Find 4 Star Hotels in Southern Illinois, IL from $116
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Compare Southern Illinois 4 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.
Southern Illinois Four Star Hotel Information
When you need to book a room with luxurious amazing amenities and the best rates, the 4 star hotels in Southern Illinois, Illinois are incredible options. Known for their extra perks, first-rate service, and fantastic locations, each of the Southern Illinois 4 star hotels offers the ultimate experience for globe-trotting travelers. Relax in your expertly designed room. Kick back with around-the-clock room service.
Get a good night’s sleep with the ultra-plush bedding, and freshen up in the morning with designer-inspired body products. It’s all available when you stay at one of the top book a four star hotels in Southern Illinois. What’s more, thanks to Expedia you might even score a cheap great deal on a 4 star hotel in Southern Illinois, Illinois, areas near the hottest attractions, so you can plan a sightseeing adventure and take advantage of unbeatable discounts in one fell swoop.
Whether you’re putting together a serene getaway or want to revel in the most vibrant entertainment district, 4 star Southern Illinois hotels offer everything your heart desires.
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![DoubleTree by Hilton Mt. Vernon](http://images.trvl-media.com/lodging/1000000/10000/5600/5553/5af8e624_y.jpg)
DoubleTree by Hilton Mt. Vernon
Southern Illinois Hotels by Star Rating
Hotels in Southern Illinois Neighborhoods
Stay near popular Southern Illinois attractions
- Shawnee National Forest
- Southern Illinois University
- Harrah's Metropolis
- Lake of Egypt
- Rend Lake
- Garden of the Gods Recreation Area
- Giant City State Park
- O'Fallon Family Sports Park
- Lake Shelbyville
- Carlyle Lake
- World Wide Technology Raceway
- Eastern Illinois University
- Scott Air Force Base
- Cahokia Mounds State Historic Site
- Gateway Conference Center
- Lake Sara
- Superman Statue
- Cave in Rock State Park
- DuQuoin State Fairgrounds
- I-57 Drag Strip
More Hotel Options in Southern Illinois
- Business Hotels (149)
- Casinos (13)
- Cheap Hotels (95)
- Family Hotels (167)
- Golf Hotels (112)
- Historic Hotels (56)
- Hotel Wedding Venues (28)
- Hotels & Resorts for Couples (53)
- Hotels with Air Conditioning (198)
- Hotels with Balconies (13)
- Hotels with Bars (46)
- Hotels with Connecting Rooms (76)
- Hotels with Fireplaces (13)
- Hotels with Free Breakfast (167)
- Hotels with Free Parking (190)
- Hotels with Free Wifi (194)
- Hotels with Hot Tubs (61)
- Hotels with Laundry Facilities (121)
- Hotels with Restaurants (184)
- Hotels with Room Service (21)
- Hotels with Suites (20)
- Hotels with a Gym (100)
- Hotels with a Pool (131)
- Hotels with an Indoor Pool (102)
- Hotels with an Outdoor Pool (119)
- Hotels with smoking rooms (24)
- Luxury Hotels (54)
- Non-Smoking Hotels (95)
- Pet-friendly Hotels (139)
- Resorts & Hotels with Spas (45)
- Romantic Hotels (21)
- Winery Hotels (26)
More Accommodation Types in Southern Illinois
- Vacation Homes in Southern Illinois (274)
- Cabin Rentals in Southern Illinois (120)
- Motels in Southern Illinois (63)
- Apartments in Southern Illinois (59)
- B&B in Southern Illinois (38)
- RV Parks in Southern Illinois (35)
- Cottages in Southern Illinois (29)
- Aparthotels in Southern Illinois (14)
- Farmstay in Southern Illinois (11)
- Condo Rentals in Southern Illinois (7)
- Lodges in Southern Illinois (6)
- Guest Houses in Southern Illinois (3)
- Villas in Southern Illinois (2)
- Chalets in Southern Illinois (1)
- Resorts in Southern Illinois (1)
Explore more hotels
- Suite Dreams Hotel
- Town & Country Inn
- Quality Inn & Suites near St. Louis and I-255
- Drury Inn & Suites St. Louis Collinsville
- Comfort Suites Fairview Heights
- La Quinta Inn & Suites by Wyndham Effingham
- Comfort Suites Mount Vernon
- Unique Suites Hotel
- Country Inn & Suites by Radisson, Effingham, IL
- Harrah's Metropolis Hotel & Casino
- Best Western Marion Hotel
- Red Lion Inn & Suites Pontoon Beach
- La Quinta Inn & Suites by Wyndham Collinsville - St. Louis
- Holiday Inn Express & Suites Mount Vernon, an IHG Hotel
- La Quinta Inn & Suites by Wyndham Pontoon Beach
- La Quinta Inn & Suites by Wyndham O'Fallon, IL - St. Louis
- Best Western Troy Hotel
- Days Inn by Wyndham Collinsville/St. Louis
- Best Western Saluki Inn
- Quality Inn O'Fallon I-64