Lake City Vacation Rentals

Vacation Rentals in Lake City

Cheerful home with plenty of privacy and entertainment room.
Fridge, microwave, oven, stovetop
Cheerful home with plenty of privacy and entertainment room.
9.2 out of 10, Wonderful, (11)
"The property was very spacious which is what we needed! The kids enjoyed the den with the pool table and we watched movies in there. The cat was a nice surprise to great us at the door (outside). Overall, it was a lovely stay for overnight."
Cheerful home with plenty of privacy and entertainment room.
Oasis Located in the Heart of a Winery/ Halfway Point for Most Travelers
2 bedrooms, WiFi, bed sheets
Oasis Located in the Heart of a Winery/ Halfway Point for Most Travelers
9.6 out of 10, Exceptional, (24)
"Spacing was nice and the set up of rooms coffee nook and walk in shower plus hot tub. Staff was very kind and helpful and walking areas for pet were great. Enjoyed the wine tasting and outside sitting area too."
The price is $125
$222 total
includes taxes & fees
Jun 8 - Jun 9
Oasis Located in the Heart of a Winery/ Halfway Point for Most Travelers
Quaint Bungalow in Historic Downtown Florence
Smart TV, books
Quaint Bungalow in Historic Downtown Florence
10.0 out of 10, Exceptional, (8)
"Very thoughtful will all of the little extra touches. The house was very comfortable and the pictures of the rooms were very spot on. I would rent the same house again."
Quaint Bungalow in Historic Downtown Florence
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Hickory Haven 3Br Elegant Downtown Hidden Gem
Smart TV, video games, foosball, books
Hickory Haven 3Br Elegant Downtown Hidden Gem
9.8 out of 10, Exceptional, (11)
"Our stay in Florence at this VRBO was simply amazing! Cleanliness was 10/10. Amenities were great! It was fully stocked . Game room was an added plus! It was comfortable and very well decorated and very well put together for the comfort of all who desires a home filled environment. The character of this home was superb! My family and I really enjoyed ourselves! We will definitely choose to stay here again . Host communication was excellent! Check in and out was easy an convenient."
Hickory Haven 3Br Elegant Downtown Hidden Gem
Creekside Country Cottage- minutes away from I-95
Interior
Creekside Country Cottage- minutes away from I-95
10.0 out of 10, Exceptional, (3)
"Quintessential knotty pine cottage directly on the lake shore. A classic, evidencing the effort to make it so!"
The price is $250
$472 total
includes taxes & fees
Jun 10 - Jun 11
Creekside Country Cottage- minutes away from I-95
☑️Cozy Work Friendly Condo in Florence☑️
Microwave, cookware/dishes/utensils
☑️Cozy Work Friendly Condo in Florence☑️
9.2 out of 10, Wonderful, (5)
"Good value for price point. Walkable to grocery store, liquor store, pizza place. Apartment is as shown on ad."
The price is $227
$350 total
includes taxes & fees
Jun 9 - Jun 10
☑️Cozy Work Friendly Condo in Florence☑️
Pineapple House: Historic. Southern Charm. Walk Downtown.
Smart TV
Pineapple House: Historic. Southern Charm. Walk Downtown.
9.4 out of 10, Exceptional, (11)
"Beautiful property that provided the laid back welcoming environment of home allowing us a relaxed visiting of family. We enjoyed the privacy of the residence that a hotel cannot provide. Curious as to what the second floor will be in the future, we stayed on the lower first floor during our stay. The residence was close to our relatives and stores. Hopefully we can use the residence again when we visit our SC family in the future! Thank You!"
Pineapple House: Historic. Southern Charm. Walk Downtown.
Walking distance from one of South Carolina's top Medical centers.
Fridge, microwave, oven, stovetop
Walking distance from one of South Carolina's top Medical centers.
10.0 out of 10, Exceptional, (28)
"Home was just as pictured and perfect for us visiting family close by for the holiday. Contained everything needed and then some! :) Host was resposive, and treats they provided were a nice surprise. Thank you for offering your lovely home! ❤️"
Walking distance from one of South Carolina's top Medical centers.
Family Retreat for vacations, weddings, family reunions and corporate retreats.
Property grounds
Family Retreat for vacations, weddings, family reunions and corporate retreats.
Family Retreat for vacations, weddings, family reunions and corporate retreats.
Florence Home
Fridge, microwave, oven, stovetop
Florence Home
10.0 out of 10, Exceptional, (5)
"Very good condition"
Florence Home
Great Home in the Greater Florence Area
Smart TV
Great Home in the Greater Florence Area
10.0 out of 10, Exceptional, (1)
"everything was good"
Great Home in the Greater Florence Area
Comfy Townhome~ Modern Farmhouse with Full Office!
Fridge, blender, dining tables
Comfy Townhome~ Modern Farmhouse with Full Office!
10.0 out of 10, Exceptional, (2)
"I had a very nice stay in Florence at this property. I was working from home through the week and the office setup was perfect."
Comfy Townhome~ Modern Farmhouse with Full Office!
Take a rest in Florence .Ideal for i95 traveler and Florence Center and Buc-ee's
Fridge, microwave, oven, stovetop
Take a rest in Florence .Ideal for i95 traveler and Florence Center and Buc-ee's
10.0 out of 10, Exceptional, (1)
"Family trip to Florida - this was a stop overnight on the way. Excellent location close to I-95, beautiful home. Quiet neighborhood!"
The price is $189
$286 total
includes taxes & fees
Jun 9 - Jun 10
Take a rest in Florence .Ideal for i95 traveler and Florence Center and Buc-ee's
Camping it is!
Property grounds
Camping it is!
Camping it is!
Luxury stay at 4 bedroom house
Fridge, microwave, oven, stovetop
Luxury stay at 4 bedroom house
9.0 out of 10, Wonderful, (2)
"We went to Florence for a family reunion and wanted a place close by. The house is fine but slightly strange in its decor. It's perfectly fine, safe, and the host responds to questions very quickly,"
Luxury stay at 4 bedroom house
Townhouse in Florence SC closed to MUSC medical center.
Living area
Townhouse in Florence SC closed to MUSC medical center.
Townhouse in Florence SC closed to MUSC medical center.
Stylish 3B/2Ba Condo-Sleeps 6. Close to Florence Center, Shopping & Airport.
Living area
Stylish 3B/2Ba Condo-Sleeps 6. Close to Florence Center, Shopping & Airport.
Stylish 3B/2Ba Condo-Sleeps 6. Close to Florence Center, Shopping & Airport.
Work Friendly House Downtown Florence
Property grounds
Work Friendly House Downtown Florence
Work Friendly House Downtown Florence
Charming 2 bedroom near downtown
Exterior
Charming 2 bedroom near downtown
Charming 2 bedroom near downtown
Don't see what you're looking for?
See all available properties in Lake City
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Lake City Vacation Rental Travel Info

