Title: Top 10 Hotels in Mayo, SC from $60 - Competitive Prices | Expedia.com [Vacation Rentals in Mayo](https://expedia.com/Mayo-Vacation-Rentals.d553248634999378372.Travel-Guide-VacationRentals)[Car Rentals in Mayo](https://expedia.com/Car-Rentals-In-Mayo.d553248634999378372.Car-Rental-Guide)[Mayo Vacation Packages](https://expedia.com/Mayo.d553248634999378372.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Upfront pricing Our total price for your stay includes taxes and fees - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save 10% or more on over 100,000 hotels worldwide with Member Prices [Learn about One Key](https://www.expedia.com/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Go beyond your typical stay in Mayo Pool [](https://www.expedia.com/Hotel-Search?destination=Mayo%2C+South+Carolina%2C+United+States+of+America®ionId=553248634999378372&latLong=35.084011%2C-81.859825&adults=2&startDate=2026-03-20&d1=2026-03-20&endDate=2026-03-22&d2=2026-03-22&amenities=POOL) Family friendly [](https://www.expedia.com/Hotel-Search?destination=Mayo%2C+South+Carolina%2C+United+States+of+America®ionId=553248634999378372&latLong=35.084011%2C-81.859825&adults=2&startDate=2026-03-20&d1=2026-03-20&endDate=2026-03-22&d2=2026-03-22&travelerType=family_friendly) Pet friendly [](https://www.expedia.com/Hotel-Search?destination=Mayo%2C+South+Carolina%2C+United+States+of+America®ionId=553248634999378372&latLong=35.084011%2C-81.859825&adults=2&startDate=2026-03-20&d1=2026-03-20&endDate=2026-03-22&d2=2026-03-22&amenities=PETS) Cabin [](https://www.expedia.com/Hotel-Search?destination=Mayo%2C+South+Carolina%2C+United+States+of+America®ionId=553248634999378372&latLong=35.084011%2C-81.859825&adults=2&startDate=2026-03-20&d1=2026-03-20&endDate=2026-03-22&d2=2026-03-22&lodging=CABIN) Hot tub [](https://www.expedia.com/Hotel-Search?destination=Mayo%2C+South+Carolina%2C+United+States+of+America®ionId=553248634999378372&latLong=35.084011%2C-81.859825&adults=2&startDate=2026-03-20&d1=2026-03-20&endDate=2026-03-22&d2=2026-03-22&amenities=HOT_TUB) Apart­ment [](https://www.expedia.com/Hotel-Search?destination=Mayo%2C+South+Carolina%2C+United+States+of+America®ionId=553248634999378372&latLong=35.084011%2C-81.859825&adults=2&startDate=2026-03-20&d1=2026-03-20&endDate=2026-03-22&d2=2026-03-22&lodging=APARTMENT) Cottage [](https://www.expedia.com/Hotel-Search?destination=Mayo%2C+South+Carolina%2C+United+States+of+America®ionId=553248634999378372&latLong=35.084011%2C-81.859825&adults=2&startDate=2026-03-20&d1=2026-03-20&endDate=2026-03-22&d2=2026-03-22&lodging=COTTAGE) ## Check prices for these dates Tonight [Mar 6 - Mar 7](https://www.expedia.com/Hotel-Search?regionId=553248634999378372&startDate=2026-03-06&endDate=2026-03-07&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Mar 7 - Mar 8](https://www.expedia.com/Hotel-Search?regionId=553248634999378372&startDate=2026-03-07&endDate=2026-03-08&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Mar 6 - Mar 8](https://www.expedia.com/Hotel-Search?regionId=553248634999378372&startDate=2026-03-06&endDate=2026-03-08&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Mar 13 - Mar 15](https://www.expedia.com/Hotel-Search?regionId=553248634999378372&startDate=2026-03-13&endDate=2026-03-15&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Mayo hotels ![Terrace/patio](https://images.trvl-media.com/lodging/22000000/21600000/21599900/21599844/ce555c3b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/22000000/21600000/21599900/21599844/f51046c4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Studio, 1 King Bed, Non Smoking, Refrigerator & Microwave (Wetbar) | Minibar](https://images.trvl-media.com/lodging/22000000/21600000/21599900/21599844/6276ba27.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/22000000/21600000/21599900/21599844/b6aa0ccd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn & Suites Forest City [](https://www.expedia.com/Forest-City-Hotels-Hampton-Inn-Suites-Forest-City.h21599844.Hotel-Information) Forest City 9.4/10 Exceptional (426 reviews) "Very clean; comfortable; nice decor; friendly, helpful staff; conveniently located." