Top 10 Hotels in Buffalo, SC (from $65) 2026 - Competitive Prices

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Our top choices for Buffalo hotels

A hotel room with two beds, a desk, a chair, a TV, and a window with curtains.

A motel with a single-story structure, a covered parking area, and a well-maintained lawn.

A hotel room with a wooden table, a black office chair, a black refrigerator, and a large mirror on the wall.

1. The Night Inn

Union

Robert

$70 nightly

$76 total

Oct 7 - Oct 8

Total with taxes and fees

A hotel room with a bed, a sofa, a nightstand, and a small table.

A row of residential buildings with a blue door, a white window, and a vent on the wall.

A rectangular pool with a blue border, surrounded by a black fence. There are lounge chairs and a small table with chairs along the poolside.

A reception area with a blue wall, a wooden counter, a glass door leading outside, and a potted plant.

2. Rodeway Inn Union

Union

Dejuana

$65 nightly

$70 total

Oct 26 - Oct 27

Total with taxes and fees

A hotel with a central entrance, multiple floors, and a flag display.

A hotel reception area with a modern reception desk, seating area, and large windows.

A hotel room with a desk, chair, bed, and a bathroom with a sink and mirror.

A breakfast buffet with various food items, coffee machines, and a toaster.

3. Comfort Suites Clinton near Presbyterian College

Clinton

alberto

$83 nightly

$93 total

Oct 26 - Oct 27

Total with taxes and fees

A modern living room with a sofa, armchairs, a patterned rug, and a Buddha statue.

A laundry room with a washing machine, dryer, chair, and table.

A conference room with tables and chairs, a television, and a whiteboard.

A hotel room with two beds, a sofa, a TV, and a window with curtains.

4. Days Inn by Wyndham Clinton / Laurens I-26

Clinton

Julian

$68 nightly

$76 total

Oct 18 - Oct 19

Total with taxes and fees

A hotel room with two beds, a desk, a bathroom, and a TV.

A home gym with a treadmill, stationary bike, bench, and dumbbells.

A modern hotel lobby with a seating area, a dining space, and a reception desk.

A restaurant with multiple tables and chairs, a kitchen area, and a wall with food images.

5. Quality Inn Clinton - Laurens I-26

Clinton

Tyiesha

$73 nightly

$81 total

Nov 1 - Nov 2

Total with taxes and fees

A modern indoor space with a sofa, tables, chairs, and a pool view.

A modern interior with a stone fireplace, wooden tables and chairs, and a large orange sofa.

A pool area with a clear view of the outdoors, including a patio with chairs and umbrellas.

A gym with treadmills, weight machines, and a mirror reflecting the equipment.

6. Hampton Inn & Suites Clinton - I-26

Clinton

Andrea

$135 nightly

$151 total

Oct 18 - Oct 19

Total with taxes and fees

A modern lobby with a reception desk, seating area, and a television screen.

A hotel with a covered entrance, brick exterior, and a sign indicating it is a Best Western hotel.

A swimming pool with lounge chairs and tables, surrounded by brick buildings and a covered seating area.

A hotel room with two beds, a desk with a lamp, a chair, a patterned rug, and a large window.

7. Best Western Spartanburg I-26

Spartanburg

Santhosh

$97 nightly

$108 total

Oct 18 - Oct 19

Total with taxes and fees

A bar area with a long counter, multiple stools, and shelves stocked with bottles.

A spacious lobby with a bar area, seating, and large windows.

A restaurant with a central island seating area, multiple tables, and a large mural on the wall.

An outdoor seating area with string lights, tables, and chairs at the Hilton Garden Inn.

8. Hilton Garden Inn Spartanburg

Spartanburg

Yuliya

$131 nightly

$145 total

Oct 30 - Oct 31

Total with taxes and fees

A hotel lobby with a curved outdoor seating area, a fire pit, and a pool.

A lobby with a stone fireplace, sofas, a TV mounted on the wall, and a bar area in the background.

A grand hotel lobby with a marble staircase, ornate carpet, and large landscape paintings on the walls.

A spacious lobby with a high ceiling, chandeliers, a registration desk, and potted plants.

9. Spartanburg Marriott

Spartanburg

Daniel

$118 nightly

$131 total

Oct 25 - Oct 26

Total with taxes and fees

An outdoor seating area with sofas, a fire pit, and string lights.

