Find hotels in Southern Illinois, IL from $52

  • Upfront pricing

    Our total price for your stay includes taxes and fees
  • Treat yourself

    Save 10% or more on over 100,000 hotels worldwide with Member Prices
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Next weekend
In two weeks

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Southern Illinois hotels

Suite Dreams Hotel

Suite Dreams Hotel
2.0 star property
Mattoon
8.8 out of 10, Excellent, (3 reviews)
"Owners are very nice and take pride in their hotel and it shows!"
United States
Judd
$79 nightly
The price is $89
Jun 22 - Jun 23
Total with taxes and fees
Suite Dreams Hotel

Drury Inn & Suites Marion

Drury Inn & Suites Marion
3.0 star property
Marion
9.4 out of 10, Exceptional, (1,001 reviews)
"Clean room, great breakfast and evening drinks & food. Friendly staff."
United States
Brandy
$99 nightly
The price is $119
Jun 28 - Jun 29
Total with taxes and fees
Drury Inn & Suites Marion

Holiday Inn Effingham by IHG

Holiday Inn Effingham by IHG
3.5 star property
Effingham
9.2 out of 10, Wonderful, (692 reviews)
"Nice hotel. Great location on the Ohio River. Walking distance to the old downtown."
United States
Glenn
$101 nightly
The price is $113
Jul 5 - Jul 6
Total with taxes and fees
Holiday Inn Effingham by IHG

Hampton Inn & Suites Effingham

Hampton Inn & Suites Effingham
2.5 star property
Effingham
9.6 out of 10, Exceptional, (742 reviews)
"Everything about this place was excellent"
United States
Andrew
$124 nightly
The price is $137
Jul 4 - Jul 5
Total with taxes and fees
Hampton Inn & Suites Effingham

Holiday Inn Express & Suites Murphysboro - Carbondale by IHG

Holiday Inn Express & Suites Murphysboro - Carbondale by IHG
2.5 star property
Murphysboro
9.4 out of 10, Exceptional, (551 reviews)
"Great place and folks!! Breakfast was on point, and the staff is very nice and friendly. Will be back!"
United States
Mark
$118 nightly
The price is $131
Jun 28 - Jun 29
Total with taxes and fees
Holiday Inn Express & Suites Murphysboro - Carbondale by IHG

The Principal Hotel

The Principal Hotel
3.5 star property
Columbia
9.6 out of 10, Exceptional, (302 reviews)
"Great hotel and nice staff!"
United States
Michelle
$105 nightly
The price is $116
Jul 9 - Jul 10
Total with taxes and fees
The Principal Hotel

Cobblestone Inn & Suites - Altamont

Cobblestone Inn & Suites - Altamont
2.5 star property
Altamont
9.6 out of 10, Exceptional, (878 reviews)
"The hotel was fabulous!"
United States
Dominic
$94 nightly
The price is $102
Jun 21 - Jun 22
Total with taxes and fees
Cobblestone Inn & Suites - Altamont

Country Inn & Suites by Radisson, Effingham, IL

Country Inn & Suites by Radisson, Effingham, IL
2.5 star property
Effingham
8.8 out of 10, Excellent, (1,001 reviews)
"Wonderful stay. "
United States
Jennifer
$84 nightly
The price is $93
Jul 12 - Jul 13
Total with taxes and fees
Country Inn & Suites by Radisson, Effingham, IL

Home2 Suites By Hilton Effingham

Home2 Suites By Hilton Effingham
3.0 star property
Effingham
9.6 out of 10, Exceptional, (52 reviews)
"It was a very nice hotel."
United States
Anthony
$124 nightly
The price is $139
Jul 4 - Jul 5
Total with taxes and fees
Home2 Suites By Hilton Effingham

Days Inn & Suites by Wyndham Casey

Days Inn & Suites by Wyndham Casey
2.0 star property
Casey
7.6 out of 10, Good, (886 reviews)
"Clean room and great staff!"
United States
Beth
$67 nightly
The price is $74
Jul 19 - Jul 20
Total with taxes and fees
Days Inn & Suites by Wyndham Casey

Fairfield by Marriott Inn & Suites Mattoon

Fairfield by Marriott Inn & Suites Mattoon
2.5 star property
Mattoon
8.4 out of 10, Very Good, (12 reviews)
"The Belgium waffle's were excellent."
United States
Stephen
$143 nightly
The price is $159
Jun 29 - Jun 30
Total with taxes and fees
Fairfield by Marriott Inn & Suites Mattoon

Drury Plaza Hotel Mt. Vernon

Drury Plaza Hotel Mt. Vernon
3.5 star property
Mount Vernon
9.6 out of 10, Exceptional, (1,705 reviews)
"A nice stay"
United States
DAVID
$111 nightly
The price is $125
Jul 12 - Jul 13
Total with taxes and fees
Drury Plaza Hotel Mt. Vernon