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Brenda $147 nightly $166 total Mar 15 - Mar 16 Total with taxes and fees [](https://www.expedia.com/Forest-City-Hotels-Hampton-Inn-Suites-Forest-City.h21599844.Hotel-Information) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/50000/41900/41874/5f24eb5b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/50000/41900/41874/5403d1fc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Coffee service](https://images.trvl-media.com/lodging/1000000/50000/41900/41874/c78a9998.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior entrance](https://images.trvl-media.com/lodging/1000000/50000/41900/41874/8a19cae3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Econo Lodge Forest City [](https://www.expedia.com/Forest-City-Hotels-Econo-Lodge.h41874.Hotel-Information) Forest City 6.8/10 (341 reviews) "Good quality of service and clean rooms very safe for family stay." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Yogesh $64 nightly $72 total Mar 21 - Mar 22 Total with taxes and fees [](https://www.expedia.com/Forest-City-Hotels-Econo-Lodge.h41874.Hotel-Information) ![Room, Accessible | Premium bedding, down comforters, desk, blackout drapes](https://images.trvl-media.com/lodging/1000000/90000/80200/80179/0e9956a4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business center](https://images.trvl-media.com/lodging/1000000/90000/80200/80179/d0dba6c4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/90000/80200/80179/029a13fb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool, open 10:00 AM to 10:00 PM, sun loungers](https://images.trvl-media.com/lodging/1000000/90000/80200/80179/62b8a447.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Baymont by Wyndham Forest City [](https://www.expedia.com/Forest-City-Hotels-Baymont-By-Wyndham-Forest-City.h80179.Hotel-Information) Forest City 7.4/10 Good (717 reviews) "Room was great, location was perfect and check in was quick and easy. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Benjamin $71 nightly $81 total Apr 1 - Apr 2 Total with taxes and fees [](https://www.expedia.com/Forest-City-Hotels-Baymont-By-Wyndham-Forest-City.h80179.Hotel-Information) ![Free buffet breakfast](https://images.trvl-media.com/lodging/2000000/1430000/1427800/1427798/182cbcd9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/2000000/1430000/1427800/1427798/4a7d4697.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/2000000/1430000/1427800/1427798/901c2d58.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1430000/1427800/1427798/c45915aa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express Forest City by IHG [](https://www.expedia.com/Forest-City-Hotels-Holiday-Inn-Express-Forest-City.h1427798.Hotel-Information) Forest City 8.8/10 Excellent (505 reviews) "Fantastic place to stay! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Olivia $151 nightly $171 total Mar 10 - Mar 11 Total with taxes and fees [](https://www.expedia.com/Forest-City-Hotels-Holiday-Inn-Express-Forest-City.h1427798.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/28100/28087/f08daaa9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Coffee shop](https://images.trvl-media.com/lodging/1000000/30000/28100/28087/a78c349a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/30000/28100/28087/7636779c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/28100/28087/c9a89e89.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Four Points by Sheraton Spartanburg [](https://www.expedia.com/Spartanburg-Hotels-Four-Points-By-Sheraton-Spartanburg.h28087.Hotel-Information) Spartanburg 9.4/10 Exceptional (459 reviews) "Friendly staff, clean rooms, excellent food! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ashley $119 nightly $132 total Mar 15 - Mar 16 Total with taxes and fees [](https://www.expedia.com/Spartanburg-Hotels-Four-Points-By-Sheraton-Spartanburg.h28087.