A self-service kiosk with a variety of snacks and beverages, a microwave, and a refrigerated display.

A modern hotel with a multi-story structure, large windows, and a prominent vertical light strip.

A modern lounge area with seating arrangements, a large window offering a view of the outdoors, and contemporary lighting fixtures.

10. Tru by Hilton Spartanburg

Spartanburg

Anthony

$106 nightly

$117 total

Nov 1 - Nov 2

Total with taxes and fees

A modern hotel lobby with a long reception desk, bar area with stools, seating with patterned cushions, and a large window offering a view of greenery.

A Holiday Inn Express hotel with a covered entrance, brick facade, and large windows.

A hotel room with a kitchenette, two beds, a red sofa, and a dining area.

A vending area with various snack and drink options, including chips, sodas, and bottled water.

11. Holiday Inn Express I-26 & Us 29 At Westgate Mall by IHG

Spartanburg

Amy

$109 nightly

$121 total

Oct 18 - Oct 19

Total with taxes and fees

A rooftop bar with seating, a bar area, and a view of the cityscape at dusk.

A modern living room with a dark-colored sofa, armchairs, a coffee table, and a bookshelf filled with decorative items.

A modern restaurant with a bar area, high ceilings, and a view of the cityscape.

A spacious living area with a modern sofa, armchairs, a coffee table, and a dining area with chairs and a table.

12. AC Hotel by Marriott Spartanburg

Spartanburg

Willow

$169 nightly

$188 total

Oct 11 - Oct 12

Total with taxes and fees

A two-story building with a red roof and a sign for Red Roof Inn & Suites.

A vending machine with snacks and a drink dispenser.

A two-story Red Roof Inn with a flat roof, multiple windows, and a sign indicating it offers suites.

A laundry room with two washing machines and a dryer, a door, and a tiled floor.

13. Red Roof Inn Spartanburg - I-85

Spartanburg

Walker

$58 nightly

$65 total

Oct 12 - Oct 13

Total with taxes and fees

A dining area with tables and chairs, a television mounted on the wall, and a kitchen area with appliances.

A Rodeway Inn with a two-story building, a parking lot, and a few cars parked in front.

A hotel room with patterned green sofas, a wooden table, and a green wall.

A hotel room with a bed, a desk with a computer, a chair, a lamp, and a view of the outdoors through a window.

14. Rodeway Inn Laurens

Laurens

Ellamae

$69 nightly

$78 total

Oct 29 - Oct 30

Total with taxes and fees

A modern living room with a stone accent wall, a flat-screen TV, and a blue abstract rug.

A modern lobby with a sofa, armchairs, and a coffee table. There is a reception desk and a dining area in the background.

A hotel room with two beds, a desk with a chair, a TV, and a window with curtains.

A modern dining area with wooden flooring, round tables, and chairs. There are wall-mounted artworks and a sign that reads "LESS MONDAY MORE SUMMER".

15. Fairfield by Marriott Inn & Suites Spartanburg Downtown

Spartanburg

Zachary

$131 nightly

$145 total

Oct 11 - Oct 12

Total with taxes and fees

A modern kitchen with a central island, equipped with a microwave, toaster, and coffee machine.

A modern lobby with blue sofas, a reception desk, and a glass coffee table.

A hotel room with a bed, a gray sofa, two ottomans, a window with a view, and abstract artwork on the wall.

A hotel room with a desk, office chair, sofa, and a large wall art piece.

16. Comfort Suites At WestGate Mall

Spartanburg

tara

$91 nightly

$101 total

Nov 1 - Nov 2

Total with taxes and fees

A hotel room with two beds, a kitchenette, a TV, and a bathroom visible through an open door.

A hotel with a covered entrance, a parking lot, and a row of rooms with a green roof.

17. Suburban Studios Spartanburg - I-26

Spartanburg

Tammy

$85 nightly

$94 total

Oct 7 - Oct 8

Total with taxes and fees

A modern kitchen with a central island, bar stools, and pendant lighting.

A large indoor swimming pool with clear water, surrounded by lounge chairs and tables, and equipped with safety signage.

A hotel lobby with a reception desk, seating area, and large windows.

A modern hotel with a well-maintained lawn, brick pathway, and a row of white flowers.

18. Hampton Inn & Suites Spartanburg-I-26-Westgate Mall

Spartanburg

Melinda

$114 nightly

$127 total

Oct 25 - Oct 26

Total with taxes and fees

A hotel room with a bed, a desk with a computer, a television, and a microwave.