SureStay Hotel by Best Western Whittington Rend Lake

SureStay Hotel by Best Western Whittington Rend Lake
2.5 star property
Whittington
8.8 out of 10, Excellent, (982 reviews)
"Staff was friendly room was clean"
United States
Brandon
$85 nightly
The price is $95
Jun 28 - Jun 29
Total with taxes and fees
SureStay Hotel by Best Western Whittington Rend Lake

Ramada by Wyndham Effingham

Ramada by Wyndham Effingham
3.0 star property
Effingham
7.4 out of 10, Good, (1,000 reviews)
"The staff is great, they do a really good job."
United States
Martin
$59 nightly
The price is $66
Jun 28 - Jun 29
Total with taxes and fees
Ramada by Wyndham Effingham

Holiday Inn Express & Suites Vandalia by IHG

Holiday Inn Express & Suites Vandalia by IHG
2.5 star property
Vandalia
8.8 out of 10, Excellent, (832 reviews)
"Easy access fro I70.. Hotel very full but breakfast dining was clean & stocked."
United States
Joyce
$108 nightly
The price is $118
Jun 28 - Jun 29
Total with taxes and fees
Holiday Inn Express & Suites Vandalia by IHG

Comfort Suites Mount Vernon

Comfort Suites Mount Vernon
2.5 star property
Mount Vernon
9.0 out of 10, Wonderful, (1,048 reviews)
"Quick and easy check in, fruendly staff, bed and pillows were super comfy and the breakfast was great. "
United States
Todd
$119 nightly
The price is $134
Jun 21 - Jun 22
Total with taxes and fees
Comfort Suites Mount Vernon

Best Western Delta Inn

Best Western Delta Inn
2.5 star property
Effingham
9.0 out of 10, Wonderful, (1,002 reviews)
"Nice quick stay"
United States
Bri
$97 nightly
The price is $109
Jun 28 - Jun 29
Total with taxes and fees
Best Western Delta Inn

La Quinta Inn & Suites by Wyndham Effingham

La Quinta Inn & Suites by Wyndham Effingham
3.0 star property
Effingham
9.2 out of 10, Wonderful, (1,002 reviews)
"Clean hotel, excellent staff, good breakfast"
United States
Alexis
$101 nightly
The price is $113
Jun 28 - Jun 29
Total with taxes and fees
La Quinta Inn & Suites by Wyndham Effingham

Quality Inn Effingham North

Quality Inn Effingham North
2.5 star property
Effingham
8.4 out of 10, Very Good, (1,002 reviews)
"Nice overnight stay"
United States
Suzanne
$83 nightly
The price is $92
Jun 28 - Jun 29
Total with taxes and fees
Quality Inn Effingham North

Charleston House Bed & Breakfast Inn

Charleston House Bed & Breakfast Inn
4.0 star property
Charleston
10.0 out of 10, Exceptional, (12 reviews)
"The place was fantastic and just what I was looking for. The room was excellent, clean, comfortable. The host was great! Breakfast was delicious! "
United States
Kristy
$82 nightly
The price is $91
Jun 22 - Jun 23
Total with taxes and fees
Charleston House Bed & Breakfast Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in

Stay near popular Southern Illinois attractions

Learn more about Southern Illinois

Discover the culture and history of this region shaped by indigenous and pioneering communities and spend time in its peaceful, picturesque landscapes.

Photo by Southernmost Illinois Tourism Bureau
Open Photo by Southernmost Illinois Tourism Bureau

Top Southern Illinois Hotel Reviews

More cheap stays in Southern Illinois

Hotels in Southern Illinois with star-rating

Find out more about Southern Illinois

Top reasons to visit Southern Illinois

  • Stunning Natural Scenery: Southern Illinois boasts breathtaking landscapes, including the scenic Shawnee Hills and beautiful lakes.
  • Outdoor Adventures: The region offers a variety of outdoor activities, from hiking and camping to fishing and boating.
  • Charming Accommodations: Enjoy a range of lodging options, from luxurious hotels to cozy cabins, catering to all travelers.
  • Family-Friendly Attractions: Explore vibrant fairgrounds and state parks that provide fun for visitors of all ages.
  • Romantic Getaways: Southern Illinois is perfect for couples seeking a peaceful retreat amidst nature's beauty.

Find great hotels near Southern Illinois

Experience the charm of Southern Illinois with a range of hotel accommodations tailored to your needs. From luxurious lodgings to family-friendly motels, you'll find pet-friendly options and quality inns perfect for business travelers and vacationers alike. Explore Carbondale hotels and select luxury hotels that cater to every type of guest, ensuring a comfortable and enjoyable stay in this beautiful region.

