
Lyon
$792 Roundtrip, found 6 days ago
$792
Roundtrip
found 6 days ago
Select Delta flight, departing Fri, Mar 6 from Chicago to Lyon, returning Thu, Mar 12, priced at $792 found 6 days ago
Virgin Atlantic
Mon, Nov 17 - Mon, Nov 24
MDW
Chicago
LYS
Lyon
$807 Roundtrip, found 3 days ago
$807
Roundtrip
found 3 days ago
Select Virgin Atlantic flight, departing Mon, Nov 17 from Chicago to Lyon, returning Mon, Nov 24, priced at $807 found 3 days ago
Delta
Wed, Jan 7 - Fri, May 15
MDW
Chicago
LYS
Lyon
$876 Roundtrip, found 6 days ago
$876
Roundtrip
found 6 days ago
Select Delta flight, departing Wed, Jan 7 from Chicago to Lyon, returning Fri, May 15, priced at $876 found 6 days ago
Delta
Sun, Nov 16 - Mon, Nov 24
MDW
Chicago
LYS
Lyon
$888 Roundtrip, found 3 days ago
$888
Roundtrip
found 3 days ago
Select Delta flight, departing Sun, Nov 16 from Chicago to Lyon, returning Mon, Nov 24, priced at $888 found 3 days ago
Delta
Sat, May 2 - Sat, May 9
MDW
Chicago
LYS
Lyon
$896 Roundtrip, found 4 days ago
$896
Roundtrip
found 4 days ago
Select Delta flight, departing Sat, May 2 from Chicago to Lyon, returning Sat, May 9, priced at $896 found 4 days ago
Virgin Atlantic
Wed, Jan 7 - Fri, May 15
MDW
Chicago
LYS
Lyon
$907 Roundtrip, found 6 days ago
$907
Roundtrip
found 6 days ago
Select Virgin Atlantic flight, departing Wed, Jan 7 from Chicago to Lyon, returning Fri, May 15, priced at $907 found 6 days ago
Delta
Sat, May 2 - Sat, May 9
MDW
Chicago
LYS
Lyon
$922 Roundtrip, found 4 days ago
$922
Roundtrip
found 4 days ago
Select Delta flight, departing Sat, May 2 from Chicago to Lyon, returning Sat, May 9, priced at $922 found 4 days ago
Air France
Sat, May 2 - Sat, May 9
MDW
Chicago
LYS
Lyon
$948 Roundtrip, found 4 days ago
$948
Roundtrip
found 4 days ago
Select Air France flight, departing Sat, May 2 from Chicago to Lyon, returning Sat, May 9, priced at $948 found 4 days ago
Delta
Wed, Jan 7 - Fri, May 15
MDW
Chicago
LYS
Lyon
$986 Roundtrip, found 6 days ago
$986
Roundtrip
found 6 days ago
Select Delta flight, departing Wed, Jan 7 from Chicago to Lyon, returning Fri, May 15, priced at $986 found 6 days ago
KLM
Sun, Nov 23 - Sun, Nov 30
MDW
Chicago
LYS
Lyon
$1,452 Roundtrip, just found
$1,452
Roundtrip
just found
Select KLM flight, departing Sun, Nov 23 from Chicago to Lyon, returning Sun, Nov 30, priced at $1,452 just found
Flights from Chicago (MDW) to Lyon (LYS)
Origin airport
Midway Intl.
Destination airport
Saint-Exupery
Airlines serving
Delta, KLM
Roundtrip price
$792
Distance
4363 mi

Chicago to Lyon Flights

The cheapest times to fly from Chicago to Lyon

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Chicago to Lyon are during the month of March. You can find some of the cheapest flights from Chicago to Lyon with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Chicago to Lyon

Sunday is one of the best days to book for cheap flights from Chicago to Lyon: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Chicago to Lyon

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Chicago to Lyon in 2025. You can also book with separate airlines for your outbound and return journeys, from $523 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Chicago to Lyon flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Chicago to Lyon airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Midway Intl. Airport (MDW) to Saint-Exupery Airport (LYS) cost?
Secure a cheap one-way flight from $523 or cheap return flight from $792 from Midway Intl. Airport (MDW) to Saint-Exupery Airport (LYS) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight offers on this route.
What is the cheapest month to fly from Midway Intl. Airport (MDW) to Saint-Exupery Airport (LYS)?
March is the cheapest month to fly from MDW to LYS. Timing your trip outside of the busy season is often the key to scoring lower fares.
What is the cheapest airline that flies from Midway Intl. Airport (MDW) to Saint-Exupery Airport (LYS)?
Use the filters on Expedia to compare different airlines and find the most affordable carrier that'll fly you from MDW to LYS. Then, sort your results by "Price (lowest to highest)" to pick up the best deal available.
How many flights per day from Midway Intl. Airport (MDW) to Saint-Exupery Airport (LYS)?
Direct flights from Midway Intl. Airport (MDW) to Saint-Exupery Airport (LYS) aren't available daily, so you'll have to take a flight with a layover. Explore your options with our filter tool. Enter your travel dates and select either "1 Stop" or "2+ Stops."
What day of the week has the most flights from MDW to LYS?
Generally you'll find the greatest selection of flight options on a Friday. Tuesdays tend to be the quietest.* However, this can change depending on the season, carrier and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Midway Intl. Airport (MDW) to Saint-Exupery Airport (LYS)?
To touch down at Saint-Exupery Airport (LYS) on schedule, book a flight that leaves from Midway Intl. Airport (MDW) before 3 PM. The chance of cancellations is 22% higher, on average, for departures after this hour.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Midway Intl. Airport (MDW) to Saint-Exupery Airport (LYS) last-minute?
Booking your flight from MDW to LYS shortly before your trip is generally more expensive. But if you're flexible with your travel times and dates, you could grab a cheap last-minute fare.
Is it cheaper to book a MDW to LYS flight and hotel package?
Booking a MDW to LYS flight and hotel package is generally cheaper than booking separately. With Expedia, you can enjoy the convenience of organizing your travels in one place. Select from our extensive range of stays and then add car rentals, activities and flights to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Midway Intl. Airport (MDW) to Saint-Exupery Airport (LYS)?
Generally, it's possible to cancel or reschedule your MDW to LYS flight. However, if the booking was made more than 24 hours ago, additional charges may apply. Refer to your airline's policies in your itinerary to see what changes are possible and whether any costs are involved. You'll also find further details on our Customer Service portal.

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*Available to One Key members.