Title: Lignumvitae Key Botanical State Park Vacation Rentals from $311: Search Short-Term Rentals | Expedia.com

[Lignumvitae Key Botanical State Park Travel Guide](https://expedia.com/Lignumvitae-Key-Botanical-State-Park.dx553248621532652349)[Hotels in Lignumvitae Key Botanical State Park](https://expedia.com/Lignumvitae-Key-Botanical-State-Park-Hotels.d553248621532652349.Travel-Guide-Hotels)[Flights to Lignumvitae Key Botanical State Park](https://expedia.com/Cheap-Flights-To-Lignumvitae-Key-Botanical-State-Park.d553248621532652349.Travel-Guide-Flights)[Car Rentals in Lignumvitae Key Botanical State Park](https://expedia.com/Car-Rentals-In-Lignumvitae-Key-Botanical-State-Park.d553248621532652349.Car-Rental-Guide)[Lignumvitae Key Botanical State Park Vacation Packages](https://expedia.com/Lignumvitae-Key-Botanical-State-Park.d553248621532652349.Destination-Travel-Guides)

![3/4 of a mile paddle from islamorada. There are still ruins and one grave with historic markers from the early settlements of Indians, spanish and american ship wreckers. The island is accessible by paddling or boat.](https://images.trvl-media.com/place/10768/cc086a75-d19c-4609-99ea-434de5d33788.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

Photo by RVOutlawz

![](https://images.trvl-media.com/place/10768/cc086a75-d19c-4609-99ea-434de5d33788.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

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## Check prices for these dates

In two weeks

[Feb 27 - Mar 1](https://www.expedia.com/Hotel-Search?regionId=553248621532652349&startDate=2026-02-27&endDate=2026-03-01&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In two months

[Apr 10 - Apr 12](https://www.expedia.com/Hotel-Search?regionId=553248621532652349&startDate=2026-04-10&endDate=2026-04-12&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In three months

[May 8 - May 10](https://www.expedia.com/Hotel-Search?regionId=553248621532652349&startDate=2026-05-08&endDate=2026-05-10&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In four months

[Jun 5 - Jun 7](https://www.expedia.com/Hotel-Search?regionId=553248621532652349&startDate=2026-06-05&endDate=2026-06-07&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

## Our top choices for Lignumvitae Key Botanical State Park vacation rentals

![25-inch flat-screen TV with digital channels, TV](https://images.trvl-media.com/lodging/92000000/91750000/91743100/91743042/12c235b3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Premium bedding, individually decorated, free WiFi, bed sheets](https://images.trvl-media.com/lodging/92000000/91750000/91743100/91743042/b0169681.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/92000000/91750000/91743100/91743042/17a61bb5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![25-inch flat-screen TV with digital channels, TV](https://images.trvl-media.com/lodging/92000000/91750000/91743100/91743042/92a650b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Treasure Harbor

[](https://www.expedia.com/Islamorada-Hotels-Treasure-Harbor.h91743042.Hotel-Information)

Islamorada

9.0/10

Wonderful

(129 reviews)

"Very peaceful and comfortable stay! Dallas and Hannah were amazing hosts! Thank you so much !"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Nick

$276 nightly

$311 total

Feb 12 - Feb 13

Total with taxes and fees

[](https://www.expedia.com/Islamorada-Hotels-Treasure-Harbor.h91743042.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/12000000/11950000/11945900/11945889/19240ce2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Standard Room, 1 Bedroom, Kitchen, Pool View | Living area | TV](https://images.trvl-media.com/lodging/12000000/11950000/11945900/11945889/3602f78f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![On the beach, beach towels](https://images.trvl-media.com/lodging/12000000/11950000/11945900/11945889/4550dbd5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Economy Room | 1 bedroom, free WiFi](https://images.trvl-media.com/lodging/12000000/11950000/11945900/11945889/f0ed1fc9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Breezy Palms Resort

[](https://www.expedia.com/Islamorada-Hotels-Breezy-Palms-Resort.h11945889.Hotel-Information)

Matecumbe

8.8/10

Excellent

(617 reviews)

"Friendly staff, beautiful peaceful beach, great room with a big comfy bed and all that you might need. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Alexander

$276 nightly

$311 total

Feb 12 - Feb 13

Total with taxes and fees

[](https://www.expedia.com/Islamorada-Hotels-Breezy-Palms-Resort.h11945889.Hotel-Information)

![Pool](https://images.trvl-media.com/lodging/64000000/63120000/63112600/63112538/82e6e9b1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Beach nearby, sun loungers, beach towels](https://images.trvl-media.com/lodging/64000000/63120000/63112600/63112538/9d4d58bb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/64000000/63120000/63112600/63112538/c35a47ac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/64000000/63120000/63112600/63112538/0464ff2e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Amazing Ocean view condo

[](https://www.expedia.com/Tavernier-Hotels-Amazing-Ocean-View-Condo.h63112538.Hotel-Information)

Tavernier

9.6/10

Exceptional

(43 reviews)

"Exceeded expectations, exceptionally clean, great for kids (they loved the pool), perfect for our Keys trip"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Natalie M.

