A forested valley with autumn foliage, a rocky cliff, and a sunset.

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Our top choices for Southern Illinois hotels

Spa
Hot tub
Adults only
Bed & breakfast
Breakfast included

1. Comfort Suites Mount Vernon

Comfort Suites Mount Vernon
Mount Vernon
United States
Erica
$122 nightly
$138 total
Aug 30 - Aug 31
Total with taxes and fees
Comfort Suites Mount Vernon

2. Holiday Inn Express & Suites Mount Vernon by IHG

Holiday Inn Express & Suites Mount Vernon by IHG
Mount Vernon
United States
Angela D
$114 nightly
$129 total
Aug 30 - Aug 31
Total with taxes and fees
Holiday Inn Express & Suites Mount Vernon by IHG

3. DoubleTree by Hilton Mt. Vernon

DoubleTree by Hilton Mt. Vernon
Mount Vernon
United States
Samuel
$137 nightly
$154 total
Aug 27 - Aug 28
Total with taxes and fees
DoubleTree by Hilton Mt. Vernon

4. Super 8 by Wyndham Mt. Vernon IL

Super 8 by Wyndham Mt. Vernon IL
Mount Vernon
United States
Matthew W,
$70 nightly
$80 total
Aug 30 - Aug 31
Total with taxes and fees
Super 8 by Wyndham Mt. Vernon IL

5. Days Inn by Wyndham Mount Vernon

Days Inn by Wyndham Mount Vernon
Mount Vernon
United States
Norberto
$71 nightly
$81 total
Sep 7 - Sep 8
Total with taxes and fees
Days Inn by Wyndham Mount Vernon

6. Quality Inn Mount Vernon, IL

Quality Inn Mount Vernon, IL
Mount Vernon
United States
Kristin
$76 nightly
$86 total
Aug 30 - Aug 31
Total with taxes and fees
Quality Inn Mount Vernon, IL

7. Fairfield Inn & Suites by Marriott Mt. Vernon Rend Lake

Fairfield Inn & Suites by Marriott Mt. Vernon Rend Lake
Mount Vernon
United States
Blake
$105 nightly
$118 total
Sep 17 - Sep 18
Total with taxes and fees
Fairfield Inn & Suites by Marriott Mt. Vernon Rend Lake

8. Motel 6 Mount Vernon, IL

Motel 6 Mount Vernon, IL
Mount Vernon
United States
Emil
Motel 6 Mount Vernon, IL

9. SureStay Hotel by Best Western Whittington Rend Lake

SureStay Hotel by Best Western Whittington Rend Lake
Whittington
United States
Vinay
$81 nightly
$90 total
Sep 6 - Sep 7
Total with taxes and fees
SureStay Hotel by Best Western Whittington Rend Lake

10. Royal Inn

Royal Inn
Mount Vernon
United States
Dorisa
$63 nightly
$72 total
Aug 25 - Aug 26
Total with taxes and fees
Royal Inn

11. Americas Best Value Inn Mount Vernon

Americas Best Value Inn Mount Vernon
Mount Vernon
United States
Jim
$72 nightly
$82 total
Aug 25 - Aug 26
Total with taxes and fees
Americas Best Value Inn Mount Vernon

12. Best Western Plus Centralia Hotel & Suites

Best Western Plus Centralia Hotel & Suites
Centralia
United States
Corey
$149 nightly
$167 total
Aug 25 - Aug 26
Total with taxes and fees
Best Western Plus Centralia Hotel & Suites

13. Holiday Inn Express & Suites Salem by IHG

Holiday Inn Express & Suites Salem by IHG
Salem
United States
Todd
$110 nightly
$123 total
Sep 20 - Sep 21
Total with taxes and fees
Holiday Inn Express & Suites Salem by IHG

14. Country Garden & Suites

Country Garden & Suites
Benton
United States
Lazarina
$69 nightly
$76 total
Aug 31 - Sep 1
Total with taxes and fees
Country Garden & Suites

15. Americas Best Value Inn West Frankfort

Americas Best Value Inn West Frankfort
West Frankfort
United States
Byron
$72 nightly
$80 total
Aug 28 - Aug 29
Total with taxes and fees
Americas Best Value Inn West Frankfort

