A forested valley with autumn foliage, a rocky cliff, and a sunset.

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Our top choices for Southern Illinois hotels

1. Comfort Suites Mount Vernon

Comfort Suites Mount Vernon
Mount Vernon
United States
James
$118 nightly
$133 total
Oct 18 - Oct 19
Total with taxes and fees
Comfort Suites Mount Vernon

2. Holiday Inn Express & Suites Mount Vernon by IHG

Holiday Inn Express & Suites Mount Vernon by IHG
Mount Vernon
United States
John
$111 nightly
$125 total
Oct 18 - Oct 19
Total with taxes and fees
Holiday Inn Express & Suites Mount Vernon by IHG

3. DoubleTree by Hilton Mt. Vernon

DoubleTree by Hilton Mt. Vernon
Mount Vernon
United States
Richard
$128 nightly
$144 total
Oct 4 - Oct 5
Total with taxes and fees
DoubleTree by Hilton Mt. Vernon

4. Super 8 by Wyndham Mt. Vernon IL

Super 8 by Wyndham Mt. Vernon IL
Mount Vernon
United States
Matthew W,
$73 nightly
$83 total
Sep 20 - Sep 21
Total with taxes and fees
Super 8 by Wyndham Mt. Vernon IL

5. Days Inn by Wyndham Mount Vernon

Days Inn by Wyndham Mount Vernon
Mount Vernon
United States
Asa
$72 nightly
$82 total
Oct 12 - Oct 13
Total with taxes and fees
Days Inn by Wyndham Mount Vernon

6. Quality Inn Mount Vernon, IL

Quality Inn Mount Vernon, IL
Mount Vernon
United States
Matthew
$71 nightly
$81 total
Oct 18 - Oct 19
Total with taxes and fees
Quality Inn Mount Vernon, IL

7. Fairfield Inn & Suites by Marriott Mt. Vernon Rend Lake

Fairfield Inn & Suites by Marriott Mt. Vernon Rend Lake
Mount Vernon
United States
THERESA
$109 nightly
$124 total
Oct 2 - Oct 3
Total with taxes and fees
Fairfield Inn & Suites by Marriott Mt. Vernon Rend Lake

8. Rodeway Inn Mount Vernon, IL

Rodeway Inn Mount Vernon, IL
Mount Vernon
United States
Emil
$61 nightly
$70 total
Sep 20 - Sep 21
Total with taxes and fees
Rodeway Inn Mount Vernon, IL

9. SureStay Hotel by Best Western Whittington Rend Lake

SureStay Hotel by Best Western Whittington Rend Lake
Whittington
United States
MARK
$81 nightly
$90 total
Sep 27 - Sep 28
Total with taxes and fees
SureStay Hotel by Best Western Whittington Rend Lake

10. Royal Inn

Royal Inn
Mount Vernon
United States
Dorisa
$63 nightly
$72 total
Sep 20 - Sep 21
Total with taxes and fees
Royal Inn

11. Americas Best Value Inn Mount Vernon

Americas Best Value Inn Mount Vernon
Mount Vernon
United States
Jim
$73 nightly
$83 total
Sep 19 - Sep 20
Total with taxes and fees
Americas Best Value Inn Mount Vernon

12. Best Western Plus Centralia Hotel & Suites

Best Western Plus Centralia Hotel & Suites
Centralia
United States
Corey
$139 nightly
$156 total
Sep 20 - Sep 21
Total with taxes and fees
Best Western Plus Centralia Hotel & Suites

13. Holiday Inn Express & Suites Salem by IHG

Holiday Inn Express & Suites Salem by IHG
Salem
United States
John
$110 nightly
$123 total
Oct 4 - Oct 5
Total with taxes and fees
Holiday Inn Express & Suites Salem by IHG

14. Country Garden & Suites

Country Garden & Suites
Benton
United States
Lazarina
$69 nightly
$77 total
Oct 15 - Oct 16
Total with taxes and fees
Country Garden & Suites

