Title: Lignumvitae Key Botanical State Park Vacation Rentals from $303: Search Short-Term Rentals | Expedia.com [Lignumvitae Key Botanical State Park Travel Guide](https://expedia.com/Lignumvitae-Key-Botanical-State-Park.dx553248621532652349)[Hotels in Lignumvitae Key Botanical State Park](https://expedia.com/Lignumvitae-Key-Botanical-State-Park-Hotels.d553248621532652349.Travel-Guide-Hotels)[Flights to Lignumvitae Key Botanical State Park](https://expedia.com/Cheap-Flights-To-Lignumvitae-Key-Botanical-State-Park.d553248621532652349.Travel-Guide-Flights)[Car Rentals in Lignumvitae Key Botanical State Park](https://expedia.com/Car-Rentals-In-Lignumvitae-Key-Botanical-State-Park.d553248621532652349.Car-Rental-Guide)[Lignumvitae Key Botanical State Park Vacation Packages](https://expedia.com/Lignumvitae-Key-Botanical-State-Park.d553248621532652349.Destination-Travel-Guides) ![3/4 of a mile paddle from islamorada. There are still ruins and one grave with historic markers from the early settlements of Indians, spanish and american ship wreckers. The island is accessible by paddling or boat.](https://images.trvl-media.com/place/10768/cc086a75-d19c-4609-99ea-434de5d33788.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by RVOutlawz ![](https://images.trvl-media.com/place/10768/cc086a75-d19c-4609-99ea-434de5d33788.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light_bundle_and_save.svg) ### Bundle & Save Get more, spend less whenever you see Bundle & Save deals - ![](https://a.travel-assets.com/travel-assets-manager/pictograms-expedia/light__onekey.svg) ### OneKeyCash Earn OneKeyCash on all your eligible bookings - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light_ftc.svg) ### Upfront pricing We are not like the others - we include taxes and fees ## Check prices for these dates In two weeks [Feb 20 - Feb 22](https://www.expedia.com/Hotel-Search?regionId=553248621532652349&startDate=2026-02-20&endDate=2026-02-22&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two months [Apr 3 - Apr 5](https://www.expedia.com/Hotel-Search?regionId=553248621532652349&startDate=2026-04-03&endDate=2026-04-05&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In three months [May 1 - May 3](https://www.expedia.com/Hotel-Search?regionId=553248621532652349&startDate=2026-05-01&endDate=2026-05-03&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In four months [May 29 - May 31](https://www.expedia.com/Hotel-Search?regionId=553248621532652349&startDate=2026-05-29&endDate=2026-05-31&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Lignumvitae Key Botanical State Park vacation rentals ![25-inch flat-screen TV with digital channels, TV](https://images.trvl-media.com/lodging/92000000/91750000/91743100/91743042/12c235b3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![25-inch flat-screen TV with digital channels, TV](https://images.trvl-media.com/lodging/92000000/91750000/91743100/91743042/92a650b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/92000000/91750000/91743100/91743042/13368841.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, individually decorated, free WiFi, bed sheets](https://images.trvl-media.com/lodging/92000000/91750000/91743100/91743042/b0169681.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Treasure Harbor [](https://www.expedia.com/Islamorada-Hotels-Treasure-Harbor.h91743042.Hotel-Information) Islamorada 9.0/10 Wonderful (129 reviews) "Very peaceful and comfortable stay! Dallas and Hannah were amazing hosts! Thank you so much !" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Nick $270 nightly $304 total Feb 8 - Feb 9 Total with taxes and fees [](https://www.expedia.com/Islamorada-Hotels-Treasure-Harbor.h91743042.Hotel-Information) ![Beach nearby](https://images.trvl-media.com/lodging/75000000/74060000/74058200/74058185/87fe04a0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/75000000/74060000/74058200/74058185/04bfb26d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Marina](https://images.trvl-media.com/lodging/75000000/74060000/74058200/74058185/70d4104f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/75000000/74060000/74058200/74058185/d4b08acb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Paradise in Key Largo, FL [](https://www.expedia.com/Key-Largo-Hotels-Paradise-In-Key-Largo.h74058185.Hotel-Information) Key Largo 9.6/10 Exceptional (64 reviews) "Everything was perfect. I will be a repeat customer for sure. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Carlos O. [](https://www.expedia.com/Key-Largo-Hotels-Paradise-In-Key-Largo.h74058185.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/91000000/90530000/90524700/90524666/83b3602f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/91000000/90530000/90524700/90524666/96b65caf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/91000000/90530000/90524700/90524666/94e72557.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/91000000/90530000/90524700/90524666/b33bbeb4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Florida Keys Getaway - Slps 4 - Ocean View [](https://www.expedia.com/Tavernier-Hotels-Florida-Keys-Getaway-Slps-4-Ocean-View.h90524666.Hotel-Information) Tavernier 9.6/10 Exceptional (20 reviews) "Everything was just as described in the condo listing. We enjoyed the pool and hot tub. Wonderful location to explore the Keys. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Michele G. $319 nightly $354 total Feb 9 - Feb 10 Total with taxes and fees [](https://www.expedia.com/Tavernier-Hotels-Florida-Keys-Getaway-Slps-4-Ocean-View.h90524666.Hotel-Information) ![Beach](https://images.trvl-media.com/lodging/100000000/99380000/99379100/99379050/fec364af.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Marina](https://images.trvl-media.com/lodging/100000000/99380000/99379100/99379050/0571d5ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/100000000/99380000/99379100/99379050/58ae0676.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/100000000/99380000/99379100/99379050/818a355d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### RV by the Sea - Glamping in the Keys - Sleeps 6 [](https://www.expedia.com/Key-Largo-Hotels-RV-By-The-Sea-Glamping-In-The-Keys-Sleeps-6.h99379050.Hotel-Information) Key Largo 9.0/10 Wonderful (21 reviews) "The camper was clean and comfortable. The extras for the beach were great." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) SUSAN C. $251 nightly $280 total Feb 8 - Feb 9 Total with taxes and fees [](https://www.expedia.com/Key-Largo-Hotels-RV-By-The-Sea-Glamping-In-The-Keys-Sleeps-6.h99379050.Hotel-Information) ![Marina](https://images.trvl-media.com/lodging/97000000/96480000/96473300/96473229/w905h683x60y0-10596317.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/97000000/96480000/96473300/96473229/w905h683x60y0-23f3304c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, in-room safe, desk, bed sheets](https://images.trvl-media.com/lodging/97000000/96480000/96473300/96473229/w905h683x60y0-853e5b0d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/97000000/96480000/96473300/96473229/w903h683x60y0-ed597f77.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Island Sanctuary Islamorada [](https://www.expedia.com/Tavernier-Hotels-Island-Sanctuary-Islamorada.h96473229.Hotel-Information) Tavernier 9.8/10 Exceptional (15 reviews) "It exceeded our expectations, and we are so glad we found this location!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jenn H. $382 nightly $423 total Feb 9 - Feb 10 Total with taxes and fees [](https://www.expedia.com/Tavernier-Hotels-Island-Sanctuary-Islamorada.h96473229.Hotel-Information) ![Beach nearby](https://images.trvl-media.com/lodging/78000000/77940000/77937700/77937661/076d9453.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/78000000/77940000/77937700/77937661/587442a1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/78000000/77940000/77937700/77937661/2a8b327f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/78000000/77940000/77937700/77937661/93009341.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Paradise in Key Largo Florida 2 [](https://www.expedia.com/Key-Largo-Hotels-Paradise-In-Key-Largo-Florida.h77937661.Hotel-Information) Key Largo 9.8/10 Exceptional (41 reviews) "The cleanliness, the availability, the comfort. Everything was perfect in fact. Vz are planning on contacting the owner and tomorrow maybe arrange another rental on that property. It was in the perfect spot walking distance to the pool. Everything was readily available. Everything that they advertised was actually above and beyond. Our expectations can't say enough. Good about it was a perfect vacation. Thank you" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Steve V. $389 nightly $432 total Mar 9 - Mar 10 Total with taxes and fees [](https://www.expedia.com/Key-Largo-Hotels-Paradise-In-Key-Largo-Florida.h77937661.Hotel-Information) ![Pool](https://images.trvl-media.com/lodging/64000000/63120000/63112600/63112538/82e6e9b1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/64000000/63120000/63112600/63112538/0464ff2e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV](https://images.trvl-media.com/lodging/64000000/63120000/63112600/63112538/94f309cc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Beach nearby, sun loungers, beach towels](https://images.trvl-media.com/lodging/64000000/63120000/63112600/63112538/9d4d58bb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Amazing Ocean view condo [](https://www.expedia.com/Tavernier-Hotels-Amazing-Ocean-View-Condo.h63112538.Hotel-Information) Tavernier 9.6/10 Exceptional (43 reviews) "Exceeded expectations, exceptionally clean, great for kids (they loved the pool), perfect for our Keys trip" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Natalie M. $381 nightly $423 total Mar 1 - Mar 2 Total with taxes and fees [](https://www.expedia.com/Tavernier-Hotels-Amazing-Ocean-View-Condo.h63112538.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/102000000/101240000/101232100/101232074/0864a30f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, stovetop, coffee/tea maker](https://images.trvl-media.com/lodging/102000000/101240000/101232100/101232074/d41b15fa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/102000000/101240000/101232100/101232074/898c467c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pool](https://images.trvl-media.com/lodging/102000000/101240000/101232100/101232074/dea19358.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cozy place in Calusa Key Largo [](https://www.expedia.com/Key-Largo-Hotels-Cozy-Place-In-Calusa-Key-Largo.h101232074.Hotel-Information) Key Largo 9.0/10 Wonderful (14 reviews) "Perfect weekend getaway location." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tex H. $329 nightly $365 total Feb 9 - Feb 10 Total with taxes and fees [](https://www.expedia.com/Key-Largo-Hotels-Cozy-Place-In-Calusa-Key-Largo.h101232074.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/12000000/11950000/11945900/11945889/19240ce2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/12000000/11950000/11945900/11945889/98989626.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![On the beach, beach towels](https://images.trvl-media.com/lodging/12000000/11950000/11945900/11945889/4550dbd5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Economy Room | 1 bedroom, free WiFi](https://images.trvl-media.com/lodging/12000000/11950000/11945900/11945889/f0ed1fc9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Breezy Palms Resort [](https://www.expedia.com/Islamorada-Hotels-Breezy-Palms-Resort.h11945889.Hotel-Information) Matecumbe 8.8/10 Excellent (616 reviews) "Friendly staff, beautiful peaceful beach, great room with a big comfy bed and all that you might need. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Alexander $269 nightly $303 total Feb 8 - Feb 9 Total with taxes and fees [](https://www.expedia.com/Islamorada-Hotels-Breezy-Palms-Resort.h11945889.Hotel-Information) ![On the beach, beach towels](https://images.trvl-media.com/lodging/123000000/122340000/122335800/122335752/bee402e7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/123000000/122340000/122335800/122335752/2cbe3220.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/123000000/122340000/122335800/122335752/793c44a0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/123000000/122340000/122335800/122335752/18554352.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Beachfront Retreat w Pool, Boat Ramp & Dock Rental [](https://www.expedia.com/Key-Largo-Hotels-Beachfront-Retreat-W-Pool.h122335752.Hotel-Information) Key Largo 10/10 Exceptional (6 reviews) $421 nightly $467 total Feb 10 - Feb 11 Total with taxes and fees [](https://www.expedia.com/Key-Largo-Hotels-Beachfront-Retreat-W-Pool.h122335752.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/109000000/108750000/108743400/108743380/dd2c750f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![55-inch Smart TV with digital channels, books](https://images.trvl-media.com/lodging/109000000/108750000/108743400/108743380/96d842c8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, premium bedding, individually furnished, blackout drapes](https://images.trvl-media.com/lodging/109000000/108750000/108743400/108743380/dc4f4949.