The Colosseum in Rome with its arches and surrounding gardens.

$76 Cheap Flights from Santander (SDR) to Rome (ROM)

View $76 flight on Thu, Dec 31, 2026

Popular airlines from Santander (SDR) to Rome

Find the cheapest flights on Expedia from Santander (SDR) to Rome (ROM). Flight ticket prices change frequently based on availability and demand. We send price‑drop alerts to make air travel simple and flexible. The lowest one-way fare found on Expedia for this route in the past 7 days starts at $76 for travel on December 31, 2026.

Cheap Flights from Santander to Rome (SDR-ROM)

Prices were available within the past 7 days and start at $76 for one-way flights and $157 for roundtrip, for the period specified. Prices and availability are subject to change.

All deals

One way

Roundtrip

Select Vueling Airlines flight, departing Thu, Dec 31 from Santander to Rome, returning Sat, Jan 9, priced at $157 Found 3 days ago

Thu, Dec 31 - Sat, Jan 9 · SDR · FCO · Roundtrip

Select Iberia flight, departing Thu, Dec 31 from Santander to Rome, returning Sat, Jan 9, priced at $159 Found 3 days ago

Thu, Dec 31 - Sat, Jan 9 · SDR · FCO · Roundtrip

Select Vueling Airlines flight, departing Thu, Dec 31 from Santander to Rome, returning Sat, Jan 9, priced at $162 Found 3 days ago

Thu, Dec 31 - Sat, Jan 9 · SDR · FCO · Roundtrip

Select Vueling Airlines flight, departing Tue, Nov 17 from Santander to Rome, returning Tue, Nov 24, priced at $171 Found 3 days ago

Tue, Nov 17 - Tue, Nov 24 · SDR · FCO · Roundtrip

Select Vueling Airlines flight, departing Thu, Dec 31 from Santander to Rome, returning Sat, Jan 9, priced at $180 Found 3 days ago

Thu, Dec 31 - Sat, Jan 9 · SDR · FCO · Roundtrip

Select Iberia flight, departing Thu, Dec 31 from Santander to Rome, returning Sat, Jan 9, priced at $180 Found 3 days ago

Thu, Dec 31 - Sat, Jan 9 · SDR · FCO · Roundtrip

Select Iberia flight, departing Fri, Jan 15 from Santander to Rome, returning Mon, Jan 18, priced at $184 Found 11 hours ago

Fri, Jan 15 - Mon, Jan 18 · SDR · FCO · Roundtrip

Select Vueling Airlines flight, departing Tue, Nov 17 from Santander to Rome, returning Tue, Nov 24, priced at $186 Found 3 days ago

Tue, Nov 17 - Tue, Nov 24 · SDR · FCO · Roundtrip

Select Iberia flight, departing Sat, Jan 9 from Santander to Rome, returning Mon, Jan 11, priced at $188 Found 3 days ago

Sat, Jan 9 - Mon, Jan 11 · SDR · FCO · Roundtrip

Select British Airways flight, departing Sat, Jan 9 from Santander to Rome, returning Mon, Jan 11, priced at $969 Found 3 days ago

Sat, Jan 9 - Mon, Jan 11 · SDR · FCO · Roundtrip

Book with confidence

Santander to Rome Flights

The cheapest times to fly from Santander to Rome

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Santander to Rome are during the month of December. You can find some of the cheapest flights from Santander to Rome with Expedia's search tool and vast selection of airlines.

The best time to book a flight from Santander to Rome

Sunday is one of the best days to book for cheap flights from Santander to Rome: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

How to find cheap round-trip tickets from Santander to Rome

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Santander to Rome in 2026. You can also book with separate airlines for your outbound and return journeys, from $76 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Santander to Rome flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

You could also save big by booking one of Expedia's vacation packages. Bundling together your Santander to Rome airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

*Terms apply.

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

Travel information

Origin airportSantander
Destination airportCiampino Airport
Distance840 miles away
Roundtrip price$157

Explore a world of travel with Expedia

*Available to One Key members.