16. Fairgrounds Inn

Fairgrounds Inn
Du Quoin
United States
Mark
$79 nightly
$88 total
Aug 30 - Aug 31
Total with taxes and fees
Fairgrounds Inn

17. Days Inn by Wyndham Salem, Illinois

Days Inn by Wyndham Salem, Illinois
Salem
United States
Lucas
$48 nightly
$53 total
Sep 20 - Sep 21
Total with taxes and fees
Days Inn by Wyndham Salem, Illinois

18. Quality Inn & Suites Salem near I-57

Quality Inn & Suites Salem near I-57
Salem
United States
Tammy
$64 nightly
$70 total
Sep 13 - Sep 14
Total with taxes and fees
Quality Inn & Suites Salem near I-57

19. Super 8 by Wyndham Du Quoin

Super 8 by Wyndham Du Quoin
Du Quoin
United States
Wendy
$84 nightly
$93 total
Sep 18 - Sep 19
Total with taxes and fees
Super 8 by Wyndham Du Quoin

20. centralia motel

centralia motel
Centralia
United States
Charity
$72 nightly
$80 total
Aug 26 - Aug 27
Total with taxes and fees
centralia motel
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Vacation Rentals in Southern Illinois

Cottage

Country Home Near EIU & Lake Charleston!

Country Home Near EIU & Lake Charleston!
Charleston
"Property was very clean and beautifully decorated in a farmhouse style. Very cozy and comfortable! Came stocked with everything you would need. We had fun at nearby Aikman Wildlife Adventure in Arcola, Kayaking in Lake Charleston, hiking in Fox Ridge State Park a visit to Amish country in Arthur, IL. The kitchen, living and dining room were very spacious! The bathroom was very tiny so if staying with 4 adults - be prepared for this. Also there was a strange odor right outside the front entry...
Country Home Near EIU & Lake Charleston!
Cottage

Peaceful Robinson Home w/ Yard, Near Golf Courses!

Peaceful Robinson Home w/ Yard, Near Golf Courses!
Robinson
Peaceful Robinson Home w/ Yard, Near Golf Courses!
Apartment

Murphysboro Retreat w/ Deck Near Kinkaid Lake!

Murphysboro Retreat w/ Deck Near Kinkaid Lake!
Murphysboro
"This is a very clean and nice apartment within a very close drive to the Kinkaid boat launch. Easy to locate and can fit a car with a boat in tow no problem. This spot was also much more quiet than the campground or RV spots nearby. They have a great porch and a grill and we didn’t bring something for it which made me sad. "
Murphysboro Retreat w/ Deck Near Kinkaid Lake!
Cottage

Harrisburg Home w/ Private Yard + Screened Porch!

Harrisburg Home w/ Private Yard + Screened Porch!
Harrisburg
"We love how accommodating, helpful and responsive Hollie and Clayton were. The rental had everything we needed and then some. Very clean, cozy and comfortable. We chose this location, because it was close to the different parks and trails we had visited. Thank you, Hollie and Clayton, for being such gracious hosts."
Harrisburg Home w/ Private Yard + Screened Porch!
Cottage

Illinois Vacation Rental Home: Pets Welcome

Illinois Vacation Rental Home: Pets Welcome
Palestine
Illinois Vacation Rental Home: Pets Welcome
Cottage

Cozy Anna Home Near Southern Illinois Attractions!

Cozy Anna Home Near Southern Illinois Attractions!
Anna
"Good communication with the owners. Nice perks such as coffee, tea, and hygiene items."
Cozy Anna Home Near Southern Illinois Attractions!
Cottage

Mins to Local Attractions: Pet Friendly w/ Yard!

Mins to Local Attractions: Pet Friendly w/ Yard!
Casey
"Property was very clean and quiet, will definitely schedule for next family reunion."
Mins to Local Attractions: Pet Friendly w/ Yard!
Cottage

Beautiful Makanda Cabin in Shawnee National Forest

Beautiful Makanda Cabin in Shawnee National Forest
Makanda
"It was very peaceful and relaxing. "
Beautiful Makanda Cabin in Shawnee National Forest
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Stay near popular Southern Illinois attractions

A rocky landscape with a sunset in the background.