15. Americas Best Value Inn West Frankfort

Americas Best Value Inn West Frankfort
West Frankfort
United States
Christopher
$64 nightly
$71 total
Sep 19 - Sep 20
Total with taxes and fees
Americas Best Value Inn West Frankfort

16. Fairgrounds Inn

Fairgrounds Inn
Du Quoin
United States
Kasey
$88 nightly
$98 total
Sep 22 - Sep 23
Total with taxes and fees
Fairgrounds Inn

17. Days Inn by Wyndham Salem, Illinois

Days Inn by Wyndham Salem, Illinois
Salem
United States
Lucas
$49 nightly
$54 total
Sep 28 - Sep 29
Total with taxes and fees
Days Inn by Wyndham Salem, Illinois

18. Quality Inn & Suites Salem near I-57

Quality Inn & Suites Salem near I-57
Salem
United States
Tammy
$74 nightly
$81 total
Oct 9 - Oct 10
Total with taxes and fees
Quality Inn & Suites Salem near I-57

19. Super 8 by Wyndham Du Quoin

Super 8 by Wyndham Du Quoin
Du Quoin
United States
Wendy
$84 nightly
$93 total
Oct 7 - Oct 8
Total with taxes and fees
Super 8 by Wyndham Du Quoin

20. centralia motel

centralia motel
Centralia
United States
Charity
$84 nightly
$93 total
Oct 1 - Oct 2
Total with taxes and fees
centralia motel
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Vacation Rentals in Southern Illinois

Cottage

Peaceful Robinson Home w/ Yard, Near Golf Courses!

Peaceful Robinson Home w/ Yard, Near Golf Courses!
Robinson
Peaceful Robinson Home w/ Yard, Near Golf Courses!
Apartment

Murphysboro Retreat w/ Deck Near Kinkaid Lake!

Murphysboro Retreat w/ Deck Near Kinkaid Lake!
Murphysboro
"This is a very clean and nice apartment within a very close drive to the Kinkaid boat launch. Easy to locate and can fit a car with a boat in tow no problem. This spot was also much more quiet than the campground or RV spots nearby. They have a great porch and a grill and we didn’t bring something for it which made me sad. "
Murphysboro Retreat w/ Deck Near Kinkaid Lake!
Cottage

Country Home Near EIU & Lake Charleston!

Country Home Near EIU & Lake Charleston!
Charleston
"Property was very clean and beautifully decorated in a farmhouse style. Very cozy and comfortable! Came stocked with everything you would need. We had fun at nearby Aikman Wildlife Adventure in Arcola, Kayaking in Lake Charleston, hiking in Fox Ridge State Park a visit to Amish country in Arthur, IL. The kitchen, living and dining room were very spacious! The bathroom was very tiny so if staying with 4 adults - be prepared for this. Also there was a strange odor right outside the front entry...
Country Home Near EIU & Lake Charleston!
Cottage

Illinois Vacation Rental Home: Pets Welcome

Illinois Vacation Rental Home: Pets Welcome
Palestine
Illinois Vacation Rental Home: Pets Welcome
Cottage

Harrisburg Home w/ Private Yard + Screened Porch!

Harrisburg Home w/ Private Yard + Screened Porch!
Harrisburg
"We love how accommodating, helpful and responsive Hollie and Clayton were. The rental had everything we needed and then some. Very clean, cozy and comfortable. We chose this location, because it was close to the different parks and trails we had visited. Thank you, Hollie and Clayton, for being such gracious hosts."
Harrisburg Home w/ Private Yard + Screened Porch!
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Stay near popular Southern Illinois attractions

A rocky landscape with a sunset in the background.