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/22000000/21770000/21768200/21768168/fe2b305f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool, open 9:00 AM to 7:00 PM, pool umbrellas](https://images.trvl-media.com/lodging/22000000/21770000/21768200/21768168/04e1f5e7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Full-size fridge, microwave, stovetop, dishwasher](https://images.trvl-media.com/lodging/22000000/21770000/21768200/21768168/fde1795e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/22000000/21770000/21768200/21768168/554e5e98.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Residence Inn by Marriott Spartanburg Westgate [](https://www.expedia.com/Spartanburg-Hotels-Residence-Inn-By-Marriott-Spartanburg-Westgate.h21768168.Hotel-Information) Spartanburg 9.4/10 Exceptional (219 reviews) "The staff is remarkable!! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Chip $151 nightly $168 total Apr 5 - Apr 6 Total with taxes and fees [](https://www.expedia.com/Spartanburg-Hotels-Residence-Inn-By-Marriott-Spartanburg-Westgate.h21768168.Hotel-Information) ![Free daily full breakfast](https://images.trvl-media.com/lodging/3000000/2660000/2654400/2654329/1ada0475.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/3000000/2660000/2654400/2654329/952b2a17.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/3000000/2660000/2654400/2654329/36aa2afa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/3000000/2660000/2654400/2654329/9354fd9f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Suites At WestGate Mall [](https://www.expedia.com/Spartanburg-Hotels-Comfort-Suites-At-WestGate-Mall.h2654329.Hotel-Information) Spartanburg 8.2/10 Very Good (1,003 reviews) "Easy to get in and out" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Thomas $90 nightly $100 total Mar 15 - Mar 16 Total with taxes and fees [](https://www.expedia.com/Spartanburg-Hotels-Comfort-Suites-At-WestGate-Mall.h2654329.Hotel-Information) ![Bar (on property)](https://images.trvl-media.com/lodging/32000000/31360000/31356900/31356806/7bf4f5bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/32000000/31360000/31356900/31356806/8c0b8a30.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/32000000/31360000/31356900/31356806/d9e7f8b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/32000000/31360000/31356900/31356806/ff5159b8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilton Garden Inn Spartanburg [](https://www.expedia.com/Spartanburg-Hotels-Hilton-Garden-Inn-Spartanburg.h31356806.Hotel-Information) Spartanburg 9.4/10 Exceptional (502 reviews) "Staff was wonderful " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Denise $115 nightly $127 total Mar 29 - Mar 30 Total with taxes and fees [](https://www.expedia.com/Spartanburg-Hotels-Hilton-Garden-Inn-Spartanburg.h31356806.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/31000000/30470000/30468900/30468866/375f8e51.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/31000000/30470000/30468900/30468866/cb13a9b8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/31000000/30470000/30468900/30468866/a8a35598.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![43-inch flat-screen TV with cable channels, TV](https://images.trvl-media.com/lodging/31000000/30470000/30468900/30468866/c826edfe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Home2 Suites by Hilton Duncan [](https://www.expedia.com/Duncan-Hotels-Home2-Suites-By-Hilton-Duncan.h30468866.Hotel-Information) Duncan 9.4/10 Exceptional (288 reviews) "The Staff was so nice and helpful. The Hotel and rooms were very clean." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Elizabeth $115 nightly $128 total Apr 5 - Apr 6 Total with taxes and fees [](https://www.expedia.com/Duncan-Hotels-Home2-Suites-By-Hilton-Duncan.h30468866.Hotel-Information) ![Restaurant](https://images.trvl-media.com/lodging/1000000/50000/42900/42864/d3799c88.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room amenity](https://images.trvl-media.com/lodging/1000000/50000/42900/42864/24e240e4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/1000000/50000/42900/42864/cab40511.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/50000/42900/42864/8780e584.