Find 5 Star Hotels in Big Pine Key, FL from $209

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Compare Big Pine Key 5 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

Property grounds
Isla Bella Beach Resort & Spa
5.0 star property
9.0 out of 10, Wonderful, (1006)
"Muy bueno "
The price is $319
$422 total
includes taxes & fees
Jun 3 - Jun 4
Isla Bella Beach Resort & Spa

Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Big Pine Key.
Faro Blanco Resort & Yacht Club

Faro Blanco Resort & Yacht Club

1996 Overseas Highway, Marathon, FL
The price is $209 per night from May 27 to May 28
$209
$265 total
includes taxes & fees
May 27 - May 28
8.8/10 Excellent! (1,459 reviews)
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Pamper your every desire on your upcoming sabbatical. After all, you love the finer things in life, both at home and when you book a getaway. You'll join the multitudes of vacationers who have made Big Pine Key so popular in the last year. There's no reason to delay a getaway to Big Pine Key any longer. Furthermore, you'll find that these hotels are kept in fantastic condition and provide a fine place to kick back after your daily adventures. Book one of Expedia's luxurious 5-star hotels in Big Pine Key and get ready to enjoy the getaway of a lifetime. Don't wait any longer!

Get a Great Deal on 5-Star Hotels in Big Pine Key

Don't be afraid to request the best service from your hotel, along with the best conditions. Exceptional service, delicious meals, and attentive guest service are all ready for you. You're sure to find exactly the accommodation you need. Besides that, you'll find that these hotels are kept in fantastic condition and provide a fine place to kick back after your daily adventures. What creature comforts do you want in your lodging? 24-hour room service, so you can order that chocolate soufflé© in the wee hours of the morning? A reflexology treatment that will leave you feeling refreshed and alive? Butler services? No matter what you want on a perfect getaway, you're bound to find it here. Want to see for yourself? Plenty of visitors recommend this location.

But you aren't going to spend your entire vacation in your room, of course. We hear you. From doing a bit of shopping to embracing the great outdoors, you'll never be bored on this retreat. No matter what you end up doing, the 5-star hotels in Big Pine Key are waiting for you to relax after a busy day.

Make Your Escape

The results are in, and Big Pine Key 5-star hotels are the place to be when you book your next vacation. These beautiful hotels are highly rated by the guests who stay in them, and you're about to join their ranks. Expedia can help you land a great deal on accommodation. Don't put off your dream vacation any longer. Choose one of Expedia's Big Pine Key 5-star hotels today and relax in the lap of luxury tomorrow.

Frequently asked questions

How much does it cost to stay in a 5-star hotel in Big Pine Key?
You’ll find a variety of pricing options for a 5-star hotel in Big Pine Key on Expedia. The amount you pay will depend on when you travel, length of your trip and other factors. Compare available properties for your desired dates and use our pricing and other filters to score the perfect high-end stay.

  • Search for the lowest price per night from $209

What makes a hotel 5 stars in Big Pine Key?
Outstanding guest service characterizes every 5-star hotel in Big Pine Key. From the moment you arrive, staff are at your beck and call, whether arranging valet parking or providing in-room massages. Additionally, hotels have to feature upscale amenities to meet the standard for a 5-star rating. These can include luxury bathrobes, saunas or spas, pools, gastronomic restaurants and knowledgeable concierge.
Are there any 5-star all-inclusive resorts in Big Pine Key?
Use Expedia’s filter tool to find a high-end escape in Big Pine Key where everything you need is included in the price. From there, narrow down your results for properties that have a 5-star rating and are listed as “All inclusive.” The most important thing to look forward to at these stays? Pure relaxation and indulgence.
Are there any 5-star vacation rentals in Big Pine Key?
Although there aren’t any 5-star vacation rentals in Big Pine Key on our site, we have a range of stays that promise a fantastic getaway. Discover one that matches your style by checking out our vacation rentals in Big Pine Key.

Recent reviews of Big Pine Key hotels
Expedia verified reviews

Isla Bella Beach Resort & Spa

Isla Bella Beach Resort & Spa

5/5 Excellent
"Muy bueno "
A verified traveler stayed at Isla Bella Beach Resort & Spa
Posted 13 hours ago
Isla Bella Beach Resort & Spa