Garden of the Gods Recreation Area

9.8/10 (63 reviews)
See for yourself why Harrisburg’s unearthly sandstone formations, tucked within lush Shawnee National Forest, earn their ethereal name.
See properties
A rock formation with a tree growing in the center.
Photo by Southernmost Illinois Tourism Bureau

Giant City State Park

9.2/10 (141 reviews)
Walk amid mystical woodland, admire geological wonders, go horseback riding and camp in the wilderness in the spectacular countryside of Southwest Illinois.
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World Wide Technology Raceway

9.0/10 (2 reviews)
Catch an event at World Wide Technology Raceway during your trip to St. Louis. Attend a sporting event or simply enjoy the top-notch restaurants while you're in the area.
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O'Fallon Family Sports Park

8.6/10 (137 reviews)
This sports complex features premium turf fields, splash pads, and fishing ponds in a family-friendly setting. Watch tournaments or enjoy the scenic walking trail that winds around natural areas.
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Harrah's Metropolis

8.0/10 (310 reviews)
This riverside casino offers over 600 slot machines and 17 table games along the scenic Ohio River. Join the rewards program to maximize your experience while enjoying Southern classics at the on-site restaurants.
See properties

Learn more about Southern Illinois

Discover the culture and history of this region shaped by indigenous and pioneering communities and spend time in its peaceful, picturesque landscapes.

See all hotels in Southern Illinois
A forested valley with autumn foliage, a rocky cliff, and a sunset.
Photo by Southernmost Illinois Tourism Bureau

Top Southern Illinois Hotel Reviews

Motel 6 Caseyville, IL - Caseyville Il

Motel 6 Caseyville, IL - Caseyville Il

10/10 Excellent
"Clean"
Marisa 1-night trip
Posted 2 hours ago
Motel 6 Caseyville, IL - Caseyville Il
Ramada by Wyndham Effingham

Ramada by Wyndham Effingham

8/10 Good
"Our room was very clean and comfortable. We were quite weary from our trip and were so thankful for stumbling upon this hotel. We book our rooms "on the fly" and sometimes that means we get less than desirable deals. That was not the case here. Next time we're in the area, we would be happy to stay at this hotel again."
Randy 1-night trip
Posted 3 hours ago
Ramada by Wyndham Effingham
Walker's Bluff Casino Resort

Walker's Bluff Casino Resort

8/10 Good
"AC wasn’t working right but still not to bad."
Earl 2-night trip
Posted 9 hours ago
Walker's Bluff Casino Resort
Country Inn & Suites by Radisson, Effingham, IL

Country Inn & Suites by Radisson, Effingham, IL

10/10 Excellent
"This place was very clean. The bed was super comfortable and the sheets were silky soft."
Judy 1-night trip
Posted 16 hours ago
Country Inn & Suites by Radisson, Effingham, IL
Drury Inn & Suites St. Louis Fairview Heights

Drury Inn & Suites St. Louis Fairview Heights

10/10 Excellent
"Clean rooms awesome breakfast and staff"
Roger 1-night trip
Posted 20 hours ago
Drury Inn & Suites St. Louis Fairview Heights
Drury Plaza Hotel Mt. Vernon

Drury Plaza Hotel Mt. Vernon

10/10 Excellent
"Great breakfast and kick back evening meal. Very nice and comfortable."
Dwight 3-night trip
Posted 21 hours ago
Drury Plaza Hotel Mt. Vernon
Comfort Suites Mount Vernon

Comfort Suites Mount Vernon

10/10 Excellent
"Very nice new/updated hotel. Good breakfast. Sausage gravy both days we were there. It’s a good location with several restaurants walkable. The BBQ place across the street was great. My only complaint is the room air conditioning was very loud and had a rattling sound. It kept my wife and me up during the night."
Gregory 2-night trip
Posted 3 days ago
Comfort Suites Mount Vernon

More cheap stays in Southern Illinois

Americas Best Value Inn Collinsville St. Louis

Americas Best Value Inn Collinsville St. Louis

552 Ramada Blvd Collinsville IL
$53 nightly
$61 total
Oct 11 - Oct 12
Total with taxes and fees
Americas Best Value Inn Collinsville St. Louis
Super 8 by Wyndham O'Fallon