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/109000000/108750000/108743400/108743380/ab2c2d1e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Premium Floating Bungalow by Stay Ombi [](https://www.expedia.com/Key-Largo-Hotels-Premium-Floating-Bungalow-By-Stay-Ombi.h108743380.Hotel-Information) Key Largo 10/10 Exceptional (1 review) $920 nightly $1,035 total Feb 11 - Feb 12 Total with taxes and fees [](https://www.expedia.com/Key-Largo-Hotels-Premium-Floating-Bungalow-By-Stay-Ombi.h108743380.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/112000000/111090000/111087200/111087158/a19d86d6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, fireplace](https://images.trvl-media.com/lodging/112000000/111090000/111087200/111087158/bf4827a1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/112000000/111090000/111087200/111087158/56f86889.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/112000000/111090000/111087200/111087158/8d64699e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Happy in the Keys Tiny Home-in Key Largo. [](https://www.expedia.com/Key-Largo-Hotels-Charming-3-Bedroom-Tiny-Home-In-Peaceful-Key-Largo-Retreat.h111087158.Hotel-Information) Key Largo 10/10 Exceptional (12 reviews) "It was a lovely place, very clean and comfortable. Will be definitely be coming back. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Carol $363 nightly $403 total Feb 9 - Feb 10 Total with taxes and fees [](https://www.expedia.com/Key-Largo-Hotels-Charming-3-Bedroom-Tiny-Home-In-Peaceful-Key-Largo-Retreat.h111087158.Hotel-Information) ![Beach nearby](https://images.trvl-media.com/lodging/88000000/87830000/87824100/87824083/f37f6bd9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/88000000/87830000/87824100/87824083/e8ddccf5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/88000000/87830000/87824100/87824083/661fb6e3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV](https://images.trvl-media.com/lodging/88000000/87830000/87824100/87824083/ff77d497.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Blue Haven Key Largo | Ocean Pointe 1315 [](https://www.expedia.com/Tavernier-Hotels-Blue-Haven-Key-Largo-Ocean-Pointe-1315.h87824083.Hotel-Information) Tavernier 9.6/10 Exceptional (15 reviews) "Loved this condo. Had all the amenities we needed and was super clean and tidy. Will definitely be staying here again. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Rodney B. $470 nightly $512 total Mar 4 - Mar 5 Total with taxes and fees [](https://www.expedia.com/Tavernier-Hotels-Blue-Haven-Key-Largo-Ocean-Pointe-1315.h87824083.Hotel-Information) ![Beach nearby](https://images.trvl-media.com/lodging/79000000/78260000/78256400/78256353/c36020a2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pool](https://images.trvl-media.com/lodging/79000000/78260000/78256400/78256353/3d61193f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/79000000/78260000/78256400/78256353/4b534954.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/79000000/78260000/78256400/78256353/98626db3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Modern and Coastal Ocean Pointe 2307 [](https://www.expedia.com/Tavernier-Hotels-Modern-Coastal-Renovation.h78256353.Hotel-Information) Tavernier 10/10 Exceptional (125 reviews) "We enjoyed our stay!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Halley R. $409 nightly $445 total Feb 8 - Feb 9 Total with taxes and fees [](https://www.expedia.com/Tavernier-Hotels-Modern-Coastal-Renovation.h78256353.Hotel-Information) ![Smart TV](https://images.trvl-media.com/lodging/100000000/99970000/99961500/99961430/006a1068.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor dining](https://images.trvl-media.com/lodging/100000000/99970000/99961500/99961430/301698a1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/100000000/99970000/99961500/99961430/078f0b06.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/100000000/99970000/99961500/99961430/b3fdbd21.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Charming Home in Key Largo [](https://www.expedia.com/Key-Largo-Hotels-Charming-Home-In-Key-Largo.h99961430.Hotel-Information) Key Largo 9.8/10 Exceptional (30 reviews) "Great location. Very clean very nice, stay there again" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mark B. $456 nightly $506 total Feb 12 - Feb 13 Total with taxes and fees [](https://www.expedia.com/Key-Largo-Hotels-Charming-Home-In-Key-Largo.h99961430.Hotel-Information) ![Beach towels](https://images.trvl-media.com/lodging/91000000/90180000/90174100/90174063/8b761761.