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Our top choices for Buffalo hotels

A modern hotel lobby with a coffee station, seating area, and a large screen.
A reception area with a brick counter, a framed certificate on the wall, and a sign indicating hotel ownership.
A breakfast bar with a microwave, toaster, and clear plastic containers. There are framed pictures on the wall and a refrigerator.
A hotel room with two beds, each with a headboard and a lamp.

1. Quality Inn Union US Hwy 176

Quality Inn Union US Hwy 176
Union
United States
Mary
$67 nightly
$75 total
Sep 27 - Sep 28
Total with taxes and fees
Quality Inn Union US Hwy 176
A hotel room with a bed, a sofa, a nightstand, and a small table.
A reception area with a blue wall, a wooden counter, a glass door leading outside, and a potted plant.
A row of residential buildings with a blue door, a white window, and a vent on the wall.
A rectangular pool with a blue border, surrounded by a black fence. There are lounge chairs and a small table with chairs along the poolside.

2. Rodeway Inn Union

Rodeway Inn Union
Union
United States
Keith
$61 nightly
$67 total
Sep 23 - Sep 24
Total with taxes and fees
Rodeway Inn Union
A hotel room with two beds, a desk, a chair, a TV, and a window with curtains.
A reception area with a counter, seating, a clock, and a sign for 'The Night'.
A building with a sign for "The Night Inn" featuring a stylized 'N' logo.
A motel with a single-story structure, a covered parking area, and a well-maintained lawn.

3. The Night Inn

The Night Inn
Union
United States
Charles
$69 nightly
$75 total
Sep 26 - Sep 27
Total with taxes and fees
The Night Inn
A hotel with a central entrance, multiple floors, and a flag display.
A hotel room with a bed, a sofa, a coffee table, two lamps, a framed picture, and a mirror.
A hotel reception area with a modern reception desk, seating area, and large windows.
A breakfast buffet with various food items, coffee machines, and a toaster.

4. Comfort Suites Clinton near Presbyterian College

Comfort Suites Clinton near Presbyterian College
Clinton
United States
Jason
$98 nightly
$110 total
Sep 20 - Sep 21
Total with taxes and fees
Comfort Suites Clinton near Presbyterian College
A modern indoor space with a sofa, tables, chairs, and a pool view.
A modern interior with a stone fireplace, wooden tables and chairs, and a large orange sofa.
A Hampton Inn & Suites hotel with a modern facade, a welcoming entrance, and a flagpole.
A gym with treadmills, weight machines, and a mirror reflecting the equipment.

5. Hampton Inn & Suites Clinton - I-26

Hampton Inn & Suites Clinton - I-26
Clinton
United States
Kendra
$110 nightly
$123 total
Sep 6 - Sep 7
Total with taxes and fees
Hampton Inn & Suites Clinton - I-26
A modern living room with a sofa, armchairs, a patterned rug, and a Buddha statue.
A swimming pool with a lifeguard chair, a shallow water sign, and a no diving allowed sign.
A laundry room with a washing machine, dryer, chair, and table.
A conference room with tables and chairs, a television, and a whiteboard.

6. Days Inn by Wyndham Clinton / Laurens I-26

Days Inn by Wyndham Clinton / Laurens I-26
Clinton
United States
Daniel
$61 nightly
$69 total
Aug 31 - Sep 1
Total with taxes and fees
Days Inn by Wyndham Clinton / Laurens I-26
A modern lobby with a reception desk, seating area, and a television screen.
A swimming pool with lounge chairs and tables, surrounded by brick buildings and a covered seating area.
A hotel room with two beds, a desk with a lamp, a chair, a patterned rug, and a large window.
A modern restaurant with high tables and chairs, a counter with a coffee machine, and a patterned wall.

7. Best Western Spartanburg I-26

Best Western Spartanburg I-26
Spartanburg
United States
Jonathan
$93 nightly
$103 total
Sep 6 - Sep 7
Total with taxes and fees
Best Western Spartanburg I-26
A hotel lobby with a curved outdoor seating area, a fire pit, and a pool.
A lobby with a stone fireplace, sofas, a TV mounted on the wall, and a bar area in the background.
A grand hotel lobby with a marble staircase, ornate carpet, and large landscape paintings on the walls.
A spacious lobby with a high ceiling, chandeliers, a registration desk, and potted plants.

8. Spartanburg Marriott

Spartanburg Marriott
Spartanburg
Canada
Sarah
$118 nightly
$131 total
Sep 13 - Sep 14
Total with taxes and fees
Spartanburg Marriott
A hotel room with a bed, a desk with a computer, a television, and a microwave.
A room with two beds, each with a wooden headboard and a floral bedspread. There is a small wooden table beside the beds.
A bedroom with a bed, wooden headboard, bedside tables, and a ceiling light.
A bathroom with a bathtub, shower curtain, and marble wall tiles.

