A forested valley with autumn foliage, a rocky cliff, and a sunset.

Southern Illinois Vacation Rentals

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Our top choices for Southern Illinois vacation rentals

1. Pet Friendly! Couples Retreat in Southern Illinois

Pet Friendly! Couples Retreat in Southern Illinois
3.0 star property
Murphysboro
$212 nightly
The price is $235
Nov 16 - Nov 17
Total with taxes and fees
Pet Friendly! Couples Retreat in Southern Illinois

2. Illinois Vacation Rental Home: Pets Welcome

Illinois Vacation Rental Home: Pets Welcome
3.0 star property
Palestine
10.0 out of 10, Exceptional, (1 review)
$327 nightly
The price is $346
Nov 23 - Nov 24
Total with taxes and fees
Illinois Vacation Rental Home: Pets Welcome

3. Pet Friendly! Countryside Couples Stay in Illinois

Pet Friendly! Countryside Couples Stay in Illinois
2.5 star property
Murphysboro
$218 nightly
The price is $242
Nov 22 - Nov 23
Total with taxes and fees
Pet Friendly! Countryside Couples Stay in Illinois

4. Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy

Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy
2.0 star property
French Village
10.0 out of 10, Exceptional, (121 reviews)
"Recomend this location"
United States
Jose
$128 nightly
The price is $145
Dec 14 - Dec 15
Total with taxes and fees
Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy

5. White House at Grand Central

White House at Grand Central
3.5 star property
Grand Center
8.2 out of 10, Very good, (170 reviews)
"Very spacious clean old house apartments"
United States
Priscilla
$116 nightly
The price is $129
Nov 16 - Nov 17
Total with taxes and fees
White House at Grand Central

6. The Atrium - A Boutique Hotel

The Atrium - A Boutique Hotel
2.0 star property
Perryville
9.6 out of 10, Exceptional, (16 reviews)
"Great place to stay"
United States
Matt
$98 nightly
The price is $112
Nov 16 - Nov 17
Total with taxes and fees
The Atrium - A Boutique Hotel

7. Urban Lofts

Urban Lofts
3.0 star property
Perryville
9.4 out of 10, Exceptional, (22 reviews)
"Beautiful place and staff was amazing!"
United States
Grace
$295 nightly
The price is $338
Nov 16 - Nov 17
Total with taxes and fees
Urban Lofts

8. Tiny Houses of French Village

Tiny Houses of French Village
2.5 star property
French Village
10.0 out of 10, Exceptional, (6 reviews)
"Very nice place very clean well kept inside an out it's a nice little romantic getaway they have it set up so great its a must see sunset very relaxing "
United States
Chris
$347 nightly
The price is $370
Nov 16 - Nov 17
Total with taxes and fees
Tiny Houses of French Village

9. Quiet Country Stay: Modern Home Near Paducah

Quiet Country Stay: Modern Home Near Paducah
3.0 star property
Cunningham
$271 nightly
The price is $290
Nov 23 - Nov 24
Total with taxes and fees
Quiet Country Stay: Modern Home Near Paducah
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Southern Illinois Hotel Reviews

Find out more about Southern Illinois

Everything you need to know about Southern Illinois vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Southern Illinois vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Southern Illinois vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Southern Illinois vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Southern Illinois. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Southern Illinois in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $107 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on Southern Illinois rentals

At Expedia, we put the best Southern Illinois vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Southern Illinois rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Southern Illinois vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Southern Illinois. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

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