  • Drury Plaza Hotel Mt. Vernon: Drury Plaza Hotel Mt. Vernon is a highly-rated 3-star hotel, boasting a remarkable guest rating of 9.6. Situated 6 miles from Southern Illinois, this property is an excellent choice for families, business travelers, and pet owners. Guests appreciate the family-friendly amenities, including free cribs and pet allowances, making it a welcoming environment for all. The hotel features a complimentary breakfast, an indoor pool, and a fitness center, ensuring a comfortable and enjoyable stay. The combination of modern facilities and a warm atmosphere makes Drury Plaza Hotel a top pick for travelers seeking both convenience and comfort.
  • Comfort Suites Mount Vernon: Comfort Suites Mount Vernon is a budget-friendly option with a solid guest rating of 9.0, located 5 miles from Southern Illinois. This hotel is perfect for families, business travelers, and pet lovers alike. Offering amenities like free cribs and window guards for children, it ensures a safe and accommodating stay for families. Guests can enjoy spacious suites and a complimentary breakfast, as well as pet-friendly policies that allow for a hassle-free experience. Comfort Suites stands out for its blend of affordability and practicality, making it a smart choice for budget-conscious travelers.
  • Super 8 by Wyndham Mt. Vernon IL: Super 8 by Wyndham Mt. Vernon IL is a budget-friendly hotel known for its welcoming atmosphere, rated 9.0 by guests. Located 6 miles from Southern Illinois, it caters to families, business travelers, and pet owners. The hotel provides essential amenities such as free cribs, window guards for children, and a first aid kit, ensuring peace of mind for families. With pet-friendly policies and affordable rates, Super 8 offers a convenient stay without compromising on comfort, making it an ideal choice for travelers looking for value.

Where to stay near Southern Illinois

Southern Illinois is a hidden gem for travelers seeking outdoor adventures and romantic getaways. With its scenic Shawnee Hills and charming lakeside cabins, it offers a perfect blend of relaxation and recreation. Explore family-friendly towns and enjoy the friendly atmosphere while discovering the rural beauty of the region. Just a short drive from St. Louis, Southern Illinois promises an unforgettable experience filled with stunning landscapes and welcoming communities.

  • Mount Vernon: Nestled a mere 4 miles from Southern Illinois, Mount Vernon is an inviting city perfect for outdoor enthusiasts and those seeking scenic beauty. With a steady flow of visitors year-round, the peak season arrives in April and from June to July. Travelers flock to Mount Vernon for its romantic atmosphere and access to recreational areas, educational venues, and campgrounds. Nearby attractions include picturesque lakes, lush forests, and the stunning national state park, making it an ideal destination for a nature-filled getaway.
  • Opdyke: Also located 4 miles from Southern Illinois, Opdyke is a charming city with a welcoming vibe. Visitor numbers remain relatively stable throughout the year, with peaks in January to February and August. Known for its outdoor experiences and romantic settings, Opdyke offers a tranquil escape. The city is home to educational institutions and is surrounded by beautiful lakes and a modern college university, providing ample opportunities for exploration and relaxation.
  • Bonnie: Situated 6 miles from Southern Illinois, Bonnie is a delightful city that attracts seasonal visitors, especially in May and from July to August. Known for its outdoor adventures and scenic landscapes, Bonnie offers a romantic getaway for couples and families alike. Visitors can enjoy recreational areas, fairgrounds, and trail access, while local landmarks such as beautiful lakes, a national state park, and a visitor center enhance the experience. Bonnie's charm lies in its blend of nature and community activities, making it a great stop on your Southern Illinois journey.

Things to do in Southern Illinois

Southern Illinois is a perfect destination for outdoor enthusiasts and couples seeking a romantic getaway. With its stunning scenery, visitors can enjoy a variety of activities including recreational areas and campgrounds. It's also an ideal location for hosting weddings and parties, making it a versatile choice for both adventure and celebration. Experience the natural beauty and charm that Southern Illinois has to offer.

Shopping

In Southern Illinois, explore the bustling Carbondale Mall for a variety of stores, or visit the charming shops at the historic Murphysboro Market for unique gifts. Don’t miss the local artisan goods at the Shawnee Hills Wine Trail, perfect for memorable souvenirs.

Recreation

Experience tranquility at the New Life Wellness Spa, where you can indulge in rejuvenating massages and holistic therapies. Explore the nearby Shawnee National Forest for hiking, birdwatching, and connecting with nature, offering a perfect blend of relaxation and outdoor adventure.

