Title: Top 10 Hotels in Mayo, SC from $60 - Competitive Prices | Expedia.com [Vacation Rentals in Mayo](https://expedia.com/Mayo-Vacation-Rentals.d553248634999378372.Travel-Guide-VacationRentals)[Car Rentals in Mayo](https://expedia.com/Car-Rentals-In-Mayo.d553248634999378372.Car-Rental-Guide)[Mayo Vacation Packages](https://expedia.com/Mayo.d553248634999378372.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Upfront pricing Our total price for your stay includes taxes and fees - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save 10% or more on over 100,000 hotels worldwide with Member Prices [Learn about One Key](https://www.expedia.com/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Go beyond your typical stay in Mayo Pool [](https://www.expedia.com/Hotel-Search?destination=Mayo%2C+South+Carolina%2C+United+States+of+America®ionId=553248634999378372&latLong=35.084011%2C-81.859825&adults=2&startDate=2026-03-19&d1=2026-03-19&endDate=2026-03-21&d2=2026-03-21&amenities=POOL) Pet friendly [](https://www.expedia.com/Hotel-Search?destination=Mayo%2C+South+Carolina%2C+United+States+of+America®ionId=553248634999378372&latLong=35.084011%2C-81.859825&adults=2&startDate=2026-03-19&d1=2026-03-19&endDate=2026-03-21&d2=2026-03-21&amenities=PETS) Family friendly [](https://www.expedia.com/Hotel-Search?destination=Mayo%2C+South+Carolina%2C+United+States+of+America®ionId=553248634999378372&latLong=35.084011%2C-81.859825&adults=2&startDate=2026-03-19&d1=2026-03-19&endDate=2026-03-21&d2=2026-03-21&travelerType=family_friendly) Cabin [](https://www.expedia.com/Hotel-Search?destination=Mayo%2C+South+Carolina%2C+United+States+of+America®ionId=553248634999378372&latLong=35.084011%2C-81.859825&adults=2&startDate=2026-03-19&d1=2026-03-19&endDate=2026-03-21&d2=2026-03-21&lodging=CABIN) Hot tub [](https://www.expedia.com/Hotel-Search?destination=Mayo%2C+South+Carolina%2C+United+States+of+America®ionId=553248634999378372&latLong=35.084011%2C-81.859825&adults=2&startDate=2026-03-19&d1=2026-03-19&endDate=2026-03-21&d2=2026-03-21&amenities=HOT_TUB) Apart­ment [](https://www.expedia.com/Hotel-Search?destination=Mayo%2C+South+Carolina%2C+United+States+of+America®ionId=553248634999378372&latLong=35.084011%2C-81.859825&adults=2&startDate=2026-03-19&d1=2026-03-19&endDate=2026-03-21&d2=2026-03-21&lodging=APARTMENT) Cottage [](https://www.expedia.com/Hotel-Search?destination=Mayo%2C+South+Carolina%2C+United+States+of+America®ionId=553248634999378372&latLong=35.084011%2C-81.859825&adults=2&startDate=2026-03-19&d1=2026-03-19&endDate=2026-03-21&d2=2026-03-21&lodging=COTTAGE) ## Check prices for these dates Tonight [Mar 5 - Mar 6](https://www.expedia.com/Hotel-Search?regionId=553248634999378372&startDate=2026-03-05&endDate=2026-03-06&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Mar 6 - Mar 7](https://www.expedia.com/Hotel-Search?regionId=553248634999378372&startDate=2026-03-06&endDate=2026-03-07&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Mar 6 - Mar 8](https://www.expedia.com/Hotel-Search?regionId=553248634999378372&startDate=2026-03-06&endDate=2026-03-08&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Mar 13 - Mar 15](https://www.expedia.com/Hotel-Search?regionId=553248634999378372&startDate=2026-03-13&endDate=2026-03-15&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Mayo hotels ![Terrace/patio](https://images.trvl-media.com/lodging/22000000/21600000/21599900/21599844/ce555c3b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/22000000/21600000/21599900/21599844/52525d8c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Studio, 1 King Bed, Non Smoking, Refrigerator & Microwave (Wetbar) | Minibar](https://images.trvl-media.com/lodging/22000000/21600000/21599900/21599844/6276ba27.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/22000000/21600000/21599900/21599844/f51046c4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn & Suites Forest City [](https://www.expedia.com/Forest-City-Hotels-Hampton-Inn-Suites-Forest-City.h21599844.Hotel-Information) Forest City 9.4/10 Exceptional (426 reviews) "Very clean; comfortable; nice decor; friendly, helpful staff; conveniently located." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Brenda $147 nightly $166 total Mar 15 - Mar 16 Total with taxes and fees [](https://www.expedia.com/Forest-City-Hotels-Hampton-Inn-Suites-Forest-City.h21599844.Hotel-Information) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/50000/41900/41874/5f24eb5b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Queen Beds, Non Smoking | Desk, iron/ironing board, free WiFi, alarm clocks](https://images.trvl-media.com/lodging/1000000/50000/41900/41874/322d1c84.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/50000/41900/41874/5403d1fc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Coffee service](https://images.trvl-media.com/lodging/1000000/50000/41900/41874/c78a9998.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Econo Lodge Forest City [](https://www.expedia.com/Forest-City-Hotels-Econo-Lodge.h41874.Hotel-Information) Forest City 6.8/10 (339 reviews) "Good quality of service and clean rooms very safe for family stay." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Yogesh $60 nightly $67 total Apr 4 - Apr 5 Total with taxes and fees [](https://www.expedia.com/Forest-City-Hotels-Econo-Lodge.h41874.Hotel-Information) ![Room, Accessible | Premium bedding, down comforters, desk, blackout drapes](https://images.trvl-media.com/lodging/1000000/90000/80200/80179/0e9956a4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/90000/80200/80179/029a13fb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/90000/80200/80179/2cd653ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool, open 10:00 AM to 10:00 PM, sun loungers](https://images.trvl-media.com/lodging/1000000/90000/80200/80179/62b8a447.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Baymont by Wyndham Forest City [](https://www.expedia.com/Forest-City-Hotels-Baymont-By-Wyndham-Forest-City.h80179.Hotel-Information) Forest City 7.4/10 Good (717 reviews) "Room was great, location was perfect and check in was quick and easy. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Benjamin $71 nightly $81 total Apr 1 - Apr 2 Total with taxes and fees [](https://www.expedia.com/Forest-City-Hotels-Baymont-By-Wyndham-Forest-City.h80179.Hotel-Information) ![Free buffet breakfast](https://images.trvl-media.com/lodging/2000000/1430000/1427800/1427798/182cbcd9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/2000000/1430000/1427800/1427798/4a7d4697.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior entrance](https://images.trvl-media.com/lodging/2000000/1430000/1427800/1427798/01f2674b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/2000000/1430000/1427800/1427798/901c2d58.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express Forest City by IHG [](https://www.expedia.com/Forest-City-Hotels-Holiday-Inn-Express-Forest-City.h1427798.Hotel-Information) Forest City 8.8/10 Excellent (505 reviews) "Fantastic place to stay! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Olivia $151 nightly $171 total Mar 8 - Mar 9 Total with taxes and fees [](https://www.expedia.com/Forest-City-Hotels-Holiday-Inn-Express-Forest-City.h1427798.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/28100/28087/f08daaa9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/30000/28100/28087/d8583276.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/28100/28087/c9a89e89.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Coffee shop](https://images.trvl-media.com/lodging/1000000/30000/28100/28087/a78c349a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Four Points by Sheraton Spartanburg [](https://www.expedia.com/Spartanburg-Hotels-Four-Points-By-Sheraton-Spartanburg.h28087.Hotel-Information) Spartanburg 9.4/10 Exceptional (459 reviews) "Friendly staff, clean rooms, excellent food! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ashley $119 nightly $132 total Mar 15 - Mar 16 Total with taxes and fees [](https://www.expedia.com/Spartanburg-Hotels-Four-Points-By-Sheraton-Spartanburg.h28087.