Title: Southern Illinois Vacation Rentals from $112: Search Short-Term Rentals | Expedia.com

[Southern Illinois Travel Guide](https://expedia.com/Southern-Illinois.dx6233859)[Hotels in Southern Illinois](https://expedia.com/Southern-Illinois-Hotels.d6233859.Travel-Guide-Hotels)[Flights to Southern Illinois](https://expedia.com/Cheap-Flights-To-Southern-Illinois.d6233859.Travel-Guide-Flights)[Car Rentals in Southern Illinois](https://expedia.com/Car-Rentals-In-Southern-Illinois.d6233859.Car-Rental-Guide)[Southern Illinois Vacation Packages](https://expedia.com/Southern-Illinois.d6233859.Destination-Travel-Guides)

![Southern Illinois showing forest scenes, a sunset and landscape views](https://images.trvl-media.com/place/553248635944113522/0e29d2f8-2d58-457a-908d-4b89b13776d9.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

Photo by Southernmost Illinois Tourism Bureau

![](https://images.trvl-media.com/place/553248635944113522/0e29d2f8-2d58-457a-908d-4b89b13776d9.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

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## Check prices for these dates

In two weeks

[Mar 27 - Mar 29](https://www.expedia.com/Hotel-Search?regionId=6233859&startDate=2026-03-27&endDate=2026-03-29&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In two months

[May 8 - May 10](https://www.expedia.com/Hotel-Search?regionId=6233859&startDate=2026-05-08&endDate=2026-05-10&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In three months

[Jun 5 - Jun 7](https://www.expedia.com/Hotel-Search?regionId=6233859&startDate=2026-06-05&endDate=2026-06-07&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In four months

[Jul 3 - Jul 5](https://www.expedia.com/Hotel-Search?regionId=6233859&startDate=2026-07-03&endDate=2026-07-05&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

## Our top choices for Southern Illinois vacation rentals

![House (2 Bedrooms) | Front of property](https://images.trvl-media.com/lodging/120000000/119740000/119734200/119734109/57d00814.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![House (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/120000000/119740000/119734200/119734109/b80c1dc0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![House (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/120000000/119740000/119734200/119734109/b359a748.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![House (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/120000000/119740000/119734200/119734109/b236e0dc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Cottage in Granite City

[](https://www.expedia.com/Lakefront-Family-Home-13-Mi-From-Gateway-Arch.h119734109.Hotel-Information)

$364 nightly

$401 total

Mar 11 - Mar 12

Total with taxes and fees

[](https://www.expedia.com/Lakefront-Family-Home-13-Mi-From-Gateway-Arch.h119734109.Hotel-Information)

![House (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/120000000/119740000/119734200/119734107/c7904d3a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![House (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/120000000/119740000/119734200/119734107/28c20fa0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![House (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/120000000/119740000/119734200/119734107/98ac6197.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![House (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/120000000/119740000/119734200/119734107/870bf7d2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Cottage in Granite City

[](https://www.expedia.com/St-Louis-Hotels-12-Mi-To-St-Louis-Pet-Friendly-Metro-East-Home.h119734107.Hotel-Information)

$186 nightly

$205 total

Mar 11 - Mar 12

Total with taxes and fees

[](https://www.expedia.com/St-Louis-Hotels-12-Mi-To-St-Louis-Pet-Friendly-Metro-East-Home.h119734107.Hotel-Information)

![House (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/114000000/113670000/113662500/113662484/7a5972ac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![House (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/114000000/113670000/113662500/113662484/c0f74c35.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![House (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/114000000/113670000/113662500/113662484/cbac1345.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![House (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/114000000/113670000/113662500/113662484/ac938d2c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Cottage in Casey

[](https://www.expedia.com/Casey-Hotels-Pet-Friendly-Home-W-Fenced-Yard-Cozy-In-Casey.h113662484.Hotel-Information)

10/10

Exceptional

(1 review)

"Property was very clean and quiet, will definitely schedule for next family reunion."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Anthony

$217 nightly

$238 total

Mar 11 - Mar 12

Total with taxes and fees

[](https://www.expedia.com/Casey-Hotels-Pet-Friendly-Home-W-Fenced-Yard-Cozy-In-Casey.h113662484.Hotel-Information)

