Title: The Best 5 Star Hotels in Andrews, SC | Expedia.com [Andrews Travel Guide](https://expedia.com/Andrews.dx6036)[Hotels in Andrews](https://expedia.com/Andrews-Hotels.d6036.Travel-Guide-Hotels)[Vacation Rentals in Andrews](https://expedia.com/Andrews-Vacation-Rentals.d6036.Travel-Guide-VacationRentals)[Flights to Andrews](https://expedia.com/Cheap-Flights-To-Andrews.d6036.Travel-Guide-Flights)[Car Rentals in Andrews](https://expedia.com/Car-Rentals-In-Andrews.d6036.Car-Rental-Guide)[Andrews Vacation Packages](https://expedia.com/Andrews.d6036.Destination-Travel-Guides) ![Landscape with Black River Nature conservation area in low country South Carolina near city of Andrews](https://images.trvl-media.com/place/6036/582b84fb-4e49-4770-aa90-a8e79271dfc0.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/6036/582b84fb-4e49-4770-aa90-a8e79271dfc0.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Upfront pricing Our total price for your stay includes taxes and fees - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save 10% or more on over 100,000 hotels worldwide with Member Prices [Learn about One Key](https://www.expedia.com/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Andrews 5 Star Hotels Tonight [Mar 22 - Mar 23](https://www.expedia.com/Hotel-Search?regionId=6036&startDate=2026-03-22&endDate=2026-03-23&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Mar 23 - Mar 24](https://www.expedia.com/Hotel-Search?regionId=6036&startDate=2026-03-23&endDate=2026-03-24&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Mar 27 - Mar 29](https://www.expedia.com/Hotel-Search?regionId=6036&startDate=2026-03-27&endDate=2026-03-29&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Apr 3 - Apr 5](https://www.expedia.com/Hotel-Search?regionId=6036&startDate=2026-04-03&endDate=2026-04-05&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.com/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2F5Star-Andrews-Hotels.s50-0-d6036.Travel-Guide-Filter-Hotels)[ Sign up, it's free ](https://expedia.com/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2F5Star-Andrews-Hotels.s50-0-d6036.Travel-Guide-Filter-Hotels) ## Explore similar 4-star hotels Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Andrews. ![Cozy Country Living ](https://images.trvl-media.com/lodging/90000000/89410000/89404900/89404842/4a0bbb94_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Cozy Country Living 124 Stroble family trail Moncks Corner SC [Get rates](https://expedia.com/Hotel-Search?startDate=4%2F5%2F2026&endDate=4%2F6%2F2026&selected=89404842&PinnedHotelID=89404842&HadPinnedHotel=true®ionId=6036) 4.8/10 (3 reviews) [](https://expedia.com/Moncks-Corner-Hotels-Cozy-Country-Living.h89404842.Hotel-Information) ![Pawleys Island Condo at True Blue Golf Resort](https://images.trvl-media.com/lodging/94000000/93540000/93537900/93537886/115b1651_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Pawleys Island Condo at True Blue Golf Resort Pawleys Island SC [Get rates](https://expedia.com/Hotel-Search?startDate=4%2F5%2F2026&endDate=4%2F6%2F2026&selected=93537886&PinnedHotelID=93537886&HadPinnedHotel=true®ionId=6036) 8/10 Very Good! (2 reviews) [](https://expedia.com/Pawleys-Island-Hotels-Pawleys-Island-Condo-At-True-Blue-Golf-Resort.h93537886.Hotel-Information) ![Pawleys Island Condo w/ Screened Porch + Golfing!](https://images.trvl-media.com/lodging/102000000/101510000/101502900/101502866/03343e4f_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Pawleys Island Condo w/ Screened Porch + Golfing! Pawleys Island SC [Get rates](https://expedia.com/Hotel-Search?startDate=4%2F5%2F2026&endDate=4%2F6%2F2026&selected=101502866&PinnedHotelID=101502866&HadPinnedHotel=true®ionId=6036) [](https://expedia.com/Pawleys-Island-Hotels-Pawleys-Island-Condo-W-Screened-Porch-Golfing.h101502866.Hotel-Information) Still don't see what you're looking for? [See all properties in Andrews.](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F23%2F2026&endDate=3%2F24%2F2026®ionId=6036&star=50) You can also use these popular filters to refine your search. [Pool](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F23%2F2026&endDate=3%2F24%2F2026®ionId=6036&star=50&star=50&amenities=POOL)[Spa](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F23%2F2026&endDate=3%2F24%2F2026®ionId=6036&star=50&star=50&amenities=SPA_ON_SITE)[Hot