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/22000000/21770000/21768200/21768168/fe2b305f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/22000000/21770000/21768200/21768168/554e5e98.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/22000000/21770000/21768200/21768168/bda34c02.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Full-size fridge, microwave, stovetop, dishwasher](https://images.trvl-media.com/lodging/22000000/21770000/21768200/21768168/fde1795e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Residence Inn by Marriott Spartanburg Westgate [](https://www.expedia.com/Spartanburg-Hotels-Residence-Inn-By-Marriott-Spartanburg-Westgate.h21768168.Hotel-Information) Spartanburg 9.4/10 Exceptional (219 reviews) "The staff is remarkable!! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Chip $151 nightly $168 total Apr 5 - Apr 6 Total with taxes and fees [](https://www.expedia.com/Spartanburg-Hotels-Residence-Inn-By-Marriott-Spartanburg-Westgate.h21768168.Hotel-Information) ![Free daily full breakfast](https://images.trvl-media.com/lodging/3000000/2660000/2654400/2654329/1ada0475.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/3000000/2660000/2654400/2654329/9354fd9f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/3000000/2660000/2654400/2654329/952b2a17.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/3000000/2660000/2654400/2654329/b84eb75d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Suites At WestGate Mall [](https://www.expedia.com/Spartanburg-Hotels-Comfort-Suites-At-WestGate-Mall.h2654329.Hotel-Information) Spartanburg 8.2/10 Very Good (1,003 reviews) "Easy to get in and out" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Thomas $90 nightly $100 total Mar 8 - Mar 9 Total with taxes and fees [](https://www.expedia.com/Spartanburg-Hotels-Comfort-Suites-At-WestGate-Mall.h2654329.Hotel-Information) ![Bar (on property)](https://images.trvl-media.com/lodging/32000000/31360000/31356900/31356806/7bf4f5bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Sports facility](https://images.trvl-media.com/lodging/32000000/31360000/31356900/31356806/62d6498d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/32000000/31360000/31356900/31356806/d9e7f8b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/32000000/31360000/31356900/31356806/8c0b8a30.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilton Garden Inn Spartanburg [](https://www.expedia.com/Spartanburg-Hotels-Hilton-Garden-Inn-Spartanburg.h31356806.Hotel-Information) Spartanburg 9.4/10 Exceptional (502 reviews) "Staff was wonderful " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Denise $115 nightly $127 total Apr 5 - Apr 6 Total with taxes and fees [](https://www.expedia.com/Spartanburg-Hotels-Hilton-Garden-Inn-Spartanburg.h31356806.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/31000000/30470000/30468900/30468866/375f8e51.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/31000000/30470000/30468900/30468866/cb13a9b8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/31000000/30470000/30468900/30468866/a8a35598.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![43-inch flat-screen TV with cable channels, TV](https://images.trvl-media.com/lodging/31000000/30470000/30468900/30468866/c826edfe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Home2 Suites by Hilton Duncan [](https://www.expedia.com/Duncan-Hotels-Home2-Suites-By-Hilton-Duncan.h30468866.Hotel-Information) Duncan 9.4/10 Exceptional (288 reviews) "The Staff was so nice and helpful. The Hotel and rooms were very clean." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Elizabeth $115 nightly $128 total Apr 5 - Apr 6 Total with taxes and fees [](https://www.expedia.com/Duncan-Hotels-Home2-Suites-By-Hilton-Duncan.h30468866.Hotel-Information) ![Restaurant](https://images.trvl-media.com/lodging/1000000/50000/42900/42864/d3799c88.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/50000/42900/42864/8780e584.