![House (1 Bedroom) | Front of property](https://images.trvl-media.com/lodging/124000000/123670000/123661900/123661842/aa6e717a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![House (1 Bedroom) | Interior](https://images.trvl-media.com/lodging/124000000/123670000/123661900/123661842/d5f4e688.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![House (1 Bedroom) | Interior](https://images.trvl-media.com/lodging/124000000/123670000/123661900/123661842/3ed90f05.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![House (1 Bedroom) | Interior](https://images.trvl-media.com/lodging/124000000/123670000/123661900/123661842/02464d31.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Cottage in Murphysboro

[](https://www.expedia.com/Murphysboro-Hotels-Lakefront.h123661842.Hotel-Information)

$217 nightly

$238 total

Mar 11 - Mar 12

Total with taxes and fees

[](https://www.expedia.com/Murphysboro-Hotels-Lakefront.h123661842.Hotel-Information)

![View from property](https://images.trvl-media.com/lodging/111000000/110560000/110550900/110550817/d4a93b47.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, desk, laptop workspace, bed sheets](https://images.trvl-media.com/lodging/111000000/110560000/110550900/110550817/72fc0b4a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, desk, laptop workspace, bed sheets](https://images.trvl-media.com/lodging/111000000/110560000/110550900/110550817/b6c1f98e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![View from property](https://images.trvl-media.com/lodging/111000000/110560000/110550900/110550817/ebca14b0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Cabin in French Village

[](https://www.expedia.com/French-Village-Hotels-Postcard-Cabins-St-Francois.h110550817.Hotel-Information)

9.8/10

Exceptional

(56 reviews)

"I had a great time with my mom there!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Lily

$134 nightly

$144 total

Mar 16 - Mar 17

Total with taxes and fees

[](https://www.expedia.com/French-Village-Hotels-Postcard-Cabins-St-Francois.h110550817.Hotel-Information)

![Interior](https://images.trvl-media.com/lodging/127000000/126620000/126617400/126617355/804f0425.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior detail](https://images.trvl-media.com/lodging/127000000/126620000/126617400/126617355/2cb1c224.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/127000000/126620000/126617400/126617355/9e44784b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Suite, 1 Queen Bed with Sofa bed, Pets Allowed | Interior](https://images.trvl-media.com/lodging/127000000/126620000/126617400/126617355/d395df9b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Aparthotel in Perryville

[](https://www.expedia.com/Perryville-Hotels-The-Atrium-A-Boutique-Hotel.h126617355.Hotel-Information)

$137 nightly

$158 total

Mar 11 - Mar 12

Total with taxes and fees

[](https://www.expedia.com/Perryville-Hotels-The-Atrium-A-Boutique-Hotel.h126617355.Hotel-Information)

![Terrace/patio](https://images.trvl-media.com/lodging/84000000/83520000/83516600/83516509/8557dc4b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![House | Living area](https://images.trvl-media.com/lodging/84000000/83520000/83516600/83516509/972e20f8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![House | 1 bedroom](https://images.trvl-media.com/lodging/84000000/83520000/83516600/83516509/e3c698b1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![House | Living area](https://images.trvl-media.com/lodging/84000000/83520000/83516600/83516509/14339969.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Vacation Home in French Village

[](https://www.expedia.com/French-Village-Hotels-Tiny-Houses-Of-French-Village.h83516509.Hotel-Information)

10/10

Exceptional

(3 reviews)

"Charming property with a space for everything and everything in its place. Would not hesitate to recommend or stay again."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Norma

$325 nightly

$346 total

Mar 11 - Mar 12

Total with taxes and fees

[](https://www.expedia.com/French-Village-Hotels-Tiny-Houses-Of-French-Village.h83516509.Hotel-Information)

![House (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/123000000/122900000/122892200/122892138/9b8cfc2e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![House (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/123000000/122900000/122892200/122892138/2ea775b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![House (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/123000000/122900000/122892200/122892138/7ebce143.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![House (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/123000000/122900000/122892200/122892138/a51b6a8b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Cottage in Cunningham

[](https://www.expedia.com/Quiet-Country-Stay-Modern-Home-Near-Paducah.h122892138.Hotel-Information)