$381 nightly

$423 total

Mar 1 - Mar 2

Total with taxes and fees

[](https://www.expedia.com/Tavernier-Hotels-Amazing-Ocean-View-Condo.h63112538.Hotel-Information)

![On the beach](https://images.trvl-media.com/lodging/54000000/53650000/53645500/53645406/0ad9df61.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/54000000/53650000/53645500/53645406/3a4de8ac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/54000000/53650000/53645500/53645406/c854d590.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Marina](https://images.trvl-media.com/lodging/54000000/53650000/53645500/53645406/8d386ddb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Serenity In The Sun Condo Fabulous Ocean View

[](https://www.expedia.com/Tavernier-Hotels-Serenity-In-The-Sun-Condo-Fabulous-Ocean-View.h53645406.Hotel-Information)

Tavernier

10/10

Exceptional

(108 reviews)

"Fantastic place to stay! Very clean and great hosts. Will stay again. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Les

$500 nightly

$555 total

Mar 10 - Mar 11

Total with taxes and fees

[](https://www.expedia.com/Tavernier-Hotels-Serenity-In-The-Sun-Condo-Fabulous-Ocean-View.h53645406.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/91000000/90530000/90524700/90524666/83b3602f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![A heated pool](https://images.trvl-media.com/lodging/91000000/90530000/90524700/90524666/2f4fe73c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/91000000/90530000/90524700/90524666/b33bbeb4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/91000000/90530000/90524700/90524666/94e72557.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Florida Keys Getaway - Slps 4 - Ocean View

[](https://www.expedia.com/Tavernier-Hotels-Florida-Keys-Getaway-Slps-4-Ocean-View.h90524666.Hotel-Information)

Tavernier

9.6/10

Exceptional

(20 reviews)

"Everything was just as described in the condo listing. We enjoyed the pool and hot tub. Wonderful location to explore the Keys. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Michele G.

$336 nightly

$373 total

Feb 12 - Feb 13

Total with taxes and fees

[](https://www.expedia.com/Tavernier-Hotels-Florida-Keys-Getaway-Slps-4-Ocean-View.h90524666.Hotel-Information)

![Beach nearby](https://images.trvl-media.com/lodging/78000000/77940000/77937700/77937661/076d9453.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/78000000/77940000/77937700/77937661/2a8b327f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/78000000/77940000/77937700/77937661/93009341.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/78000000/77940000/77937700/77937661/587442a1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Paradise in Key Largo Florida 2

[](https://www.expedia.com/Key-Largo-Hotels-Paradise-In-Key-Largo-Florida.h77937661.Hotel-Information)

Key Largo

9.8/10

Exceptional

(41 reviews)

"The cleanliness, the availability, the comfort. Everything was perfect in fact. Vz are planning on contacting the owner and tomorrow maybe arrange another rental on that property. It was in the perfect spot walking distance to the pool. Everything was readily available. Everything that they advertised was actually above and beyond. Our expectations can't say enough. Good about it was a perfect vacation. Thank you"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Steve V.

$367 nightly

$408 total

Mar 11 - Mar 12

Total with taxes and fees

[](https://www.expedia.com/Key-Largo-Hotels-Paradise-In-Key-Largo-Florida.h77937661.Hotel-Information)

![Marina](https://images.trvl-media.com/lodging/97000000/96480000/96473300/96473229/w905h683x60y0-10596317.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 bedrooms, in-room safe, desk, bed sheets](https://images.trvl-media.com/lodging/97000000/96480000/96473300/96473229/w905h683x60y0-853e5b0d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/97000000/96480000/96473300/96473229/w903h683x60y0-ed597f77.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Books](https://images.trvl-media.com/lodging/97000000/96480000/96473300/96473229/w905h683x60y0-4fee4dcd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Island Sanctuary Islamorada

[](https://www.expedia.com/Tavernier-Hotels-Island-Sanctuary-Islamorada.h96473229.Hotel-Information)

Tavernier

9.8/10

Exceptional

(15 reviews)

"An amazing place to switch gears. Great host. Win/win."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Alex Z.

