Search Hotels in Santa Cruz

    Plan, book, stay with confidence
    bex rewards loyalty icon
    Be picky
    Search almost a million properties worldwide
    one key icon
    Treat yourself
    Save instantly and earn perks with One Key
    Learn about One Key
    today icon
    Change your mind
    Book hotels with free cancellation

Top Cities in Santa Cruz

San Lorenzo Cathedral showing a garden
HotelsHotels

Santa Cruz

Santa Cruz

Filter by

Popular filters
Popular filters
Guest rating
Guest rating
Star rating
Payment type
Payment type
Property type
Property type
Neighborhood
Neighborhood
Popular locations
Popular locations
Meal plans available
Meal plans available
Amenities
Amenities
Accessibility
Accessibility
Traveler experience
Traveler experience

Compare 214 hotels in Santa Cruz with room rates, reviews, and availability. Most hotels are fully refundable.

Sports facility
Ibis Santa Cruz DE LA Sierra
3.0 star property
9.8 out of 10, Exceptional, (26)
"I had a great stay at this hotel. It has a good location, within reasonable walking distance to the old town or the restaurant area, though Uber is very easy and cheap. The hotel is good, modern and clean . The ambience is very quiet , I would have liked a more interesting and lively vibe. The room was very spacious and comfortable. The only downside was that my room did not have a mini-fridge. The front desk staff was very helpful and kind. "
The price is $62
$62 total
includes taxes & fees
Jun 4 - Jun 5
Ibis Santa Cruz DE LA Sierra
Front of property
Chairú Eco Hotel
3.5 star property
9.8 out of 10, Exceptional, (11)
"Clean, modern, great staff, breakfast included, good price!"
The price is $50
$50 total
includes taxes & fees
May 27 - May 28
Chairú Eco Hotel
Outdoor pool
El Pueblito Hotel Boutique
3.0 star property
9.8 out of 10, Exceptional, (16)
"El Pueblito is a unique property in Samaipata. Views of the city below are great. All rooms are decorated with different themes related to the buildings of the little town. In the lush gardens peacocks and horses roam freely. The food was just OK. Service was attentive. However, because of its location on the top of the hill, your need a car to move around. After rain, you even might need a 4x4 to reach the hotel. Anyway, I still think is the best place to stay in Samaipata."
The price is $87
$87 total
includes taxes & fees
May 27 - May 28
El Pueblito Hotel Boutique
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free
Outdoor pool, free cabanas
TRYP by Wyndham Santa Cruz
4.0 star property
9.4 out of 10, Exceptional, (77)
"We didn’t arrive until 5:00am and they kept our room available for our late arrival. Staff was A ! Highly recommend and will stay there again."
The price is $63
$63 total
includes taxes & fees
Jun 1 - Jun 2
TRYP by Wyndham Santa Cruz
Breakfast, lunch and dinner served
Hampton by Hilton Santa Cruz/Equipetrol, Bolivia
4.5 star property
9.2 out of 10, Wonderful, (194)
"It’s an awesome place. Location couldn’t be better. Restaurants, cafes, shopping all within walking distance. Neighborhoods to walk around a get to know. Easy transportation to historic downtown and very reasonable cost. "
The price is $89
$89 total
includes taxes & fees
May 25 - May 26
Hampton by Hilton Santa Cruz/Equipetrol, Bolivia
Outdoor pool, open 9:00 AM to 8:00 PM, sun loungers
Premium Suites Deluxe Aparthotel Equipetrol
3.5 star property
9.2 out of 10, Wonderful, (60)
"Great service. Very nice and accommodating staffs "
The price is $53
$53 total
includes taxes & fees
May 23 - May 24
Premium Suites Deluxe Aparthotel Equipetrol
Lobby sitting area
Novotel Santa Cruz De La Sierra
5.0 star property
9.2 out of 10, Wonderful, (63)
"Nice hotel, clean, modern and very comfortable. Nice view. The best option for a solo traveler or business trip in Santa Cruz"
The price is $77
$77 total
includes taxes & fees