$271 nightly

$290 total

Mar 11 - Mar 12

Total with taxes and fees

[](https://www.expedia.com/Quiet-Country-Stay-Modern-Home-Near-Paducah.h122892138.Hotel-Information)

![Interior](https://images.trvl-media.com/lodging/127000000/126480000/126472100/126472041/78552352.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/127000000/126480000/126472100/126472041/823bb914.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/127000000/126480000/126472100/126472041/c717ca95.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/127000000/126480000/126472100/126472041/24e9047d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Cottage in The Gate

[](https://www.expedia.com/St-Louis-Hotels-3323-Uptown-Elegant-Escape-By-JZ-Vacation-Rentals.h126472041.Hotel-Information)

$738 nightly

$863 total

Mar 15 - Mar 16

Total with taxes and fees

[](https://www.expedia.com/St-Louis-Hotels-3323-Uptown-Elegant-Escape-By-JZ-Vacation-Rentals.h126472041.Hotel-Information)

![Studio Suite, 1 King Bed | Desk, laptop workspace, blackout drapes, WiFi](https://images.trvl-media.com/lodging/1000000/20000/20000/19976/7caaaee1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Combined shower/tub, towels, soap, shampoo](https://images.trvl-media.com/lodging/1000000/20000/20000/19976/w2885h1876x11y0-1194952e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Full-size fridge, microwave, stovetop, dishwasher](https://images.trvl-media.com/lodging/1000000/20000/20000/19976/ca0bafbf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Combined shower/tub, towels, soap, shampoo](https://images.trvl-media.com/lodging/1000000/20000/20000/19976/af9b69ed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Aparthotel in Maryland Heights

[](https://www.expedia.com/St-Louis-Hotels-Craigshire-Suites.h19976.Hotel-Information)

7.0/10

Good

(1,110 reviews)

"We’ve stayed here twice before and have always been pleased with everything. Very good hotel close to what we need."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Timothy

$475 nightly

$551 total

Mar 11 - Mar 12

Total with taxes and fees

[](https://www.expedia.com/St-Louis-Hotels-Craigshire-Suites.h19976.Hotel-Information)

![Family House, Garden View | Private kitchen](https://images.trvl-media.com/lodging/127000000/126290000/126290000/126289991/2ab0ba1a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/127000000/126290000/126290000/126289991/8bfe9456.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Family House, Garden View | Dining](https://images.trvl-media.com/lodging/127000000/126290000/126290000/126289991/ce415ad9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Family House, Garden View | Iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/127000000/126290000/126290000/126289991/c9f1b55e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Vacation Home in Bevo Mill

[](https://www.expedia.com/St-Louis-Hotels-Spacious-3BR-House-In-St-Louis.h126289991.Hotel-Information)

$654 nightly

$765 total

Mar 15 - Mar 16

Total with taxes and fees

[](https://www.expedia.com/St-Louis-Hotels-Spacious-3BR-House-In-St-Louis.h126289991.Hotel-Information)

![Full-size fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/77000000/76390000/76388000/76388000/84406cc3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Point of interest](https://images.trvl-media.com/lodging/77000000/76390000/76388000/76388000/2ec33dcf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![55-inch Smart TV with digital channels, TV, streaming services](https://images.trvl-media.com/lodging/77000000/76390000/76388000/76388000/8010cd32.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![55-inch Smart TV with digital channels, TV, streaming services](https://images.trvl-media.com/lodging/77000000/76390000/76388000/76388000/586044dd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Aparthotel in Perryville

[](https://www.expedia.com/Perryville-Hotels-Urban-Lofts.h76388000.Hotel-Information)

9.2/10

Wonderful

(17 reviews)

"Great place to stay! "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Eric

$257 nightly

$294 total

Mar 11 - Mar 12

Total with taxes and fees

[](https://www.expedia.com/Perryville-Hotels-Urban-Lofts.h76388000.Hotel-Information)