$375 nightly

$416 total

Feb 11 - Feb 12

Total with taxes and fees

[](https://www.expedia.com/Tavernier-Hotels-Island-Sanctuary-Islamorada.h96473229.Hotel-Information)

![Beach](https://images.trvl-media.com/lodging/100000000/99380000/99379100/99379050/fec364af.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/100000000/99380000/99379100/99379050/58ae0676.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Marina](https://images.trvl-media.com/lodging/100000000/99380000/99379100/99379050/0571d5ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/100000000/99380000/99379100/99379050/f784540b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### RV by the Sea - Glamping in the Keys - Sleeps 6

[](https://www.expedia.com/Key-Largo-Hotels-RV-By-The-Sea-Glamping-In-The-Keys-Sleeps-6.h99379050.Hotel-Information)

Key Largo

9.0/10

Wonderful

(21 reviews)

"The camper was clean and comfortable. The extras for the beach were great."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

SUSAN C.

$282 nightly

$315 total

Mar 5 - Mar 6

Total with taxes and fees

[](https://www.expedia.com/Key-Largo-Hotels-RV-By-The-Sea-Glamping-In-The-Keys-Sleeps-6.h99379050.Hotel-Information)

![Property grounds](https://images.trvl-media.com/lodging/102000000/101240000/101232100/101232074/0864a30f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Pool](https://images.trvl-media.com/lodging/102000000/101240000/101232100/101232074/dea19358.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/102000000/101240000/101232100/101232074/93ccee81.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/102000000/101240000/101232100/101232074/898c467c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Cozy place in Calusa Key Largo

[](https://www.expedia.com/Key-Largo-Hotels-Cozy-Place-In-Calusa-Key-Largo.h101232074.Hotel-Information)

Key Largo

9.0/10

Wonderful

(14 reviews)

"Perfect weekend getaway location."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Tex H.

$341 nightly

$379 total

Feb 25 - Feb 26

Total with taxes and fees

[](https://www.expedia.com/Key-Largo-Hotels-Cozy-Place-In-Calusa-Key-Largo.h101232074.Hotel-Information)

![2 bedrooms, desk, free WiFi, bed sheets](https://images.trvl-media.com/lodging/79000000/78540000/78534000/78533920/1f7903f7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/79000000/78540000/78534000/78533920/05728622.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![](https://images.trvl-media.com/lodging/79000000/78540000/78534000/78533920/30e492b4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Dining](https://images.trvl-media.com/lodging/79000000/78540000/78534000/78533920/0dd2c572.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Where the sea, sun, and sand are just outside your door!

[](https://www.expedia.com/Key-Largo-Hotels-Welcome-To-Paradise-II.h78533920.Hotel-Information)

Key Largo

9.6/10

Exceptional

(31 reviews)

"Everything is as described. We brought our boat and used the marina. Our trailer fit on the property’s as well. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Jane O.

$349 nightly

$388 total

Feb 11 - Feb 12

Total with taxes and fees

[](https://www.expedia.com/Key-Largo-Hotels-Welcome-To-Paradise-II.h78533920.Hotel-Information)

![Beach nearby](https://images.trvl-media.com/lodging/79000000/78260000/78256400/78256350/9bc23a15.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/79000000/78260000/78256400/78256350/079f8926.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/79000000/78260000/78256400/78256350/5a93ef3c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Pool](https://images.trvl-media.com/lodging/79000000/78260000/78256400/78256350/b17c222a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### 3212 Across from Pool \* King & Queen/Twin Bunk Bed

[](https://www.expedia.com/Tavernier-Hotels-Modern-Coastal-Renovation.h78256350.Hotel-Information)

Tavernier

9.8/10

Exceptional

(152 reviews)

"Great stay lovely home "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Yezenia

$475 nightly

$518 total

Mar 4 - Mar 5

Total with taxes and fees

[](https://www.expedia.com/Tavernier-Hotels-Modern-Coastal-Renovation.h78256350.Hotel-Information)

![Beach nearby](https://images.trvl-media.com/lodging/88000000/87830000/87824100/87824083/f37f6bd9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/88000000/87830000/87824100/87824083/661fb6e3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![TV](https://images.trvl-media.com/lodging/88000000/87830000/87824100/87824083/ff77d497.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/88000000/87830000/87824100/87824083/d09ea2c6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Blue Haven Key Largo | Ocean Pointe 1315

[](https://www.expedia.com/Tavernier-Hotels-Blue-Haven-Key-Largo-Ocean-Pointe-1315.h87824083.Hotel-Information)

Tavernier

9.6/10

Exceptional

(15 reviews)

"Loved this condo. Had all the amenities we needed and was super clean and tidy. Will definitely be staying here again. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Rodney B.

