$61 Cheap Flights from St. Louis (STL) to Myrtle Beach (MYR)

View $61 flight on Sun, Sep 21, 2025Opens in a new window

Popular airlines from St. Louis Lambert Intl. Airport (STL) to Myrtle Beach Intl. Airport (MYR)

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Cheap Flights from St. Louis to Myrtle Beach (STL-MYR)

Prices were available within the past 7 days and start at $61 for one-way flights and $145 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Sat, Aug 9 - Thu, Aug 14
STL
St. Louis
MYR
Myrtle Beach
$145 Roundtrip, just found
$145
Roundtrip
just found
Select American Airlines flight, departing Sat, Aug 9 from St. Louis to Myrtle Beach, returning Thu, Aug 14, priced at $145 just found
Spirit Airlines
Sun, Oct 5 - Thu, Oct 9
STL
St. Louis
MYR
Myrtle Beach
$152 Roundtrip, found 3 hours ago
$152
Roundtrip
found 3 hours ago
Select Spirit Airlines flight, departing Sun, Oct 5 from St. Louis to Myrtle Beach, returning Thu, Oct 9, priced at $152 found 3 hours ago
American Airlines
Mon, Aug 11 - Thu, Aug 14
STL
St. Louis
MYR
Myrtle Beach
$161 Roundtrip, found 14 hours ago
$161
Roundtrip
found 14 hours ago
Select American Airlines flight, departing Mon, Aug 11 from St. Louis to Myrtle Beach, returning Thu, Aug 14, priced at $161 found 14 hours ago
American Airlines
Sat, Aug 9 - Thu, Aug 14
STL
St. Louis
MYR
Myrtle Beach
$162 Roundtrip, just found
$162
Roundtrip
just found
Select American Airlines flight, departing Sat, Aug 9 from St. Louis to Myrtle Beach, returning Thu, Aug 14, priced at $162 just found
Spirit Airlines
Mon, Aug 11 - Thu, Aug 14
STL
St. Louis
MYR
Myrtle Beach
$162 Roundtrip, found 14 hours ago
$162
Roundtrip
found 14 hours ago
Select Spirit Airlines flight, departing Mon, Aug 11 from St. Louis to Myrtle Beach, returning Thu, Aug 14, priced at $162 found 14 hours ago
American Airlines
Thu, Aug 7 - Sun, Aug 10
STL
St. Louis
MYR
Myrtle Beach
$166 Roundtrip, found 1 hour ago
$166
Roundtrip
found 1 hour ago
Select American Airlines flight, departing Thu, Aug 7 from St. Louis to Myrtle Beach, returning Sun, Aug 10, priced at $166 found 1 hour ago
Southwest Airlines
Thu, Aug 14 - Fri, Aug 15
STL
St. Louis
MYR
Myrtle Beach
$166 Roundtrip, found 1 day ago
$166
Roundtrip
found 1 day ago
Select Southwest Airlines flight, departing Thu, Aug 14 from St. Louis to Myrtle Beach, returning Fri, Aug 15, priced at $166 found 1 day ago
Spirit Airlines
Mon, Jul 14 - Thu, Jul 17
STL
St. Louis
MYR
Myrtle Beach
$169 Roundtrip, found 1 day ago
$169
Roundtrip
found 1 day ago
Select Spirit Airlines flight, departing Mon, Jul 14 from St. Louis to Myrtle Beach, returning Thu, Jul 17, priced at $169 found 1 day ago
Delta
Thu, Aug 7 - Tue, Aug 12
STL
St. Louis
MYR
Myrtle Beach
$207 Roundtrip, found 1 hour ago
$207
Roundtrip
found 1 hour ago
Select Delta flight, departing Thu, Aug 7 from St. Louis to Myrtle Beach, returning Tue, Aug 12, priced at $207 found 1 hour ago
United
Wed, Jul 16 - Sat, Jul 19
STL
St. Louis
MYR
Myrtle Beach
$287 Roundtrip, found 5 hours ago
$287
Roundtrip
found 5 hours ago
Select United flight, departing Wed, Jul 16 from St. Louis to Myrtle Beach, returning Sat, Jul 19, priced at $287 found 5 hours ago