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Marina](https://images.trvl-media.com/lodging/91000000/90180000/90174100/90174063/7d3c5406.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV](https://images.trvl-media.com/lodging/91000000/90180000/90174100/90174063/c885e15a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV](https://images.trvl-media.com/lodging/91000000/90180000/90174100/90174063/c67c2f1a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### New Tiny Home- Paddle Boards, Kayaks, Pool, Marina [](https://www.expedia.com/Key-Largo-Hotels-New-Tiny-Home-Paddle-Boards.h90174063.Hotel-Information) Key Largo 9.6/10 Exceptional (88 reviews) "Great location! Super quiet and relaxing area! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Devin H. $491 nightly $545 total Feb 26 - Feb 27 Total with taxes and fees [](https://www.expedia.com/Key-Largo-Hotels-New-Tiny-Home-Paddle-Boards.h90174063.Hotel-Information) ![Beach nearby](https://images.trvl-media.com/lodging/79000000/78260000/78256400/78256364/bc4eb34c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV](https://images.trvl-media.com/lodging/79000000/78260000/78256400/78256364/c4ba6430.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/79000000/78260000/78256400/78256364/52ff82ed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/79000000/78260000/78256400/78256364/96107825.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Lazy Daze Double King Suite Ocean Pointe 2310 [](https://www.expedia.com/Tavernier-Hotels-Lazy-Daze-Double-King-Suite-Ocean-Pointe-2310.h78256364.Hotel-Information) Tavernier 9.8/10 Exceptional (26 reviews) "Everything was exceptionally nice. Would definitely book again." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sharon $547 nightly $600 total Mar 6 - Mar 7 Total with taxes and fees [](https://www.expedia.com/Tavernier-Hotels-Lazy-Daze-Double-King-Suite-Ocean-Pointe-2310.h78256364.Hotel-Information) ![Marina](https://images.trvl-media.com/lodging/70000000/69980000/69971900/69971899/f997cbd9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Marina](https://images.trvl-media.com/lodging/70000000/69980000/69971900/69971899/fb671c36.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV](https://images.trvl-media.com/lodging/70000000/69980000/69971900/69971899/7a4e1384.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/70000000/69980000/69971900/69971899/d748da89.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### ARE YOU READY TO SPEND YOUR BEST HOLIDAYS AT SEA ??? [](https://www.expedia.com/Key-Largo-Hotels-Vrbo-Property.h69971899.Hotel-Information) Key Largo 6.6/10 (21 reviews) "Small cozy great location, but it’s not a clean I got charged for a cleaning fee it does not look like it cleaned up " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Nora A. $261 nightly $290 total Feb 26 - Feb 27 Total with taxes and fees [](https://www.expedia.com/Key-Largo-Hotels-Vrbo-Property.h69971899.Hotel-Information) ![Beach nearby](https://images.trvl-media.com/lodging/108000000/107450000/107445700/107445689/55a120e1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/108000000/107450000/107445700/107445689/ae7ae6fd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Marina](https://images.trvl-media.com/lodging/108000000/107450000/107445700/107445689/2bdc7822.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/108000000/107450000/107445700/107445689/106bc6f7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Paradise Palms 2 Bedroom Condo Ocean Pointe 1206 [](https://www.expedia.com/Tavernier-Hotels-Paradise-Palms-Ocean-Pointe-1206.h107445689.Hotel-Information) Tavernier 9.8/10 Exceptional (6 reviews) "Thanks for your great hospitality." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) richard $473 nightly $515 total Mar 4 - Mar 5 Total with taxes and fees [](https://www.expedia.com/Tavernier-Hotels-Paradise-Palms-Ocean-Pointe-1206.h107445689.Hotel-Information) ![Beach nearby](https://images.trvl-media.com/lodging/79000000/78260000/78256400/78256355/73768933.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pool](https://images.trvl-media.com/lodging/79000000/78260000/78256400/78256355/42235c88.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/79000000/78260000/78256400/78256355/1b555397.