$481 nightly

$524 total

Mar 4 - Mar 5

Total with taxes and fees

[](https://www.expedia.com/Tavernier-Hotels-Blue-Haven-Key-Largo-Ocean-Pointe-1315.h87824083.Hotel-Information)

![Smart TV](https://images.trvl-media.com/lodging/100000000/99970000/99961500/99961430/006a1068.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 bedrooms, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/100000000/99970000/99961500/99961430/b3fdbd21.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor dining](https://images.trvl-media.com/lodging/100000000/99970000/99961500/99961430/301698a1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/100000000/99970000/99961500/99961430/078f0b06.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Charming Home in Key Largo

[](https://www.expedia.com/Key-Largo-Hotels-Charming-Home-In-Key-Largo.h99961430.Hotel-Information)

Key Largo

9.8/10

Exceptional

(30 reviews)

"Great location. Very clean very nice, stay there again"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Mark B.

$447 nightly

$497 total

Feb 12 - Feb 13

Total with taxes and fees

[](https://www.expedia.com/Key-Largo-Hotels-Charming-Home-In-Key-Largo.h99961430.Hotel-Information)

![Beach nearby](https://images.trvl-media.com/lodging/108000000/107450000/107445700/107445689/55a120e1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Marina](https://images.trvl-media.com/lodging/108000000/107450000/107445700/107445689/2bdc7822.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/108000000/107450000/107445700/107445689/ae7ae6fd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/108000000/107450000/107445700/107445689/087c8d3e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Paradise Palms 2 Bedroom Condo Ocean Pointe 1206

[](https://www.expedia.com/Tavernier-Hotels-Paradise-Palms-Ocean-Pointe-1206.h107445689.Hotel-Information)

Tavernier

9.8/10

Exceptional

(6 reviews)

"Thanks for your great hospitality."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

richard

$469 nightly

$511 total

Mar 4 - Mar 5

Total with taxes and fees

[](https://www.expedia.com/Tavernier-Hotels-Paradise-Palms-Ocean-Pointe-1206.h107445689.Hotel-Information)

![Property grounds](https://images.trvl-media.com/lodging/69000000/68220000/68218400/68218360/58925d59.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![TV](https://images.trvl-media.com/lodging/69000000/68220000/68218400/68218360/5114d9fe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/69000000/68220000/68218400/68218360/9a6a9f91.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/69000000/68220000/68218400/68218360/fe9cce51.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Boho Style Florida Keys Condo Ocean Views

[](https://www.expedia.com/Tavernier-Hotels-Boho-Style-Florida-Keys-Condo-Ocean-Views.h68218360.Hotel-Information)

Tavernier

9.8/10

Exceptional

(44 reviews)

"Would stay there again."

![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg)

jamie g.

$502 nightly

$558 total

Mar 9 - Mar 10

Total with taxes and fees

[](https://www.expedia.com/Tavernier-Hotels-Boho-Style-Florida-Keys-Condo-Ocean-Views.h68218360.Hotel-Information)

![Smart TV](https://images.trvl-media.com/lodging/40000000/39860000/39854400/39854350/119dae30.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Marina](https://images.trvl-media.com/lodging/40000000/39860000/39854400/39854350/5c177f3d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor dining](https://images.trvl-media.com/lodging/40000000/39860000/39854400/39854350/2824ed80.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Marina](https://images.trvl-media.com/lodging/40000000/39860000/39854400/39854350/4e101806.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

###  Waterfront Pool, Beach, Dock, Kayaks

[](https://www.expedia.com/Key-Largo-Hotels-Waterfront-Pool.h39854350.Hotel-Information)

Key Largo

9.8/10

Exceptional

(80 reviews)

"Had a great time property was exactly as described. Would stay again."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Michael S.

$589 nightly

$654 total

Mar 11 - Mar 12

Total with taxes and fees

[](https://www.expedia.com/Key-Largo-Hotels-Waterfront-Pool.h39854350.Hotel-Information)

![Property grounds](https://images.trvl-media.com/lodging/112000000/111090000/111087200/111087158/a19d86d6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/112000000/111090000/111087200/111087158/8d64699e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Pool](https://images.trvl-media.com/lodging/112000000/111090000/111087200/111087158/36ffc601.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/112000000/111090000/111087200/111087158/56f86889.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Happy in the Keys Tiny Home-in Key Largo. 