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/1000000/50000/42900/42864/cab40511.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room amenity](https://images.trvl-media.com/lodging/1000000/50000/42900/42864/24e240e4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Spartanburg Northwest by IHG [](https://www.expedia.com/Spartanburg-Hotels-Holiday-Inn-Spartanburg-Northwest.h42864.Hotel-Information) Spartanburg 7.6/10 Good (833 reviews) "Breakfast was not free but our stay was enjoyable overall. Clean and convenient location for my work trip and staff was really friendly " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jennifer $100 nightly $111 total Mar 21 - Mar 22 Total with taxes and fees [](https://www.expedia.com/Spartanburg-Hotels-Holiday-Inn-Spartanburg-Northwest.h42864.Hotel-Information) ![Free WiFi, bed sheets](https://images.trvl-media.com/lodging/6000000/5240000/5238000/5237949/ddfc6a46.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Combined shower/tub, towels](https://images.trvl-media.com/lodging/6000000/5240000/5238000/5237949/b854acac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/6000000/5240000/5238000/5237949/3b0bd3f9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/6000000/5240000/5238000/5237949/20423eb9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Motel 6 – Spindale, NC – Forest City [](https://www.expedia.com/Forest-City-Hotels-Town-And-Country-Inn-Suites-Spindale.h5237949.Hotel-Information) Spindale 4.4/10 (99 reviews) "To be so close to the holidays and having to work out of town it was a cheap and reasonable place to stay. Staff was friendly, helpful and very accommodating. Will definitely give another try." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Viaton $65 nightly $73 total Mar 7 - Mar 8 Total with taxes and fees [](https://www.expedia.com/Forest-City-Hotels-Town-And-Country-Inn-Suites-Spindale.h5237949.Hotel-Information) ![3 restaurants, breakfast, dinner served; Modern European cuisine](https://images.trvl-media.com/lodging/20000000/19220000/19218500/19218492/b0cbe2b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 restaurants, breakfast, dinner served; Modern European cuisine](https://images.trvl-media.com/lodging/20000000/19220000/19218500/19218492/302e5336.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, free cabanas, pool umbrellas](https://images.trvl-media.com/lodging/20000000/19220000/19218500/19218492/2016aea9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/20000000/19220000/19218500/19218492/1274294b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### AC Hotel by Marriott Spartanburg [](https://www.expedia.com/Spartanburg-Hotels-AC-Hotel-By-Marriott-Spartanburg.h19218492.Hotel-Information) Spartanburg 9.4/10 Exceptional (611 reviews) "Best place to stay in Spartanburg " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Frank $159 nightly $176 total Mar 22 - Mar 23 Total with taxes and fees [](https://www.expedia.com/Spartanburg-Hotels-AC-Hotel-By-Marriott-Spartanburg.h19218492.Hotel-Information) ![Deluxe Room, 2 Queen Bed, Non-Smoking, Kitchenette | Pillowtop beds, individually furnished, desk, laptop workspace](https://images.trvl-media.com/lodging/2000000/1430000/1424600/1424539/6b4205cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/2000000/1430000/1424600/1424539/f128ca38.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1430000/1424600/1424539/000e1c91.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1430000/1424600/1424539/d5df0112.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Suburban Studios Spartanburg - I-26 [](https://www.expedia.com/Spartanburg-Hotels-Suburban-Extended-Stay-Hotel.h1424539.Hotel-Information) Spartanburg 5.8/10 (62 reviews) "Great place to stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tammy $85 nightly $94 total Mar 6 - Mar 7 Total with taxes and fees [](https://www.expedia.com/Spartanburg-Hotels-Suburban-Extended-Stay-Hotel.h1424539.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/3000000/2740000/2733300/2733296/595e9b71.