Jun 4 - Jun 5
Novotel Santa Cruz De La Sierra
Executive Apartment | Premium bedding, down comforters, pillowtop beds, in-room safe
Fiori Apartment
3.5 star property
9.2 out of 10, Wonderful, (70)
"Really nice and confirtable"
The price is $36
$36 total
includes taxes & fees
May 23 - May 24
Fiori Apartment
Property entrance
Hotel Cortez
3.5 star property
9.0 out of 10, Wonderful, (72)
"Great hotel. The service was outstanding. The room was very clean and nice. It looks just like the pictures. The included breakfast was delicious"
The price is $119
$119 total
includes taxes & fees
May 23 - May 24
Hotel Cortez
Massages
Swissôtel Santa Cruz De La Sierra
4.5 star property
9.0 out of 10, Wonderful, (41)
"Good"
The price is $94
$94 total
includes taxes & fees
May 29 - May 30
Swissôtel Santa Cruz De La Sierra
2 outdoor pools
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
3.5 star property
8.8 out of 10, Excellent, (284)
"Hotel is great. Service is better. Rooms by the pool, which should be the centerpiece of the property, are a bit dated. Bed was just ok. Comfortable enough but not great. "
The price is $139
$139 total
includes taxes & fees
May 31 - Jun 1
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
Property amenity
Marriott Santa Cruz de la Sierra Hotel
5.0 star property
8.8 out of 10, Excellent, (147)
"Clean comfortable room and beds. Nice fitness center. Small pool and hot tub could be hotter. Munimal vegan options at restaurant but lots of other places nearby. "
The price is $110
$110 total
includes taxes & fees
Jun 7 - Jun 8
Marriott Santa Cruz de la Sierra Hotel
Front of property
Camino Real Hotel
4.5 star property
8.8 out of 10, Excellent, (327)
"Excelente hotel, muy confortable. Lo único malo es que no se puede desayunar con la ropa que saldrás al trabajo, hay mucho olor a comida en el restaurante y se queda en la ropa."
The price is $116
$116 total
includes taxes & fees
May 27 - May 28
Camino Real Hotel
Courtyard
Apart Hotel Buen Retiro
2.5 star property
8.8 out of 10, Excellent, (48)
"Great"
The price is $40
$40 total
includes taxes & fees
May 23 - May 24
Apart Hotel Buen Retiro
Terrace/patio
Apart Hotel Toborochi
3.0 star property
8.8 out of 10, Excellent, (58)
"Great pool and rooms, bad service and staff "
The price is $60
$60 total
includes taxes & fees
May 23 - May 24
Apart Hotel Toborochi
Reception
HOTEL OSHO
3.5 star property
8.6 out of 10, Excellent, (18)
"I like his service "
The price is $75
$75 total
includes taxes & fees
Jun 4 - Jun 5
HOTEL OSHO
Outdoor pool
Sun Hotel
3.5 star property
8.4 out of 10, Very Good, (244)
"This property is great if you need proximity to the airport. I arrived on a late evening flight and was flying back out in the morning. The shuttle service was very accommodating, waiting for me while I got my tourist visa. "
The price is $122
$122 total
includes taxes & fees
May 23 - May 24
Sun Hotel
Front of property - evening/night
Hotel LP Equipetrol
3.5 star property
8.2 out of 10, Very Good, (185)
"The property is good. My only problem was the wifi which in my room was very poor and in other areas very slow."
The price is $55
$55 total
includes taxes & fees
May 24 - May 25
Hotel LP Equipetrol
Room
Delfines Collection Hotel By Mercure
3.5 star property
8.2 out of 10, Very Good, (20)
"Buena ubicación. Personal amable. Lugar tranquilo. Habitaciones confortables. "
The price is $37
$37 total
includes taxes & fees
May 26 - May 27
Delfines Collection Hotel By Mercure
Outdoor pool, sun loungers
Senses Boutique Hotel
3.5 star property
8.0 out of 10, Very Good, (287)
"Very large and confortable rooms in central location. Breakfast could be better but staff is very friendly and helpful "
Senses Boutique Hotel
Don't see what you're looking for?
See all available properties in Santa Cruz
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Santa Cruz Travel Info