[](https://www.expedia.com/Key-Largo-Hotels-Charming-3-Bedroom-Tiny-Home-In-Peaceful-Key-Largo-Retreat.h111087158.Hotel-Information)

Key Largo

10/10

Exceptional

(12 reviews)

"It was a lovely place, very clean and comfortable. Will be definitely be coming back. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Carol

$452 nightly

$502 total

Mar 9 - Mar 10

Total with taxes and fees

[](https://www.expedia.com/Key-Largo-Hotels-Charming-3-Bedroom-Tiny-Home-In-Peaceful-Key-Largo-Retreat.h111087158.Hotel-Information)

![On the beach, beach towels](https://images.trvl-media.com/lodging/123000000/122340000/122335800/122335752/bee402e7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/123000000/122340000/122335800/122335752/18554352.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Marina](https://images.trvl-media.com/lodging/123000000/122340000/122335800/122335752/9c453f13.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/123000000/122340000/122335800/122335752/793c44a0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Beachfront Retreat w Pool, Boat Ramp & Dock Rental

[](https://www.expedia.com/Key-Largo-Hotels-Beachfront-Retreat-W-Pool.h122335752.Hotel-Information)

Key Largo

10/10

Exceptional

(6 reviews)

$421 nightly

$468 total

Mar 2 - Mar 3

Total with taxes and fees

[](https://www.expedia.com/Key-Largo-Hotels-Beachfront-Retreat-W-Pool.h122335752.Hotel-Information)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/33000000/32800000/32791200/32791186/03c452e7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/33000000/32800000/32791200/32791186/dd3c2d84.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/33000000/32800000/32791200/32791186/ce81a54b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/33000000/32800000/32791200/32791186/dcaa469a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Fla Keys Luxury Houseboat, Prime Location-Steps to Fun, Food & Water Adventures

[](https://www.expedia.com/Tavernier-Hotels-Florida-Keys-Luxury-Houseboat.h32791186.Hotel-Information)

Tavernier

9.8/10

Exceptional

(213 reviews)

"Absolutely wonderful property in every way!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Christopher K.

$563 nightly

$625 total

Mar 11 - Mar 12

Total with taxes and fees

[](https://www.expedia.com/Tavernier-Hotels-Florida-Keys-Luxury-Houseboat.h32791186.Hotel-Information)

![Marina](https://images.trvl-media.com/lodging/70000000/69980000/69971900/69971899/f997cbd9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool](https://images.trvl-media.com/lodging/70000000/69980000/69971900/69971899/6ef2d3fe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/70000000/69980000/69971900/69971899/d748da89.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Marina](https://images.trvl-media.com/lodging/70000000/69980000/69971900/69971899/fb671c36.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### ARE YOU READY TO SPEND YOUR BEST HOLIDAYS AT SEA ???

[](https://www.expedia.com/Key-Largo-Hotels-Vrbo-Property.h69971899.Hotel-Information)

Key Largo

6.6/10

(21 reviews)

"Small cozy great location, but it’s not a clean I got charged for a cleaning fee it does not look like it cleaned up "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Nora A.

$255 nightly

$284 total

Feb 26 - Feb 27

Total with taxes and fees

[](https://www.expedia.com/Key-Largo-Hotels-Vrbo-Property.h69971899.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

[View all properties](https://expedia.com/Hotel-Search?startDate=2026-02-24&endDate=2026-02-25&regionId=553248621532652349&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&openPlayBack=true)

## Find vacation rentals that suit your style

Aparthotels

[](https://www.expedia.com/Hotel-Search?destination=Lignumvitae+Key+Botanical+State+Park%2C+Florida%2C+United+States+of+America&regionId=553248621532652349&latLong=24.903077%2C-80.695302&adults=2&startDate=2026-05-11&d1=2026-05-11&endDate=2026-05-14&d2=2026-05-14&lodging=APART_HOTEL)

Villas

[](https://www.expedia.com/Hotel-Search?destination=Lignumvitae+Key+Botanical+State+Park%2C+Florida%2C+United+States+of+America&regionId=553248621532652349&latLong=24.903077%2C-80.695302&adults=2&startDate=2026-05-11&d1=2026-05-11&endDate=2026-05-14&d2=2026-05-14&lodging=VILLA)