tub](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F23%2F2026&endDate=3%2F24%2F2026®ionId=6036&star=50&star=50&amenities=HOT_TUB)[Breakfast included](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F23%2F2026&endDate=3%2F24%2F2026®ionId=6036&star=50&star=50&amenities=FREE_BREAKFAST)[Waterpark](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F23%2F2026&endDate=3%2F24%2F2026®ionId=6036&star=50&star=50&amenities=WATER_PARK) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Learn more about Andrews Tucked away in South Carolina's coastal region, this small town offers peaceful Southern charm and access to nearby natural attractions. Visitors can enjoy local hospitality at family-owned restaurants while using Andrews as a gateway to explore the Francis Marion National Forest. [See all hotels in Andrews](https://www.expedia.com/Hotel-Search?startDate=2026-04-05&endDate=2026-04-06&adults=2®ionId=6036) ![Landscape with Black River Nature conservation area in low country South Carolina near city of Andrews](https://images.trvl-media.com/place/6036/582b84fb-4e49-4770-aa90-a8e79271dfc0.jpg?impolicy=fcrop&w=900&h=506&p=1&q=high) ## Top Andrews Hotel Reviews ## Find out more about Andrews Why not request total luxury on your jaunt to Andrews? After all, you love the finer things in life, both at home and when you book a getaway. You'll join the multitudes of vacationers who have made Andrews so popular in the last year. There's no reason to delay a getaway to Andrews any longer. You can also expect excellent customer service from these hotels, so get ready to kick back and indulge. Book one of Expedia's luxurious 5-star hotels in Andrews and get ready to enjoy the getaway of a lifetime. You deserve an outstanding getaway. ### 5-Star Hotels in Andrews You'll have a wonderful time at one of these 5-star hotels. Spa treatments, delicious meals, and personalized service are all at your fingertips. You're sure to find exactly the accommodation you need. You can also expect excellent customer service from these hotels, so get ready for a wonderful adventure. How do you want to relax? A mud wrap treatment that will leave you feeling like a million bucks? 24-hour room service, so you can order that chocolate soufflé© in the wee hours of the morning? A full-body massage to help your cares fall away? Want to see for yourself? Explore our listings and pick the perfect accommodation for your needs. But you aren't going to spend your entire vacation in your room, of course. We've got you covered. From doing a bit of shopping to embracing the great outdoors, you'll never be bored on this retreat. No matter what you end up doing, the 5-star hotels in Andrews are waiting for you to rest up after an exciting day. ### Your Getaway Starts Today The results are in, and Andrews 5-star hotels are the place to be when you book your next vacation. If you've been dreaming about a vacation set here, then go ahead and book it. Don't put off your dream vacation any longer -- Expedia can help you land a great deal on accommodation. Decide on one of the 5-star hotels in Andrews today and relax in the lap of luxury when you're ready. ## Frequently asked questions ### How much does it cost to stay in a 5-star hotel in Andrews? > - Search for the lowest price per night ### What makes a hotel 5 stars in Andrews? ### Are there any 5-star all-inclusive resorts in Andrews? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rentals - Other - [Hotels near Andrews Municipal ](https://www.expedia.com/Andrews-Municipal-Airport-Hotels.0-aADR-0.Travel-Guide-Filter-Hotels) - [Jamestown Hotels ](https://www.expedia.com/Jamestown-Hotels.d553248634999321471.Travel-Guide-Hotels) - [4 Star Hotels in Nesmith ](https://www.expedia.com/4Star-Nesmith-Hotels.s40-0-d3000353185.Travel-Guide-Filter-Hotels) - [Nesmith Hotels ](https://www.expedia.com/Nesmith-Hotels.d3000353185.Travel-Guide-Hotels) - [Vacation Homes in Nesmith ](https://www.expedia.com/Nesmith-Private-Vacation-Homes.d3000353185-aaPrivateVacationHomes.Travel-Guide-Accommodation) - 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