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Spartanburg Northwest by IHG [](https://www.expedia.com/Spartanburg-Hotels-Holiday-Inn-Spartanburg-Northwest.h42864.Hotel-Information) Spartanburg 7.6/10 Good (833 reviews) "Breakfast was not free but our stay was enjoyable overall. Clean and convenient location for my work trip and staff was really friendly " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jennifer $100 nightly $111 total Apr 4 - Apr 5 Total with taxes and fees [](https://www.expedia.com/Spartanburg-Hotels-Holiday-Inn-Spartanburg-Northwest.h42864.Hotel-Information) ![Free WiFi, bed sheets](https://images.trvl-media.com/lodging/6000000/5240000/5238000/5237949/ddfc6a46.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/6000000/5240000/5238000/5237949/3b0bd3f9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free WiFi, bed sheets](https://images.trvl-media.com/lodging/6000000/5240000/5238000/5237949/1a912277.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Combined shower/tub, towels](https://images.trvl-media.com/lodging/6000000/5240000/5238000/5237949/b854acac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Motel 6 – Spindale, NC – Forest City [](https://www.expedia.com/Forest-City-Hotels-Town-And-Country-Inn-Suites-Spindale.h5237949.Hotel-Information) Spindale 4.4/10 (99 reviews) "To be so close to the holidays and having to work out of town it was a cheap and reasonable place to stay. Staff was friendly, helpful and very accommodating. Will definitely give another try." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Viaton $65 nightly $73 total Mar 7 - Mar 8 Total with taxes and fees [](https://www.expedia.com/Forest-City-Hotels-Town-And-Country-Inn-Suites-Spindale.h5237949.Hotel-Information) ![3 restaurants, breakfast, dinner served; Modern European cuisine](https://images.trvl-media.com/lodging/20000000/19220000/19218500/19218492/b0cbe2b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/20000000/19220000/19218500/19218492/1274294b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/20000000/19220000/19218500/19218492/1ee7acc0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, free cabanas, pool umbrellas](https://images.trvl-media.com/lodging/20000000/19220000/19218500/19218492/2016aea9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### AC Hotel by Marriott Spartanburg [](https://www.expedia.com/Spartanburg-Hotels-AC-Hotel-By-Marriott-Spartanburg.h19218492.Hotel-Information) Spartanburg 9.4/10 Exceptional (611 reviews) "Best place to stay in Spartanburg " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Frank $159 nightly $176 total Mar 22 - Mar 23 Total with taxes and fees [](https://www.expedia.com/Spartanburg-Hotels-AC-Hotel-By-Marriott-Spartanburg.h19218492.Hotel-Information) ![Deluxe Room, 2 Queen Bed, Non-Smoking, Kitchenette | Pillowtop beds, individually furnished, desk, laptop workspace](https://images.trvl-media.com/lodging/2000000/1430000/1424600/1424539/6b4205cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1430000/1424600/1424539/d5df0112.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/2000000/1430000/1424600/1424539/f128ca38.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1430000/1424600/1424539/000e1c91.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Suburban Studios Spartanburg - I-26 [](https://www.expedia.com/Spartanburg-Hotels-Suburban-Extended-Stay-Hotel.h1424539.Hotel-Information) Spartanburg 5.8/10 (62 reviews) "Great place to stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tammy $85 nightly $94 total Mar 7 - Mar 8 Total with taxes and fees [](https://www.expedia.com/Spartanburg-Hotels-Suburban-Extended-Stay-Hotel.h1424539.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/3000000/2740000/2733300/2733296/595e9b71.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Laundry room](https://images.trvl-media.com/lodging/3000000/2740000/2733300/2733296/3b043c5d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/3000000/2740000/2733300/2733296/a9aa6004.