Apartments

[](https://www.expedia.com/Hotel-Search?destination=Lignumvitae+Key+Botanical+State+Park%2C+Florida%2C+United+States+of+America&regionId=553248621532652349&latLong=24.903077%2C-80.695302&adults=2&startDate=2026-05-11&d1=2026-05-11&endDate=2026-05-14&d2=2026-05-14&lodging=APARTMENT)

Condos

[](https://www.expedia.com/Hotel-Search?destination=Lignumvitae+Key+Botanical+State+Park%2C+Florida%2C+United+States+of+America&regionId=553248621532652349&latLong=24.903077%2C-80.695302&adults=2&startDate=2026-05-11&d1=2026-05-11&endDate=2026-05-14&d2=2026-05-14&lodging=CONDO)

Private vacation homes

[](https://www.expedia.com/Hotel-Search?destination=Lignumvitae+Key+Botanical+State+Park%2C+Florida%2C+United+States+of+America&regionId=553248621532652349&latLong=24.903077%2C-80.695302&adults=2&startDate=2026-05-11&d1=2026-05-11&endDate=2026-05-14&d2=2026-05-14&lodging=VACATION_HOME)

Cottages

[](https://www.expedia.com/Hotel-Search?destination=Lignumvitae+Key+Botanical+State+Park%2C+Florida%2C+United+States+of+America&regionId=553248621532652349&latLong=24.903077%2C-80.695302&adults=2&startDate=2026-05-11&d1=2026-05-11&endDate=2026-05-14&d2=2026-05-14&lodging=COTTAGE)

Houseboats

[](https://www.expedia.com/Hotel-Search?destination=Lignumvitae+Key+Botanical+State+Park%2C+Florida%2C+United+States+of+America&regionId=553248621532652349&latLong=24.903077%2C-80.695302&adults=2&startDate=2026-05-11&d1=2026-05-11&endDate=2026-05-14&d2=2026-05-14&lodging=HOUSE_BOAT)

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## Top Lignumvitae Key Botanical State Park Hotel Reviews

![Bayside Inn Key Largo](https://images.trvl-media.com/lodging/1000000/30000/22700/22657/419b7787_y.jpg)

### Bayside Inn Key Largo

10/10 Excellent

"The room was nice and the amenities fabulous. The sunset was awesome too "

[](https://expedia.com/Key-Largo-Hotels-Bayside-Inn-Key-Largo.h22657.Hotel-Information)

![Lime Tree Bay Resort](https://images.trvl-media.com/lodging/1000000/890000/882300/882254/6f2246e8_y.jpg)

### Lime Tree Bay Resort

10/10 Excellent

"Staff very friendly and wecoming. Nice large room, clean. Our 2nd stay there. "

[](https://expedia.com/Long-Key-Hotels-Lime-Tree-Bay-Resort.h882254.Hotel-Information)

![Amara Cay Resort](https://images.trvl-media.com/lodging/1000000/70000/62000/61976/84b50729_y.jpg)

### Amara Cay Resort

10/10 Excellent

"All good, nice bartender inside downstairs, and easy walk to fish and eat "

[](https://expedia.com/Islamorada-Hotels-Amara-Cay-Resort.h61976.Hotel-Information)

![Marina Del Mar Resort and Marina](https://images.trvl-media.com/lodging/1000000/10000/5200/5114/d42f8885_y.jpg)

### Marina Del Mar Resort and Marina

10/10 Excellent

"Was able to get early check in. Room was clean and comfortable although a bit outdated. Staff was fantastic and the onsite restaurant, Skippers, was amazing."

[](https://expedia.com/Key-Largo-Hotels-Marina-Del-Mar-Resort-And-Marina.h5114.Hotel-Information)

![Cheeca Lodge & Spa](https://images.trvl-media.com/lodging/1000000/10000/5800/5780/617c0723_y.jpg)

### Cheeca Lodge & Spa

10/10 Excellent

"Everything about this resort is wonderful. Lots to do for the whole family, great restaurants, and gorgeous areas. We will definitely be going back."