A bathroom with a bathtub, shower curtain, and marble wall tiles.

A single-story motel with a flat roof, large windows, and a small porch area.

A bedroom with a bed, wooden headboard, bedside tables, and a ceiling light.

19. SUN AND SAND MOTEL

Spartanburg

Jeffrey

$64 nightly

$71 total

Oct 13 - Oct 14

Total with taxes and fees

A modern hotel building with the name 'ECHO SUITES' prominently displayed.

A modern hotel lobby with glass doors, a reception desk, and a view of the outdoors.

A hotel room with a bed, a desk, a chair, a kitchenette, and a wardrobe.

A reception area with a wooden reception desk, a bench, and large windows with a view of the outside.

20. ECHO Suites Extended Stay by Wyndham Spartanburg

Spartanburg

Alphonse

$115 nightly

$128 total

Oct 8 - Oct 9

Total with taxes and fees

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Where to stay near Buffalo

Buffalo offers a charming blend of outdoor adventures and scenic beauty. Explore lush parks, enjoy romantic lakeside strolls, or indulge in wellness retreats. Nearby towns provide a friendly atmosphere, perfect for family outings and cultural experiences, making it an ideal getaway for relaxation and rejuvenation.

A neoclassical courthouse with a dome and columns, a flagpole, and a parked car in front.

A large brick building with white columns and a central entrance.

A large tree with moss-covered branches and a floral wreath at its base.

A set of stone steps leading to a gated entrance with a wrought iron gate.

Union

For travelers seeking a blend of nature and history, Union is the perfect base to explore the charm of South Carolina. This welcoming city offers access to the scenic Rose Hill Plantation State Historic Site, the tranquil Veterans Memorial Park, and the engaging Union County Museum, ensuring a rich experience for families and nature enthusiasts alike. Located about 4 miles from Buffalo, Union provides a smart choice for those looking to immerse themselves in local culture while enjoying outdoor activities.

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Monarch Mill

Plan your stay in Monarch Mill, a great choice for travelers seeking a blend of business, family, and outdoor adventures. This charming village is near attractions like Veterans Memorial Park, perfect for relaxation, and the Union County Museum, where history comes alive. For a taste of local heritage, don’t miss the Rose Hill Plantation State Historic Site. Located about 6 miles from Buffalo, Monarch Mill is an ideal spot for a memorable getaway.

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Jonesville

If you are a family or nature enthusiast, look no further than Jonesville, a charming city known for its inviting parks and recreational activities. Enjoy the serene landscapes at Croft State Park or unwind at the urban charm of Veterans Memorial Park, both perfect for outdoor adventures. With easy access to local shopping and golf courses, you’ll find plenty to explore. Located about 8 miles from Buffalo, Jonesville is an ideal choice for a delightful stay.

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Pauline

Immerse yourself in Pauline, where travelers with a penchant for family outings and nature adventures can easily access scenic spots and recreational activities. Enjoy the rich history at Walnut Grove Plantation, explore the natural beauty of Croft State Park, and unwind at Tyger-10 Nature Park. With its charm and variety, Pauline serves as a delightful base for your exploration of the surrounding area. Located about 10 miles from Buffalo, it’s a smart choice for your next getaway.

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Cross Anchor

Travelers looking for a charming getaway will find Cross Anchor to be the ideal base for their vacation, featuring a blend of family-friendly activities and beautiful natural scenery. This welcoming city is perfect for those seeking outdoor adventures and romantic escapes, with highlights like the Musgrove Mill State Historic Site and the nearby lake for leisurely days. With Cross Anchor just about 11 miles from Buffalo, it offers a smart choice for a budget-friendly stay while enjoying local attractions and experiences.

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Stay near popular attractions around Buffalo

Buffalo, South Carolina, offers a delightful blend of outdoor adventures and romantic scenery. Explore the charming urban parks, historic houses, and a welcoming library. Whether you're seeking family fun or a serene city experience, Buffalo is the perfect base for unforgettable memories and exploration.

Musgrove Mill State Historic Site

8.6/10 (19 reviews)

A fascinating mix of history and nature awaits outdoor enthusiasts at Musgrove Mill State Historic Site. This National Park features scenic landscapes and opportunities for adventure, showcasing the site’s rich Revolutionary War heritage. Located about 13 miles from Buffalo, it’s a convenient stop for a memorable day trip.