9. SUN AND SAND MOTEL

SUN AND SAND MOTEL
Spartanburg
United States
Jeffrey
$47 nightly
$52 total
Sep 2 - Sep 3
Total with taxes and fees
SUN AND SAND MOTEL
A rooftop bar with seating, a bar area, and a view of the cityscape at dusk.
A spacious living area with a modern sofa, armchairs, a coffee table, and a dining area with chairs and a table.
A modern restaurant with a bar area, high ceilings, and a view of the cityscape.
A swimming pool with steps leading up to a building entrance, surrounded by lounge chairs and umbrellas.

10. AC Hotel by Marriott Spartanburg

AC Hotel by Marriott Spartanburg
Spartanburg
United States
shannon
$149 nightly
$165 total
Sep 6 - Sep 7
Total with taxes and fees
AC Hotel by Marriott Spartanburg

11. Quality Inn Clinton - Laurens I-26

Quality Inn Clinton - Laurens I-26
Clinton
United States
Tyiesha
$82 nightly
$92 total
Sep 25 - Sep 26
Total with taxes and fees
Quality Inn Clinton - Laurens I-26
A hotel room with a bed, a blue sofa, a wooden coffee table, a desk with a chair, and a framed abstract painting on the wall.
A Holiday Inn Express & Suites hotel with a covered entrance and multiple stories.
A large indoor swimming pool with a diving board, multiple doors, and seating areas.
A hotel reception area with a modern design, featuring a reception desk, two seating areas with chairs, and a wall-mounted artwork.

12. Holiday Inn Express Hotel & Suites Spartanburg-North by IHG

Holiday Inn Express Hotel & Suites Spartanburg-North by IHG
Spartanburg
United States
Michael
$99 nightly
$110 total
Sep 20 - Sep 21
Total with taxes and fees
Holiday Inn Express Hotel & Suites Spartanburg-North by IHG
An outdoor seating area with sofas, a fire pit, and string lights.
A modern hotel with a multi-story structure, large windows, and a prominent vertical light strip.
A modern interior with hanging chairs, tables, and a view of the parking lot.
A self-service kiosk with a variety of snacks and beverages, a microwave, and a refrigerated display.

13. Tru by Hilton Spartanburg

Tru by Hilton Spartanburg
Spartanburg
United States
Jeremy
$99 nightly
$110 total
Sep 20 - Sep 21
Total with taxes and fees
Tru by Hilton Spartanburg
A modern kitchen with a central island, equipped with a microwave, toaster, and coffee machine.
A gym with treadmills, elliptical machines, and weight machines.
A hotel room with a desk, office chair, sofa, and a large wall art piece.
A modern lobby with blue sofas, a reception desk, and a glass coffee table.

14. Comfort Suites At WestGate Mall

Comfort Suites At WestGate Mall
Spartanburg
United States
Brittney
$89 nightly
$99 total
Sep 20 - Sep 21
Total with taxes and fees
Comfort Suites At WestGate Mall
A conference room with a long table, blue and orange chairs, and a reception desk in the background.
A coffee station with labeled dispensers for hot water, decaf roast, light roast, and dark roast coffee.
A Hampton Inn hotel with a clear entrance, well-maintained lawn, and a flagpole.
A conference room with two desks, two chairs, and a small table.

15. Hampton Inn Spartanburg-North I-85

Hampton Inn Spartanburg-North I-85
Spartanburg
United States
Stephanie
$106 nightly
$117 total
Sep 9 - Sep 10
Total with taxes and fees
Hampton Inn Spartanburg-North I-85
A dining area with tables and chairs, a television mounted on the wall, and a kitchen area with appliances.
A hotel room with a bed, a desk with a computer, a chair, a lamp, and a view of the outdoors through a window.
A Rodeway Inn with a two-story building, a parking lot, and a few cars parked in front.
A hotel lobby with a reception desk, seating area, and a television.

16. Rodeway Inn Laurens

Rodeway Inn Laurens
Laurens
United States
Jason
$65 nightly
$73 total
Sep 29 - Sep 30
Total with taxes and fees
Rodeway Inn Laurens
A modern living room with a stone accent wall, a flat-screen TV, and a blue abstract rug.
A modern lobby with a sofa, armchairs, and a coffee table. There is a reception desk and a dining area in the background.
A modern hotel with a prominent Fairfield sign, multiple floors, and a well-lit entrance.
A modern dining area with wooden flooring, round tables, and chairs. There are wall-mounted artworks and a sign that reads "LESS MONDAY MORE SUMMER".

17. Fairfield by Marriott Inn & Suites Spartanburg Downtown

Fairfield by Marriott Inn & Suites Spartanburg Downtown
Spartanburg
United States
Demiko
$121 nightly
$134 total
Sep 13 - Sep 14
Total with taxes and fees
Fairfield by Marriott Inn & Suites Spartanburg Downtown
A modern breakfast area with a blue-tiled backsplash, a coffee station, and seating with teal cushions.
A modern living room with a stone wall, a flat-screen TV, a sofa, a coffee table, and a fireplace.
A reception area with a modern design, featuring a stone wall, two reception desks, and a potted plant.
A hotel room with a large bed, a desk with a chair, a television, and a window with curtains.