Garden of the Gods Recreation Area

9.8/10 (63 reviews)
See for yourself why Harrisburg’s unearthly sandstone formations, tucked within lush Shawnee National Forest, earn their ethereal name.
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A rock formation with a tree growing in the center.
Photo by Southernmost Illinois Tourism Bureau

Giant City State Park

9.2/10 (141 reviews)
Walk amid mystical woodland, admire geological wonders, go horseback riding and camp in the wilderness in the spectacular countryside of Southwest Illinois.
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O'Fallon Family Sports Park

8.6/10 (137 reviews)
This sports complex features premium turf fields, splash pads, and fishing ponds in a family-friendly setting. Watch tournaments or enjoy the scenic walking trail that winds around natural areas.
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World Wide Technology Raceway

9.0/10 (2 reviews)
Catch an event at World Wide Technology Raceway during your trip to St. Louis. Attend a sporting event or simply enjoy the top-notch restaurants while you're in the area.
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Harrah's Metropolis

8.0/10 (310 reviews)
This riverside casino offers over 600 slot machines and 17 table games along the scenic Ohio River. Join the rewards program to maximize your experience while enjoying Southern classics at the on-site restaurants.
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Learn more about Southern Illinois

Discover the culture and history of this region shaped by indigenous and pioneering communities and spend time in its peaceful, picturesque landscapes.

See all hotels in Southern Illinois
A forested valley with autumn foliage, a rocky cliff, and a sunset.
Photo by Southernmost Illinois Tourism Bureau

Top Southern Illinois Hotel Reviews

Baymont by Wyndham Effingham

Baymont by Wyndham Effingham

10/10 Excellent
"Front desk lady was so nice! Personable. Helpful. Clean nice room! Quiet stay. Would definitely stay again."
Lina 1-night trip
Posted 2 hours ago
Baymont by Wyndham Effingham
Quality Inn O'Fallon - St. Louis - Shiloh

Quality Inn O'Fallon - St. Louis - Shiloh

10/10 Excellent
"Great value- Clean room - Amazing staff- Surprisingly good breakfast - Plenty of surrounding food options"
Ollie 2-night trip
Posted 7 hours ago
Quality Inn O'Fallon - St. Louis - Shiloh
Comfort Inn Edwardsville - St. Louis

Comfort Inn Edwardsville - St. Louis

8/10 Good
"Nice one night stay for me and my toddler."
Shakia 1-night trip
Posted 10 hours ago
Comfort Inn Edwardsville - St. Louis
Best Western St. Louis Fairview Heights

Best Western St. Louis Fairview Heights

10/10 Excellent
"Everything was good.and clean"
Garry 1-night trip
Posted 1 day ago
Best Western St. Louis Fairview Heights
Country Inn & Suites by Radisson, Effingham, IL

Country Inn & Suites by Radisson, Effingham, IL

8/10 Good
"Someone was smoking weed. We could smell it when we came back in the evening from supper. Not on our floor, but the elevator stunk. The carpet felt damp,"
Kristen 1-night trip
Posted 2 days ago
Country Inn & Suites by Radisson, Effingham, IL
Motel 6 Caseyville, IL - Caseyville Il

Motel 6 Caseyville, IL - Caseyville Il

10/10 Excellent
"Great place to stay it was clean and staff was helpful!"
Brittany 2-night trip
Posted 2 days ago
Motel 6 Caseyville, IL - Caseyville Il
Drury Inn & Suites St. Louis Fairview Heights

Drury Inn & Suites St. Louis Fairview Heights

10/10 Excellent
"Easy parking, dinner and breakfast great"
Fiona 1-night trip
Posted 2 days ago
Drury Inn & Suites St. Louis Fairview Heights
Country Inn & Suites by Radisson, Fairview Heights, IL

Country Inn & Suites by Radisson, Fairview Heights, IL

10/10 Excellent
"Me and my sister had a good time. We enjoyed our stay. We ready to go back again and just got home."
Denise 4-night trip
Posted 2 days ago
Country Inn & Suites by Radisson, Fairview Heights, IL
Holiday Inn Express Metropolis by IHG