[](https://expedia.com/Islamorada-Hotels-Cheeca-Lodge-Spa.h5780.Hotel-Information)

![Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort](https://images.trvl-media.com/lodging/1000000/20000/11900/11864/d10a018b_y.jpg)

### Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort

10/10 Excellent

"Location cannot be beat and amenities were perfect we can’t wait to go back "

[](https://expedia.com/Islamorada-Hotels-Three-Waters-Resort-And-Marina.h11864.Hotel-Information)

![Chesapeake Beach Resort](https://images.trvl-media.com/lodging/1000000/10000/4200/4170/689f4306_y.jpg)

### Chesapeake Beach Resort

10/10 Excellent

"We loved this place. It’s small and easy to get around. Beautiful setting, watched the sunrise from bed, and the best hotel breakfast we’ve ever had. "

[](https://expedia.com/Islamorada-Hotels-Chesapeake-Beach-Resort.h4170.Hotel-Information)

![Fisher Inn Resort & Marina](https://images.trvl-media.com/lodging/4000000/3280000/3274400/3274374/9ae0ece9_y.jpg)

### Fisher Inn Resort & Marina

10/10 Excellent

"Very nice place !"

[](https://expedia.com/Islamorada-Hotels-Fisher-Inn-Resort-Marina.h3274374.Hotel-Information)

![Rock Reef Resort](https://images.trvl-media.com/lodging/58000000/57190000/57185500/57185414/6ddda999_y.jpg)

### Rock Reef Resort

10/10 Excellent

"The staff are amazing; very friendly and helpful. We loved our stay and plan on coming back! "

[](https://expedia.com/Key-Largo-Hotels-Rock-Reef-Resort.h57185414.Hotel-Information)

## Find out more about Lignumvitae Key Botanical State Park

**Everything you need to know about Lignumvitae Key Botanical State Park vacation rentals**

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Lignumvitae Key Botanical State Park vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Lignumvitae Key Botanical State Park vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

**Lignumvitae Key Botanical State Park vacation rentals: An excellent choice for every season**

Whenever you want to travel, a warm welcome awaits you in Lignumvitae Key Botanical State Park. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Lignumvitae Key Botanical State Park in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $311 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

**How to find incredible deals on Lignumvitae Key Botanical State Park rentals**

At Expedia, we put the best Lignumvitae Key Botanical State Park vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Lignumvitae Key Botanical State Park rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Lignumvitae Key Botanical State Park vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Lignumvitae Key Botanical State Park. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

## Explore a world of travel with Expedia

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- [Vacation Homes in Lignumvitae Key Botanical State Park ](https://expedia.com/Lignumvitae-Key-Botanical-State-Park-Private-Vacation-Homes.d553248621532652349-aaPrivateVacationHomes.Travel-Guide-Accommodation)
- [Condo Rentals in Lignumvitae Key Botanical State Park ](https://expedia.com/Lignumvitae-Key-Botanical-State-Park-Condos.d553248621532652349-aaCondos.Travel-Guide-Accommodation)
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- [Villas in Lignumvitae Key Botanical State Park ](https://expedia.com/Lignumvitae-Key-Botanical-State-Park-Villas.d553248621532652349-aaVillas.Travel-Guide-Accommodation)
- [Cottages in Lignumvitae Key Botanical State Park ](https://expedia.com/Lignumvitae-Key-Botanical-State-Park-Cottages.d553248621532652349-aaCottages.Travel-Guide-Accommodation)
- [Aparthotels in Lignumvitae Key Botanical State Park ](https://expedia.com/Lignumvitae-Key-Botanical-State-Park-Apart-Hotels.d553248621532652349-aaApartHotels.Travel-Guide-Accommodation)
- [Houseboats in Lignumvitae Key Botanical State Park ](https://expedia.com/Lignumvitae-Key-Botanical-State-Park-Houseboats.d553248621532652349-aaHouseboats.Travel-Guide-Accommodation)
- [RV Parks in Lignumvitae Key Botanical State Park ](https://expedia.com/Lignumvitae-Key-Botanical-State-Park-RV-Parks.d553248621532652349-aaRVParks.Travel-Guide-Accommodation)
- [Resorts in Lignumvitae Key Botanical State Park ](https://expedia.com/Lignumvitae-Key-Botanical-State-Park-Resorts.d553248621532652349-aaResorts.Travel-Guide-Accommodation)
- [Motels in Lignumvitae Key Botanical State Park ](https://expedia.com/Lignumvitae-Key-Botanical-State-Park-Motels.d553248621532652349-aaMotels.Travel-Guide-Accommodation)
- [Guest Houses in Lignumvitae Key Botanical State Park ](https://expedia.com/Lignumvitae-Key-Botanical-State-Park-Guest-Houses.d553248621532652349-aaGuestHouses.Travel-Guide-Accommodation)
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Hotels