![House, Multiple Beds, Patio, City View ((#19) 3323 Vista Ave) | Private kitchen](https://images.trvl-media.com/lodging/105000000/104010000/104008500/104008447/209d3104.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![House, Multiple Beds, Patio, City View ((#19) 3323 Vista Ave) | Living area](https://images.trvl-media.com/lodging/105000000/104010000/104008500/104008447/f9583e7e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![House, Multiple Beds, Patio, City View ((#19) 3323 Vista Ave) | Interior](https://images.trvl-media.com/lodging/105000000/104010000/104008500/104008447/56a63093.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![House, Multiple Beds, Patio, City View ((#19) 3323 Vista Ave) | Living area](https://images.trvl-media.com/lodging/105000000/104010000/104008500/104008447/80ab1b36.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Vacation Home in The Gate

[](https://www.expedia.com/St-Louis-Hotels-Spacious-Family-Retreat-1-OF-2-JZ-Vacation-Rentals.h104008447.Hotel-Information)

$708 nightly

$828 total

Mar 15 - Mar 16

Total with taxes and fees

[](https://www.expedia.com/St-Louis-Hotels-Spacious-Family-Retreat-1-OF-2-JZ-Vacation-Rentals.h104008447.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/84000000/83130000/83121100/83121050/f3c125ad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Comfort Apartment | Living area | 42-inch Smart TV with digital channels, TV, Netflix](https://images.trvl-media.com/lodging/84000000/83130000/83121100/83121050/4a627d76.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![BBQ/picnic area](https://images.trvl-media.com/lodging/84000000/83130000/83121100/83121050/0bbeb61f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe Apartment | Interior entrance](https://images.trvl-media.com/lodging/84000000/83130000/83121100/83121050/55f5dbb9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Apartment in Grand Center

[](https://www.expedia.com/St-Louis-Hotels-Grand-Center-Apartments.h83121050.Hotel-Information)

8.4/10

Very Good

(129 reviews)

"Very clean and very friendly people "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Mary

$121 nightly

$135 total

Mar 24 - Mar 25

Total with taxes and fees

[](https://www.expedia.com/St-Louis-Hotels-Grand-Center-Apartments.h83121050.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

[View all properties](https://expedia.com/Hotel-Search?startDate=2026-03-24&endDate=2026-03-25&regionId=6233859&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&openPlayBack=true)

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## 

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Members save up to 40% on hotels and homes. Plan this year’s big trip and save.

[Book now](https://expedia.com/deals?rfrr=VR_SPRING_PROMO_6233859)

## Find vacation rentals that suit your style

Cabins

[](https://www.expedia.com/Hotel-Search?destination=Southern+Illinois%2C+Illinois%2C+United+States+of+America&regionId=6233859&latLong=38.412831%2C-88.824893&adults=2&startDate=2026-06-08&d1=2026-06-08&endDate=2026-06-11&d2=2026-06-11&lodging=CABIN)

Cottages

[](https://www.expedia.com/Hotel-Search?destination=Southern+Illinois%2C+Illinois%2C+United+States+of+America&regionId=6233859&latLong=38.412831%2C-88.824893&adults=2&startDate=2026-06-08&d1=2026-06-08&endDate=2026-06-11&d2=2026-06-11&lodging=COTTAGE)

Private vacation homes

[](https://www.expedia.com/Hotel-Search?destination=Southern+Illinois%2C+Illinois%2C+United+States+of+America&regionId=6233859&latLong=38.412831%2C-88.824893&adults=2&startDate=2026-06-08&d1=2026-06-08&endDate=2026-06-11&d2=2026-06-11&lodging=VACATION_HOME)

Condos

[](https://www.expedia.com/Hotel-Search?destination=Southern+Illinois%2C+Illinois%2C+United+States+of+America&regionId=6233859&latLong=38.412831%2C-88.824893&adults=2&startDate=2026-06-08&d1=2026-06-08&endDate=2026-06-11&d2=2026-06-11&lodging=CONDO)

Apartments

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Villas

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Aparthotels

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## Top Southern Illinois Hotel Reviews

![Drury Inn & Suites St. Louis Fairview Heights](https://images.trvl-media.com/lodging/1000000/50000/41900/41802/91646e6b_y.jpg)

### Drury Inn & Suites St. Louis Fairview Heights

10/10 Excellent

"Didn't visit "

[](https://expedia.com/Collinsville-Hotels-Drury-Inn-Suites-St-Louis-Fairview-Heights.h41802.Hotel-Information)