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/3000000/2740000/2733300/2733296/a70212f4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/3000000/2740000/2733300/2733296/daf6d62d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Laundry room](https://images.trvl-media.com/lodging/3000000/2740000/2733300/2733296/3b043c5d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### WoodSpring Suites Spartanburg - Duncan [](https://www.expedia.com/Duncan-Hotels-WoodSpring-Suites-Spartanburg-Duncan-I-85.h2733296.Hotel-Information) Duncan 6.2/10 (251 reviews) "Yes room was clean refrigerator needs a update but everything else was fine " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Janica $64 nightly $72 total Apr 1 - Apr 2 Total with taxes and fees [](https://www.expedia.com/Duncan-Hotels-WoodSpring-Suites-Spartanburg-Duncan-I-85.h2733296.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/39000000/38440000/38436000/38435916/8e69dfe9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/39000000/38440000/38436000/38435916/7152f563.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/39000000/38440000/38436000/38435916/dbc2e960.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/39000000/38440000/38436000/38435916/13c5adfe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn & Suites by Marriott Greenville Spartanburg/Duncan [](https://www.expedia.com/Greenville-Spartanburg-Hotels-Fairfield-Inn-Suites-By-Marriott-Greenville-SpartanburgDuncan.h38435916.Hotel-Information) Duncan 9.4/10 Exceptional (236 reviews) "Staff great..clean..east location" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ian $139 nightly $156 total Apr 5 - Apr 6 Total with taxes and fees [](https://www.expedia.com/Greenville-Spartanburg-Hotels-Fairfield-Inn-Suites-By-Marriott-Greenville-SpartanburgDuncan.h38435916.Hotel-Information) ![Lobby lounge](https://images.trvl-media.com/lodging/1000000/30000/24600/24598/5c3e5e2c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/24600/24598/d8a4a99c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Studio Suite, 1 King Bed with Sofa bed | Hypo-allergenic bedding, desk, iron/ironing board](https://images.trvl-media.com/lodging/1000000/30000/24600/24598/6589b077.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/30000/24600/24598/2d0581c8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Residence Inn by Marriott Spartanburg [](https://www.expedia.com/Spartanburg-Hotels-Residence-Inn-By-Marriott-Spartanburg.h24598.Hotel-Information) Spartanburg 8.0/10 Very Good (470 reviews) "Room was clean, breakfast was terrific and staff helpful." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) William $105 nightly $117 total Apr 4 - Apr 5 Total with taxes and fees [](https://www.expedia.com/Spartanburg-Hotels-Residence-Inn-By-Marriott-Spartanburg.h24598.Hotel-Information) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/2000000/1090000/1088200/1088159/2e33c020.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1090000/1088200/1088159/03ce2fba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/2000000/1090000/1088200/1088159/1aa250fc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/2000000/1090000/1088200/1088159/0a098b85.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn & Suites Spartanburg-I-26-Westgate Mall [](https://www.expedia.com/Spartanburg-Hotels-Hampton-Inn-Suites-Spartanburg-I-26-Westgate-Mall.h1088159.Hotel-Information) Spartanburg 8.6/10 Excellent (997 reviews) "Room was spotless, staff was very friendly. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Anne-Marie $111 nightly $123 total Mar 15 - Mar 16 Total with taxes and fees [](https://www.expedia.com/Spartanburg-Hotels-Hampton-Inn-Suites-Spartanburg-I-26-Westgate-Mall.h1088159.Hotel-Information) ![Free daily on-the-go breakfast](https://images.trvl-media.com/lodging/1000000/910000/900200/900173/97861c81.