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/3000000/2740000/2733300/2733296/daf6d62d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### WoodSpring Suites Spartanburg - Duncan [](https://www.expedia.com/Duncan-Hotels-WoodSpring-Suites-Spartanburg-Duncan-I-85.h2733296.Hotel-Information) Duncan 6.2/10 (251 reviews) "Yes room was clean refrigerator needs a update but everything else was fine " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Janica $64 nightly $72 total Apr 1 - Apr 2 Total with taxes and fees [](https://www.expedia.com/Duncan-Hotels-WoodSpring-Suites-Spartanburg-Duncan-I-85.h2733296.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/39000000/38440000/38436000/38435916/8e69dfe9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/39000000/38440000/38436000/38435916/dbc2e960.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, blackout drapes, iron/ironing board, bed sheets](https://images.trvl-media.com/lodging/39000000/38440000/38436000/38435916/9e08d3a0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/39000000/38440000/38436000/38435916/7152f563.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn & Suites by Marriott Greenville Spartanburg/Duncan [](https://www.expedia.com/Greenville-Spartanburg-Hotels-Fairfield-Inn-Suites-By-Marriott-Greenville-SpartanburgDuncan.h38435916.Hotel-Information) Duncan 9.4/10 Exceptional (236 reviews) "Staff great..clean..east location" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ian $139 nightly $156 total Apr 5 - Apr 6 Total with taxes and fees [](https://www.expedia.com/Greenville-Spartanburg-Hotels-Fairfield-Inn-Suites-By-Marriott-Greenville-SpartanburgDuncan.h38435916.Hotel-Information) ![Lobby lounge](https://images.trvl-media.com/lodging/1000000/30000/24600/24598/5c3e5e2c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/24600/24598/d8a4a99c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hypo-allergenic bedding, desk, iron/ironing board](https://images.trvl-media.com/lodging/1000000/30000/24600/24598/w5400h2699x0y0-814dbab3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/30000/24600/24598/2d0581c8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Residence Inn by Marriott Spartanburg [](https://www.expedia.com/Spartanburg-Hotels-Residence-Inn-By-Marriott-Spartanburg.h24598.Hotel-Information) Spartanburg 8.0/10 Very Good (470 reviews) "Room was clean, breakfast was terrific and staff helpful." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) William $105 nightly $117 total Apr 4 - Apr 5 Total with taxes and fees [](https://www.expedia.com/Spartanburg-Hotels-Residence-Inn-By-Marriott-Spartanburg.h24598.Hotel-Information) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/2000000/1090000/1088200/1088159/2e33c020.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1090000/1088200/1088159/03ce2fba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/2000000/1090000/1088200/1088159/1aa250fc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Courtyard](https://images.trvl-media.com/lodging/2000000/1090000/1088200/1088159/bff8383c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn & Suites Spartanburg-I-26-Westgate Mall [](https://www.expedia.com/Spartanburg-Hotels-Hampton-Inn-Suites-Spartanburg-I-26-Westgate-Mall.h1088159.Hotel-Information) Spartanburg 8.6/10 Excellent (997 reviews) "Room was spotless, staff was very friendly. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Anne-Marie $111 nightly $123 total Mar 15 - Mar 16 Total with taxes and fees [](https://www.expedia.com/Spartanburg-Hotels-Hampton-Inn-Suites-Spartanburg-I-26-Westgate-Mall.h1088159.Hotel-Information) ![Free daily on-the-go breakfast](https://images.trvl-media.com/lodging/1000000/910000/900200/900173/97861c81.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/910000/900200/900173/54c737da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, open 8:00 AM to 10:00 PM, sun loungers](https://images.trvl-media.com/lodging/1000000/910000/900200/900173/d3d5e3fb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Rooftop terrace](https://images.trvl-media.com/lodging/1000000/910000/900200/900173/c3da6451.