Seneca Vacations from $157

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The Latest Seneca vacation packages

Price found within the past 48 hours. Click for updated prices.
Comfort Inn & Suites Clemson - University Area

Comfort Inn & Suites Clemson - University Area

2.5 out of 5
Price was $205, price is now $157 per person
$157
per person
Dec 12 - Dec 14
found 4 hours ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Greenville (GSP)
8.2/10 Very Good! (1,005 reviews)
The hotel was amazing with the exception of the front desk clerk. She was rude.

Reviewed on Nov 5, 2025

Hilton Greenville

Hilton Greenville

3.5 out of 5
Price was $216, price is now $158 per person
$158
per person
Dec 12 - Dec 14
found 4 hours ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Greenville (GSP)
8.2/10 Very Good! (1,018 reviews)
Staff is always very friendly and accommodating.

Reviewed on Nov 5, 2025

Best Western Plus Clemson Hotel & Conference Center

Best Western Plus Clemson Hotel & Conference Center

2.5 out of 5
Price was $216, price is now $166 per person
$166
per person
Dec 12 - Dec 14
found 4 hours ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Greenville (GSP)
8.2/10 Very Good! (1,013 reviews)
Breakfast offered plenty of choices.

Reviewed on Oct 28, 2025

Comfort Inn & Suites Greer - Greenville

Comfort Inn & Suites Greer - Greenville

2.5 out of 5
Price was $479, price is now $389 per person
$389
per person
Dec 11 - Dec 15
found 1 day ago
Roundtrip flight included
New York (LGA) to Greenville (GSP)
8.6/10 Excellent! (696 reviews)
Very clean room and very hospitable and helpful staff.

Reviewed on Nov 7, 2025

Home2 Suites by Hilton Greenville Downtown

Home2 Suites by Hilton Greenville Downtown

3 out of 5
Greenville Downtown
Price was $667, price is now $560 per person
$560
per person
Dec 12 - Dec 17
found 1 day ago
Roundtrip flight included
New York (LGA) to Greenville (GSP)
9.2/10 Wonderful! (983 reviews)
Great shopping nearby

Reviewed on Nov 3, 2025

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Where to stay in Seneca

Find the best Seneca areas and neighborhoods for the activities you enjoy most. Learn more about Seneca
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Pine Ridge Point

While Pine Ridge Point isn't home to many top sights, Lake Keowee and Keowee Key Golf Course are some notable places to visit nearby.

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Seneca Hotel Deals

Quality Inn Seneca Clemson Area US-123

Quality Inn Seneca Clemson Area US-123

2.5 out of 5
226 Hi Tech Rd, Seneca, SC
Fully refundableReserve now, pay when you stay
$82 nightly
The price is $89 total per night from Dec 7 to Dec 8
$89 total
Dec 7 - Dec 8
Total with taxes and fees
7.8/10 Good! (655 reviews)
Everything has been very good with staff, the room and the property. Would ask that on the days there is no housekeeping service that the trash and fresh towels would be addressed.

Reviewed on Nov 1, 2025

Quality Inn Seneca Clemson Area US-123
Lakeside Lodge Clemson

Lakeside Lodge Clemson

2.5 out of 5
13500 Clemson Blvd, Seneca, SC
Fully refundableReserve now, pay when you stay
$123 nightly
The price is $135 total per night from Nov 10 to Nov 11
$135 total
Nov 10 - Nov 11
Total with taxes and fees
9/10 Wonderful! (1,001 reviews)
Clean room! The staff was great! Beautiful views!

Reviewed on Nov 4, 2025

Lakeside Lodge Clemson
Days Inn by Wyndham Seneca / Clemson Area

Days Inn by Wyndham Seneca / Clemson Area

2 out of 5
11015 N Radio Station Rd, Seneca, SC
Fully refundableReserve now, pay when you stay
$79 nightly
The price is $87 total per night from Nov 30 to Dec 1
$87 total
Nov 30 - Dec 1
Total with taxes and fees
6.8/10 (710 reviews)
Clean, friendly.. great service and lots to do

Reviewed on Oct 28, 2025

Days Inn by Wyndham Seneca / Clemson Area
See all 1,629 properties in Seneca
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Seneca Vacation Packages

Seneca Essential Information

Language
English
Currency
U.S dollars
Population
8,300
Max Temp Winter
50ºF
Max Temp Summer
90ºF

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Frequently asked questions

How much does a Seneca vacation package cost?
You'll find cheap prices from $157 on Expedia for your Seneca break. However, factors like the season, choice of hotel and length of stay will determine how much your vacation to Seneca costs.
What are the cheapest months to go to Seneca?
You can typically find lower rates and better availability in September, October and December. Browse our cheap Seneca vacation packages and you could land some great off-season discounts.
How many days is enough for Seneca?
Usually, a handful of days is enough to tick off the top attractions during your Seneca vacation. But if you prefer to have more time to rest or go on day tours, consider extending your itinerary.
How to find the best Seneca package deals?
Start your search for a Seneca package deal by entering your destination and travel dates under our "Packages" tab. Then add some filters, like "Guest rating" and "Property type," to tailor the results to your exact style. You can also sort by "Package discount" and browse offers that come with irresistible savings. If you don't find the perfect Seneca package deal right away, simply tweak your dates and search again. Keep in mind that deals are only available for a limited time, so book early and get your Seneca escape underway.
Is it cheaper to book a Seneca vacation as a package?
Expedia vacation packages are designed to give you more bang for your buck. Bundle your hotel, car rental and flight into one great-value price and you could save hundreds of dollars. You'll generally get a better deal than booking each component separately. And you'll still enjoy the freedom to create a personalized Seneca vacation by choosing your preferred type of stay, airline and car class.
When to book a vacation package to Seneca?
If you've got your Seneca travel dates locked in, book as early as you can to grab some fantastic deals. With Expedia, you can typically reserve some flights up to one year ahead of time. Prefer spur-of-the-moment getaways? Our last-minute deals are great for traveling on a whim.
Does Expedia offer Book Now, Pay Later Seneca vacation packages?
Set off on your perfect escape to Seneca with help from our Book Now, Pay Later vacations. There's no need to scrimp and save or wait until your next payday — we've joined forces with online lender Affirm to give you financial flexibility. Our vacation packages with payment plans allow you to spread the total cost over 3, 6 or 12 months. With no hidden charges or late payment fees, you can easily stay on budget and snap up cheap deals before they disappear.

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.