Alternative airports near Myrtle Beach

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Myrtle Beach Intl. Airport MYR. Cheapest and Closest option available. Average driving time to city center is 6 minutes. Flights from $222
MYR
Myrtle Beach Intl. Airport
CheapestClosest
Average driving time to city center6 min
Flights from $222
Flights from St. Louis (STL) to Myrtle Beach (MYR)
Origin airport
Lambert-St. Louis Intl.
Destination airport
Myrtle Beach Intl.
Airlines serving
American Airlines, Delta, Southwest Airlines, Spirit Airlines, United
Roundtrip price
$144
Distance
726 mi
Average flight time
1 hour 55 mins

St. Louis to Myrtle Beach Flights

The cheapest times to fly from St. Louis to Myrtle Beach

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from St. Louis to Myrtle Beach are during the month of August. You can find some of the cheapest flights from St. Louis to Myrtle Beach with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from St. Louis to Myrtle Beach

Sunday is one of the best days to book for cheap flights from St. Louis to Myrtle Beach: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from St. Louis to Myrtle Beach

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from St. Louis to Myrtle Beach in 2025. You can also book with separate airlines for your outbound and return journeys, from $61 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap St. Louis to Myrtle Beach flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your St. Louis to Myrtle Beach airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Lambert-St. Louis Intl. Airport (STL) to Myrtle Beach Intl. Airport (MYR) cost?
Snag cheap return tickets starting at $277 from Lambert-St. Louis Intl. Airport (STL) to Myrtle Beach Intl. Airport (MYR). This information is based on the cheapest price found on Expedia for this return journey departing within the next three months. This airfare is for a Southwest Airlines flight leaving STL on June 22 2025 and touching down at MYR. The price was last updated on June 16 2025 and has not changed since.
What is the cheapest month to fly from STL to MYR?
The cheapest flights from STL to MYR are usually during off-peak season, when demand is lower. To save money, avoid flying during public holidays, school breaks and major local events.
What is the cheapest airline that flies from STL to MYR?
Currently, the cheapest airline offering one-way flights from STL to MYR is Southwest Airlines. You can jet off on this route from $139. This fare is based on the lowest price found on Expedia departing within the next three months. The flight takes off from STL on July 13 2025. Prices were last updated on June 16 2025 and have not changed since.
How many flights per day from Lambert-St. Louis Intl. Airport (STL) to Myrtle Beach Intl. Airport (MYR)?
Direct flights from Lambert-St. Louis Intl. Airport (STL) to Myrtle Beach Intl. Airport (MYR) aren't available daily, so you'll have to take a flight with a layover. Explore your options with Expedia's filter tool. Enter your travel details and choose either "1 Stop" or "2+ Stops."
What day of the week has the most flights from STL to MYR?
Friday is typically the busiest day for flights, while Tuesday tends to be the quietest.* Keep in mind that flight schedules can vary depending on various factors, including the time of year and airline.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What airline has the least delays from STL to MYR?
United Airlines has the best performance for on-time direct flights from Lambert-St. Louis Intl. Airport (STL) to Myrtle Beach Intl. Airport (MYR), with an on-time rating of 100%. Use the Expedia App to look up your journey status before you jet off and get immediate updates about any trip changes.
What is the best time to fly from Lambert-St. Louis Intl. Airport (STL) to Myrtle Beach Intl. Airport (MYR)?
To arrive at Myrtle Beach Intl. Airport (MYR) without delays, pick a flight that leaves from Lambert-St. Louis Intl. Airport (STL) before 3 PM. The likelihood of cancellations is 22% higher, on average, for departures after this hour.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Lambert-St. Louis Intl. Airport (STL) to Myrtle Beach Intl. Airport (MYR) last-minute?
Booking your flight from STL to MYR shortly before your trip is typically more expensive. But if there's some wiggle room with your travel dates and times, you could snag a cheap last-minute fare.
Is it cheaper to book a STL to MYR flight and hotel package?
You'll generally save money by booking a STL to MYR flight and hotel package compared to booking separately. In fact, travelers could save hundreds of dollars by bundling with Expedia. And it's simple to manage everything in one place. After choosing your ideal accommodations and flights, you can add extras such as tours, activities and car rentals.
Can I cancel or change the date of my flight from Lambert-St. Louis Intl. Airport (STL) to Myrtle Beach Intl. Airport (MYR)?
In most instances, you're able to cancel or reschedule your STL to MYR flight. However, additional fees may apply, especially if your booking was made over 24 hours ago. Double-check your itinerary for the airline's guidelines and fees on flight changes, or if you need further information, visit our Customer Service portal.

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*Available to One Key members.