Holiday Inn Express Metropolis by IHG

10/10 Excellent
"Very friendly"
Valerie 2-night trip
Posted 2 days ago
Holiday Inn Express Metropolis by IHG

More cheap stays in Southern Illinois

Super 8 by Wyndham O'Fallon

Super 8 by Wyndham O'Fallon

1100 Eastgate Dr O'Fallon IL
$54 nightly
$63 total
Aug 31 - Sep 1
Total with taxes and fees
Super 8 by Wyndham O'Fallon
Baymont by Wyndham Effingham

Baymont by Wyndham Effingham

1811 W Fayette Avenue Effingham IL
$72 nightly
$80 total
Aug 30 - Aug 31
Total with taxes and fees
8.2/10 Very Good! (1,011 reviews)
Baymont by Wyndham Effingham
Best Western St. Louis Fairview Heights

Best Western St. Louis Fairview Heights

150 Ludwig Dr Fairview Heights IL
$80 nightly
$90 total
Aug 30 - Aug 31
Total with taxes and fees
7.4/10 Good! (97 reviews)
Best Western St. Louis Fairview Heights
Baymont by Wyndham Marion

Baymont by Wyndham Marion

2608 W Main St Marion IL
$81 nightly
$97 total
Sep 1 - Sep 2
Total with taxes and fees
8.4/10 Very Good! (1,097 reviews)
Baymont by Wyndham Marion
Holiday Inn Express Metropolis by IHG

Holiday Inn Express Metropolis by IHG

2179 East 5th Street Metropolis IL
$102 nightly
$113 total
Sep 21 - Sep 22
Total with taxes and fees
8.8/10 Excellent! (1,018 reviews)
Holiday Inn Express Metropolis by IHG
Comfort Suites Mount Vernon

Comfort Suites Mount Vernon

404 South 44th Street Mount Vernon IL
$122 nightly
$138 total
Aug 30 - Aug 31
Total with taxes and fees
Comfort Suites Mount Vernon

Hotels in Southern Illinois with star-rating

Find out more about Southern Illinois

These Southern Illinois insights are based on real traveler data from Expedia, aggregated using AI to help you plan your trip. Updated: .

Top reasons to visit Southern Illinois

  • Stunning Natural Scenery: Southern Illinois boasts breathtaking landscapes, including the scenic Shawnee Hills and beautiful lakes.
  • Outdoor Adventures: The region offers a variety of outdoor activities, from hiking and camping to fishing and boating.
  • Charming Accommodations: Enjoy a range of lodging options, from luxurious hotels to cozy cabins, catering to all travelers.
  • Family-Friendly Attractions: Explore vibrant fairgrounds and state parks that provide fun for visitors of all ages.
  • Romantic Getaways: Southern Illinois is perfect for couples seeking a peaceful retreat amidst nature's beauty.

Find great hotels near Southern Illinois

Experience the charm of Southern Illinois with a range of hotel accommodations tailored to your needs. From luxurious lodgings to family-friendly motels, you'll find pet-friendly options and quality inns perfect for business travelers and vacationers alike. Explore Carbondale hotels and select luxury hotels that cater to every type of guest, ensuring a comfortable and enjoyable stay in this beautiful region.

  • Drury Plaza Hotel Mt. Vernon: Drury Plaza Hotel Mt. Vernon is a highly-rated 3-star hotel, boasting a remarkable guest rating of 9.6. Situated 6 miles from Southern Illinois, this property is an excellent choice for families, business travelers, and pet owners. Guests appreciate the family-friendly amenities, including free cribs and pet allowances, making it a welcoming environment for all. The hotel features a complimentary breakfast, an indoor pool, and a fitness center, ensuring a comfortable and enjoyable stay. The combination of modern facilities and a warm atmosphere makes Drury Plaza Hotel a top pick for travelers seeking both convenience and comfort.
  • Comfort Suites Mount Vernon: Comfort Suites Mount Vernon is a budget-friendly option with a solid guest rating of 9.0, located 5 miles from Southern Illinois. This hotel is perfect for families, business travelers, and pet lovers alike. Offering amenities like free cribs and window guards for children, it ensures a safe and accommodating stay for families. Guests can enjoy spacious suites and a complimentary breakfast, as well as pet-friendly policies that allow for a hassle-free experience. Comfort Suites stands out for its blend of affordability and practicality, making it a smart choice for budget-conscious travelers.
  • Super 8 by Wyndham Mt. Vernon IL: Super 8 by Wyndham Mt. Vernon IL is a budget-friendly hotel known for its welcoming atmosphere, rated 9.0 by guests. Located 6 miles from Southern Illinois, it caters to families, business travelers, and pet owners. The hotel provides essential amenities such as free cribs, window guards for children, and a first aid kit, ensuring peace of mind for families. With pet-friendly policies and affordable rates, Super 8 offers a convenient stay without compromising on comfort, making it an ideal choice for travelers looking for value.