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, open 8:00 AM to 10:00 PM, sun loungers](https://images.trvl-media.com/lodging/1000000/910000/900200/900173/d3d5e3fb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/910000/900200/900173/54c737da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, blackout drapes, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/910000/900200/900173/744c0880.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express I-26 & Us 29 At Westgate Mall by IHG [](https://www.expedia.com/Spartanburg-Hotels-Holiday-Inn-Express-I-26-Us-29-At-Westgate-Mall.h900173.Hotel-Information) Spartanburg 9.0/10 Wonderful (731 reviews) "Clean room, polite staff, great breakfast." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Donna $116 nightly $129 total Mar 15 - Mar 16 Total with taxes and fees [](https://www.expedia.com/Spartanburg-Hotels-Holiday-Inn-Express-I-26-Us-29-At-Westgate-Mall.h900173.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/106000000/105490000/105488100/105488071/b10e2198.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/106000000/105490000/105488100/105488071/c6761091.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/106000000/105490000/105488100/105488071/ab517c5d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Food and drink](https://images.trvl-media.com/lodging/106000000/105490000/105488100/105488071/f343bb09.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### ECHO Suites Extended Stay by Wyndham Spartanburg [](https://www.expedia.com/Spartanburg-Hotels-Echo-Suites-Spartanburg-Opening-June-2024.h105488071.Hotel-Information) Spartanburg 8.2/10 Very Good (355 reviews) "It's perfect place to stay." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Changyong $91 nightly $103 total Mar 8 - Mar 9 Total with taxes and fees [](https://www.expedia.com/Spartanburg-Hotels-Echo-Suites-Spartanburg-Opening-June-2024.h105488071.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/990000/988800/988782/67f2e81b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 restaurants, breakfast, dinner served; American cuisine](https://images.trvl-media.com/lodging/1000000/990000/988800/988782/ea82fa69.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/990000/988800/988782/e439dee7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/990000/988800/988782/355528af.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Spartanburg Marriott [](https://www.expedia.com/Spartanburg-Hotels-Spartanburg-Marriott.h988782.Hotel-Information) Spartanburg 8.6/10 Excellent (1,001 reviews) "great hotel! Clean and awesome restaurant!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Alicia $118 nightly $131 total Mar 15 - Mar 16 Total with taxes and fees [](https://www.expedia.com/Spartanburg-Hotels-Spartanburg-Marriott.h988782.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.com/Hotel-Search?startDate=2026-03-19&endDate=2026-03-20®ionId=553248634999378372&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-us-ca.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## The Annual Vacation Sale Members save up to 40% on hotels and homes. Plan this year’s big trip and save. [Book now](https://expedia.com/deals?rfrr=HTG_SPRING_PROMO_553248634999378372) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.com/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FMayo-Hotels.d553248634999378372.Travel-Guide-Hotels)[ Sign up, it's free ](https://expedia.com/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FMayo-Hotels.d553248634999378372.Travel-Guide-Hotels) ## Top Mayo Hotel Reviews ![Tru by Hilton Spartanburg](https://images.trvl-media.com/lodging/49000000/48260000/48251500/48251408/b3b1b4a5_y.jpg) ### Tru by Hilton Spartanburg 10/10 Excellent "A quick in and out pit stop stay for my family on a routine long road trip we’ve had for take a few times. This is the second time we’ve stayed here. And it will be our go to stop. Clean, the breakfast is great. Friendly staff. " [](https://expedia.com/Greenville-Spartanburg-Hotels-Tru-By-Hilton-Spartanburg.h48251408.Hotel-Information) ![Sleep Inn Spartanburg