- [Top Hotels in Lower Matecumbe Key](https://expedia.com/Lower-Matecumbe-Key-Hotels.d553248635975749077.Travel-Guide-Hotels)
- [Lido Key Oceanfront Hotels](https://expedia.com/Lido-Key-Hotels-Oceanfront-Hotels.0-0-d6138897-tOceanfrontHotels.Travel-Guide-Filter-Hotels)
- [Hurricane Monument hotels](https://expedia.com/Hurricane-Monument-Hotels.0-l6063543-0.Travel-Guide-Filter-Hotels)
- [Amelia Island Beach Hotels](https://expedia.com/Amelia-Island-Hotels-Beach-Hotel.0-0-d10814-tBeachHotel.Travel-Guide-Filter-Hotels)
- [Top Hotels in South Tampa](https://expedia.com/South-Tampa-Hotels.d6321582.Travel-Guide-Hotels)
- [Anne's Beach hotels](https://expedia.com/Annes-Beach-Hotels.0-l6282204-0.Travel-Guide-Filter-Hotels)
- [Top Hotels in Honeymoon Island State Park](https://expedia.com/Honeymoon-Island-State-Park-Hotels.d6160046.Travel-Guide-Hotels)
- [Lido Key Beach Hotels](https://expedia.com/Lido-Key-Hotels-Beach-Hotel.0-0-d6138897-tBeachHotel.Travel-Guide-Filter-Hotels)
- [Top Hotels in Bahia Honda Key](https://expedia.com/Bahia-Honda-Key-Hotels.d553248635083902001.Travel-Guide-Hotels)
- [Amelia Island Oceanfront Hotels](https://expedia.com/Amelia-Island-Hotels-Oceanfront-Hotels.0-0-d10814-tOceanfrontHotels.Travel-Guide-Filter-Hotels)
- [Amelia Island All-inclusive Resorts](https://expedia.com/Amelia-Island-Hotels-All-Inclusive-Hotel.0-0-d10814-tAllinclusiveHotel.Travel-Guide-Filter-Hotels)
- [Top Hotels in Amelia Island](https://expedia.com/Amelia-Island-Hotels.d10814.Travel-Guide-Hotels)
- [Top Hotels in Stock Island](https://expedia.com/Stock-Island-Hotels.d180166.Travel-Guide-Hotels)
- [Top Hotels in Manasota Key](https://expedia.com/Manasota-Key-Hotels.d3000431268.Travel-Guide-Hotels)
- [Top Hotels in Sugarloaf Key](https://expedia.com/Sugarloaf-Key-Hotels.d183126.Travel-Guide-Hotels)
- [Florida Keys Brewing Co. hotels](https://expedia.com/Florida-Keys-Brewing-Co-Hotels.0-l553248635997958830-0.Travel-Guide-Filter-Hotels)

Flights

- [Flights to JAX](https://expedia.com/Cheap-Flights-To-Amelia-Island.d10814.Travel-Guide-Flights)

Cars

- [Car rentals in Amelia Island](https://expedia.com/Car-Rentals-In-Amelia-Island.d10814.Car-Rental-Guide)

Activities

- [Things to do in South Tampa](https://expedia.com/Things-To-Do-In-South-Tampa.d6321582.Travel-Guide-Activities)
- [Things to do in Cudjoe Key](https://expedia.com/Things-To-Do-In-Cudjoe-Key.d3000430966.Travel-Guide-Activities)
- [Things to do in Boca Chica Key](https://expedia.com/Things-To-Do-In-Boca-Chica-Key.d553248635083916609.Travel-Guide-Activities)

Packages

- [Amelia Island Getaways](https://expedia.com/Amelia-Island.d10814.Destination-Travel-Guides)
- [Sunset Drive Beach](https://expedia.com/Sunset-Drive-Beach-Matecumbe.d672757825479704576.Vacation-Attraction)
- [Anne's Beach](https://expedia.com/Annes-Beach-Matecumbe.d6282204.Vacation-Attraction)

Vacation Rentals

- [Amelia Island Short Term Rentals](https://expedia.com/Amelia-Island-Vacation-Rentals.d10814.Travel-Guide-VacationRentals)

General

- [Visit Honeymoon Island State Park](https://expedia.com/Honeymoon-Island-State-Park.dx6160046)
- [Visit Shell Island](https://expedia.com/Shell-Island.dx6312110)
- [Visit Sugarloaf Key](https://expedia.com/Sugarloaf-Key.dx183126)
- [Visit Amelia Island](https://expedia.com/Amelia-Island.dx10814)
- [Visit Upper Matecumbe Key](https://expedia.com/Upper-Matecumbe-Key.dx553248635975749648)

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