Search Vacation Homes in Buffalo

    price find illustration

    Upfront pricing

    Our total price for your stay includes taxes and fees
    deals illustration

    Treat yourself

    Save 10% or more on over 100,000 hotels worldwide with Member Prices
    Learn about One Key
    bed illustration

    Be picky

    Search almost a million properties worldwide

Check prices for these dates

Next weekend
Aug 22 - Aug 24
In two weeks
Aug 29 - Aug 31
In one month
Sep 12 - Sep 14
In two months
Oct 10 - Oct 12

Vacation Homes in Buffalo

Nature retreat on Enoree river
Property grounds

Nature retreat on Enoree river

10.0 out of 10, Exceptional, (64)
"Peaceful view of the river, extra clean, nicely equipped, great hosts!"
Nature retreat on Enoree river
Cozy Home off I-85, 35 minutes from NC and SC border
Terrace/patio

Cozy Home off I-85, 35 minutes from NC and SC border

9.8 out of 10, Exceptional, (30)
"Great place"
Cozy Home off I-85, 35 minutes from NC and SC border
Hub City Haven 2; Brand NEW-3 BR, 2 BA Home Near Tyger River Park & Downtown
Terrace/patio

Hub City Haven 2; Brand NEW-3 BR, 2 BA Home Near Tyger River Park & Downtown

10.0 out of 10, Exceptional, (9)
"Beautiful, new comfortable home! We loved our stay wish it would have been longer. Great location to everything you would need."
Hub City Haven 2; Brand NEW-3 BR, 2 BA Home Near Tyger River Park & Downtown
Beautiful Pet Friendly Home in Central Spartanburg Sleeps 6
Fridge, microwave, oven, stovetop

Beautiful Pet Friendly Home in Central Spartanburg Sleeps 6

10.0 out of 10, Exceptional, (74)
"Beautiful home! Wish I would have brought my dog's to play in the back yard, it's huge! Would definitely recommend."
Beautiful Pet Friendly Home in Central Spartanburg Sleeps 6
Band New Luxury Stay, 3 min to Downtown Sleeps 10
TV, offices

Band New Luxury Stay, 3 min to Downtown Sleeps 10

$286 nightly
The price is $315
Aug 18 - Aug 19
Total includes taxes and fees
Band New Luxury Stay, 3 min to Downtown Sleeps 10
Beautiful Home minutes from Downtown & BMW
Fridge, microwave, oven, stovetop

Beautiful Home minutes from Downtown & BMW

Beautiful Home minutes from Downtown & BMW
Joy for your Journey - 3-bedroom house in peaceful Spartanburg w/ WiFi, Kitchen
Private kitchen

Joy for your Journey - 3-bedroom house in peaceful Spartanburg w/ WiFi, Kitchen

10.0 out of 10, Exceptional, (2)
"We stayed four nights for college graduation in town. The house is very well stocked with all that we needed to provide for our large group. Comfortable setting, quiet neighborhood, and close to everything. "
Joy for your Journey - 3-bedroom house in peaceful Spartanburg w/ WiFi, Kitchen
1930's home, downtown- free cancellations
Exterior

1930's home, downtown- free cancellations

9.2 out of 10, Wonderful, (12)
"Love coming to this place to visit my daughter and her family. "
1930's home, downtown- free cancellations
~2 Bedroom Cozy Gem 💎 5 minutes from Downtown Spartanburg~
Exterior

~2 Bedroom Cozy Gem 💎 5 minutes from Downtown Spartanburg~

10.0 out of 10, Exceptional, (41)
"Spotless with huge private yard. Has almost every convenience - no icemaker so bring bagged ice if needed. Quick drive to downtown. "
$187 nightly
The price is $208
Aug 24 - Aug 25
Total includes taxes and fees
~2 Bedroom Cozy Gem 💎 5 minutes from Downtown Spartanburg~
Charming home- Dog Friendly, washer/dryer, internet access, and firepit
Fridge, microwave, oven, stovetop

Charming home- Dog Friendly, washer/dryer, internet access, and firepit

2.0 star property
8.8 out of 10, Excellent, (6)
"Loved the property "
Charming home- Dog Friendly, washer/dryer, internet access, and firepit
Baby Blue Bungalow with Backyard Oasis
Property grounds