Super 8 by Wyndham O'Fallon

1100 Eastgate Dr O'Fallon IL
$54 nightly
$62 total
Oct 13 - Oct 14
Total with taxes and fees
Super 8 by Wyndham O'Fallon
Best Western Delta Inn

Best Western Delta Inn

1509 Hampton Dr Effingham IL
$90 nightly
$100 total
Oct 4 - Oct 5
Total with taxes and fees
9/10 Wonderful! (1,002 reviews)
Best Western Delta Inn
Country Inn & Suites by Radisson, Effingham, IL

Country Inn & Suites by Radisson, Effingham, IL

1200 N Raney Effingham IL
$91 nightly
$101 total
Oct 18 - Oct 19
Total with taxes and fees
8.6/10 Excellent! (1,007 reviews)
Country Inn & Suites by Radisson, Effingham, IL
Comfort Inn Edwardsville - St. Louis

Comfort Inn Edwardsville - St. Louis

3080 S State Route 157 Edwardsville IL
$95 nightly
$109 total
Oct 11 - Oct 12
Total with taxes and fees
Comfort Inn Edwardsville - St. Louis
Baymont by Wyndham Marion

Baymont by Wyndham Marion

2608 W Main St Marion IL
$93 nightly
$112 total
Sep 27 - Sep 28
Total with taxes and fees
8.4/10 Very Good! (1,089 reviews)
Baymont by Wyndham Marion

Hotels in Southern Illinois with star-rating

Find out more about Southern Illinois

Top reasons to visit Southern Illinois

  • Stunning Natural Scenery: Southern Illinois boasts breathtaking landscapes, including the scenic Shawnee Hills and beautiful lakes.
  • Outdoor Adventures: The region offers a variety of outdoor activities, from hiking and camping to fishing and boating.
  • Charming Accommodations: Enjoy a range of lodging options, from luxurious hotels to cozy cabins, catering to all travelers.
  • Family-Friendly Attractions: Explore vibrant fairgrounds and state parks that provide fun for visitors of all ages.
  • Romantic Getaways: Southern Illinois is perfect for couples seeking a peaceful retreat amidst nature's beauty.

Find great hotels near Southern Illinois

Experience the charm of Southern Illinois with a range of hotel accommodations tailored to your needs. From luxurious lodgings to family-friendly motels, you'll find pet-friendly options and quality inns perfect for business travelers and vacationers alike. Explore Carbondale hotels and select luxury hotels that cater to every type of guest, ensuring a comfortable and enjoyable stay in this beautiful region.

  • Drury Plaza Hotel Mt. Vernon: Drury Plaza Hotel Mt. Vernon is a highly-rated 3-star hotel, boasting a remarkable guest rating of 9.6. Situated 6 miles from Southern Illinois, this property is an excellent choice for families, business travelers, and pet owners. Guests appreciate the family-friendly amenities, including free cribs and pet allowances, making it a welcoming environment for all. The hotel features a complimentary breakfast, an indoor pool, and a fitness center, ensuring a comfortable and enjoyable stay. The combination of modern facilities and a warm atmosphere makes Drury Plaza Hotel a top pick for travelers seeking both convenience and comfort.
  • Comfort Suites Mount Vernon: Comfort Suites Mount Vernon is a budget-friendly option with a solid guest rating of 9.0, located 5 miles from Southern Illinois. This hotel is perfect for families, business travelers, and pet lovers alike. Offering amenities like free cribs and window guards for children, it ensures a safe and accommodating stay for families. Guests can enjoy spacious suites and a complimentary breakfast, as well as pet-friendly policies that allow for a hassle-free experience. Comfort Suites stands out for its blend of affordability and practicality, making it a smart choice for budget-conscious travelers.
  • Super 8 by Wyndham Mt. Vernon IL: Super 8 by Wyndham Mt. Vernon IL is a budget-friendly hotel known for its welcoming atmosphere, rated 9.0 by guests. Located 6 miles from Southern Illinois, it caters to families, business travelers, and pet owners. The hotel provides essential amenities such as free cribs, window guards for children, and a first aid kit, ensuring peace of mind for families. With pet-friendly policies and affordable rates, Super 8 offers a convenient stay without compromising on comfort, making it an ideal choice for travelers looking for value.

