Defiance Vacation Rentals

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Our top choices for Defiance vacation rentals

Cabin in Augusta

Adorable Augusta Cabin
9.0 out of 10, Wonderful, (9 reviews)
"Absolutely beautiful area. Cabin is so cozy"
United States
Aaron
$179 nightly
The price is $200
Jan 11 - Jan 12
Total with taxes and fees
Adorable Augusta Cabin
10.0 out of 10, Exceptional, (45 reviews)
"Lovely owner, cute little home. Fresh baked cookies, nice and clean bed was a bit too soft for us, personal preference. Very quiet and respectful owner's. Loved the birds/nature."
United States
Denise K.
$137 nightly
The price is $137
Jan 17 - Jan 18
Total with taxes and fees
TJ’s Country Getaway- Dog Friendly
9.6 out of 10, Exceptional, (13 reviews)
"Lovely weekend- enjoyed checking out Innsbrook"
United States
Denise L.
$214 nightly
The price is $220
Jan 11 - Jan 12
Total with taxes and fees
Aspen Sights by Innsbrook Vacations!
9.8 out of 10, Exceptional, (23 reviews)
"Everything was extremely clean. We couldn’t have asked for a more quiet and relaxing stay. "
United States
Brian L.
$214 nightly
The price is $220
Jan 11 - Jan 12
Total with taxes and fees
Lake Aspen Overlook by Innsbrook Vacations!
9.4 out of 10, Exceptional, (10 reviews)
"Great clubhouse, plenty of wildlife roaming grounds, and friendly atmosphere."
United States
tony
$214 nightly
The price is $220
Jan 11 - Jan 12
Total with taxes and fees
Serene Seebach Sights by Innsbrook Vacations!
9.6 out of 10, Exceptional, (18 reviews)
"Great location and property within close distance of all Innsbrook has to offer. Would stay again. "
United States
Kristina U.
$214 nightly
The price is $220
Jan 11 - Jan 12
Total with taxes and fees
The Harris Overlook by Innsbrook Vacations!
9.0 out of 10, Wonderful, (10 reviews)
"Nice, quiet, relaxing place to stay! Great communication with the host. "
United States
Lorna M.
$214 nightly
The price is $220
Jan 11 - Jan 12
Total with taxes and fees
Aspen Heights by Innsbrook Vacations!
7.0 out of 10, Good, (2 reviews)
"Great location, clean and plenty of space. Lots of amenities to use during our stay, canoes, fishing gear, video games. Could be updated a little. Baking supplies to make breakfast. "
United States
Nancy P.
$214 nightly
The price is $220
Jan 11 - Jan 12
Total with taxes and fees
The Aspen Hideout Pt.II by Innsbrook Vacations!
9.8 out of 10, Exceptional, (21 reviews)
"Check-in was easy and property was clean. Great place to stay!"
United States
Casey A.
$214 nightly
The price is $220
Jan 11 - Jan 12
Total with taxes and fees
Lake Aspen Hideaway by Innsbrook Vacations!
8.6 out of 10, Excellent, (12 reviews)
"Great property! Will rent again."
United States
donald j.
$215 nightly
The price is $221
Jan 12 - Jan 13
Total with taxes and fees
Aspen Hideout by Innsbrook Vacations!
9.8 out of 10, Exceptional, (12 reviews)
"Good Stay"
United States
Lanai
$237 nightly
The price is $237
Jan 14 - Jan 15
Total with taxes and fees
Sunny SparkingClean King bed Apt- CreveCoeurPark
9.8 out of 10, Exceptional, (41 reviews)
"It was very peaceful and close to all the activities we wanted to do like kayak fish and enjoy dinner looking out at the golf course. "
United States
Mollie L.
$182 nightly
The price is $188
Jan 11 - Jan 12
Total with taxes and fees
Studio Condo on the Water @ Innsbrook
9.2 out of 10, Wonderful, (5 reviews)
"I booked this place wit spend some homely time with my kids and it was amazing, the place was clean they even dropped off some extra towels without us having to ask, it was truly amazing. Will definitely stay there again. "
United States
teresa s.
$241 nightly
The price is $269
Jan 11 - Jan 12
Total with taxes and fees
Rustic Augusta Cabin by StayLage