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express I-26 & Us 29 At Westgate Mall by IHG [](https://www.expedia.com/Spartanburg-Hotels-Holiday-Inn-Express-I-26-Us-29-At-Westgate-Mall.h900173.Hotel-Information) Spartanburg 9.0/10 Wonderful (731 reviews) "Clean room, polite staff, great breakfast." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Donna $116 nightly $129 total Mar 22 - Mar 23 Total with taxes and fees [](https://www.expedia.com/Spartanburg-Hotels-Holiday-Inn-Express-I-26-Us-29-At-Westgate-Mall.h900173.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/106000000/105490000/105488100/105488071/b10e2198.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 Queen Bed, Non Smoking (Mobility, Tub w/Grab Bars) | Egyptian cotton sheets, premium bedding, desk, blackout drapes](https://images.trvl-media.com/lodging/106000000/105490000/105488100/105488071/a675a23e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Food and drink](https://images.trvl-media.com/lodging/106000000/105490000/105488100/105488071/f343bb09.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/106000000/105490000/105488100/105488071/ab517c5d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### ECHO Suites Extended Stay by Wyndham Spartanburg [](https://www.expedia.com/Spartanburg-Hotels-Echo-Suites-Spartanburg-Opening-June-2024.h105488071.Hotel-Information) Spartanburg 8.2/10 Very Good (356 reviews) "It's perfect place to stay." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Changyong $91 nightly $103 total Mar 9 - Mar 10 Total with taxes and fees [](https://www.expedia.com/Spartanburg-Hotels-Echo-Suites-Spartanburg-Opening-June-2024.h105488071.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/990000/988800/988782/67f2e81b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/990000/988800/988782/e439dee7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/990000/988800/988782/355528af.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/1000000/990000/988800/988782/9ab88731.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Spartanburg Marriott [](https://www.expedia.com/Spartanburg-Hotels-Spartanburg-Marriott.h988782.Hotel-Information) Spartanburg 8.6/10 Excellent (1,001 reviews) "great hotel! Clean and awesome restaurant!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Alicia $118 nightly $131 total Mar 15 - Mar 16 Total with taxes and fees [](https://www.expedia.com/Spartanburg-Hotels-Spartanburg-Marriott.h988782.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.com/Hotel-Search?startDate=2026-03-20&endDate=2026-03-21®ionId=553248634999378372&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-us-ca.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## The Annual Vacation Sale Members save up to 40% on hotels and homes. Plan this year’s big trip and save. [Book now](https://expedia.com/deals?rfrr=HTG_SPRING_PROMO_553248634999378372) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.com/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FMayo-Hotels.d553248634999378372.Travel-Guide-Hotels)[ Sign up, it's free ](https://expedia.com/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FMayo-Hotels.d553248634999378372.Travel-Guide-Hotels) ## Top Mayo Hotel Reviews ![Econo Lodge Forest City](https://images.trvl-media.com/lodging/1000000/50000/41900/41874/5f24eb5b_y.jpg) ### Econo Lodge Forest City 10/10 Excellent "Nice place clean rooms " [](https://expedia.com/Forest-City-Hotels-Econo-Lodge.h41874.Hotel-Information) ![ECHO Suites Extended Stay by Wyndham Spartanburg](https://images.trvl-media.com/lodging/106000000/105490000/105488100/105488071/ab517c5d_y.jpg) ### ECHO Suites Extended Stay by Wyndham Spartanburg 10/10 Excellent "The room was great, convenient, and the staff was helpful and friendly. " [](https://expedia.com/Spartanburg-Hotels-Echo-Suites-Spartanburg-Opening-June-2024.h105488071.Hotel-Information) ![Holiday Inn Express I-26 & Us 29 At Westgate Mall by IHG](https://images.trvl-media.com/lodging/1000000/910000/900200/900173/97861c81_y.jpg) ### Holiday Inn Express I-26 & Us 29 At Westgate Mall by IHG 10/10 Excellent "Comfortable beds. Hotel staff was very friendly and accommodating. Daughter