Title: Visit Mayo: 2026 Travel Guide for Mayo, Cowpens | Expedia.com [Hotels in Mayo](https://expedia.com/Mayo-Hotels.d553248634999378372.Travel-Guide-Hotels)[Vacation Rentals in Mayo](https://expedia.com/Mayo-Vacation-Rentals.d553248634999378372.Travel-Guide-VacationRentals)[Car Rentals in Mayo](https://expedia.com/Car-Rentals-In-Mayo.d553248634999378372.Car-Rental-Guide)[Mayo Vacation Packages](https://expedia.com/Mayo.d553248634999378372.Destination-Travel-Guides) # Mayo, SC ## Travel Guide ## Visit Mayo Things to do - Mayo Hotel Deals - Vacation Rentals in Mayo ![Comfort Suites At WestGate Mall](https://images.trvl-media.com/lodging/3000000/2660000/2654400/2654329/1ada0475_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Comfort Suites At WestGate Mall 458 West Blackstock Road Spartanburg SC $90 nightly $100 total Mar 1 - Mar 2 Total with taxes and fees Book a stay at this business-friendly hotel in Spartanburg. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ... 8.2/10 Very Good! (1,000 reviews) The MOTEL NOT HOTEL IS OLD AND NEGLECTED. There is no elevator but only a lift. The place is dirty and falling apart. Reviewed on Feb 25, 2026 [](https://expedia.com/Hotel-Search?startDate=3%2F1%2F2026&endDate=3%2F2%2F2026&selected=2654329&PinnedHotelID=2654329&HadPinnedHotel=true®ionId=553248634999378372) ![Sleep Inn Spartanburg Southwest](https://images.trvl-media.com/lodging/1000000/50000/42900/42867/5eb71761_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Sleep Inn Spartanburg Southwest 501 South Blackstock Rd Spartanburg SC $64 nightly $71 total Mar 29 - Mar 30 Total with taxes and fees Book a stay at this business-friendly hotel in Spartanburg. Enjoy free breakfast, free WiFi, and free parking. Popular attractions WestGate Mall and Regal Spartan ... 5.8/10 (551 reviews) The manager is awful, bad, terrible. Racist. Rude. Disrespect person. I was charged the full security deposit for no reason at all. Ive currently got pending investigation with my bank to have returned as I was not rightfully charged not to mention it was not only charged my credit card but also ... Reviewed on Feb 26, 2026 [](https://expedia.com/Hotel-Search?startDate=3%2F29%2F2026&endDate=3%2F30%2F2026&selected=42867&PinnedHotelID=42867&HadPinnedHotel=true®ionId=553248634999378372) ![ECHO Suites Extended Stay by Wyndham Spartanburg](https://images.trvl-media.com/lodging/106000000/105490000/105488100/105488071/ab517c5d_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### ECHO Suites Extended Stay by Wyndham Spartanburg 490 W Blackstock Road Spartanburg SC $93 nightly $105 total Mar 1 - Mar 2 Total with taxes and fees Book a stay at this business-friendly hotel in Spartanburg. Enjoy free WiFi, free parking, and a 24-hour fitness center. Popular attractions Regal Spartan and ... 8.2/10 Very Good! (351 reviews) No hair driers in rooms had to go front office The hotel was pet friendly but still had to pay $ per day Reviewed on Feb 23, 2026 [](https://expedia.com/Hotel-Search?startDate=3%2F1%2F2026&endDate=3%2F2%2F2026&selected=105488071&PinnedHotelID=105488071&HadPinnedHotel=true®ionId=553248634999378372) [See all 456 properties in Mayo](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.DestinationExperience&startDate=2%2F28%2F2026&endDate=3%2F1%2F2026®ionId=553248634999378372) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ![Cozy cabin in charming Columbus. Minutes from Equestrian Center, vineyards etc..](https://images.trvl-media.com/lodging/111000000/110140000/110137300/110137220/a36ba28c_edited_83c8_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Cozy cabin in charming Columbus. Minutes from Equestrian Center, vineyards etc.. Columbus NC Stay at this cabin in Columbus. Enjoy a garden, laundry facilities, and patios. Popular attractions Green Creek Winery and Overmountain Vineyards are located ... 