Defiance, MO
Travel Guide
Visit Defiance
Hollywood Casino & Hotel St. Louis
777 Casino Center Drive Maryland Heights MO
$133 nightly
The price is $156 total per night from Aug 30 to Aug 31
$156 total
Aug 30 - Aug 31
Total with taxes and fees
Book a stay at this business-friendly hotel in Maryland Heights. Enjoy free parking, 7 restaurants, and a casino. Our guests praise the helpful staff and the ...
8.6/10 Excellent! (2,196 reviews)
"No problems, quick service and clean facilities. Would stay again if in the area."
Reviewed on Aug 5, 2026
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
1088 South Highway Drive Fenton MO
$91 nightly
The price is $105 total per night from Sep 6 to Sep 7
$105 total
Sep 6 - Sep 7
Total with taxes and fees
Book a stay at this business-friendly hotel in Fenton. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
Ameristar Casino Resort and Spa
1 Ameristar Blvd St. Charles MO
$174 nightly
The price is $203 total per night from Aug 9 to Aug 10
$203 total
Aug 9 - Aug 10
Total with taxes and fees
Book a stay at this luxury hotel in St. Charles. Enjoy a full-service spa, 6 restaurants, and a casino. Our guests praise the clean rooms in our reviews. Popular ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
The Lofts of North Main Street
Saint Charles MO
Stay at this apartment in St. Charles. Enjoy free WiFi, laundry facilities, and an in-room coffeemaker. Popular attractions Ameristar Casino St. Charles and ...
9.6/10 Exceptional! (183 reviews)
"Awesome place just as advertised. Home was clean and parking was great. Will definitely look to book this home again when in the area."
Reviewed on Jul 20, 2026
St. Charles 1860's Gem - Sleeps 6!
St Charles MO
Stay at this vacation home in St. Charles. Enjoy free WiFi, a garden, and laundry facilities. Popular attractions Ameristar Casino St. Charles and Hollywood ...
9.8/10 Exceptional! (158 reviews)
"It was a nice little place . Perfect for what I needed it for"
Reviewed on Jun 24, 2026
Woodland Retreat with a Swim Spa - Innsbrook Resort
Innsbrook MO
Book a stay at this golf chalet in Innsbrook. Enjoy free WiFi, a fitness center, and laundry facilities. Popular attractions Trautwein Lake and Kristel Lake ...
10/10 Exceptional! (12 reviews)
"We had a fantastic trip. The house was beautiful and had everything we needed. Paul was a great host, and was very communicative throughout the trip."
Reviewed on Aug 2, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Stay near popular Defiance attractions
Things to do
St. Louis Ghost Tour: Sinister Sins & Shadows
$24
per adult
100% of travellers recommend
StL's Signature "Sights and Bites" - Private Tour in St. Louis
$175
per adult
Lemp Haunted Neighborhood Walking Tour
$25
per adult
84% of travellers recommend
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- Visit St. Louis
- Visit Earth City
- Visit St. Peters
- Visit Wentzville
- Visit Saint Albans
- Visit Washington
- Visit Lake St Louis
- Visit New Melle
- Visit Creve Coeur
- Visit St. Charles Historic District
- Visit Ballwin
- Visit Maryland Heights
- Visit Eureka
- Visit Wright City
- Visit Marthasville
- Visit Gray Summit
- Visit Innsbrook
- Visit Wildwood
- Visit Kirkwood
- Visit O'Fallon
- Visit St. Charles
- Visit Chesterfield
- Sky Zone Indoor Trampoline Park - St. Louis
- Visit Downtown St. Louis
- St. Louis Zoo
- Visit Catawissa
- Visit Town and Country
- Visit Foristell
- Visit Des Peres
- Visit Valley Park
- Visit House Springs
- Visit Cottleville
- August A. Busch Memorial Conservation Area
- Chandler Hill Vineyards
- Historic Daniel Boone Home and Heritage Center
- Sugar Creek Winery
- Yellow Farmhouse Winery
- Broemmelsiek Park
- Six Flags St. Louis
- Mississippi River
- Ameristar Casino St. Charles
- Westport Plaza
- Hollywood Casino Amphitheatre
- Magic House - St. Louis Children's Museum
- Route 66 State Park
- St Charles Convention Center
- Lindenwood University
- Hollywood Casino
- Purina Farms
- St. Louis Premium Outlets
- The Factory
- Missouri River
- Historic Main Street
- Family Arena
- Mid Rivers Mall
- Fast Lane Classic Cars
- Lou Fusz Soccer Complex
- Hidden Valley Ski Resort
- National Equestrian Center
- Augusta Winery
- CarShield Field
- Meramec River