forgot her blanket and they even called to let us know so we could come back and get it! " [](https://expedia.com/Spartanburg-Hotels-Holiday-Inn-Express-I-26-Us-29-At-Westgate-Mall.h900173.Hotel-Information) ![HomeTowne Studios by Red Roof Spartanburg - Asheville Highway](https://images.trvl-media.com/lodging/1000000/50000/41700/41656/9b1f8ee9_y.jpg) ### HomeTowne Studios by Red Roof Spartanburg - Asheville Highway 10/10 Excellent "Clean room staff exceptional " [](https://expedia.com/Spartanburg-Hotels-HomeTowne-Studios-By-Red-Roof-Spartanburg-Asheville-Highway.h41656.Hotel-Information) ![Four Points by Sheraton Spartanburg](https://images.trvl-media.com/lodging/1000000/30000/28100/28087/a78c349a_y.jpg) ### Four Points by Sheraton Spartanburg 10/10 Excellent "Clean and nice staff" [](https://expedia.com/Spartanburg-Hotels-Four-Points-By-Sheraton-Spartanburg.h28087.Hotel-Information) ![Best Western Plus Spartanburg](https://images.trvl-media.com/lodging/1000000/300000/297100/297091/cfb611f7_y.jpg) ### Best Western Plus Spartanburg 10/10 Excellent "Yes" [](https://expedia.com/Spartanburg-Hotels-Best-Western-Plus-Spartanburg.h297091.Hotel-Information) ![Tru by Hilton Spartanburg](https://images.trvl-media.com/lodging/49000000/48260000/48251500/48251408/b3b1b4a5_y.jpg) ### Tru by Hilton Spartanburg 10/10 Excellent "A quick in and out pit stop stay for my family on a routine long road trip we’ve had for take a few times. This is the second time we’ve stayed here. And it will be our go to stop. Clean, the breakfast is great. Friendly staff. " [](https://expedia.com/Greenville-Spartanburg-Hotels-Tru-By-Hilton-Spartanburg.h48251408.Hotel-Information) ![Comfort Suites At WestGate Mall](https://images.trvl-media.com/lodging/3000000/2660000/2654400/2654329/1ada0475_y.jpg) ### Comfort Suites At WestGate Mall 4/10 Poor "The room was ok per the pictures. Bed clean, room ok clean. If you don’t like carpet, don’t go there. It reeks of old, mildewed carpet. The ceiling had water damage and looked like it was going to collapse on us at any time. They charged me $123 because they said items were missing. 1 towel, 1 trashcan and a soap dish. I can assure you I didn’t take these items. I also know for a fact that they are lying because I had brought my own towels and had 2 extra. So how did I take " [](https://expedia.com/Spartanburg-Hotels-Comfort-Suites-At-WestGate-Mall.h2654329.Hotel-Information) ![Sleep Inn Spartanburg Southwest](https://images.trvl-media.com/lodging/1000000/50000/42900/42867/5eb71761_y.jpg) ### Sleep Inn Spartanburg Southwest 4/10 Poor "Carpet was sticky and disgusting. Bed sheets and pillow cases dirty. Shower was outdated and disgusting. Water was terrible. Door was uneven so there was huge gaps. We only stayed for a few hours and just left. " [](https://expedia.com/Spartanburg-Hotels-Sleep-Inn.h42867.Hotel-Information) ## More cheap stays in Mayo ![HomeTowne Studios by Red Roof Spartanburg - Asheville Highway](https://images.trvl-media.com/lodging/1000000/50000/41700/41656/9b1f8ee9_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### HomeTowne Studios by Red Roof Spartanburg - Asheville Highway 130 Mobile Drive Spartanburg SC $54 nightly $60 total Apr 1 - Apr 2 Total with taxes and fees 5.4/10 (466 reviews) [](https://expedia.com/Spartanburg-Hotels-HomeTowne-Studios-By-Red-Roof-Spartanburg-Asheville-Highway.h41656.Hotel-Information) ![Sleep Inn Spartanburg Southwest](https://images.trvl-media.com/lodging/1000000/50000/42900/42867/5eb71761_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Sleep Inn Spartanburg Southwest 501 South Blackstock Rd Spartanburg SC $62 nightly $69 total Apr 1 - Apr 2 Total with taxes and fees 6/10 (559 reviews) [](https://expedia.com/Spartanburg-Hotels-Sleep-Inn.h42867.Hotel-Information) ![Econo Lodge Forest City](https://images.trvl-media.com/lodging/1000000/50000/41900/41874/5f24eb5b_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Econo Lodge Forest City 2600 College Ave Forest City NC $64 nightly $72 total Mar 21 - Mar 22 Total with taxes and fees 6.8/10 (341 