![Drury Plaza Hotel Mt. Vernon](https://images.trvl-media.com/lodging/1000000/50000/42100/42021/798d901b_y.jpg)

### Drury Plaza Hotel Mt. Vernon

2/10 Terrible

"I booked for 3/9-3/10/26\. We arrived today and were told the reservation was for last night. I’m Very clear that I selected a stay fo tonight. I have no idea how it got changed to last night. Please refund me in full for the incorrect reservation last night. "

[](https://expedia.com/Mount-Vernon-Hotels-Drury-Inn-Suites-Mt-Vernon.h42021.Hotel-Information)

![Baymont by Wyndham Effingham](https://images.trvl-media.com/lodging/1000000/10000/1600/1591/1593eb79_y.jpg)

### Baymont by Wyndham Effingham

10/10 Excellent

"Staff was extremely friendly "

[](https://expedia.com/Effingham-Hotels-Baymont-By-Wyndham-Effingham.h1591.Hotel-Information)

![Holiday Inn Express Metropolis by IHG](https://images.trvl-media.com/lodging/1000000/220000/211900/211819/667d8a92_y.jpg)

### Holiday Inn Express Metropolis by IHG

10/10 Excellent

"Nice quiet location. Room very clean. Friendly staff. Would definitely stay again if in the area. "

[](https://expedia.com/Metropolis-Hotels-Holiday-Inn-Express-Metropolis.h211819.Hotel-Information)

![Comfort Suites Mount Vernon](https://images.trvl-media.com/lodging/2000000/1390000/1387400/1387309/5b15716e_y.jpg)

### Comfort Suites Mount Vernon

4/10 Poor

"The Wi-Fi was not connecting. When I went to the front desk, the manager just gave me a phone number. The person didn't even try to take care of this. Very frustrating. I had to use my cell phone hot spot to complete my work."

[](https://expedia.com/Mount-Vernon-Hotels-Comfort-Suites-Mount-Vernon.h1387309.Hotel-Information)

![Super 8 by Wyndham Troy IL/St. Louis Area](https://images.trvl-media.com/lodging/2000000/1100000/1090700/1090603/4ee0764e_y.jpg)

### Super 8 by Wyndham Troy IL/St. Louis Area

8/10 Good

"WE were there for just an overnight so did not spend much time in the room. The room was clean. It looked like it had been repainted recently. Everything about the room and bathroom was clean. No complaints. Parking lot was well lit and the hotel was easy to get to off of I%%."

[](https://expedia.com/St-Louis-Hotels-Super-8-By-Wyndham-Troy-ILSt-Louis-Area.h1090603.Hotel-Information)

![Best Western Delta Inn](https://images.trvl-media.com/lodging/1000000/10000/3400/3382/w3840h2556x0y4-dd5ad558_y.jpg)

### Best Western Delta Inn

10/10 Excellent

" Nice location. Quiet. Good size room with two chairs. "

[](https://expedia.com/Effingham-Hotels-Best-Western-Delta-Inn.h3382.Hotel-Information)

![Drury Inn & Suites St. Louis O'Fallon, IL](https://images.trvl-media.com/lodging/2000000/1550000/1544100/1544028/2e5b0061_y.jpg)

### Drury Inn & Suites St. Louis O'Fallon, IL

10/10 Excellent

"The room was comfortable, and clean. The beds had plenty of pillows and a comfortable bed. The check in process was quick. The room had a clean bathroom and shower, with plenty of towels for us. The only issue I would bring up is that there was only 1 operational elevator which meant a delay in getting to your room not on the ground floor as many people were using the same one."

[](https://expedia.com/Collinsville-Hotels-Drury-Inn-Suites-St-Louis-OFallon.h1544028.Hotel-Information)

![Super 8 by Wyndham O'Fallon](https://images.trvl-media.com/lodging/1000000/20000/11100/11071/055d0e3b_y.jpg)

### Super 8 by Wyndham O'Fallon

2/10 Terrible

"This was the worst hotel that I had ever stayed in and NEVER again. I stayed at this hotel location years ago and it has deteriorated to the point that there are no words. My husband and I contemplated leaving, but we stayed the 2 nights out of necessity. We were in town for a funeral and needed a less expensive option for an unexpected event and I know that you get what you pay for, but Expedia needs to take this hotel option off of the list of options. It was run down, filthy, horrible ambiance and vibe and the staff didn't seem to even notice or care."