Where to stay near Southern Illinois

Southern Illinois is a hidden gem for travelers seeking outdoor adventures and romantic getaways. With its scenic Shawnee Hills and charming lakeside cabins, it offers a perfect blend of relaxation and recreation. Explore family-friendly towns and enjoy the friendly atmosphere while discovering the rural beauty of the region. Just a short drive from St. Louis, Southern Illinois promises an unforgettable experience filled with stunning landscapes and welcoming communities.

  • Mount Vernon: Nestled a mere 4 miles from Southern Illinois, Mount Vernon is an inviting city perfect for outdoor enthusiasts and those seeking scenic beauty. With a steady flow of visitors year-round, the peak season arrives in April and from June to July. Travelers flock to Mount Vernon for its romantic atmosphere and access to recreational areas, educational venues, and campgrounds. Nearby attractions include picturesque lakes, lush forests, and the stunning national state park, making it an ideal destination for a nature-filled getaway.
  • Opdyke: Also located 4 miles from Southern Illinois, Opdyke is a charming city with a welcoming vibe. Visitor numbers remain relatively stable throughout the year, with peaks in January to February and August. Known for its outdoor experiences and romantic settings, Opdyke offers a tranquil escape. The city is home to educational institutions and is surrounded by beautiful lakes and a modern college university, providing ample opportunities for exploration and relaxation.
  • Bonnie: Situated 6 miles from Southern Illinois, Bonnie is a delightful city that attracts seasonal visitors, especially in May and from July to August. Known for its outdoor adventures and scenic landscapes, Bonnie offers a romantic getaway for couples and families alike. Visitors can enjoy recreational areas, fairgrounds, and trail access, while local landmarks such as beautiful lakes, a national state park, and a visitor center enhance the experience. Bonnie's charm lies in its blend of nature and community activities, making it a great stop on your Southern Illinois journey.

Things to do in Southern Illinois

Southern Illinois is a perfect destination for outdoor enthusiasts and couples seeking a romantic getaway. With its stunning scenery, visitors can enjoy a variety of activities including recreational areas and campgrounds. It's also an ideal location for hosting weddings and parties, making it a versatile choice for both adventure and celebration. Experience the natural beauty and charm that Southern Illinois has to offer.

Shopping

In Southern Illinois, explore the bustling Carbondale Mall for a variety of stores, or visit the charming shops at the historic Murphysboro Market for unique gifts. Don’t miss the local artisan goods at the Shawnee Hills Wine Trail, perfect for memorable souvenirs.

Recreation

Experience tranquility at the New Life Wellness Spa, where you can indulge in rejuvenating massages and holistic therapies. Explore the nearby Shawnee National Forest for hiking, birdwatching, and connecting with nature, offering a perfect blend of relaxation and outdoor adventure.

Adventure

In Southern Illinois, explore the breathtaking Giant City State Park with its hiking trails and rock formations. Experience the thrill of zip-lining at Shawnee Bluffs Canopy Tour, or embark on a kayaking adventure on the beautiful Cache River, immersing yourself in the area's rich natural beauty.

Nightlife

Explore the vibrant nightlife at The Varsity Center in Carbondale, where you can catch live performances and events. For a laid-back vibe, visit The Cellar, a cozy spot for craft beers and cocktails. Don't miss the lively atmosphere at Pinch Penny Pub, known for its fun games and friendly crowd.

