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Find 4 Star Hotels in Southeast Missouri, MO

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Compare Southeast Missouri 4 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

"This is a beautiful property, and the hosts (Jon and Penny) are wonderful. Jon is a chef who prepares really tasty vegan meals. Highly recommended for a weekend getaway!"

Southeast Missouri Four Star Hotel Information

When you need to book a room with luxurious amazing amenities and the best rates, the 4 star hotels in Southeast Missouri, Missouri are incredible options. Known for their extra perks, first-rate service, and fantastic locations, each of the Southeast Missouri 4 star hotels offers the ultimate experience for globe-trotting travelers. Relax in your expertly designed room. Kick back with around-the-clock room service.

Get a good night’s sleep with the ultra-plush bedding, and freshen up in the morning with designer-inspired body products. It’s all available when you stay at one of the top book a four star hotels in Southeast Missouri. What’s more, thanks to Expedia you might even score a cheap great deal on a 4 star hotel in Southeast Missouri, Missouri, areas near the hottest attractions, so you can plan a sightseeing adventure and take advantage of unbeatable discounts in one fell swoop.

Whether you’re putting together a serene getaway or want to revel in the most vibrant entertainment district, 4 star Southeast Missouri hotels offer everything your heart desires.

Frequently asked questions

How much does it cost to stay in a 4-star hotel in Southeast Missouri?

With Expedia’s sort and search filters, landing a terrific deal on a 4-star hotel in Southeast Missouri just got easier. Start by keying in your chosen travel dates and length of your escape. Then list the results by price and pick a property that best matches your style and budget.

Search for the lowest price

What's the difference between 5-star and 4-star hotels in Southeast Missouri?

Offering an inviting traveler experience and upmarket surroundings, 4-star hotels are a fantastic option for your Southeast Missouri getaway. These kinds of stays generally come with loads of handy amenities that make it a breeze to kick back and relax — think complimentary bathrobes, restaurants and pools. Or enjoy even more lavishness at a 5-star hotel designed to indulge you in high-end perks and amenities. Full-service health clubs, oversized bathrooms and gourmet dining are typically featured at these plush retreats.

Does Southeast Missouri have any 4-star all-inclusive resorts?

Use our “All inclusive” filter to find your next escape in Southeast Missouri where just about everything is taken care of, from your accommodations to your food, entertainment and activities. We can also help you find standard 4-star stays in and around this sought-after destination.

Are there any 4-star casino hotels in Southeast Missouri?

Shuffle between your room and the blackjack table with ease by using our filter tool to find 4-star casino hotels in and around Southeast Missouri. Escaping with someone special? Narrow your search further by selecting amenities with that extra wow-factor, like a hot tub or pool.

What are the top 4-star apartments in Southeast Missouri?

You’ll feel at home at Urban Lofts in Perryville, Southeast Missouri. Our 4-star apartments offer the freedom and convenience to fully immerse yourself in the local atmosphere, while ensuring you have all the necessary comforts for an unforgettable stay.