9.8/10 Exceptional! (19 reviews) The house was very clean, tastefully decorated and provided all that we needed for a short trip. The setting is beautiful, wooded and great for nature lovers. The host was very helpful. Reviewed on Feb 22, 2026 [](https://expedia.com/Columbus-Hotels-Cozy-Cabin-In-Charming-Columbus-Minutes-From-Equestrian-Center.h110137220.Hotel-Information) ![Home Sweet Home](https://images.trvl-media.com/lodging/110000000/109320000/109317600/109317542/68f3df65_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Home Sweet Home Spartanburg SC Stay at this vacation home in Spartanburg. Enjoy laundry facilities and air conditioning. Popular attractions River Falls Golf Course and Tyger River Park are ... 9.8/10 Exceptional! (22 reviews) Very Comfortable & Nice. The only issue we had was there was no patio furniture or grill. Reviewed on Dec 27, 2025 [](https://expedia.com/Spartanburg-Hotels-Home-Sweet-Home.h109317542.Hotel-Information) ![ Grain Bin Silo Tiny House with 1 bedroom, WiFi, AC and hot tub in Shelby](https://images.trvl-media.com/lodging/109000000/108260000/108256800/108256785/9e1a5cf1_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Grain Bin Silo Tiny House with 1 bedroom, WiFi, AC and hot tub in Shelby Shelby NC Stay at this apartment in Shelby. Enjoy air conditioning and a hot tub. Popular attractions Shelby City Park and Shelby City Carousel are located nearby. 10/10 Exceptional! (26 reviews) We had the best time staying at The Silo. My wife and I enjoy the peaceful sound of the stream beside the porch and the hospitality provided. It was very clean, safe and the perfect spot for the two of us. Reviewed on Feb 23, 2026 [](https://expedia.com/Shelby-Hotels-Luxury-Grain-Bin-Silo-With-1-Bedroom.h108256785.Hotel-Information) [See all properties in Mayo](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.DestinationExperience®ionId=553248634999378372&sort=VACATION_RENTAL) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Check Mayo hotel availability [Tonight ](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248634999378372&startDate=2026-02-27&endDate=2026-02-28)[Feb 27 - Feb 28](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248634999378372&startDate=2026-02-27&endDate=2026-02-28) [Tomorrow night ](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248634999378372&startDate=2026-02-28&endDate=2026-03-01)[Feb 28 - Mar 1](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248634999378372&startDate=2026-02-28&endDate=2026-03-01) [This weekend ](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248634999378372&startDate=2%2F27%2F2026&endDate=3%2F1%2F2026)[Feb 27 - Mar 1](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248634999378372&startDate=2%2F27%2F2026&endDate=3%2F1%2F2026) ### Popular places to visit #### Cowpens Library Cowpens Library is just one of the places to see in Cowpens, so why not enjoy the other things to explore during your travels? [](https://expedia.com/Cowpens-Library-Cowpens.d911209921771835392.Vacation-Attraction) #### Cowpens Veterans Memorial Park Cowpens Veterans Memorial Park is just one of the places to see in Cowpens, so why not enjoy the other things to explore during your travels? [](https://expedia.com/Cowpens-Veterans-Memorial-Park-Cowpens.d911209212248682496.Vacation-Attraction) #### Cowpens Depot Museum and Civic Center You can spend time studying the exhibits at Cowpens Depot Museum and Civic Center during your travels in Cowpens. [](https://expedia.com/Cowpens-Depot-Museum-And-Civic-Center-Cowpens.d911208872029802496.Vacation-Attraction) ## Cities near Mayo ![Cowpens National Battlefield Park, in South Carolina, Major Battlefield of the American Revolutionary War](https://images.trvl-media.com/place/3000353103/b8895d04-2a10-4596-9fbd-eddc576cc6e0.jpg?impolicy=fcrop&w=512&h=288&q=medium) ### Chesnee - Cities near Mayo - Places of interest [Chesnee](https://expedia.com/Chesnee.dx3000353103) - [Tryon International Equestrian Center ](https://expedia.com/Tryon-International-Equestrian-Center-North-Carolina.d553248621576385451.Vacation-Attraction) - [Spartanburg Memorial Auditorium ](https://expedia.com/Spartanburg-Memorial-Auditorium-Spartanburg.d6245714.Vacation-Attraction) - [WestGate Mall ](https://expedia.com/WestGate-Mall-Spartanburg.d6144854.Vacation-Attraction) - [Wofford College ](https://expedia.com/Wofford-College-Spartanburg.d6245696.Vacation-Attraction) - [Tyger River Park ](https://expedia.com/Tyger-River-Park-Spartanburg.d553248621563220556.Vacation-Attraction) - [University of South Carolina Upstate ](https://expedia.com/University-Of-South-Carolina-Upstate-Spartanburg.d6245722.Vacation-Attraction) - [Gardner-Webb University ](https://expedia.com/Gardner-Webb-University-North-Carolina.d553248635975474846.Vacation-Attraction) - [Spartanburg Regional Hospital ](https://expedia.com/Spartanburg-Regional-Hospital-Spartanburg.d6245689.Vacation-Attraction) - [Converse College ](https://expedia.com/Converse-College-Spartanburg.d6144852.Vacation-Attraction) - [Lake Bowen ](https://expedia.com/Lake-Bowen-South-Carolina.d694541776719945728.Vacation-Attraction) - [Foothills Equestrian Nature ](https://expedia.com/Foothills-Equestrian-Nature-Tryon.d553248634467744586.Vacation-Attraction) - [Green River ](https://expedia.com/Green-River-North-Carolina.d681791294174527488.Vacation-Attraction) - [Gaffney Outlet Marketplace ](https://expedia.com/Gaffney-Outlet-Marketplace-Gaffney.d6232433.Vacation-Attraction) - [295 Sports Complex ](https://expedia.com/295-Sports-Complex-Spartanburg.d6245676.Vacation-Attraction) - [Mountain Brook Vineyards ](https://expedia.com/Mountain-Brook-Vineyards-Tryon.d553248621561872027.Vacation-Attraction) - [Spartanburg Methodist College ](https://expedia.com/Spartanburg-Methodist-College-Spartanburg.d6144849.Vacation-Attraction) - [Cowpens National Battlefield ](https://expedia.com/Cowpens-National-Battlefield-South-Carolina.d6232435.Vacation-Attraction) - [Morgan Square ](https://expedia.com/Morgan-Square-Spartanburg.d553248621587242575.Vacation-Attraction) - [Hollywild Animal Park ](https://expedia.com/Hollywild-Animal-Park-Wellford.d6245704.Vacation-Attraction) - [Jerry Richardson Indoor Stadium ](https://expedia.com/Jerry-Richardson-Indoor-Stadium-Spartanburg.d693200666273492992.Vacation-Attraction) - [Spartanburg Expo Center ](https://expedia.com/Spartanburg-Expo-Center-Spartanburg.d6245708.Vacation-Attraction) - [Overmountain Vineyards ](https://expedia.com/Overmountain-Vineyards-Tryon.d6326236.Vacation-Attraction) - [Shipwreck Cove ](https://expedia.com/Shipwreck-Cove-Duncan.d553248621532656800.Vacation-Attraction) - [River Falls Golf Course ](https://expedia.com/River-Falls-Golf-Course-Duncan.d6245662.Vacation-Attraction) - [Forest City Golf Course ](https://expedia.com/Forest-City-Golf-Course-Forest-City.d6209537.Vacation-Attraction) - [Russian Chapel Hills Winery ](https://expedia.com/Russian-Chapel-Hills-Winery-Columbus.d553248621561872026.Vacation-Attraction) - [Walnut Grove Plantation ](https://expedia.com/Walnut-Grove-Plantation-Roebuck.d553248621532656801.Vacation-Attraction) - [Cleghorn Plantation Golf and Country Club ](https://expedia.com/Cleghorn-Plantation-Golf-And-Country-Club-Rutherfordton.d553248621532657093.Vacation-Attraction) - [Croft State Park ](https://expedia.com/Croft-State-Park-Spartanburg.d553248621532656807.Vacation-Attraction) ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save even more - get up to 20% on select hotels when you book on the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. 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