reviews) [](https://expedia.com/Forest-City-Hotels-Econo-Lodge.h41874.Hotel-Information) ![Holiday Inn Express Gaffney by IHG](https://images.trvl-media.com/lodging/72000000/71520000/71515100/71515054/a9c6228a_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Holiday Inn Express Gaffney by IHG 1031 HYATT STREET Gaffney SC $85 nightly $93 total Mar 15 - Mar 16 Total with taxes and fees 8.8/10 Excellent! (450 reviews) [](https://expedia.com/Gaffney-Hotels-Holiday-Inn-Express-Gaffney.h71515054.Hotel-Information) ![Comfort Suites At WestGate Mall](https://images.trvl-media.com/lodging/3000000/2660000/2654400/2654329/1ada0475_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Comfort Suites At WestGate Mall 458 West Blackstock Road Spartanburg SC $90 nightly $100 total Mar 15 - Mar 16 Total with taxes and fees 8.2/10 Very Good! (1,003 reviews) [](https://expedia.com/Spartanburg-Hotels-Comfort-Suites-At-WestGate-Mall.h2654329.Hotel-Information) ![ECHO Suites Extended Stay by Wyndham Spartanburg](https://images.trvl-media.com/lodging/106000000/105490000/105488100/105488071/ab517c5d_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### ECHO Suites Extended Stay by Wyndham Spartanburg 490 W Blackstock Road Spartanburg SC $91 nightly $103 total Mar 9 - Mar 10 Total with taxes and fees 8.2/10 Very Good! (356 reviews) [](https://expedia.com/Spartanburg-Hotels-Echo-Suites-Spartanburg-Opening-June-2024.h105488071.Hotel-Information) ## Hotels in Mayo with star-rating ![3 Star Hotels](https://images.trvl-media.com/lodging/20000000/19690000/19681400/19681371/84fffc75_z.jpg) 3 Star Hotels 32 properties [](https://expedia.com/3Star-Mayo-Hotels.s30-0-d553248634999378372.Travel-Guide-Filter-Hotels) ![2 Star Hotels](https://images.trvl-media.com/lodging/92000000/91830000/91828000/91827910/6717a2ac_z.jpg) 2 Star Hotels 100 properties [](https://expedia.com/2Star-Mayo-Hotels.s20-0-d553248634999378372.Travel-Guide-Filter-Hotels) ## Frequently asked questions ### What is the best area to stay in Mayo? > This central area of Mayo is where you'll find the majority of local businesses, including eateries and shops. It's a compact and walkable district, making it easy to access amenities. The town hall and the local library are also situated here, providing a central point for navigation. > > > For solo travelers or couples, staying in the town center provides easy access to local dining and any community events that might be happening. ### When is the best time to go to Mayo? > During these periods, the weather is pleasantly mild, with comfortable temperatures and lower humidity, making it ideal for outdoor activities and exploring the local area without the intense heat of summer. You'll find many local events and festivals taking place, offering a great way to experience the community's culture. > > > For travelers looking for a relaxed experience, these seasons offer peaceful surroundings. ### Can I cancel my hotel reservation on Expedia? ### How can I save on a Mayo hotel booking with Expedia? > \*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia, Hotels.com and Vrbo. ### How much is the nightly rate at a Mayo hotel? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rentals - [Hotels near Cowpens National Battlefield ](https://www.expedia.com/Cowpens-National-Battlefield-Hotels.0-l6232435-0.Travel-Guide-Filter-Hotels) - [Chesnee Hotels ](https://www.expedia.com/Chesnee-Hotels.d3000353103.Travel-Guide-Hotels) - [Cabin Rentals in Chesnee ](https://www.expedia.com/Chesnee-Cabins.d3000353103-aaCabins.Travel-Guide-Accommodation) - [Red Roof Inn Hotels in Chesnee ](https://www.expedia.com/Chesnee-Hotels-Red-Roof-Inn.0-0-d3000353103--bRedRoofInn.Travel-Guide-Filter-Hotels) - [B&B in Chesnee ](https://www.expedia.com/Chesnee-Bed-And-Breakfast.d3000353103-aaBedAndBreakfast.Travel-Guide-Accommodation) - [Rv Parks in Chesnee ](https://www.expedia.com/Chesnee-RV-Parks.d3000353103-aaRVParks.Travel-Guide-Accommodation) - [5 Star Hotels in Chesnee ](https://www.expedia.com/5Star-Chesnee-Hotels.s50-0-d3000353103.Travel-Guide-Filter-Hotels) - 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