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/79000000/78260000/78256400/78256355/825b25d7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Starfish Seas Ocean Pointe 1302 King/Queen 2BA 2BR [](https://www.expedia.com/Tavernier-Hotels-Starfish-Seas-At-Ocean-Pointe-Suites-Unit-1302.h78256355.Hotel-Information) Tavernier 9.8/10 Exceptional (26 reviews) "Accommodation and location are excellent! Listing is accurate and the resort amenities are very enjoyable after a day out exploring the Keys (or just having at least one whole day at the resort, as we did). " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jenny G. $398 nightly $432 total Feb 8 - Feb 9 Total with taxes and fees [](https://www.expedia.com/Tavernier-Hotels-Starfish-Seas-At-Ocean-Pointe-Suites-Unit-1302.h78256355.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.com/Hotel-Search?startDate=2026-02-21&endDate=2026-02-22®ionId=553248621532652349&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&openPlayBack=true) ## Find vacation rentals that suit your style Apartments [](https://www.expedia.com/Hotel-Search?destination=Lignumvitae+Key+Botanical+State+Park%2C+Florida%2C+United+States+of+America®ionId=553248621532652349&latLong=24.903077%2C-80.695302&adults=2&startDate=2026-05-07&d1=2026-05-07&endDate=2026-05-10&d2=2026-05-10&lodging=APARTMENT) Villas [](https://www.expedia.com/Hotel-Search?destination=Lignumvitae+Key+Botanical+State+Park%2C+Florida%2C+United+States+of+America®ionId=553248621532652349&latLong=24.903077%2C-80.695302&adults=2&startDate=2026-05-07&d1=2026-05-07&endDate=2026-05-10&d2=2026-05-10&lodging=VILLA) Aparthotels [](https://www.expedia.com/Hotel-Search?destination=Lignumvitae+Key+Botanical+State+Park%2C+Florida%2C+United+States+of+America®ionId=553248621532652349&latLong=24.903077%2C-80.695302&adults=2&startDate=2026-05-07&d1=2026-05-07&endDate=2026-05-10&d2=2026-05-10&lodging=APART_HOTEL) Cottages [](https://www.expedia.com/Hotel-Search?destination=Lignumvitae+Key+Botanical+State+Park%2C+Florida%2C+United+States+of+America®ionId=553248621532652349&latLong=24.903077%2C-80.695302&adults=2&startDate=2026-05-07&d1=2026-05-07&endDate=2026-05-10&d2=2026-05-10&lodging=COTTAGE) Private vacation homes [](https://www.expedia.com/Hotel-Search?destination=Lignumvitae+Key+Botanical+State+Park%2C+Florida%2C+United+States+of+America®ionId=553248621532652349&latLong=24.903077%2C-80.695302&adults=2&startDate=2026-05-07&d1=2026-05-07&endDate=2026-05-10&d2=2026-05-10&lodging=VACATION_HOME) Condos [](https://www.expedia.com/Hotel-Search?destination=Lignumvitae+Key+Botanical+State+Park%2C+Florida%2C+United+States+of+America®ionId=553248621532652349&latLong=24.903077%2C-80.695302&adults=2&startDate=2026-05-07&d1=2026-05-07&endDate=2026-05-10&d2=2026-05-10&lodging=CONDO) Houseboats [](https://www.expedia.com/Hotel-Search?destination=Lignumvitae+Key+Botanical+State+Park%2C+Florida%2C+United+States+of+America®ionId=553248621532652349&latLong=24.903077%2C-80.695302&adults=2&startDate=2026-05-07&d1=2026-05-07&endDate=2026-05-10&d2=2026-05-10&lodging=HOUSE_BOAT) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.com/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FLignumvitae-Key-Botanical-State-Park-Vacation-Rentals.d553248621532652349.Travel-Guide-VacationRentals)[ Sign up, it's free ](https://expedia.com/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FLignumvitae-Key-Botanical-State-Park-Vacation-Rentals.d553248621532652349.Travel-Guide-VacationRentals) ## Top Lignumvitae Key Botanical State Park Hotel Reviews ![Amara Cay Resort](https://images.trvl-media.com/lodging/1000000/70000/62000/61976/84b50729_y.jpg) ### Amara Cay Resort 10/10 Excellent "All good, nice bartender inside downstairs, and easy walk to fish and eat " [](https://expedia.com/Islamorada-Hotels-Amara-Cay-Resort.h61976.Hotel-Information) ![Marina Del Mar Resort and Marina](https://images.trvl-media.com/lodging/1000000/10000/5200/5114/d42f8885_y.jpg) ### Marina Del Mar Resort and Marina 10/10 Excellent "Was able to get early check in. Room was clean and comfortable although a bit outdated. Staff was fantastic and the onsite restaurant, Skippers, was amazing." [](https://expedia.com/Key-Largo-Hotels-Marina-Del-Mar-Resort-And-Marina.h5114.Hotel-Information) ![Cheeca Lodge & Spa](https://images.trvl-media.com/lodging/1000000/10000/5800/5780/617c0723_y.jpg) ### Cheeca Lodge & Spa 10/10 Excellent "Everything about this resort is wonderful. Lots to do for the whole family, great restaurants, and gorgeous areas. We will definitely be going