Baby Blue Bungalow with Backyard Oasis

10.0 out of 10, Exceptional, (1)
"We had no issues with the house or check in. It’s very clean and in a nice neighborhood. It appears to be a new house. I would definitely recommend it and I would stay there again! "
$341 nightly
The price is $379
Aug 14 - Aug 15
Total includes taxes and fees
Baby Blue Bungalow with Backyard Oasis
Golfer's Heaven 4 bedroom home w/pool table
Outdoor dining

Golfer's Heaven 4 bedroom home w/pool table

10.0 out of 10, Exceptional, (2)
"In town visiting family and stayed here for a couple of days. The accommodations, and location were perfect. Easy access to downtown Greenville and Spartanburg. Would stay at this location again in a minute. Only regret is I didn’t have time to get a round of golf in. "
Golfer's Heaven 4 bedroom home w/pool table
Whole House, sleeps 7, within walking distance to downtown Spartanburg!
Property grounds

Whole House, sleeps 7, within walking distance to downtown Spartanburg!

2.0 star property
10.0 out of 10, Exceptional, (5)
"Accommodations were comfortable and had everything we needed. The location is great. "
$237 nightly
The price is $263
Sep 4 - Sep 5
Total includes taxes and fees
Whole House, sleeps 7, within walking distance to downtown Spartanburg!
Cozy Modern Duplex Near Downtown Spartanburg
Exterior

Cozy Modern Duplex Near Downtown Spartanburg

10.0 out of 10, Exceptional, (3)
"Great space with everything we could possibly have needed! Clean, lots of room and perfect for traveling with our golden retriever. "
Cozy Modern Duplex Near Downtown Spartanburg
Woodruff's Southern Nest, located few blocks from historic downtown Woodruff!
Fridge, microwave, oven, stovetop

Woodruff's Southern Nest, located few blocks from historic downtown Woodruff!

10.0 out of 10, Exceptional, (8)
"Nice property, had everything we needed. Thank You !"
Woodruff's Southern Nest, located few blocks from historic downtown Woodruff!
Modern & Peaceful 2BR Retreat-Newly Renovated Gem Just 20 Mins from Spartanburg
Outdoor dining

Modern & Peaceful 2BR Retreat-Newly Renovated Gem Just 20 Mins from Spartanburg

$250 nightly
The price is $273
Aug 14 - Aug 15
Total includes taxes and fees
Modern & Peaceful 2BR Retreat-Newly Renovated Gem Just 20 Mins from Spartanburg
Luxury Stay 2 min to Downtown, King Beds BRAND NEW
Dining

Luxury Stay 2 min to Downtown, King Beds BRAND NEW

9.0 out of 10, Wonderful, (2)
"Beautiful home owner was very responsive. We would stay here again!"
$286 nightly
The price is $315
Aug 18 - Aug 19
Total includes taxes and fees
Luxury Stay 2 min to Downtown, King Beds BRAND NEW
Downtown 1930's shingle home with color.
Exterior

Downtown 1930's shingle home with color.

9.6 out of 10, Exceptional, (18)
"Good place to stay. Take blankets with you. "
Downtown 1930's shingle home with color.
Cute Bungalow near Downtown, sleeps 6
Exterior

Cute Bungalow near Downtown, sleeps 6

Cute Bungalow near Downtown, sleeps 6
Cheerful Pet-Friendly Bungalow 1 Block from Downtown Laurens
Fridge, microwave, oven, stovetop

Cheerful Pet-Friendly Bungalow 1 Block from Downtown Laurens

10.0 out of 10, Exceptional, (17)
"Wonderful stay. Will definitely stay again when in town."
Cheerful Pet-Friendly Bungalow 1 Block from Downtown Laurens
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top Buffalo Hotel Reviews

Hampton Inn & Suites Spartanburg-I-26-Westgate Mall

Hampton Inn & Suites Spartanburg-I-26-Westgate Mall

10/10 Excellent
"Clean, great staff. Conveniently located to many shopping options and restaurants."
Brenda 2-night trip
Posted 3 days ago
Hampton Inn & Suites Spartanburg-I-26-Westgate Mall