$109 Cheap Flights from St. Louis (STL) to Myrtle Beach (MYR)

View $109 flight on Thu, Oct 23, 2025Opens in a new window

Popular airlines from St. Louis Lambert Intl. Airport (STL) to Myrtle Beach Intl. Airport (MYR)

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Cheap Flights from St. Louis to Myrtle Beach (STL-MYR)

Prices were available within the past 7 days and start at $109 for one-way flights and $212 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Spirit Airlines
Thu, Oct 23 - Sat, Oct 25
STL
St. Louis
MYR
Myrtle Beach
$212 Roundtrip, found 21 hours ago
$212
Roundtrip
found 21 hours ago
Select Spirit Airlines flight, departing Thu, Oct 23 from St. Louis to Myrtle Beach, returning Sat, Oct 25, priced at $212 found 21 hours ago
Spirit Airlines
Thu, Oct 30 - Mon, Nov 3
STL
St. Louis
MYR
Myrtle Beach
$256 Roundtrip, found 3 days ago
$256
Roundtrip
found 3 days ago
Select Spirit Airlines flight, departing Thu, Oct 30 from St. Louis to Myrtle Beach, returning Mon, Nov 3, priced at $256 found 3 days ago
Spirit Airlines
Thu, Oct 23 - Mon, Oct 27
STL
St. Louis
MYR
Myrtle Beach
$258 Roundtrip, found 14 hours ago
$258
Roundtrip
found 14 hours ago
Select Spirit Airlines flight, departing Thu, Oct 23 from St. Louis to Myrtle Beach, returning Mon, Oct 27, priced at $258 found 14 hours ago
Delta
Wed, Dec 3 - Tue, Dec 9
STL
St. Louis
MYR
Myrtle Beach
$259 Roundtrip, found 1 hour ago
$259
Roundtrip
found 1 hour ago
Select Delta flight, departing Wed, Dec 3 from St. Louis to Myrtle Beach, returning Tue, Dec 9, priced at $259 found 1 hour ago
Southwest Airlines
Wed, Oct 29 - Tue, Nov 4
STL
St. Louis
MYR
Myrtle Beach
$259 Roundtrip, found 1 day ago
$259
Roundtrip
found 1 day ago
Select Southwest Airlines flight, departing Wed, Oct 29 from St. Louis to Myrtle Beach, returning Tue, Nov 4, priced at $259 found 1 day ago
American Airlines
Wed, Oct 29 - Tue, Nov 4
STL
St. Louis
MYR
Myrtle Beach
$263 Roundtrip, found 1 day ago
$263
Roundtrip
found 1 day ago
Select American Airlines flight, departing Wed, Oct 29 from St. Louis to Myrtle Beach, returning Tue, Nov 4, priced at $263 found 1 day ago
Southwest Airlines
Wed, Oct 29 - Tue, Nov 4
STL
St. Louis
MYR
Myrtle Beach
$264 Roundtrip, found 1 day ago
$264
Roundtrip
found 1 day ago
Select Southwest Airlines flight, departing Wed, Oct 29 from St. Louis to Myrtle Beach, returning Tue, Nov 4, priced at $264 found 1 day ago
Spirit Airlines
Sun, Oct 5 - Sat, Oct 11
STL
St. Louis
MYR
Myrtle Beach
$268 Roundtrip, found 1 day ago
$268
Roundtrip
found 1 day ago
Select Spirit Airlines flight, departing Sun, Oct 5 from St. Louis to Myrtle Beach, returning Sat, Oct 11, priced at $268 found 1 day ago
American Airlines
Thu, Oct 23 - Sat, Oct 25
STL
St. Louis
MYR
Myrtle Beach
$269 Roundtrip, found 21 hours ago
$269
Roundtrip
found 21 hours ago
Select American Airlines flight, departing Thu, Oct 23 from St. Louis to Myrtle Beach, returning Sat, Oct 25, priced at $269 found 21 hours ago
United
Tue, Oct 21 - Tue, Nov 4
STL
St. Louis
MYR
Myrtle Beach
$282 Roundtrip, found 5 days ago
$282
Roundtrip
found 5 days ago
Select United flight, departing Tue, Oct 21 from St. Louis to Myrtle Beach, returning Tue, Nov 4, priced at $282 found 5 days ago

Find the cheapest month to fly from St. Louis (STL) to Myrtle Beach (MYR)

August is typically the cheapest month to fly

From $151 - $396 per traveler.