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Veterans Memorial Park

9.0/10 (11 reviews)

Set the stage for your family getaway at Veterans Memorial Park, an inviting urban park in Union, South Carolina. Embrace the outdoors with its vibrant atmosphere, perfect for picnics and leisurely strolls. Located about 4 miles from Buffalo, this park offers easy access, making it a convenient stop for your vacation adventures.

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Union County Museum

7.6/10 (8 reviews)

Ideal for history buffs, Union County Museum offers a rich glimpse into the local culture and heritage of Union, South Carolina. Located about 3 miles from Buffalo, this museum showcases fascinating exhibits that tell the story of the region. Staying nearby allows easy access to this cultural gem.

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Rose Hill Plantation State Historic Site

8.8/10 (6 reviews)

Ideal for travelers interested in history and culture, Rose Hill Plantation State Historic Site offers a glimpse into South Carolina's rich past. Located about 8 miles from Buffalo, visitors can explore its beautifully preserved grounds and learn about plantation life, making it a convenient and enriching stop on your journey.

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Battle of Blackstock Marker

8.0/10 (2 reviews)

Visitors often appreciate how this spot delivers a glimpse into the rich history of the Revolutionary War. The Battle of Blackstock marker commemorates a significant clash between American patriots and British forces, offering cultural insights. Located about 9 miles from Buffalo, it provides easy access for those eager to explore the region's heritage.

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Croft State Park

7.0/10 (2 reviews)

Discover the appeal of Croft State Park, a fantastic destination for nature lovers seeking adventure and scenic beauty. Located about 13 miles from Buffalo, this park offers a variety of outdoor experiences amid its picturesque landscapes, making it an ideal spot for relaxation and exploration. Staying nearby allows easy access to its natural charm.

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Walnut Grove Plantation

Perfectly suited for history lovers, Walnut Grove Plantation offers a glimpse into South Carolina’s rich past with its preserved structures and cultural ambiance. Located about 17 miles from Buffalo, this historic site provides an engaging experience, making it a convenient stop for those exploring the area.

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Tyger-10 Nature Park

A must-see for families and culture seekers, Tyger-10 Nature Park offers an immersive nature experience amid beautiful surroundings. Located about 15 miles from Buffalo, this budget-friendly preserve provides a peaceful escape, making it a convenient choice for those looking to explore the natural beauty of South Carolina.

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Top Buffalo Hotel Reviews

Best Western Spartanburg I-26

8/10 Good

"Convenient location right off the interstate with plenty of shops and restaurants in the area. Rooms were very clean with a basic continental breakfast. My only issue was a strong smell of cleaning detergent (Pinesol) throughout. Pool was closed for the season."

Tru by Hilton Spartanburg

10/10 Excellent

"Clean room. Nice gym. Plenty of shopping spots near by along with places to eat. Free breakfast available."

Hampton Inn & Suites Spartanburg-I-26-Westgate Mall

10/10 Excellent

"The front desk staff was exceptionally pleasant. The hotel was clean and smelled amazing. Very comfortable and relaxing. Breakfast was good! Had a great stay and we will be back!"

Comfort Suites Clinton near Presbyterian College

8/10 Good

"Have better carpet,has a smell weird😔"

Comfort Suites At WestGate Mall

10/10 Excellent

"The building as well as the room was clean and inviting. The staff were very friendly and informative. The breakfast was basic but substantial. Eggs both mornings as well as sausage. Make your own waffle like most hotels. Parking was convenient and parking lot was well lit at night for safety. Fitness room was minimal but still allowed for a basic workout."

Hampton Inn & Suites Clinton - I-26

10/10 Excellent

"Very nice!! Would stay again"

Hilton Garden Inn Spartanburg

10/10 Excellent

"There is a restaurant on site and steakhouse across the street. We had great night of sleep!"

Holiday Inn Express Hotel & Suites Spartanburg-North by IHG

10/10 Excellent

"Great staff!"

Fairfield by Marriott Inn & Suites Spartanburg Downtown

10/10 Excellent

"Great breakfast option!"

