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Independent Southern Illinois Hotel Guide
Some globe-trotters choose hotels based on location, but others book by name. And thanks to Expedia you don’t have to pick. It is why we offer such an expansive range of Independent hotels in Southern Illinois, Illinois. Known for well-appointed rooms and friendly, personalized service, each of the top Independent Southern Illinois hotels guarantees an unparalleled level of comfort and quality.
You’ll find best-in-class amenities like clean rooms and quiet atmospheres, and some Southern Illinois Independent locations may even offer extra little benefits and discounts for frequent travelers.
Recent reviews of Southern Illinois hotelsExpedia verified reviews
![Drury Inn & Suites St. Louis Collinsville](http://images.trvl-media.com/lodging/1000000/50000/42100/42035/fff178d6_y.jpg)
Drury Inn & Suites St. Louis Collinsville
5/5 Excellent
"Great value with friendly and helpful staff…. We enjoyed free cocktails and free dinner….great breakfast as well"
A verified traveler stayed at Drury Inn & Suites St. Louis Collinsville
Posted 23 hours ago
Southern Illinois Hotels by Brand
Hotels in Southern Illinois Neighborhoods
Hotels near popular Southern Illinois Attractions
- Hotels near Shawnee National Forest
- Hotels near Southern Illinois University
- Hotels near Harrah's Metropolis
- Hotels near Lake of Egypt
- Hotels near Rend Lake
- Hotels near Garden of the Gods Recreation Area
- Hotels near Giant City State Park
- Hotels near O'Fallon Family Sports Park
- Hotels near Lake Shelbyville
- Hotels near Carlyle Lake
More Hotel Options in Southern Illinois
- Business Hotels (149)
- Casinos (13)
- Cheap Hotels (95)
- Family Hotels (167)
- Golf Hotels (112)
- Historic Hotels (56)
- Hotel Wedding Venues (28)
- Hotels & Resorts for Couples (53)
- Hotels with Air Conditioning (198)
- Hotels with Balconies (13)
- Hotels with Bars (46)
- Hotels with Connecting Rooms (76)
- Hotels with Fireplaces (13)
- Hotels with Free Breakfast (167)
- Hotels with Free Parking (190)
- Hotels with Free Wifi (194)
- Hotels with Hot Tubs (61)
- Hotels with Laundry Facilities (121)
- Hotels with Restaurants (184)
- Hotels with Room Service (21)
- Hotels with Suites (20)
- Hotels with a Gym (100)
- Hotels with a Pool (131)
- Hotels with an Indoor Pool (102)
- Hotels with an Outdoor Pool (119)
- Hotels with smoking rooms (24)
- Luxury Hotels (54)
- Non-Smoking Hotels (95)
- Pet-friendly Hotels (139)
- Resorts & Hotels with Spas (45)
- Romantic Hotels (21)
- Winery Hotels (26)
More Accommodation Types in Southern Illinois
- Vacation Homes (2,266)
- Apartments (1,998)
- Condo Rentals (330)
- Cabin Rentals (227)
- Motels (227)
- Cottages (186)
- B&B (77)
- Aparthotels (69)
- Guest Houses (62)
- Villas (40)
- RV Parks (39)
- Farmstay (30)
- Lodges (14)
- Resorts (9)
- Inns (8)
- Hostels (4)
- Chalets (3)
- Castles (2)
- Country Houses (1)
- Holiday Park Resorts (1)
- Residences (1)
Explore more hotels
- Suite Dreams Hotel
- Town & Country Inn
- Quality Inn & Suites near St. Louis and I-255
- Drury Inn & Suites St. Louis Collinsville
- Comfort Suites Fairview Heights
- La Quinta Inn & Suites by Wyndham Effingham
- Comfort Suites Mount Vernon
- Unique Suites Hotel
- Country Inn & Suites by Radisson, Effingham, IL
- Harrah's Metropolis Hotel & Casino
- Best Western Marion Hotel
- Red Lion Inn & Suites Pontoon Beach
- La Quinta Inn & Suites by Wyndham Collinsville - St. Louis
- Holiday Inn Express & Suites Mount Vernon, an IHG Hotel
- La Quinta Inn & Suites by Wyndham Pontoon Beach
- La Quinta Inn & Suites by Wyndham O'Fallon, IL - St. Louis
- Best Western Troy Hotel
- Days Inn by Wyndham Collinsville/St. Louis
- Best Western Saluki Inn
- Quality Inn O'Fallon I-64
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