Find hotels in Mayo, SC from $65

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Next weekend
May 22 - May 24
In two weeks
May 29 - May 31

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Our top choices for Mayo hotels

Exterior

University Inn

University Inn
2.5 star property
Shelby
8.6 out of 10, Excellent, (471 reviews)
"The room was very quiet and clean the staff were very nice and friendly "
United States
Theresa
$104 nightly
The price is $117
Jun 7 - Jun 8
Total with taxes and fees
University Inn
Standard Room, 2 Queen Beds, Smoking, Kitchen | Bed sheets

Studio 6 – Spindale, NC – Forest City

Studio 6 – Spindale, NC – Forest City
2.0 star property
Spindale
$61 nightly
The price is $69
May 23 - May 24
Total with taxes and fees
Studio 6 – Spindale, NC – Forest City
Free daily buffet breakfast

Hampton Inn Gaffney

Hampton Inn Gaffney
2.5 star property
Gaffney
8.8 out of 10, Excellent, (717 reviews)
"Would stay again breakfast was amazing "
United States
Theresa
$83 nightly
The price is $91
May 31 - Jun 1
Total with taxes and fees
Hampton Inn Gaffney
Lobby

Quality Inn Gaffney I-85

Quality Inn Gaffney I-85
2.5 star property
Gaffney
7.6 out of 10, Good, (401 reviews)
"Jay, is a wonderful customer rep and the rest of the staff has always been very helpful and accommodating."
United States
Raines
$59 nightly
The price is $66
May 28 - May 29
Total with taxes and fees
Quality Inn Gaffney I-85
Desk, laptop workspace, blackout drapes, free WiFi

Motel 6 Spartanburg, Sc – Northwest / Business 85

Motel 6 Spartanburg, Sc – Northwest / Business 85
2.0 star property
Spartanburg
7.6 out of 10, Good, (120 reviews)
"I loved everything about my stay"
United States
Anthony
$61 nightly
The price is $68
May 18 - May 19
Total with taxes and fees
Motel 6 Spartanburg, Sc – Northwest / Business 85
Lobby

Baymont by Wyndham Gaffney

Baymont by Wyndham Gaffney
2.5 star property
Gaffney
7.4 out of 10, Good, (692 reviews)
"Rooms are okay not spacious enough andd water could get a lttle hotter . Staff was nice. Its parking was able to park right infront of my room door. "
United States
Karin
$72 nightly
The price is $81
Jun 7 - Jun 8
Total with taxes and fees
Baymont by Wyndham Gaffney
Free daily full breakfast

Holiday Inn Express Gaffney by IHG

Holiday Inn Express Gaffney by IHG
2.5 star property
Gaffney
8.8 out of 10, Excellent, (488 reviews)
"Room very clean staff was great breakfast was really good with lots of options "
United States
melvin
$85 nightly
The price is $93
May 31 - Jun 1
Total with taxes and fees
Holiday Inn Express Gaffney by IHG
Exterior

Tryon Resort

Tryon Resort
3.0 star property
Rutherfordton
9.4 out of 10, Exceptional, (25 reviews)
"Wonderful accommodations"
United States
Lisa
$179 nightly
The price is $196
May 18 - May 19
Total with taxes and fees
Tryon Resort
Exterior

Quality Inn Forest City

Quality Inn Forest City
2.5 star property
Forest City
7.6 out of 10, Good, (328 reviews)
"Staff was friendly and the room was clean. "
United States
Danielle
$75 nightly
The price is $85
May 23 - May 24
Total with taxes and fees
Quality Inn Forest City
Reception

Red Roof Inn Gaffney

Red Roof Inn Gaffney
2.0 star property
Gaffney
7.2 out of 10, Good, (444 reviews)
"Clean room friendly staff"
United States
Melissa
$66 nightly
The price is $74
May 24 - May 25
Total with taxes and fees
Red Roof Inn Gaffney
Desk, blackout drapes, iron/ironing board, free cribs/infant beds

Days Inn by Wyndham Spartanburg Waccamaw

Days Inn by Wyndham Spartanburg Waccamaw
2.0 star property
Spartanburg
7.4 out of 10, Good, (859 reviews)
"Good stay , room was clean and comfortable "
United States
Samir
$59 nightly
The price is $65
Jun 5 - Jun 6
Total with taxes and fees
Days Inn by Wyndham Spartanburg Waccamaw
Lobby sitting area

Econo Lodge Forest City

Econo Lodge Forest City
2.0 star property
Forest City
7.2 out of 10, Good, (395 reviews)
"Nothing fancy but the rooms were clean"
United States
Alisha
$60 nightly
The price is $67
May 31 - Jun 1
Total with taxes and fees
Econo Lodge Forest City
Reception

Hampton Inn Spartanburg-North I-85

Hampton Inn Spartanburg-North I-85
2.5 star property
Spartanburg
8.6 out of 10, Excellent, (1,001 reviews)
"Clean. Quiet. "
United States
Nancy
$84 nightly
The price is $93
May 27 - May 28
Total with taxes and fees
Hampton Inn Spartanburg-North I-85
Free daily continental breakfast