[](https://expedia.com/Collinsville-Hotels-Super-8-By-Wyndham-OFallon.h11071.Hotel-Information)

## Find out more about Southern Illinois

**Everything you need to know about Southern Illinois vacation rentals**

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Southern Illinois vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Southern Illinois vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

**Southern Illinois vacation rentals: An excellent choice for every season**

Whenever you want to travel, a warm welcome awaits you in Southern Illinois. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Southern Illinois in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $112 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

**How to find incredible deals on Southern Illinois rentals**

At Expedia, we put the best Southern Illinois vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Southern Illinois rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Southern Illinois vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Southern Illinois. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

## Explore a world of travel with Expedia

- Trending destinations on Expedia.com
- All accommodation types in Southern Illinois

### Trending destinations on Expedia.com

- [Destin Vacation Rentals ](https://www.expedia.com/Destin-Vacation-Rentals.d6906.Travel-Guide-VacationRentals)
- [Panama City Vacation Rentals ](https://www.expedia.com/Panama-City-Beach-Vacation-Rentals.d8021.Travel-Guide-VacationRentals)
- [Hilton Head Vacation Rentals ](https://www.expedia.com/Hilton-Head-Island-Vacation-Rentals.d601684.Travel-Guide-VacationRentals)
- [Gulf Shores Vacation Rentals ](https://www.expedia.com/Gulf-Shores-Vacation-Rentals.d603078.Travel-Guide-VacationRentals)
- [Key West Vacation Rentals ](https://www.expedia.com/Key-West-Vacation-Rentals.d1187.Travel-Guide-VacationRentals)
- [Gatlinburg Vacation Rentals ](https://www.expedia.com/Gatlinburg-Vacation-Rentals.d7474.Travel-Guide-VacationRentals)
- [Maui Vacation Rentals ](https://www.expedia.com/Maui-Vacation-Rentals.d180073.Travel-Guide-VacationRentals)
- [Orlando Vacation Rentals ](https://www.expedia.com/Orlando-Vacation-Rentals.d178294.Travel-Guide-VacationRentals)
- [Myrtle Beach Vacation Rentals ](https://www.expedia.com/Myrtle-Beach-Vacation-Rentals.d601685.Travel-Guide-VacationRentals)
- [Orange Beach Vacation Rentals ](https://www.expedia.com/Orange-Beach-Vacation-Rentals.d9136.Travel-Guide-VacationRentals)
- [Pigeon Forge Vacation Rentals ](https://www.expedia.com/Pigeon-Forge-Vacation-Rentals.d8264.Travel-Guide-VacationRentals)
- [Ocean City Vacation Rentals ](https://www.expedia.com/Ocean-City-Vacation-Rentals.d9151.Travel-Guide-VacationRentals)
- [Outer Banks Vacation Rentals ](https://www.expedia.com/Outer-Banks-Vacation-Rentals.d602135.Travel-Guide-VacationRentals)
- [San Diego Vacation Rentals ](https://www.expedia.com/San-Diego-Vacation-Rentals.d3073.Travel-Guide-VacationRentals)
- [Siesta Key Vacation Rentals ](https://www.expedia.com/Siesta-Key-Vacation-Rentals.d6881.Travel-Guide-VacationRentals)
- [Galveston Vacation Rentals ](https://www.expedia.com/Galveston-Vacation-Rentals.d1341.Travel-Guide-VacationRentals)
- [Clearwater Beach Vacation Rentals ](https://www.expedia.com/Clearwater-Beach-Vacation-Rentals.d10759.Travel-Guide-VacationRentals)
- [Palm Springs Vacation Rentals ](https://www.expedia.com/Palm-Springs-Vacation-Rentals.d180676.Travel-Guide-VacationRentals)
- [Florida Keys Vacation Rentals ](https://www.expedia.com/Florida-Keys-Vacation-Rentals.d6023765.Travel-Guide-VacationRentals)
- [Lake Tahoe Vacation Rentals ](https://www.expedia.com/South-Lake-Tahoe-Vacation-Rentals.d10150.Travel-Guide-VacationRentals)
- [Lake of the Ozarks Vacation Rentals ](https://www.expedia.com/Lake-Ozark-Vacation-Rentals.d177772.Travel-Guide-VacationRentals)
- [Florida Vacation Rentals ](https://www.expedia.com/Destinations-In-Florida.d211.Vacation-Rental-Destinations)
- [Hawaii Vacation Rentals ](https://www.expedia.com/Destinations-In-Hawaii.d213.Vacation-Rental-Destinations)
- [Michigan Vacation Rentals ](https://www.expedia.com/Destinations-In-Michigan.d224.Vacation-Rental-Destinations)