Popular accommodation
Lake City agritourism lodgings
Known landmarks
The Country Club at Lake City and The Bean Market
International airports
Myrtle Beach, SC (MYR-Myrtle Beach Intl.) and Florence, SC (FLO-Florence Regional)

Other types of properties in Lake City you may be interested in

The Inn at the Crossroads
Exterior
The Inn at the Crossroads
2.0 star property
9.4 out of 10, Exceptional, (585)
"We enjoyed our stay at the Inn. We've been coming there for some years now. The only bad I could say is, "Everybody knows about this place now." We can't reserve a year in advance now on some holiday weekends. They are always booked up."
The price is $165
$185 total
includes taxes & fees
Jun 23 - Jun 24
The Inn at the Crossroads
Quality Inn & Suites
Lobby
Quality Inn & Suites
2.5 star property
7.2 out of 10, Good, (131)
"Very clean hotel. Super nice young man checked us in. Grocery store about 3 blocks away. Lots of restaurants around the area. Bed was very comfy. I would stay there again!"
The price is $115
$129 total
includes taxes & fees
Jun 20 - Jun 21
Quality Inn & Suites
Days Inn by Wyndham Lake City
Lobby
Days Inn by Wyndham Lake City
2.0 star property
6.4 out of 10, (217)
"The staff were friendly and helpful. The price was reasonable for an overnight stay. Easy park in front of room."
The price is $111
$125 total
includes taxes & fees
Jun 29 - Jun 30
Days Inn by Wyndham Lake City
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Everything you need to know about Lake City vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Lake City vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Lake City vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Lake City vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Lake City. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Lake City in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $125 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on Lake City rentals

At Expedia, we put the best Lake City vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Lake City rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Lake City vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Lake City. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Frequently asked questions

Can I find a vacation rental in Lake City?

Yes, we offer vacation rentals in Lake City near Moore Farms Botanical Garden, or you can choose a secluded option if you want a relaxing stay. Visitors to Lake City speak positively about the lakeside and restaurants in this destination. Make sure you have time to check out the shopping and parks during your trip.

What are some of the best vacation rentals that Lake City has to offer?

Hickory Haven 3Br Elegant Downtown Hidden Gem: This vacation home rental outside of Lake City is equipped with a selection of games, air-conditioning, and laundry facilities to help you feel comfortable during your stay. It has 3 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family.

What can I see and do in Lake City?

Lions Park and Moore Farms Botanical Garden are a couple of lovely local spots to get outside and enjoy nature. The Country Club at Lake City and The Bean Market are other places to visit while you're in town.

What are vacation rentals like in Lake City?

Vacation rentals are private properties you can stay in for a couple days or more in Lake City. Vacation rentals feature amenities such as WiFi and washers and dryers so your stay will be comfortable. If you're concerned about a clean environment, vacation rentals can offer a sense of seclusion away from public hotel elevators and bustling concierge desks while still allowing you the excitement and enjoyment of travel. You'll also have more space in a vacation rental than in a traditional hotel, which is another reason why a vacation rental is a great choice for family trips or small group gatherings.

Recent reviews of Lake City properties
Expedia verified reviews

Days Inn by Wyndham Florence Near Civic Center

Days Inn by Wyndham Florence Near Civic Center

5/5 Excellent
"This Days Inn is situated and a particularly convenient location! Right next to the mall, movies, and several of the main restaurants in florence! To top it off, they have excellent booking rates through Expedia! Very satisfied."
A verified traveler stayed at Days Inn by Wyndham Florence Near Civic Center
Posted 3 days ago
Days Inn by Wyndham Florence Near Civic Center