*Distances are measured in a straight line; actual driving distances may vary depending on the route.

Booking tips and Expedia advantages for Southern Illinois

  • The most and least expensive months on average to stay in a hotel: The cheapest months to stay around Southern Illinois are January to February and November, where the prices are slightly lower. This is in comparison to April and June to July, where prices are slightly higher.
  • The most and least expensive days on average to stay in a hotel: The least expensive day to stay around Southern Illinois is Tuesday. The most expensive day to stay around Southern Illinois is Saturday.
  • Find cheap hotels on Expedia: Utilize Expedia's search tool to refine your options based on your budget, desired location, and preferred hotel type. To find the best prices and deals, simply arrange the price filter from lowest to highest.
  • Consider bundling your trip: You can save money by combining your hotel stay in Southern Illinois with your flights and activities through an Expedia package deal.

Find the best attractions near Southern Illinois

Southern Illinois is perfect for outdoor enthusiasts and those seeking romantic getaways, offering stunning scenery and family-friendly experiences. Visitors can explore beautiful lakes, vibrant fairgrounds, and state parks that showcase the region's natural beauty. With a variety of attractions to enjoy, Southern Illinois promises memorable adventures for everyone.

  • Rend Lake: Located 13 miles from Southern Illinois, Rend Lake offers a picturesque setting perfect for outdoor enthusiasts. Enjoy romantic beach vibes, stunning scenery, and a range of activities such as fishing, boating, and picnicking along the shore.
  • Jefferson County Fairgrounds: Just 3 miles away, the Jefferson County Fairgrounds is a lively destination for families. Experience local events, fairs, and community gatherings in a welcoming outdoor environment that fosters fun and togetherness.
  • Wayne Fitzgerrell State Park: Situated 14 miles from Southern Illinois, this national park is an adventurer's paradise. Discover breathtaking views, hiking trails, and various outdoor activities that highlight the natural beauty of the region.

Best time to go to Southern Illinois

The best time to visit Southern Illinois is dependent on what kind of holiday you are seeking. July is its hottest month on average. At this time, visitor numbers are slightly high and weather is mostly sunny with light rain. January is its coolest month on average. At this time, visitor numbers are slightly low and weather is mostly cloudy with light rain.

calendarCalendar MonthtemperatureTemperaturerainPrecipitationmostlyCloudinessoccupationOccupancypricePricing
January30.9°F (-0.6°C)Light RainMostly CloudySlightly LowSlightly Low
February36.9°F (2.7°C)Light RainMostly CloudySlightly LowSlightly Low
March48.0°F (8.9°C)Light RainMostly SunnyAverageAverage
April55.2°F (12.9°C)Light RainMostly SunnySlightly LowSlightly High
May66.7°F (19.3°C)Light RainMostly SunnyAverageAverage
June75.9°F (24.4°C)Light RainMostly SunnySlightly HighSlightly High
July78.8°F (26.0°C)Light RainMostly SunnySlightly HighSlightly High
August77.0°F (25.0°C)Light RainMostly SunnySlightly HighAverage
September71.2°F (21.8°C)Light RainMostly SunnyAverageAverage
October56.7°F (13.7°C)Light RainMostly SunnyAverageAverage
November46.6°F (8.1°C)Light RainMostly SunnyAverageSlightly Low
December39.0°F (3.9°C)Light RainMostly SunnyAverageAverage

The nearest major airports for your trip to Southern Illinois

When visiting Southern Illinois, you can fly into several major airports. St. Louis Lambert International Airport (STL) is 88 miles away, with nearby hotels such as The Ritz-Carlton, St. Louis and Ameristar Casino Resort and Spa, both 7 miles from the airport. Evansville Regional Airport (EVV) is 74 miles away, offering hotel options like DoubleTree by Hilton Evansville, 6 miles from the airport, and Holiday Inn Evansville Airport, just 0.8 miles away. Bloomington-Normal Central Illinois Regional Airport (BMI) is 152 miles from Southern Illinois, with hotels like DoubleTree by Hilton Hotel Bloomington, 3 miles away, and Hyatt Place Bloomington/Normal, 4 miles away.

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