Quality Inn Duncan - Spartanburg West

Quality Inn Duncan - Spartanburg West
2.5 star property
Duncan
7.8 out of 10, Good, (386 reviews)
"good"
United States
Volodymyr
$65 nightly
The price is $72
Jun 16 - Jun 17
Total with taxes and fees
Quality Inn Duncan - Spartanburg West
Interior entrance

SUN AND SAND MOTEL

SUN AND SAND MOTEL
2.0 star property
Spartanburg
7.6 out of 10, Good, (26 reviews)
"Great location "
United States
Tracy
$62 nightly
The price is $69
May 22 - May 23
Total with taxes and fees
SUN AND SAND MOTEL
Exterior

Baymont by Wyndham Forest City

Baymont by Wyndham Forest City
2.5 star property
Forest City
7.4 out of 10, Good, (734 reviews)
"Wouldn’t stay there again"
United States
Wayne
$63 nightly
The price is $71
May 24 - May 25
Total with taxes and fees
Baymont by Wyndham Forest City
Free on-the-go breakfast on weekends

Sleep Inn Gaffney at I-85

Sleep Inn Gaffney at I-85
2.5 star property
Gaffney
7.6 out of 10, Good, (341 reviews)
"Ladies at check in and out were awesome."
United States
Robert
$76 nightly
The price is $85
Jun 7 - Jun 8
Total with taxes and fees
Sleep Inn Gaffney at I-85
Terrace/patio

Hampton Inn & Suites Forest City

Hampton Inn & Suites Forest City
2.5 star property
Forest City
9.4 out of 10, Exceptional, (429 reviews)
"clean room, breakfast, great staff!!"
United States
Edna
$147 nightly
The price is $166
May 24 - May 25
Total with taxes and fees
Hampton Inn & Suites Forest City
Lobby

USA Economy Lodge

USA Economy Lodge
2.0 star property
Spartanburg
7.8 out of 10, Good, (102 reviews)
"Clean lodging and professional and friendly staff."
United States
Jonathan
$71 nightly
The price is $78
May 18 - May 19
Total with taxes and fees
USA Economy Lodge
Exterior

Holiday Inn Express Hotel & Suites Spartanburg-North by IHG

Holiday Inn Express Hotel & Suites Spartanburg-North by IHG
2.5 star property
Spartanburg
8.6 out of 10, Excellent, (923 reviews)
"The breakfast was very good and the room was clean and well maintained. "
United States
JAY
$91 nightly
The price is $101
May 31 - Jun 1
Total with taxes and fees
Holiday Inn Express Hotel & Suites Spartanburg-North by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Mayo Hotel Reviews

Holiday Inn Express I-26 & Us 29 At Westgate Mall by IHG

Holiday Inn Express I-26 & Us 29 At Westgate Mall by IHG

10/10 Excellent
"Great breakfast and room was extremely clean bed was extremely comfortable. I will definitely be staying again when I return to SC."
Tara 1-night trip
Posted 2 hours ago
Holiday Inn Express I-26 & Us 29 At Westgate Mall by IHG

More cheap stays in Mayo

Days Inn by Wyndham Spartanburg Waccamaw

Days Inn by Wyndham Spartanburg Waccamaw

101 Outlet Rd Spartanburg SC
$59 nightly
The price is $65 total per night from Jun 5 to Jun 6
$65 total
Jun 5 - Jun 6
Total with taxes and fees
7.4/10 Good! (859 reviews)

Hotels in Mayo with star-rating

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Frequently asked questions

What is the best area to stay in Mayo?
The best area to stay in Mayo is the town center, particularly around Main Street, as it offers the most convenience for visitors.

This central area of Mayo is where you'll find the majority of local businesses, including eateries and shops. It's a compact and walkable district, making it easy to access amenities. The town hall and the local library are also situated here, providing a central point for navigation.

For solo travelers or couples, staying in the town center provides easy access to local dining and any community events that might be happening.
When is the best time to go to Mayo?
The best time to visit Mayo, South Carolina, is during the spring (April to June) and fall (September to November) months.

During these periods, the weather is pleasantly mild, with comfortable temperatures and lower humidity, making it ideal for outdoor activities and exploring the local area without the intense heat of summer. You'll find many local events and festivals taking place, offering a great way to experience the community's culture.

For travelers looking for a relaxed experience, these seasons offer peaceful surroundings.
Can I cancel my hotel reservation on Expedia?
You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Mayo.
How can I save on a Mayo hotel booking with Expedia?
With Expedia, you earn OneKeyCash™* on eligible Mayo hotel bookings for every dollar you spend – just join our One Key™ travel rewards program to get started. It's free to join, and you'll unlock our lowest Member Prices as soon as you're signed in. On top of this, you could also save significantly by bundling your hotel and flights together on Expedia.

*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia, Hotels.com and Vrbo.
How much is the nightly rate at a Mayo hotel?
Prices for hotels in Mayo often vary, but you can find a great deal from $65 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate.

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