Find hotels in Clayton, St. Louis from $76

Most hotels are fully refundable. Because flexibility matters.

Save 10% or more on over 100,000 hotels worldwide as a One Key member.

Search over 2.9 million properties and 550 airlines worldwide.

Find properties with these dates

Tonight
May 13 - May 14
Tomorrow
May 14 - May 15
This weekend
May 17 - May 19
Next weekend
May 24 - May 26

Filter by

Popular filters
Popular filters
Guest rating
Guest rating
Star rating
Payment type
Payment type
Property type
Property type
Neighborhood
Neighborhood
Popular locations
Popular locations
Meal plans available
Meal plans available
Amenities
Amenities
Accessibility
Accessibility
Traveler experience
Traveler experience

Discover 2,090 Clayton hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

Hollywood Casino & Hotel St. Louis
Front of property - evening/night
Hollywood Casino & Hotel St. Louis
3.5 star property
8.2 out of 10, Very Good, (1189)
"I love this place. Everything is nice"
The price is $104
$131 total
includes taxes & fees
May 27 - May 28
Hollywood Casino & Hotel St. Louis
Sonesta ES Suites St. Louis - Chesterfield
Studio Suite, 1 King Bed | Blackout drapes, soundproofing, iron/ironing board
Sonesta ES Suites St. Louis - Chesterfield
3.0 star property
8.2 out of 10, Very Good, (1005)
"Just what we needed. Having 2 bathrooms was amazing!"
The price is $100
$116 total
includes taxes & fees
May 29 - May 30
Sonesta ES Suites St. Louis - Chesterfield
Best Western St. Louis-Kirkwood Route 66
Lobby
Best Western St. Louis-Kirkwood Route 66
2.5 star property
8.8 out of 10, Excellent, (1011)
"Always a great stay here!"
The price is $119
$139 total
includes taxes & fees
May 14 - May 15
Best Western St. Louis-Kirkwood Route 66
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free
St. Louis Airport Hotel
Front of property
St. Louis Airport Hotel
3.5 star property
7.4 out of 10, Good, (602)
"Nice "
The price is $103
$122 total
includes taxes & fees
May 19 - May 20
St. Louis Airport Hotel
Home2 Suites by Hilton St. Louis/Forest Park
Dining room
Home2 Suites by Hilton St. Louis/Forest Park
3.0 star property
8.8 out of 10, Excellent, (1004)
"Staff was awesome enjoy our one day stay."
The price is $139
$162 total
includes taxes & fees
Jun 3 - Jun 4
Home2 Suites by Hilton St. Louis/Forest Park
Marriott St. Louis Airport
Property amenity
Marriott St. Louis Airport
4.0 star property
7.8 out of 10, Good, (1003)
"Clean rooms refrigerator. No microwave "
The price is $98
$117 total
includes taxes & fees
Jun 7 - Jun 8
Marriott St. Louis Airport
Hampton Inn & Suites St. Louis at Forest Park
Exterior
Hampton Inn & Suites St. Louis at Forest Park
2.5 star property
9.4 out of 10, Exceptional, (1003)
"Liked everything"
The price is $135
$159 total
includes taxes & fees
May 27 - May 28
Hampton Inn & Suites St. Louis at Forest Park
Drury Inn & Suites St. Louis Forest Park
Lobby
Drury Inn & Suites St. Louis Forest Park
3.0 star property
9.2 out of 10, Wonderful, (1002)
"Liked the amazing hot breakfast. Nothing we didn't like but if i had to find something...for the price i paid i would have liked a room looking outside not facing inward toward a wall."
The price is $130
$153 total
includes taxes & fees
May 30 - May 31
Drury Inn & Suites St. Louis Forest Park
Comfort Inn St. Louis - Westport Event Center
Bar (on property)
Comfort Inn St. Louis - Westport Event Center
3.0 star property
7.4 out of 10, Good, (1006)
"Reasonable price for a clean room. Breakfast was as expected. No problems with anything. "
The price is $80
$93 total
includes taxes & fees
May 19 - May 20
Comfort Inn St. Louis - Westport Event Center
Hampton Inn St. Charles St. Peters
Exterior
Hampton Inn St. Charles St. Peters
2.5 star property
8.2 out of 10, Very Good, (1007)
"Nice place to stay "
The price is $110
$126 total
includes taxes & fees
May 27 - May 28
Hampton Inn St. Charles St. Peters
Courtyard by Marriott St Louis Creve Coeur
Terrace/patio
Courtyard by Marriott St Louis Creve Coeur
3.0 star property
8.6 out of 10, Excellent, (1002)
"Property is great and works well for any type of traveler. Their renovations are ongoing and affects a few opportunities."
The price is $144
$167 total
includes taxes & fees
May 26 - May 27
Courtyard by Marriott St Louis Creve Coeur
Country Inn & Suites by Radisson, St. Charles, MO
Desk, laptop workspace, blackout drapes, iron/ironing board
Country Inn & Suites by Radisson, St. Charles, MO
2.5 star property
9.4 out of 10, Exceptional, (1007)
"Lovely hotel and great front desk staff! Very comfortable bed & room! Breakfast was just ok, but I’d stay here again when visiting old St Charles."
The price is $135
$156 total
includes taxes & fees
Jun 2 - Jun 3
Country Inn & Suites by Radisson, St. Charles, MO
Sonesta Simply Suites St Louis Earth City
Desk, laptop workspace, blackout drapes, iron/ironing board
Sonesta Simply Suites St Louis Earth City
2.0 star property
8.6 out of 10, Excellent, (560)
"Very friendly staff. Fantastic bargain. Would stay here again."
The price is $104
$119 total
includes taxes & fees
May 20 - May 21
Sonesta Simply Suites St Louis Earth City
Courtyard by Marriott St Louis Westport Plaza
Terrace/patio
Courtyard by Marriott St Louis Westport Plaza
3.0 star property
8.8 out of 10, Excellent, (1002)
"Staff -very nice. Room was great as well"
The price is $142
$165 total
includes taxes & fees
May 26 - May 27
Courtyard by Marriott St Louis Westport Plaza
Red Roof Inn PLUS+ St Louis - Forest Park/ Hampton Ave 
Lobby
Red Roof Inn PLUS+ St Louis - Forest Park/ Hampton Ave 
2.5 star property
6.0 out of 10, (1004)
"Good place to stay"
The price is $76
$89 total
includes taxes & fees
May 20 - May 21
Red Roof Inn PLUS+ St Louis - Forest Park/ Hampton Ave 
DoubleTree by Hilton St. Louis Airport
In-room safe, desk, blackout drapes, iron/ironing board
DoubleTree by Hilton St. Louis Airport
4.0 star property
7.8 out of 10, Good, (509)
"Friendly staff and I liked that we could park our car there. "
The price is $118
$138 total
includes taxes & fees
May 19 - May 20
DoubleTree by Hilton St. Louis Airport
Holiday Inn Express & Suites St. Louis West - Fenton, an IHG Hotel
Indoor pool
Holiday Inn Express & Suites St. Louis West - Fenton, an IHG Hotel
3.0 star property
8.8 out of 10, Excellent, (1003)
"Mary did a fantastic job upon our arrival! Very professional along with a great personality! We are booking again in two weeks!"
The price is $132
$152 total
includes taxes & fees
May 16 - May 17
Holiday Inn Express & Suites St. Louis West - Fenton, an IHG Hotel
Hampton Inn & Suites Clayton/St. Louis-Galleria Area
Outdoor dining
Hampton Inn & Suites Clayton/St. Louis-Galleria Area
3.0 star property
9.0 out of 10, Wonderful, (720)
"A1"
The price is $152
$179 total
includes taxes & fees
May 28 - May 29
Hampton Inn & Suites Clayton/St. Louis-Galleria Area
Hilton Garden Inn St. Louis Airport
Reception
Hilton Garden Inn St. Louis Airport
3.0 star property
8.4 out of 10, Very Good, (1000)
"Great place"
The price is $131
$154 total
includes taxes & fees
May 27 - May 28
Hilton Garden Inn St. Louis Airport
Candlewood Suites St Louis St Charles, an IHG Hotel
Suite, 2 Bedrooms | Premium bedding, down comforters, pillowtop beds, in-room safe
Candlewood Suites St Louis St Charles, an IHG Hotel
2.5 star property
7.6 out of 10, Good, (638)
"Best hotel in St. Charles."
The price is $99
$114 total
includes taxes & fees
May 16 - May 17
Candlewood Suites St Louis St Charles, an IHG Hotel
Don't see what you're looking for?
See all available properties in Clayton
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighborhoods around Clayton