Alternative airports near Myrtle Beach

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Myrtle Beach Intl. Airport MYR. Cheapest and Closest option available. Average driving time to city center is 6 minutes. Flights from $423
MYR
Myrtle Beach Intl. Airport
CheapestClosest
Average driving time to city center6 min
Flights from $423

Frequently asked questions

How much does a flight from Lambert-St. Louis Intl. Airport (STL) to Myrtle Beach Intl. Airport (MYR) cost?
Secure a cheap one-way flight from $109 or cheap return flight from $212 from Lambert-St. Louis Intl. Airport (STL) to Myrtle Beach Intl. Airport (MYR) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight offers on this route.
What is the cheapest month to fly from Lambert-St. Louis Intl. Airport (STL) to Myrtle Beach Intl. Airport (MYR)?
October is the least expensive month to fly from STL to MYR. Timing your trip outside of the busy season is often the key to scoring lower fares.
What is the cheapest airline that flies from Lambert-St. Louis Intl. Airport (STL) to Myrtle Beach Intl. Airport (MYR)?
Use the filter tool on Expedia to compare airlines and find the cheapest carrier that'll fly you from STL to MYR. Then, sort your results by "Price (lowest to highest)" to snap up a good deal.
How many flights per day from Lambert-St. Louis Intl. Airport (STL) to Myrtle Beach Intl. Airport (MYR)?
Direct flights from Lambert-St. Louis Intl. Airport (STL) to Myrtle Beach Intl. Airport (MYR) aren't available daily, so you'll have to take a flight with a layover. Explore your options with Expedia's filter tool. Enter your travel details and choose either "1 Stop" or "2+ Stops."
What day of the week has the most flights from STL to MYR?
Friday is typically the busiest day for flights, while Tuesday tends to be the quietest.* Keep in mind that flight schedules can vary depending on various factors, including the time of year and airline.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What airline has the least delays from STL to MYR?
United Airlines has the best performance for on-time direct flights from Lambert-St. Louis Intl. Airport (STL) to Myrtle Beach Intl. Airport (MYR), with an on-time rating of 100%. Use the Expedia App to look up your journey status before you jet off and get immediate updates about any trip changes.
What is the best time to fly from Lambert-St. Louis Intl. Airport (STL) to Myrtle Beach Intl. Airport (MYR)?
To arrive at Myrtle Beach Intl. Airport (MYR) without delays, pick a flight that leaves from Lambert-St. Louis Intl. Airport (STL) before 3 PM. The likelihood of cancellations is 22% higher, on average, for departures after this hour.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Lambert-St. Louis Intl. Airport (STL) to Myrtle Beach Intl. Airport (MYR) last-minute?
Booking your flight from STL to MYR shortly before your trip is typically more expensive. But if there's some wiggle room with your travel dates and times, you could snag a cheap last-minute fare.
Is it cheaper to book a STL to MYR flight and hotel package?
You'll generally save money by booking a STL to MYR flight and hotel package compared to booking separately. In fact, travelers could save hundreds of dollars by bundling with Expedia. And it's simple to manage everything in one place. After choosing your ideal accommodations and flights, you can add extras such as tours, activities and car rentals.
Can I cancel or change the date of my flight from Lambert-St. Louis Intl. Airport (STL) to Myrtle Beach Intl. Airport (MYR)?
In most instances, you're able to cancel or reschedule your STL to MYR flight. However, additional fees may apply, especially if your booking was made over 24 hours ago. Double-check your itinerary for the airline's guidelines and fees on flight changes, or if you need further information, visit our Customer Service portal.

Travel information

Travel information

Origin airport
Lambert-St. Louis Intl.
Destination airport
Myrtle Beach Intl.
Airlines serving
American Airlines, Delta, Southwest Airlines, Spirit Airlines, United
Roundtrip price
$211
Distance
726 mi

Book with confidence

Book with confidence

St. Louis to Myrtle Beach Flights

The cheapest times to fly from St. Louis to Myrtle Beach

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from St. Louis to Myrtle Beach are during the month of October. You can find some of the cheapest flights from St. Louis to Myrtle Beach with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from St. Louis to Myrtle Beach

Sunday is one of the best days to book for cheap flights from St. Louis to Myrtle Beach: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from St. Louis to Myrtle Beach

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from St. Louis to Myrtle Beach in 2025. You can also book with separate airlines for your outbound and return journeys, from $109 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap St. Louis to Myrtle Beach flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your St. Louis to Myrtle Beach airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

St. Louis to Myrtle Beach Flights

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*Available to One Key members.