Accommodation
214
Hotels with free breakfast
29
Lowest price
$13
Highest price
$139
International airport
Santa Cruz (VVI-Viru Viru Intl.)
Top attractions
Santa Cruz Zoo, Amboró National Park and San Lorenzo Cathedral
Cities to visit
Colinas del Urubo, Samaipata and San Jose de Chiquitos
Number of reviews
2,192

Frequently asked questions

How much do hotels in Santa Cruz cost?
Prices for Santa Cruz hotels vary depending on the season and other factors, like school holidays and Christmas. You can find cheap options from $13 in a few different ways. Enter your destination and vacation dates and then pick your budget using the “Price per night” filter. You can then narrow your search by choosing your preferred property type and amenities and more.
When is the best time to go to Santa Cruz?
The answer depends on what you want to get out of your Santa Cruz break. If you want to visit in summer, which is between December and February, expect average temperatures of between 72ºF and 88ºF. Santa Cruz has a tropical savanna climate, so bear that in mind when packing.
Are there any luxury hotels in Santa Cruz?
We’ve got some fantastic stays for a lavish retreat in Santa Cruz, Santa Cruz, including Hampton by Hilton Santa Cruz/Equipetrol, Bolivia. Settle in and get access to amenities like concierge services, a garden and complimentary breakfast. Alternatively, pamper yourself at Radisson Hotel Santa Cruz.
What are the top all-inclusive hotels in Santa Cruz?
If you’re seeking a chilled out and worry-free escape, settle in at Prince Hotel. Generally including your meals, food and some recreational activities in the flat upfront price, it’s one of the best picks for an all-inclusive retreat in Santa Cruz.
How can I find cheap hotels in Santa Cruz?
Santa Cruz cheap hotels start at $13 per night. To discover these types of affordable options, use our “Price per night” filter. Like some other tips? Be flexible with your travel dates and book early. Check out our cheap hotels in Santa Cruz page for offers you’ll find difficult to resist.
What are the best hotels in Santa Cruz for families?
Scoring a hotel for you and the kiddos in Santa Cruz is a breeze with our filter tool. Simply check “Family friendly” under the “Traveler experience” heading and see what’s available. If your destination is Santa Cruz, have a look at Cosmopolitano Hotel Boutique. Unwind here while enjoying the use of amenities like complimentary breakfast and a swimming pool. Hampton by Hilton Santa Cruz/Equipetrol, Bolivia is another favorite with families in this exciting city.
What are the top beach hotels in Santa Cruz?
Book one of our hotels with sea views in Santa Cruz and spend your days creating lasting memories along the shore. Kick back in top accommodations such as Las Americas, which comes with amenities like a terrace and a restaurant.
Why should I book my Santa Cruz hotel with Expedia?
Book your Santa Cruz stay with Expedia for price, choice and ease. Also, our One Key™ rewards platform lets you collect OneKeyCash™* on any eligible flights, activities, hotels, car rentals and more. Plus, we offer flexibility should your itinerary change, and if you have any questions or require assistance, our online Help Center is available 24/7. *OneKeyCash disclaimer - OneKeyCash is not redeemable for cash and can only be used on Hotels.com, Expedia and Vrbo.

Recent reviews of Santa Cruz hotels
Expedia verified reviews

TRYP by Wyndham Santa Cruz

TRYP by Wyndham Santa Cruz

5/5 Excellent
"We didn’t arrive until 5:00am and they kept our room available for our late arrival. Staff was A ! Highly recommend and will stay there again."
A verified traveler stayed at TRYP by Wyndham Santa Cruz
Posted 10 days ago
TRYP by Wyndham Santa Cruz