- [Vacation Homes in Southern Illinois ](https://expedia.com/Southern-Illinois-Private-Vacation-Homes.d6233859-aaPrivateVacationHomes.Travel-Guide-Accommodation)
- [Cabin Rentals in Southern Illinois ](https://expedia.com/Southern-Illinois-Cabins.d6233859-aaCabins.Travel-Guide-Accommodation)
- [Apartments in Southern Illinois ](https://expedia.com/Southern-Illinois-Apartments.d6233859-aaApartments.Travel-Guide-Accommodation)
- [Motels in Southern Illinois ](https://expedia.com/Southern-Illinois-Motels.d6233859-aaMotels.Travel-Guide-Accommodation)
- [Cottages in Southern Illinois ](https://expedia.com/Southern-Illinois-Cottages.d6233859-aaCottages.Travel-Guide-Accommodation)
- [RV Parks in Southern Illinois ](https://expedia.com/Southern-Illinois-RV-Parks.d6233859-aaRVParks.Travel-Guide-Accommodation)
- [Aparthotels in Southern Illinois ](https://expedia.com/Southern-Illinois-Apart-Hotels.d6233859-aaApartHotels.Travel-Guide-Accommodation)
- [Farmstay in Southern Illinois ](https://expedia.com/Southern-Illinois-Agritourism.d6233859-aaAgritourism.Travel-Guide-Accommodation)
- [Lodges in Southern Illinois ](https://expedia.com/Southern-Illinois-Lodges.d6233859-aaLodges.Travel-Guide-Accommodation)
- [B&B in Southern Illinois ](https://expedia.com/Southern-Illinois-Bed-And-Breakfast.d6233859-aaBedAndBreakfast.Travel-Guide-Accommodation)
- [Condo Rentals in Southern Illinois ](https://expedia.com/Southern-Illinois-Condos.d6233859-aaCondos.Travel-Guide-Accommodation)
- [Guest Houses in Southern Illinois ](https://expedia.com/Southern-Illinois-Guest-Houses.d6233859-aaGuestHouses.Travel-Guide-Accommodation)
- [Villas in Southern Illinois ](https://expedia.com/Southern-Illinois-Villas.d6233859-aaVillas.Travel-Guide-Accommodation)
- [Resorts in Southern Illinois ](https://expedia.com/Southern-Illinois-Resorts.d6233859-aaResorts.Travel-Guide-Accommodation)

