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Find Business Hotels in Southeast Missouri, MO

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Pick from 50 Southeast Missouri Business Hotels and compare room rates, reviews, and availability. Most hotels are fully refundable.

Holiday Inn Express Hotel & Suites Cape Girardeau I-55, an IHG Hotel
2.5 star property
9.6 out of 10, Exceptional, 1,006 reviews
"Great staff and facilities "
The price is $117
$132 total
includes taxes & fees
Jun 23 - Jun 24
Holiday Inn Express Hotel & Suites Cape Girardeau I-55, an IHG Hotel
Drury Inn & Suites Jackson MO
3.0 star property
9.6 out of 10, Exceptional, 966 reviews
"Indoor pool and hot tub. Breakfast and evening provided."
The price is $108
$114 total
includes taxes & fees
Jun 20 - Jun 21
Drury Inn & Suites Jackson MO
Drury Plaza Hotel Cape Girardeau Conference Center
3.0 star property
9.6 out of 10, Exceptional, 1,006 reviews
"Good for a night!"
The price is $112
$127 total
includes taxes & fees
Jun 23 - Jun 24
Drury Plaza Hotel Cape Girardeau Conference Center
Echo Bluff State Park
2.5 star property
9.6 out of 10, Exceptional, 158 reviews
"This is my second time staying here. Beautiful property, friendly staff and a clean room with comfortable bed"
The price is $209
$221 total
includes taxes & fees
Jun 16 - Jun 17
Echo Bluff State Park
Pear Tree Inn Sikeston
2.5 star property
9.4 out of 10, Exceptional, 1,004 reviews
"Letting me use fitness center at Dturtivant was appreciated. Offering gluten free breakfast options would be helpful. "
The price is $90
$103 total
includes taxes & fees
Jun 23 - Jun 24
Pear Tree Inn Sikeston
Drury Inn & Suites Cape Girardeau
3.0 star property
9.4 out of 10, Exceptional, 789 reviews
"The hotel is located in an area with shopping and restaurants are in walking distance. It is very clean and quiet. "
Drury Inn & Suites Cape Girardeau
Drury Inn & Suites Sikeston, MO
3.0 star property
9.4 out of 10, Exceptional, 1,004 reviews
"Cool place "
The price is $99
$112 total
includes taxes & fees
Jun 23 - Jun 24
Drury Inn & Suites Sikeston, MO
Drury Inn & Suites Hayti Caruthersville
3.0 star property
9.4 out of 10, Exceptional, 1,002 reviews
"This place is a great place to stay!"
The price is $117
$133 total
includes taxes & fees
Jun 23 - Jun 24
Drury Inn & Suites Hayti Caruthersville
Drury Inn & Suites Poplar Bluff
3.0 star property
9.2 out of 10, Wonderful, 720 reviews
"Comfortable beds, nice employees, great selection for dinner and breakfast!"
The price is $112
$127 total
includes taxes & fees
Jul 14 - Jul 15
Drury Inn & Suites Poplar Bluff
Pear Tree Inn Cape Girardeau West
2.5 star property
9.0 out of 10, Wonderful, 1,004 reviews
"When traveling with dogs 🐕 we have to accept the upcharges! 2 dogs $50 a night ouch! Its a clean comfortable room. 2nd floor and tge elevator isnt working. Oh well!"
The price is $64
$72 total
includes taxes & fees
Jun 23 - Jun 24
Pear Tree Inn Cape Girardeau West
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See all available properties in Southeast Missouri
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Southeast Missouri Business Hotels information

 

Business Hotels in Southeast Missouri

50

Highest price
$117
Cheapest price
$56
Number of guest reviews
8,755
Total number of hotels in Southeast Missouri
571

 

Frequently asked questions

How much do business-friendly hotels in Southeast Missouri cost?
Prices for business hotels in Southeast Missouri range between $56 and $117 per night. Whatever your budget, Expedia is here to help you find the ideal space for a successful work trip. This price was available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.
What are the best business-friendly hotels in Southeast Missouri?
There are multiple business-friendly hotels in Southeast Missouri with a total average guest review rating of 8.6, so you’re sure to discover a place that’s right for you. Planning a trip to Cape Girardeau? Hampton Inn Cape Girardeau I 55 East is a top pick with corporate travelers. This 2.5-star option has amenities like a terrace and a swimming pool. Drury Plaza Hotel Cape Girardeau Conference Center is also a business favorite. Make use of a swimming pool and free self parking at this 3-star getaway in Cape Girardeau.
How many business-friendly hotels are there in Southeast Missouri?
Southeast Missouri has 50 business-friendly hotels to pick from. Whether you’re attending a conference or meeting or simply working remotely, these stays have the amenities you need to keep you productive and comfortable.
Are there any family-friendly hotels in Southeast Missouri that are also business friendly?
Yes indeed. Whether you’re seeking a place in Southeast Missouri with a meeting room or a quiet space with a strong WiFi connection, Expedia is here to help. Hampton Inn Cape Girardeau I 55 East in Cape Girardeau is a great choice. This 2.5-star business and family-friendly option comes with conveniences like a swimming pool and complimentary breakfast. Drury Plaza Hotel Cape Girardeau Conference Center is another option in Cape Girardeau where corporate travelers can see to their work with family in tow. Complimentary breakfast and a swimming pool are two of the amenities that await you at this 3-star hotel. You’ll find lots of things to do and see with the family in Cape Girardeau. Cape Splash Family Aquatic Center and Lazy L Safari Park offer a wonderful day out.
Why book your business-friendly hotel in Southeast Missouri with Expedia?
With top amenities like conference rooms, 24-hour front desk support and on-site cafés, our business-friendly hotels come with all you’ll need to settle your important deal — and then unwind! Enter your preferred dates and travel destination and we’ll help you do the rest.
How can I find cheap business-friendly hotels in Southeast Missouri?
Click on the “business friendly” filter, listed just under the “traveler experience” heading, to find cheap business-friendly hotels in Southeast Missouri. Then refine your search by your nightly budget. Opting for a property outside the city center is another easy way to save.
What is there to do in Southeast Missouri near my business-friendly hotel?
The best travel accessory for your Southeast Missouri work trip is an awesome itinerary for when you have some free time! Isle Casino Cape Girardeau, Cape Rock Park and Fort D Historic Site are some of the leading sights if you’re headed to Cape Girardeau. Ste Genevieve also has plenty of superb attractions, such as Sainte Genevieve Winery, Bolduc House Museum and Felix Valle House State Historic Site.

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