$355 Cheap Flights from Indianapolis (IND) to Rome (FCO)

Indianapolis (IND) to Rome (FCO) at a glance

Explore a diverse selection of airlines offering flights from Indianapolis (IND) to Rome (FCO) on this long-haul international route. Compare various options from full-service carriers to find an itinerary that aligns with your budget, schedule, and travel plans as you venture into Rome's iconic sights and neighborhoods. Here, you can find essential details for flights departing from Indianapolis International Airport (IND) to Fiumicino - Leonardo da Vinci International Airport (FCO).

• Fastest flight duration: around 10h 30m in-flight, plus roughly 1h 45m layover with one stop
• Route distance: roughly 4,900 miles (7,890 km)
• Flights per week: around 10 departures on average
• Typical fares (one-way): economy tickets often range from $300–$895, depending on seasonality and how far ahead you book

Flights from Indianapolis International Airport (IND) to Fiumicino - Leonardo da Vinci International Airport (FCO)

According to recent traveler bookings, here are the top airlines preferred for flights from Indianapolis to Rome, particularly for one-stop and multi-stop options. Common layover airports include John F. Kennedy International Airport (JFK) with an approximate 2-hour layover, Washington Dulles International Airport (IAD) at around 1 hour and 15 minutes, and Hartsfield-Jackson Atlanta International Airport (ATL) with about a 2-hour layover. This variety allows you to choose the best itinerary by balancing price, overall travel time, and cabin class.

• United: This full-service airline provides both one-stop and multi-stop options, with one-way fares generally between $300 and $1005. United accounts for about 30% of flights on this route, featuring a typical in-flight duration of 10 hours and 30 minutes, culminating in a total travel time of approximately 12 hours and 30 minutes.
• Delta: Offering one-stop service, Delta is a full-service airline with one-way fares usually ranging from $345 to $1065. It represents around 19% of departures on this route, with an in-air time of 10 hours and 30 minutes and a total journey duration of roughly 12 hours and 30 minutes, including any layover.
• American Airlines: As a full-service carrier, American Airlines provides both one-stop and multi-stop services, with one-way fares typically costing between $325 and $755. It makes up nearly 18% of flights on this route, featuring a standard in-flight time of 10 hours and 30 minutes and a total travel time of about 12 hours and 30 minutes.
• ITA Airways: This full-service airline offers one-stop flights, with one-way ticket prices usually between $300 and $770. ITA Airways accounts for approximately 8% of departures on this route, with an in-flight duration of 10 hours and 30 minutes, leading to a total journey time of around 12 hours and 30 minutes, factoring in the layover.
• Aer Lingus: Another full-service carrier, Aer Lingus provides one-stop service, with one-way fares typically falling between $370 and $625. This airline covers about 6% of flights on this route, featuring an in-flight time of 10 hours and 30 minutes and a total travel time of approximately 12 hours and 30 minutes, including layover considerations.

Best time to fly from Indianapolis (IND) to Rome (FCO)

The most popular months for travelers flying from Indianapolis to Rome are March, May, and July, when peak temperatures in Rome reach up to 79.3°F in July. If you prefer quieter travel, consider January, the least busy and relatively cheaper time to visit with fewer crowds and temperatures around 46.9°F. For better deals, February usually offers the lowest average one-way fare around $400. Flight availability peaks in March, May, and June, with approximately 11 flights per week, making it easier to find convenient departure times.

• Cheapest time to fly: February usually offers good deals with average one-way fare around $400, roughly 27% cheaper than the yearly average.
• Another budget-friendly time to fly: January typically offers an average one-way fare of around $415.
• Most flight options: March, May, and June have the highest number of flights from Indianapolis to Rome, with approximately 11 flights per week, giving you more flexibility in scheduling your trip.

*Average one-way fare is based on Expedia flight booking data from January 2025 to April 2026 for the specified route and travel class and may change depending on availability, dates, and demand.

Alternative routes from Indianapolis (IND) to Rome (FCO)

• Indianapolis to Rome (IND-CIA): Ciampino Airport (CIA) is located approximately 18 miles from Fiumicino - Leonardo da Vinci International Airport (FCO).
• Indianapolis to Perugia San Francesco d'Assisi – Umbria Intl. Airport (IND-PEG): Perugia San Francesco d'Assisi – Umbria International Airport (PEG) lies around 91 miles from Fiumicino - Leonardo da Vinci International Airport (FCO).

How to find the best prices for flights from Indianapolis (IND) to Rome (FCO)

Getting some of the best deals on flights from Indianapolis to Rome is all about timing and flexibility. Here are some key tips to help you save:

1. Best times to book and fly: cheaper fares are typically found when booking within two weeks, although most travelers book at least two months in advance. Afternoon departures, between 12 p.m. and 6 p.m., tend to offer lower prices and are also the most popular flight times. Additionally, flying on Tuesday generally results in cheaper prices, while Friday is the most popular travel day.
2. Set up price alerts: stay updated on price changes by using Expedia's Price Tracker. Receive alerts when fares drop for your selected route.
3. Bundle and save: bundle your flight and hotel to save on Expedia, or unlock a hotel deal after booking your flight.*
4. Compare flight options: use Expedia's search tool to compare airlines, routes, direct vs. non-direct flights, and flight times. You can also sort by price to find the most affordable options.
5. Stay flexible with dates: being open to different travel days can sometimes help you find better prices on flights and hotels.
6. Think about luggage: nowadays, it's important to check the airline's baggage policies to find the best value. That may be paying for an additional carry-on bag or booking a ticket with checked luggage included. Either way, double-check your allowance before confirming your booking to avoid excess baggage fees at the airport.

*Members only. Savings vary and are not available on all bundles. Select hotels.

Arriving at Fiumicino - Leonardo da Vinci International Airport from Indianapolis International Airport

Rome welcomes travelers from Indianapolis with a range of transport options based on price, convenience, and proximity. Rome city center is approximately a 25-minute drive (covering about 19 miles) from Fiumicino - Leonardo da Vinci International Airport, depending on traffic. Here's how to reach Rome efficiently:

• Hotel transfer: Transfers offer a convenient way to reach your hotel in Rome, with private rides that can be arranged in advance.
• Car rental: Renting a car from Fiumicino - Leonardo da Vinci International Airport is a great option if you plan to explore and sightsee beyond the city. Browse cheap car rentals at Fiumicino - Leonardo da Vinci International Airport on Expedia.
• Taxi/ride-hailing: Taxis and ride-hailing services may be available from designated pickup areas outside the terminal, check locally on arrival.
• Public transportation: From Fiumicino - Leonardo da Vinci International Airport, Fiumicino Airport Station (a train station) is just 0.2 miles away on foot, providing easy access to train services. Meanwhile, Rome-da Vinci/Fiumicino Seaport (a seaport) is located about 0.4 miles away by car, and Stella Polare Station (a metro station) is approximately 5.8 miles away by car, offering various transport options for travelers.

Indianapolis to Rome Flights

The cheapest times to fly from Indianapolis to Rome

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Indianapolis to Rome are during the month of February. You can find some of the cheapest flights from Indianapolis to Rome with Expedia's search tool and vast selection of airlines.

The best time to book a flight from Indianapolis to Rome

Sunday is one of the best days to book for cheap flights from Indianapolis to Rome: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

How to find cheap round-trip tickets from Indianapolis to Rome

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Indianapolis to Rome in 2026. You can also book with separate airlines for your outbound and return journeys, from $355 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Indianapolis to Rome flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

You could also save big by booking one of Expedia's vacation packages. Bundling together your Indianapolis to Rome airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

*Terms apply.

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.