Adventure

In Southern Illinois, explore the breathtaking Giant City State Park with its hiking trails and rock formations. Experience the thrill of zip-lining at Shawnee Bluffs Canopy Tour, or embark on a kayaking adventure on the beautiful Cache River, immersing yourself in the area's rich natural beauty.

Nightlife

Explore the vibrant nightlife at The Varsity Center in Carbondale, where you can catch live performances and events. For a laid-back vibe, visit The Cellar, a cozy spot for craft beers and cocktails. Don't miss the lively atmosphere at Pinch Penny Pub, known for its fun games and friendly crowd.

*Distances are measured in a straight line; actual driving distances may vary depending on the route.

Booking tips and Expedia advantages for Southern Illinois

  • The most and least expensive months on average to stay in a hotel: The cheapest months to stay around Southern Illinois are January to February and November, where the prices are slightly lower. This is in comparison to April and June to July, where prices are slightly higher.
  • The most and least expensive days on average to stay in a hotel: The least expensive day to stay around Southern Illinois is Tuesday. The most expensive day to stay around Southern Illinois is Saturday.
  • Find cheap hotels on Expedia: Utilize Expedia's search tool to refine your options based on your budget, desired location, and preferred hotel type. To find the best prices and deals, simply arrange the price filter from lowest to highest.
  • Consider bundling your trip: You can save money by combining your hotel stay in Southern Illinois with your flights and activities through an Expedia package deal.

Find the best attractions near Southern Illinois

Southern Illinois is perfect for outdoor enthusiasts and those seeking romantic getaways, offering stunning scenery and family-friendly experiences. Visitors can explore beautiful lakes, vibrant fairgrounds, and state parks that showcase the region's natural beauty. With a variety of attractions to enjoy, Southern Illinois promises memorable adventures for everyone.

  • Rend Lake: Located 13 miles from Southern Illinois, Rend Lake offers a picturesque setting perfect for outdoor enthusiasts. Enjoy romantic beach vibes, stunning scenery, and a range of activities such as fishing, boating, and picnicking along the shore.
  • Jefferson County Fairgrounds: Just 3 miles away, the Jefferson County Fairgrounds is a lively destination for families. Experience local events, fairs, and community gatherings in a welcoming outdoor environment that fosters fun and togetherness.
  • Wayne Fitzgerrell State Park: Situated 14 miles from Southern Illinois, this national park is an adventurer's paradise. Discover breathtaking views, hiking trails, and various outdoor activities that highlight the natural beauty of the region.

Best time to go to Southern Illinois

The best time to visit Southern Illinois is dependent on what kind of holiday you are seeking. July is its hottest month on average. At this time, visitor numbers are slightly high and weather is mostly sunny with light rain. January is its coolest month on average. At this time, visitor numbers are slightly low and weather is mostly cloudy with light rain.

calendarCalendar MonthtemperatureTemperaturerainPrecipitationmostlyCloudinessoccupationOccupancypricePricing
January30.9°F (-0.6°C)Light RainMostly CloudySlightly LowSlightly Low
February36.9°F (2.7°C)Light RainMostly CloudySlightly LowSlightly Low
March48.0°F (8.9°C)Light RainMostly SunnyAverageAverage
April55.2°F (12.9°C)Light RainMostly SunnySlightly LowSlightly High
May66.7°F (19.3°C)Light RainMostly SunnyAverageAverage
June75.9°F (24.4°C)Light RainMostly SunnySlightly HighSlightly High
July78.8°F (26.0°C)Light RainMostly SunnySlightly HighSlightly High
August77.0°F (25.0°C)Light RainMostly SunnySlightly HighAverage
September71.2°F (21.8°C)Light RainMostly SunnyAverageAverage
October56.7°F (13.7°C)Light RainMostly SunnyAverageAverage
November46.6°F (8.1°C)Light RainMostly SunnyAverageSlightly Low
December39.0°F (3.9°C)Light RainMostly SunnyAverageAverage

The nearest major airports for your trip to Southern Illinois

When visiting Southern Illinois, you can fly into several major airports. St. Louis Lambert International Airport (STL) is 88 miles away, with nearby hotels such as The Ritz-Carlton, St. Louis and Ameristar Casino Resort and Spa, both 7 miles from the airport. Evansville Regional Airport (EVV) is 74 miles away, offering hotel options like DoubleTree by Hilton Evansville, 6 miles from the airport, and Holiday Inn Evansville Airport, just 0.8 miles away. Bloomington-Normal Central Illinois Regional Airport (BMI) is 152 miles from Southern Illinois, with hotels like DoubleTree by Hilton Hotel Bloomington, 3 miles away, and Hyatt Place Bloomington/Normal, 4 miles away.

Explore a world of travel with Expedia