Hotels in top St. Louis neighborhoods Learn more about Clayton
Meeting of the Waters Fountain showing a statue or sculpture and a fountain

Downtown St. Louis

2 out of top 10 points of interest in this area
4/5(4,004 area reviews)

Head to the heart of the largest city in Missouri for its cultural hotspots, nightlife and a colossal monument that towers over the Mississippi River.

Find hotels in Downtown St. Louis

Clayton Travel Info

Number of reviews
18,221
Location
St. Louis, United States of America
Similar neighborhoods
Downtown St. Louis, Downtown West and Central West End
Accommodation
2,090 hotels
Lowest price
$76
Highest price
$152

Frequently asked questions

What's it like in Clayton?

Clayton is a welcoming neighborhood known for its array of dining options and sporting events. Consider a visit to Chapel of St. Timothy And St. Titus, Concordia Seminary as part of your Clayton travel plans.

Where is the best hotel for a stay in Clayton?

Based on Expedia customer reviews, Residence Inn By Marriott St. Louis Clayton is the highest ranked property in Clayton. This hotel offers free breakfast and a bar. Other top choices in the neighborhood include The Ritz-Carlton, St. Louis and Le Méridien St. Louis Clayton.

How many hotels can I expect to find in Clayton?

With 11 Expedia hotels and other accommodations in Clayton to choose from, this is a good starting point for exploring the greater St. Louis area.

If I need to cancel my hotel reservation in Clayton, will I receive a refund?

Yes, you'll find most room reservations are fully refundable if cancelled before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of the scheduled arrival. If you booked a non-refundable reservation, you may still be able to cancel and get a refund within 24 hours of your booking. Add your dates and click on "Search", then filter by "fully refundable" to view the best options available in Clayton.

Where can I learn more about changing or cancelling my trip to Clayton?

To find more details about rescheduling or cancelling your trip to Clayton, click here.

What are the top things to see and do in Clayton?

Chapel of St. Timothy And St. Titus, Concordia Seminary is an attraction you might want to check out while you're in Clayton. When you're sightseeing in St. Louis, St. Louis Zoo and Center of Creative Arts are also worth a stop.

How can I get around Clayton and the greater St. Louis area?

Ready to get out and explore the city? Clayton Station is the closest metro station.

Recent reviews of Clayton hotels

Pear Tree Inn St. Louis Airport

Pear Tree Inn St. Louis Airport

5/5 Excellent
"Check in was a breeze. The room was clean and bed comfortable. Tub came in handy for a long soak. Ron the gentleman serving at Happy Hour was phenomenal!! Great service wonderful personality. Breakfast was good. A very nice stay."
A verified traveler stayed at Pear Tree Inn St. Louis Airport
Posted 15 hours ago
Pear Tree Inn St. Louis Airport