If you'd love to add some extra culture to your escape, put Jewish Museum of Buenos Aires on your must-visit list. Check if there are any guided tours or simply roam around at your leisure.
You're spoiled for sightseeing choice in El Centro. Jewish Museum of Buenos Aires is a good place to start here, but there are lots of other interesting attractions to consider. Obelisco, Colón Theatre, and Casa Rosada are near the museum and will top off your day nicely.