Where to stay near Southern Illinois

Southern Illinois is a hidden gem for travelers seeking outdoor adventures and romantic getaways. With its scenic Shawnee Hills and charming lakeside cabins, it offers a perfect blend of relaxation and recreation. Explore family-friendly towns and enjoy the friendly atmosphere while discovering the rural beauty of the region. Just a short drive from St. Louis, Southern Illinois promises an unforgettable experience filled with stunning landscapes and welcoming communities.

  • Mount Vernon: Nestled a mere 4 miles from Southern Illinois, Mount Vernon is an inviting city perfect for outdoor enthusiasts and those seeking scenic beauty. With a steady flow of visitors year-round, the peak season arrives in April and from June to July. Travelers flock to Mount Vernon for its romantic atmosphere and access to recreational areas, educational venues, and campgrounds. Nearby attractions include picturesque lakes, lush forests, and the stunning national state park, making it an ideal destination for a nature-filled getaway.
  • Opdyke: Also located 4 miles from Southern Illinois, Opdyke is a charming city with a welcoming vibe. Visitor numbers remain relatively stable throughout the year, with peaks in January to February and August. Known for its outdoor experiences and romantic settings, Opdyke offers a tranquil escape. The city is home to educational institutions and is surrounded by beautiful lakes and a modern college university, providing ample opportunities for exploration and relaxation.
  • Bonnie: Situated 6 miles from Southern Illinois, Bonnie is a delightful city that attracts seasonal visitors, especially in May and from July to August. Known for its outdoor adventures and scenic landscapes, Bonnie offers a romantic getaway for couples and families alike. Visitors can enjoy recreational areas, fairgrounds, and trail access, while local landmarks such as beautiful lakes, a national state park, and a visitor center enhance the experience. Bonnie's charm lies in its blend of nature and community activities, making it a great stop on your Southern Illinois journey.

Things to do in Southern Illinois

Southern Illinois is a perfect destination for outdoor enthusiasts and couples seeking a romantic getaway. With its stunning scenery, visitors can enjoy a variety of activities including recreational areas and campgrounds. It's also an ideal location for hosting weddings and parties, making it a versatile choice for both adventure and celebration. Experience the natural beauty and charm that Southern Illinois has to offer.

Shopping

In Southern Illinois, explore the bustling Carbondale Mall for a variety of stores, or visit the charming shops at the historic Murphysboro Market for unique gifts. Don’t miss the local artisan goods at the Shawnee Hills Wine Trail, perfect for memorable souvenirs.

Recreation

Experience tranquility at the New Life Wellness Spa, where you can indulge in rejuvenating massages and holistic therapies. Explore the nearby Shawnee National Forest for hiking, birdwatching, and connecting with nature, offering a perfect blend of relaxation and outdoor adventure.

Adventure

In Southern Illinois, explore the breathtaking Giant City State Park with its hiking trails and rock formations. Experience the thrill of zip-lining at Shawnee Bluffs Canopy Tour, or embark on a kayaking adventure on the beautiful Cache River, immersing yourself in the area's rich natural beauty.

Nightlife

Explore the vibrant nightlife at The Varsity Center in Carbondale, where you can catch live performances and events. For a laid-back vibe, visit The Cellar, a cozy spot for craft beers and cocktails. Don't miss the lively atmosphere at Pinch Penny Pub, known for its fun games and friendly crowd.

*Distances are measured in a straight line; actual driving distances may vary depending on the route.