### Expedia's Latest Trends

Hotels

- [Hotels with Suites in Northwest Chicago](https://expedia.com/Northwest-Chicago-Hotels-Hotel-Suites.0-0-d6350697-tHotelSuites.Travel-Guide-Filter-Hotels)
- [Luxury Hotels in Central Illinois](https://expedia.com/Central-Illinois-Hotels-Luxury-Hotel.0-0-d6059219-tLuxuryHotel.Travel-Guide-Filter-Hotels)
- [Family Hotels in Northern Illinois](https://expedia.com/Northern-Illinois-Hotels-Family-Hotel.0-0-d6058965-tFamilyHotel.Travel-Guide-Filter-Hotels)
- [Hotels in Northwest Chicago](https://expedia.com/Northwest-Chicago-Hotels.d6350697.Travel-Guide-Hotels)
- [Luxury Hotels in Western Suburbs](https://expedia.com/Western-Suburbs-Hotels-Luxury-Hotel.0-0-d6059325-tLuxuryHotel.Travel-Guide-Filter-Hotels)
- [Luxury Hotels in Northwest Chicago](https://expedia.com/Northwest-Chicago-Hotels-Luxury-Hotel.0-0-d6350697-tLuxuryHotel.Travel-Guide-Filter-Hotels)
- [Casinos in Northern Illinois](https://expedia.com/Northern-Illinois-Hotels-Casino-Hotel.0-0-d6058965-tCasinoHotel.Travel-Guide-Filter-Hotels)
- [Adults Only Resorts & Hotels in Central Illinois](https://expedia.com/Central-Illinois-Hotels-Adults-Only-Resorts.0-0-d6059219-tAdultsOnlyResorts.Travel-Guide-Filter-Hotels)
- [Extended Stay Hotels in Northwest Chicago](https://expedia.com/Northwest-Chicago-Hotels-Extended-Stay-Hotels.0-0-d6350697-tExtendedStayHotels.Travel-Guide-Filter-Hotels)
- [Hotels in Western Suburbs](https://expedia.com/Western-Suburbs-Hotels.d6059325.Travel-Guide-Hotels)
- [Luxury Hotels in South Suburbs](https://expedia.com/South-Suburbs-Hotels-Luxury-Hotel.0-0-d6264251-tLuxuryHotel.Travel-Guide-Filter-Hotels)
- [Hotels with an Indoor Pool in Western Suburbs](https://expedia.com/Western-Suburbs-Hotels-Hotels-With-Indoor-Pool.0-0-d6059325-tHotelswithIndoorPool.Travel-Guide-Filter-Hotels)
- [Drury Inn & Suites Hotels in Central Illinois](https://expedia.com/Central-Illinois-Hotels-Drury-Inn-Suites.0-0-d6059219--bDruryInnSuites.Travel-Guide-Filter-Hotels)
- [Hotels in South Suburbs](https://expedia.com/South-Suburbs-Hotels.d6264251.Travel-Guide-Hotels)

Cars

- [Priceless Car Rental Car Rentals In Northwest Chicago](https://expedia.com/Priceless-Car-Rental-Car-Rentals-In-Northwest-Chicago.d6350697-c1060.Car-Rental-Guide-Suppliers)
- [NU Car Rentals Car Rentals In Northwest Chicago](https://expedia.com/NU-Car-Rentals-Car-Rentals-In-Northwest-Chicago.d6350697-c71.Car-Rental-Guide-Suppliers)
- [Firefly EU Car Rentals In Northwest Chicago](https://expedia.com/Firefly-EU-Car-Rentals-In-Northwest-Chicago.d6350697-c1054.Car-Rental-Guide-Suppliers)
- [Car rentals in Northwest Chicago](https://expedia.com/Car-Rentals-In-Northwest-Chicago.d6350697.Car-Rental-Guide)
- [OK Mobility Car Rentals In Northwest Chicago](https://expedia.com/OK-Mobility-Car-Rentals-In-Northwest-Chicago.d6350697-c1057.Car-Rental-Guide-Suppliers)

Activities

- [Things to do in Western Illinois](https://expedia.com/Things-To-Do-In-Western-Illinois.d6058920.Travel-Guide-Activities)
- [Things to do in Northwest Chicago](https://expedia.com/Things-To-Do-In-Northwest-Chicago.d6350697.Travel-Guide-Activities)
- [Things to do in Central Illinois](https://expedia.com/Things-To-Do-In-Central-Illinois.d6059219.Travel-Guide-Activities)
- [Things to do in Northern Illinois](https://expedia.com/Things-To-Do-In-Northern-Illinois.d6058965.Travel-Guide-Activities)

General

- [Visit Western Illinois](https://expedia.com/Western-Illinois.dx6058920)
- [Visit Southeast Illinois](https://expedia.com/Southeast-Illinois.dx6058934)
- [Where to stay in Northwest Chicago](https://expedia.com/Northwest-Chicago.dx6350697.Where-To-Stay)
- [Visit Northern Illinois](https://expedia.com/Northern-Illinois.dx6058965)
- [Visit Western Suburbs](https://expedia.com/Western-Suburbs.dx6059325)
- [Visit Central Illinois](https://expedia.com/Central-Illinois.dx6059219)
- [Visit Southwest Illinois](https://expedia.com/Southwest-Illinois.dx6058943)

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