More cheap stays in Buffalo

Sleep Inn Spartanburg Southwest

501 South Blackstock Rd Spartanburg SC

$74 nightly

$82 total

Nov 1 - Nov 2

Total with taxes and fees

6/10 (651 reviews)

Comfort Suites Clinton near Presbyterian College

12865 Hwy 56 N Clinton SC

$83 nightly

$93 total

Oct 26 - Oct 27

Total with taxes and fees

8/10 Very Good! (815 reviews)

Comfort Suites At WestGate Mall

458 West Blackstock Road Spartanburg SC

$91 nightly

$101 total

Nov 1 - Nov 2

Total with taxes and fees

8.4/10 Very Good! (1,006 reviews)

Best Western Spartanburg I-26

488 South Blackstock Road Spartanburg SC

$97 nightly

$108 total

Oct 18 - Oct 19

Total with taxes and fees

9.2/10 Wonderful! (56 reviews)

Holiday Inn Express Hotel & Suites Spartanburg-North by IHG

161 Sha Ln Spartanburg SC

$105 nightly

$117 total

Nov 1 - Nov 2

Total with taxes and fees

Tru by Hilton Spartanburg

103 Franklin Avenue Spartanburg SC

$106 nightly

$117 total

Nov 1 - Nov 2

Total with taxes and fees

9.2/10 Wonderful! (981 reviews)

Hotels in Buffalo with star-rating

Frequently asked questions

What is the best area to stay in Buffalo?

The best area to stay in Buffalo, South Carolina, is the downtown area, particularly around Main Street, for convenient access to local amenities and a central location.Downtown Buffalo is the commercial and social center of the town. While not a large city, this area offers the most options for dining and shopping within walking distance. Main Street is the primary thoroughfare, connecting various local businesses and community gathering spots.For solo travelers or couples looking for a relaxed stay with easy access to local services, downtown is the ideal choice.

Can I cancel my hotel reservation on Expedia?

You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Buffalo.

How much is the nightly rate at a Buffalo hotel?

Prices for hotels in Buffalo often vary, but you can find a great deal from $65 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate.

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Things to do in Upstate South Carolina

Find hotels in Buffalo, SC from $65

Upfront pricing

Treat yourself

Be picky

Go beyond your typical stay in Buffalo

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for Buffalo hotels

1. The Night Inn

2. Rodeway Inn Union

3. Comfort Suites Clinton near Presbyterian College

4. Days Inn by Wyndham Clinton / Laurens I-26

5. Quality Inn Clinton - Laurens I-26

6. Hampton Inn & Suites Clinton - I-26

7. Best Western Spartanburg I-26

8. Hilton Garden Inn Spartanburg

9. Spartanburg Marriott

10. Tru by Hilton Spartanburg

11. Holiday Inn Express I-26 & Us 29 At Westgate Mall by IHG

12. AC Hotel by Marriott Spartanburg

13. Red Roof Inn Spartanburg - I-85

14. Rodeway Inn Laurens

15. Fairfield by Marriott Inn & Suites Spartanburg Downtown

16. Comfort Suites At WestGate Mall

17. Suburban Studios Spartanburg - I-26

18. Hampton Inn & Suites Spartanburg-I-26-Westgate Mall

19. SUN AND SAND MOTEL

20. ECHO Suites Extended Stay by Wyndham Spartanburg

Where to stay near Buffalo

Union

Monarch Mill

Jonesville

Pauline

Cross Anchor

Stay near popular attractions around Buffalo

Musgrove Mill State Historic Site

Veterans Memorial Park

Union County Museum

Rose Hill Plantation State Historic Site

Battle of Blackstock Marker

Croft State Park

Walnut Grove Plantation

Tyger-10 Nature Park

Top Buffalo Hotel Reviews

Best Western Spartanburg I-26

Tru by Hilton Spartanburg

Hampton Inn & Suites Spartanburg-I-26-Westgate Mall

Comfort Suites Clinton near Presbyterian College

Comfort Suites At WestGate Mall

Hampton Inn & Suites Clinton - I-26

Hilton Garden Inn Spartanburg

Holiday Inn Express Hotel & Suites Spartanburg-North by IHG

Fairfield by Marriott Inn & Suites Spartanburg Downtown

More cheap stays in Buffalo

Sleep Inn Spartanburg Southwest

Comfort Suites Clinton near Presbyterian College

Comfort Suites At WestGate Mall

Best Western Spartanburg I-26

Holiday Inn Express Hotel & Suites Spartanburg-North by IHG

Tru by Hilton Spartanburg

Hotels in Buffalo with star-rating

Frequently asked questions

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