
Santa Croce Vacations from $589
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Your Santa Croce Vacation
Our Santa Croce vacation packages are a fast and practical way to plan and reserve your next adventure. Uncover the true character of this unique neighborhood without the hassle of having to organize everything yourself. Some top nearby attractions to see during your trip to Santa Croce include Cathedral of Santa Maria del Fiore, Ponte Vecchio and Uffizi Gallery. Expedia can put your plans into action. Book your ultimate Santa Croce vacation now.
The Latest Santa Croce Vacation Packages


Hotel Regency
Reviewed on Jul 4, 2025


Villa Tolomei Hotel & Resort
Reviewed on Nov 25, 2025

Hotel Lungarno - Lungarno Collection
Reviewed on Nov 19, 2025
Where to stay in Santa Croce

Historic Centre of Florence
Lose yourself in the Renaissance charm of Florence’s old town, where masterpieces by Brunelleschi and Giotto line up alongside cafés, gelato shops and trattorias.
Santa Croce Hotel Deals

Plaza Hotel Lucchesi
Clean, comfortable room/beds. Great location. Staff was very, very attentive. Very good breakfast. A special shout out to Concierge Extraordinaire Walter, who helped us out way beyond what I expected! I
Reviewed on Nov 18, 2025

FH55 Grand Hotel Mediterraneo
Everything was great. Thank you
Reviewed on Nov 14, 2025

Hotel Balestri
Lovely hotel.
Reviewed on Nov 26, 2025
Discover the most popular places to visit in Santa Croce

Piazza Santa Croce
Italy’s most famous soccer game takes place here once a year, but the square is better known as a nighttime hangout of choice for young people.

Basilica of Santa Croce
Glorious tombs mark the resting place of Michelangelo, Galileo and many other Italian greats in the largest Franciscan church in the world.

National Central Library of Florence
Find out about the history of Florence when you take a trip to National Central Library of Florence. Discover the area's beautiful sunsets and notable monuments.
Things to do

Skip-the-Line Florence Duomo: Priority-Access Express Guided Tour

Tuscany Experience In Pisa, Siena, San Gimignano & Chianti
























