Find 4 Star Hotels in Florida Keys from $212

Start date: Check-in selected.
To Date
End date: Check-out

Check availability on Florida Keys 4 Star Hotels

Compare Florida Keys 4 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

Hawks Cay Resort

4.0 star property
Marathon
8.0 out of 10, Very Good, (1005)
"Enjoyed a few days with the kids gere"
United States
Jessica
$368 nightly
The price is $413
Nov 30 - Dec 1
Total with taxes and fees
Hawks Cay Resort

Amara Cay Resort

4.0 star property
Matecumbe
8.8 out of 10, Excellent, (1255)
"The rooms were clean, staff was friendly and helpful, food was delicious, the property was beautiful and loved how there was connections to the other resorts through van transportation or the Rum runner boat! Would definitely stay again! "
United States
Lucia
$207 nightly
The price is $233
Dec 1 - Dec 2
Total with taxes and fees
Amara Cay Resort

Baker's Cay Resort Key Largo, Curio Collection by Hilton

4.0 star property
Key Largo
8.6 out of 10, Excellent, (1012)
"Beautiful and relaxing stay "
Sweden
Pauline
$319 nightly
The price is $359
Dec 3 - Dec 4
Total with taxes and fees
Baker's Cay Resort Key Largo, Curio Collection by Hilton

Playa Largo Resort & Spa, Autograph Collection

4.5 star property
Rock Harbor
9.0 out of 10, Wonderful, (1003)
"Beautiful location, great views, very clean property, room was great (great bed), friendly staff."
United States
Scott
$288 nightly
The price is $324
Nov 30 - Dec 1
Total with taxes and fees
Playa Largo Resort & Spa, Autograph Collection

Faro Blanco Resort & Yacht Club Marathon, Curio by Hilton

4.0 star property
Marathon
8.8 out of 10, Excellent, (1276)
"Great place to stay, extremely pet friendly for those like me who want to travel with their pets. "
United States
James
$188 nightly
The price is $212
Nov 24 - Nov 25
Total with taxes and fees
Faro Blanco Resort & Yacht Club Marathon, Curio by Hilton

Islander Resort

4.0 star property
Matecumbe
9.2 out of 10, Wonderful, (1005)
"The room and amenities were great and it was quiet.. just what we needed"
United States
Sandra
$328 nightly
The price is $370
Dec 16 - Dec 17
Total with taxes and fees
Islander Resort

Tranquility Bay Beachfront Hotel and Resort

4.0 star property
Marathon
8.8 out of 10, Excellent, (1004)
"We enjoyed our stay"
United States
Kathleen
$297 nightly
The price is $334
Dec 8 - Dec 9
Total with taxes and fees
Tranquility Bay Beachfront Hotel and Resort

La Siesta Resort & Villas

4.0 star property
Matecumbe
8.8 out of 10, Excellent, (1002)
"Excellent stay with great amenities."
United States
Maria
$199 nightly
The price is $224
Dec 2 - Dec 3
Total with taxes and fees
La Siesta Resort & Villas

Villas At Hawks Cay Resort

4.0 star property
Marathon
8.4 out of 10, Very Good, (146)
"great trip. Clean, easy to get around. Good amenities for a family trip. "
United States
Dana J
Villas At Hawks Cay Resort

The Islands of Islamorada

4.0 star property
Matecumbe
9.8 out of 10, Exceptional, (68)
"Great for family vacation with kids. love it"
United States
Dixania
$595 nightly
The price is $670
Nov 18 - Nov 19
Total with taxes and fees
The Islands of Islamorada

Marlin Bay Resort & Marina

4.0 star property
Marathon
Marlin Bay Resort & Marina

The Reef at Marathon, Florida Keys

4.0 star property
Marathon
9.4 out of 10, Exceptional, (8)
"It’s always been my favorite. The villas fit all my needs. Fantastic location and friendly staff."
United States
Michelle
The Reef at Marathon, Florida Keys

The Caribbean Resort Coconut Palm North

4.0 star property
Matecumbe
The Caribbean Resort Coconut Palm North
Save an average of 15% on thousands of hotels when you're signed in

Explore similar 5-star hotels

Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in Florida Keys.
Still don't see what you're looking for?
See all properties in Florida Keys.
You can also use these popular filters to refine your search.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Florida Keys

Snorkel crystal-clear waters teeming with colorful fish, then feast on fresh-caught lobster at a laid-back waterfront shack. Drive the scenic Overseas Highway, stopping at Key West's Ernest Hemingway Home and Dry Tortugas National Park for island adventures.

Higgs Beach showing a sandy beach and tropical scenes as well as a large group of people

Top Florida Keys Hotel Reviews

Find out more about Florida Keys

You'll see that you are in fine company with a visit to Florida Keys. Vacationers similar to you have made it one of our top most visited locals the past two years. However, "location, location, location" applies to more than just your vacation destination. When you want to make your next vacation extra special, it's all about where you start each new day.

Properties as Gorgeous as Florida Keys

Florida Keys saw thousands of tourists in 2016, and Expedia's comment section boast comments that highlight how fabulous these properties are. When you book a 4-star hotel you can breathe easy knowing that these properties aim to exceed your needs. You'll never have to search for to sustain your exercise routine, an energizing swim, or nice dinner during your stay, thanks to all that these hotels provide. They aim to make their facilities and grounds pleasing from the instant you step onto the property and with every step across their floors. Florida Keys has dozens of wonderful lodgings that make for the ideal holiday.

Rooms have been fashioned to keep you as comfortable as possible, with amenities like premium bedding, designer bathroom products, and in-room tea or coffee. So, sit back and decompress. Moreover, if you find that you're need of something else, you can trust the staff will do their best to ensure you continue to be pleased during your stay there. These accommodations are so lovely that you'll regret the day you have to return home.

Book a 4-Star Hotel in Florida Keys Today!

A trip to Florida Keys should be one that you'll recollect for years to come, and booking a 4-star hotel can help create memories that are fabulous. Book a 4-star hotel in Florida Keys soon, because several other people are too.

Frequently asked questions

What are the best 4-star hotels in Florida Keys?
If your Florida Keys adventure is in Key Largo, stay at Playa Largo Resort & Spa, Autograph Collection. With lots of amenities such as a firepit and a pillowtop mattress, it earns top marks from many Expedia travelers. Another sought-after option here is Bakers Cay Resort Key Largo, Curio Collection by Hilton. It's also rated 4 stars and features a steam room and a swimming pool.
How much does it cost to stay in a 4-star hotel in Florida Keys?
With Expedia's filter tool, scoring a terrific deal on a 4-star hotel in Florida Keys just got easier. Start by keying in your chosen travel dates and length of your stay. Then list the results by price and pick a property that best matches your style and budget.

  • Search for the lowest price from $299

What's the difference between 5-star and 4-star hotels in Florida Keys?
If you choose to stay at a 4-star hotel in Florida Keys, you'll typically find plenty of amenities to keep you relaxed, such as a restaurant, pool and gym. You can enjoy top-quality service and upmarket surroundings. Opt for a 5-star hotel and you'll have access to a few more perks — think concierge assistance, on-site spas and indulgent turndown services. You're likely to get more amenities and exclusive services at a 5-star getaway, but both are terrific options for luxury guests.