Vacation Home in Saint Charles

Saint Charles 2 Bedroom Townhome by StayLage
9.0 out of 10, Wonderful, (8 reviews)
"We were very happy with our experience. Everything was as advertised, all of the basics were covered for us. Great place to stay. Thanks"
United States
bill r.
Saint Charles 2 Bedroom Townhome by StayLage

Vacation Home in O'Fallon

Quaint and Cozy Hamlet
9.6 out of 10, Exceptional, (14 reviews)
"Overall great time- communication was wonderful with Kevin, neighborhood was quiet, perfect for our stay. The house wasn’t as clean as I’d expect but besides that, great stay!"
United States
Madison A.
$359 nightly
The price is $369
Jan 12 - Jan 13
Total with taxes and fees
Quaint and Cozy Hamlet
9.2 out of 10, Wonderful, (12 reviews)
"This was a great spot for me and my granddaughter to stay. Within walking distance to the beach. It was clean, quiet and even during the rain there were puzzles and some games available to play. Nicely decorated. "
United States
Jaime S.
$214 nightly
The price is $220
Jan 11 - Jan 12
Total with taxes and fees
Lake Aspen Landing by Innsbrook Vacations!
2.0 star property
10.0 out of 10, Exceptional, (4 reviews)
"Everything was perfect!!"
United States
Rochelle T.
$355 nightly
The price is $366
Jan 11 - Jan 12
Total with taxes and fees
Lakefront Lodge by Innsbrook Vacations!
10.0 out of 10, Exceptional, (12 reviews)
"Great place, nice neighborhood. "
United States
Julie L.
$280 nightly
The price is $280
Jan 12 - Jan 13
Total with taxes and fees
The Hidden Gem - 2BR Basement Apartment on 7 Acres

Vacation Home in St. Charles Historic District

Madison House 1 -Walk to Main St
8.6 out of 10, Excellent, (16 reviews)
"The house was clean and well stocked, location was great, and plenty of street parking. "
United States
Brad K.
$209 nightly
The price is $235
Jan 11 - Jan 12
Total with taxes and fees
Madison House 1 -Walk to Main St
9.2 out of 10, Wonderful, (7 reviews)
"Nice ,comfortable 2 bedroom condo on lake. Beach is easy walk from condo, pool is a short drive to community center. Beautiful lakefront views with deer ,foxes, and lots of birds. Would stay here again"
United States
jennifer m.
$356 nightly
The price is $367
Jan 11 - Jan 12
Total with taxes and fees
Cozy Condo on Lake Aspen by Innsbrook Vacations!
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Defiance Hotel Reviews

Find out more about Defiance

Everything you need to know about Defiance vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Defiance vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Defiance vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Defiance vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Defiance. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Defiance in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $227 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on Defiance rentals

At Expedia, we put the best Defiance vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Defiance rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Defiance vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Defiance. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Frequently asked questions

Can I find vacation rentals in Defiance?

Yes, there are vacation rentals close to popular sights in Defiance, or you can choose a more secluded option if you're looking for relaxation. Defiance is known for its wineries and parks.

What are some of the best vacation home rentals that Defiance has to offer?

The St. Charles Guest House, lovely historic home, fun for families and groups: This vacation home rental outside of Defiance is located on a river and has a fireplace, a selection of games, and air-conditioning to put you at ease in your new surroundings. It has 3 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family.

How many vacation rentals will I find in Defiance?

With 4 Expedia vacation rentals, you're sure to find just the right place for your Defiance stay.

What’s there to see and do in Defiance?

Matson Hill Park Trailhead and August A. Busch Memorial Conservation Area are a couple of scenic spots to enjoy the outdoors, whereas Historic Daniel Boone Home and Heritage Center is one of the cultural attractions. Other places in town to visit include Yellow Farmhouse Winery and Chandler Hill Vineyards.

What’s a vacation rental in Defiance like?

A vacation rental is a private property where you can stay for a few weeks or just a few days in Defiance. Vacation rentals feature amenities like laundry facilities and kitchens so your stay will be comfortable. If you're concerned about cleanliness, vacation rentals can offer a sense of security away from shared hotel elevators and busy front desks while still allowing you a great travel experience. You'll also get more space in a vacation rental than in a traditional hotel, which makes a vacation rental a great option for families.