Southwest](https://images.trvl-media.com/lodging/1000000/50000/42900/42867/5eb71761_y.jpg) ### Sleep Inn Spartanburg Southwest 10/10 Excellent "Clean rooms" [](https://expedia.com/Spartanburg-Hotels-Sleep-Inn.h42867.Hotel-Information) ![Holiday Inn Express Gaffney by IHG](https://images.trvl-media.com/lodging/72000000/71520000/71515100/71515054/a9c6228a_y.jpg) ### Holiday Inn Express Gaffney by IHG 10/10 Excellent "Considering this is right off the main road it is well kept. Clean, nice staff, standard breakfast." [](https://expedia.com/Gaffney-Hotels-Holiday-Inn-Express-Gaffney.h71515054.Hotel-Information) ![Best Western Spartanburg Northwest](https://images.trvl-media.com/lodging/1000000/20000/19800/19764/d02ac737_y.jpg) ### Best Western Spartanburg Northwest 10/10 Excellent "Very clean, comfortable bed, great breakfast and friendly staff. Overall a great staff and will definitely stay here again." [](https://expedia.com/Spartanburg-Hotels-Best-Western-Spartanburg-Northwest.h19764.Hotel-Information) ![Extended Stay America Premier Suites - Greenville - Spartanburg - I-85](https://images.trvl-media.com/lodging/97000000/96870000/96862800/96862776/f0a08506_y.jpg) ### Extended Stay America Premier Suites - Greenville - Spartanburg - I-85 10/10 Excellent "Clean" [](https://expedia.com/Duncan-Hotels-Extended-Stay-America-Premier-Suites-Greenville-Spartanburg-I-85.h96862776.Hotel-Information) ![Comfort Inn & Suites Spartanburg North](https://images.trvl-media.com/lodging/1000000/890000/888800/888726/d9f6eda3_y.jpg) ### Comfort Inn & Suites Spartanburg North 10/10 Excellent "Yes" [](https://expedia.com/Spartanburg-Hotels-Comfort-Inn-Suites-At-I-85.h888726.Hotel-Information) ![Best Western Plus Spartanburg](https://images.trvl-media.com/lodging/1000000/300000/297100/297091/cfb611f7_y.jpg) ### Best Western Plus Spartanburg 10/10 Excellent "Room was great and so was staff." [](https://expedia.com/Spartanburg-Hotels-Best-Western-Plus-Spartanburg.h297091.Hotel-Information) ![HomeTowne Studios by Red Roof Spartanburg - Asheville Highway](https://images.trvl-media.com/lodging/1000000/50000/41700/41656/9b1f8ee9_y.jpg) ### HomeTowne Studios by Red Roof Spartanburg - Asheville Highway 10/10 Excellent "Room clean Staff helpful Price exceptional " [](https://expedia.com/Spartanburg-Hotels-HomeTowne-Studios-By-Red-Roof-Spartanburg-Asheville-Highway.h41656.Hotel-Information) ![Holiday Inn Express I-26 & Us 29 At Westgate Mall by IHG](https://images.trvl-media.com/lodging/1000000/910000/900200/900173/97861c81_y.jpg) ### Holiday Inn Express I-26 & Us 29 At Westgate Mall by IHG 10/10 Excellent "Room nice! Breakfast lacking!" [](https://expedia.com/Spartanburg-Hotels-Holiday-Inn-Express-I-26-Us-29-At-Westgate-Mall.h900173.Hotel-Information) ## More cheap stays in Mayo ![HomeTowne Studios by Red Roof Spartanburg - Asheville Highway](https://images.trvl-media.com/lodging/1000000/50000/41700/41656/9b1f8ee9_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### HomeTowne Studios by Red Roof Spartanburg - Asheville Highway 130 Mobile Drive Spartanburg SC $54 nightly $60 total Apr 1 - Apr 2 Total with taxes and fees 5.4/10 (466 reviews) [](https://expedia.com/Spartanburg-Hotels-HomeTowne-Studios-By-Red-Roof-Spartanburg-Asheville-Highway.h41656.Hotel-Information) ![Econo Lodge Forest City](https://images.trvl-media.com/lodging/1000000/50000/41900/41874/5f24eb5b_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Econo Lodge Forest City 2600 College Ave Forest City NC $60 nightly $67 total Apr 4 - Apr 5 Total with taxes and fees [](https://expedia.com/Forest-City-Hotels-Econo-Lodge.h41874.Hotel-Information) ![Sleep Inn Spartanburg Southwest](https://images.trvl-media.com/lodging/1000000/50000/42900/42867/5eb71761_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Sleep Inn Spartanburg Southwest 501 South Blackstock Rd Spartanburg SC $62 nightly $69 total Apr 1 - Apr 2 Total with taxes and fees 6/10 (559 reviews) [](https://expedia.com/Spartanburg-Hotels-Sleep-Inn.h42867.Hotel-Information) ![Holiday Inn