Booking tips and Expedia advantages for Southern Illinois

  • The most and least expensive months on average to stay in a hotel: The cheapest months to stay around Southern Illinois are January to February and November, where the prices are slightly lower. This is in comparison to April and June to July, where prices are slightly higher.
  • The most and least expensive days on average to stay in a hotel: The least expensive day to stay around Southern Illinois is Tuesday. The most expensive day to stay around Southern Illinois is Saturday.
  • Find cheap hotels on Expedia: Utilize Expedia's search tool to refine your options based on your budget, desired location, and preferred hotel type. To find the best prices and deals, simply arrange the price filter from lowest to highest.
  • Consider bundling your trip: You can save money by combining your hotel stay in Southern Illinois with your flights and activities through an Expedia package deal.

Find the best attractions near Southern Illinois

Southern Illinois is perfect for outdoor enthusiasts and those seeking romantic getaways, offering stunning scenery and family-friendly experiences. Visitors can explore beautiful lakes, vibrant fairgrounds, and state parks that showcase the region's natural beauty. With a variety of attractions to enjoy, Southern Illinois promises memorable adventures for everyone.

  • Rend Lake: Located 13 miles from Southern Illinois, Rend Lake offers a picturesque setting perfect for outdoor enthusiasts. Enjoy romantic beach vibes, stunning scenery, and a range of activities such as fishing, boating, and picnicking along the shore.
  • Jefferson County Fairgrounds: Just 3 miles away, the Jefferson County Fairgrounds is a lively destination for families. Experience local events, fairs, and community gatherings in a welcoming outdoor environment that fosters fun and togetherness.
  • Wayne Fitzgerrell State Park: Situated 14 miles from Southern Illinois, this national park is an adventurer's paradise. Discover breathtaking views, hiking trails, and various outdoor activities that highlight the natural beauty of the region.

Best time to go to Southern Illinois

The best time to visit Southern Illinois is dependent on what kind of holiday you are seeking. July is its hottest month on average. At this time, visitor numbers are slightly high and weather is mostly sunny with light rain. January is its coolest month on average. At this time, visitor numbers are slightly low and weather is mostly cloudy with light rain.

calendarCalendar MonthtemperatureTemperaturerainPrecipitationmostlyCloudinessoccupationOccupancypricePricing
January30.9°F (-0.6°C)Light RainMostly CloudySlightly LowSlightly Low
February36.9°F (2.7°C)Light RainMostly CloudySlightly LowSlightly Low
March48.0°F (8.9°C)Light RainMostly SunnyAverageAverage
April55.2°F (12.9°C)Light RainMostly SunnySlightly LowSlightly High
May66.7°F (19.3°C)Light RainMostly SunnyAverageAverage
June75.9°F (24.4°C)Light RainMostly SunnySlightly HighSlightly High
July78.8°F (26.0°C)Light RainMostly SunnySlightly HighSlightly High
August77.0°F (25.0°C)Light RainMostly SunnySlightly HighAverage
September71.2°F (21.8°C)Light RainMostly SunnyAverageAverage
October56.7°F (13.7°C)Light RainMostly SunnyAverageAverage
November46.6°F (8.1°C)Light RainMostly SunnyAverageSlightly Low
December39.0°F (3.9°C)Light RainMostly SunnyAverageAverage

The nearest major airports for your trip to Southern Illinois

When visiting Southern Illinois, you can fly into several major airports. St. Louis Lambert International Airport (STL) is 88 miles away, with nearby hotels such as The Ritz-Carlton, St. Louis and Ameristar Casino Resort and Spa, both 7 miles from the airport. Evansville Regional Airport (EVV) is 74 miles away, offering hotel options like DoubleTree by Hilton Evansville, 6 miles from the airport, and Holiday Inn Evansville Airport, just 0.8 miles away. Bloomington-Normal Central Illinois Regional Airport (BMI) is 152 miles from Southern Illinois, with hotels like DoubleTree by Hilton Hotel Bloomington, 3 miles away, and Hyatt Place Bloomington/Normal, 4 miles away.

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