back." [](https://expedia.com/Islamorada-Hotels-Cheeca-Lodge-Spa.h5780.Hotel-Information) ![Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort](https://images.trvl-media.com/lodging/1000000/20000/11900/11864/d10a018b_y.jpg) ### Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort 10/10 Excellent "Location cannot be beat and amenities were perfect we can’t wait to go back " [](https://expedia.com/Islamorada-Hotels-Three-Waters-Resort-And-Marina.h11864.Hotel-Information) ![Chesapeake Beach Resort](https://images.trvl-media.com/lodging/1000000/10000/4200/4170/689f4306_y.jpg) ### Chesapeake Beach Resort 10/10 Excellent "We loved this place. It’s small and easy to get around. Beautiful setting, watched the sunrise from bed, and the best hotel breakfast we’ve ever had. " [](https://expedia.com/Islamorada-Hotels-Chesapeake-Beach-Resort.h4170.Hotel-Information) ![Fisher Inn Resort & Marina](https://images.trvl-media.com/lodging/4000000/3280000/3274400/3274374/9ae0ece9_y.jpg) ### Fisher Inn Resort & Marina 10/10 Excellent "Very nice place !" [](https://expedia.com/Islamorada-Hotels-Fisher-Inn-Resort-Marina.h3274374.Hotel-Information) ![Lime Tree Bay Resort](https://images.trvl-media.com/lodging/1000000/890000/882300/882254/6f2246e8_y.jpg) ### Lime Tree Bay Resort 10/10 Excellent "The unit was right on the water. We had everything we needed in our room. The restaurant behind the resort had great food. " [](https://expedia.com/Long-Key-Hotels-Lime-Tree-Bay-Resort.h882254.Hotel-Information) ![Bayside Inn Key Largo](https://images.trvl-media.com/lodging/1000000/30000/22700/22657/419b7787_y.jpg) ### Bayside Inn Key Largo 10/10 Excellent "The staff was amazing, the rooms were clean, the price was great, and the location can’t be beat! It is right next to Snook’s Bayside Restaurant!! " [](https://expedia.com/Key-Largo-Hotels-Bayside-Inn-Key-Largo.h22657.Hotel-Information) ![Baker's Cay Resort Key Largo, Curio Collection by Hilton](https://images.trvl-media.com/lodging/1000000/20000/14100/14042/bbdba544_y.jpg) ### Baker's Cay Resort Key Largo, Curio Collection by Hilton 10/10 Excellent "Clean room and the view was spectacular " [](https://expedia.com/Key-Largo-Hotels-Bakers-Cay-Resort-Key-Largo.h14042.Hotel-Information) ## Find out more about Lignumvitae Key Botanical State Park **Everything you need to know about Lignumvitae Key Botanical State Park vacation rentals** Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Lignumvitae Key Botanical State Park vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on. There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Lignumvitae Key Botanical State Park vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search. **Lignumvitae Key Botanical State Park vacation rentals: An excellent choice for every season** Whenever you want to travel, a warm welcome awaits you in Lignumvitae Key Botanical State Park. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Lignumvitae Key Botanical State Park in high season. Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $303 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals! **How to find incredible deals on Lignumvitae Key Botanical State Park rentals** At Expedia, we put the best Lignumvitae Key Botanical State Park vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia. To find some top Lignumvitae Key Botanical State Park rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Lignumvitae Key Botanical State Park vacation. If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Lignumvitae Key Botanical State Park. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence. ## Explore a world of travel with Expedia - Trending destinations on Expedia.com - All accommodation types in Lignumvitae Key Botanical State Park ### Trending destinations on Expedia.com - [Destin Vacation Rentals ](https://www.expedia.com/Destin-Vacation-Rentals.d6906.Travel-Guide-VacationRentals) - [Panama City Vacation Rentals ](https://www.expedia.com/Panama-City-Beach-Vacation-Rentals.d8021.Travel-Guide-VacationRentals) - [Hilton Head Vacation Rentals ](https://www.expedia.com/Hilton-Head-Island-Vacation-Rentals.d601684.Travel-Guide-VacationRentals) - [Gulf Shores Vacation Rentals ](https://www.expedia.com/Gulf-Shores-Vacation-Rentals.d603078.Travel-Guide-VacationRentals) - [Key West Vacation Rentals ](https://www.expedia.com/Key-West-Vacation-Rentals.d1187.Travel-Guide-VacationRentals) - [Gatlinburg Vacation Rentals ](https://www.expedia.com/Gatlinburg-Vacation-Rentals.d7474.Travel-Guide-VacationRentals) - 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