Express Gaffney by IHG](https://images.trvl-media.com/lodging/72000000/71520000/71515100/71515054/a9c6228a_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Holiday Inn Express Gaffney by IHG 1031 HYATT STREET Gaffney SC $85 nightly $93 total Mar 15 - Mar 16 Total with taxes and fees 8.8/10 Excellent! (450 reviews) [](https://expedia.com/Gaffney-Hotels-Holiday-Inn-Express-Gaffney.h71515054.Hotel-Information) ![Comfort Suites At WestGate Mall](https://images.trvl-media.com/lodging/3000000/2660000/2654400/2654329/1ada0475_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Comfort Suites At WestGate Mall 458 West Blackstock Road Spartanburg SC $90 nightly $100 total Mar 8 - Mar 9 Total with taxes and fees 8.2/10 Very Good! (1,003 reviews) [](https://expedia.com/Spartanburg-Hotels-Comfort-Suites-At-WestGate-Mall.h2654329.Hotel-Information) ![ECHO Suites Extended Stay by Wyndham Spartanburg](https://images.trvl-media.com/lodging/106000000/105490000/105488100/105488071/ab517c5d_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### ECHO Suites Extended Stay by Wyndham Spartanburg 490 W Blackstock Road Spartanburg SC $91 nightly $103 total Mar 8 - Mar 9 Total with taxes and fees 8.2/10 Very Good! (355 reviews) [](https://expedia.com/Spartanburg-Hotels-Echo-Suites-Spartanburg-Opening-June-2024.h105488071.Hotel-Information) ## Hotels in Mayo with star-rating ![3 Star Hotels](https://images.trvl-media.com/lodging/20000000/19690000/19681400/19681371/84fffc75_z.jpg) 3 Star Hotels 32 properties [](https://expedia.com/3Star-Mayo-Hotels.s30-0-d553248634999378372.Travel-Guide-Filter-Hotels) ![2 Star Hotels](https://images.trvl-media.com/lodging/92000000/91830000/91828000/91827910/6717a2ac_z.jpg) 2 Star Hotels 100 properties [](https://expedia.com/2Star-Mayo-Hotels.s20-0-d553248634999378372.Travel-Guide-Filter-Hotels) ## Frequently asked questions ### What is the best area to stay in Mayo? > This central area of Mayo is where you'll find the majority of local businesses, including eateries and shops. It's a compact and walkable district, making it easy to access amenities. The town hall and the local library are also situated here, providing a central point for navigation. > > > For solo travelers or couples, staying in the town center provides easy access to local dining and any community events that might be happening. ### When is the best time to go to Mayo? > During these periods, the weather is pleasantly mild, with comfortable temperatures and lower humidity, making it ideal for outdoor activities and exploring the local area without the intense heat of summer. You'll find many local events and festivals taking place, offering a great way to experience the community's culture. > > > For travelers looking for a relaxed experience, these seasons offer peaceful surroundings. ### Can I cancel my hotel reservation on Expedia? ### How can I save on a Mayo hotel booking with Expedia? > \*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia, Hotels.com and Vrbo. ### How much is the nightly rate at a Mayo hotel? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rentals - [Hotels near Cowpens National Battlefield ](https://www.expedia.com/Cowpens-National-Battlefield-Hotels.0-l6232435-0.Travel-Guide-Filter-Hotels) - [Chesnee Hotels ](https://www.expedia.com/Chesnee-Hotels.d3000353103.Travel-Guide-Hotels) - [Cabin Rentals in Chesnee ](https://www.expedia.com/Chesnee-Cabins.d3000353103-aaCabins.Travel-Guide-Accommodation) - [Red Roof Inn Hotels in Chesnee ](https://www.expedia.com/Chesnee-Hotels-Red-Roof-Inn.0-0-d3000353103--bRedRoofInn.Travel-Guide-Filter-Hotels) - [B&B in Chesnee ](https://www.expedia.com/Chesnee-Bed-And-Breakfast.d3000353103-aaBedAndBreakfast.Travel-Guide-Accommodation) - [Rv Parks in Chesnee ](https://www.expedia.com/Chesnee-RV-Parks.d3000353103-aaRVParks.Travel-Guide-Accommodation) - [5 Star Hotels in Chesnee ](https://www.expedia.com/5Star-Chesnee-Hotels.s50-0-d3000353103.Travel-Guide-Filter-Hotels) - 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