18. Sleep Inn Spartanburg Southwest

Sleep Inn Spartanburg Southwest
Spartanburg
United States
CYNTHIA
$71 nightly
$79 total
Sep 6 - Sep 7
Total with taxes and fees
Sleep Inn Spartanburg Southwest
A bar area with a long counter, multiple stools, and shelves stocked with bottles.
A restaurant with a central island seating area, multiple tables, and a large mural on the wall.
A spacious lobby with a bar area, seating, and large windows.
A hotel entrance with a covered walkway, a landscaped area with trees, and a well-lit building facade.

19. Hilton Garden Inn Spartanburg

Hilton Garden Inn Spartanburg
Spartanburg
United States
Stan
$118 nightly
$131 total
Sep 6 - Sep 7
Total with taxes and fees
Hilton Garden Inn Spartanburg
An outdoor patio with a fire pit, wicker furniture, and a stone wall.
A modern lounge area with a sofa, chairs, and tables, featuring a glass partition, pendant lights, and artwork on the walls.
A hotel with a swimming pool, multiple floors, and outdoor seating areas.
A spacious living area with a fireplace, comfortable seating, and a large TV.

20. Residence Inn by Marriott Spartanburg Westgate

Residence Inn by Marriott Spartanburg Westgate
Spartanburg
United States
Shirleen
$142 nightly
$157 total
Sep 6 - Sep 7
Total with taxes and fees
Residence Inn by Marriott Spartanburg Westgate
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Where to stay near Buffalo

Buffalo offers a charming blend of outdoor adventures and scenic beauty. Explore lush parks, enjoy romantic lakeside strolls, or indulge in wellness retreats. Nearby towns provide a friendly atmosphere, perfect for family outings and cultural experiences, making it an ideal getaway for relaxation and rejuvenation.
A neoclassical courthouse with a dome and columns, a flagpole, and a parked car in front.
A large brick building with white columns and a central entrance.
A large tree with moss-covered branches and a floral wreath at its base.
A set of stone steps leading to a gated entrance with a wrought iron gate.
Photo by Laurie Craven

Union

For travelers seeking a blend of nature and history, Union is the perfect base to explore the charm of South Carolina. This welcoming city offers access to the scenic Rose Hill Plantation State Historic Site, the tranquil Veterans Memorial Park, and the engaging Union County Museum, ensuring a rich experience for families and nature enthusiasts alike. Located about 4 miles from Buffalo, Union provides a smart choice for those looking to immerse themselves in local culture while enjoying outdoor activities.

Monarch Mill

Plan your stay in Monarch Mill, a great choice for travelers seeking a blend of business, family, and outdoor adventures. This charming village is near attractions like Veterans Memorial Park, perfect for relaxation, and the Union County Museum, where history comes alive. For a taste of local heritage, don’t miss the Rose Hill Plantation State Historic Site. Located about 6 miles from Buffalo, Monarch Mill is an ideal spot for a memorable getaway.

Jonesville

If you are a family or nature enthusiast, look no further than Jonesville, a charming city known for its inviting parks and recreational activities. Enjoy the serene landscapes at Croft State Park or unwind at the urban charm of Veterans Memorial Park, both perfect for outdoor adventures. With easy access to local shopping and golf courses, you’ll find plenty to explore. Located about 8 miles from Buffalo, Jonesville is an ideal choice for a delightful stay.

Pauline

Immerse yourself in Pauline, where travelers with a penchant for family outings and nature adventures can easily access scenic spots and recreational activities. Enjoy the rich history at Walnut Grove Plantation, explore the natural beauty of Croft State Park, and unwind at Tyger-10 Nature Park. With its charm and variety, Pauline serves as a delightful base for your exploration of the surrounding area. Located about 10 miles from Buffalo, it’s a smart choice for your next getaway.

Cross Anchor

Travelers looking for a charming getaway will find Cross Anchor to be the ideal base for their vacation, featuring a blend of family-friendly activities and beautiful natural scenery. This welcoming city is perfect for those seeking outdoor adventures and romantic escapes, with highlights like the Musgrove Mill State Historic Site and the nearby lake for leisurely days. With Cross Anchor just about 11 miles from Buffalo, it offers a smart choice for a budget-friendly stay while enjoying local attractions and experiences.

Stay near popular attractions around Buffalo

Buffalo, South Carolina, offers a delightful blend of outdoor adventures and romantic scenery. Explore the charming urban parks, historic houses, and a welcoming library. Whether you're seeking family fun or a serene city experience, Buffalo is the perfect base for unforgettable memories and exploration.

Musgrove Mill State Historic Site

8.6/10 (19 reviews)
A fascinating mix of history and nature awaits outdoor enthusiasts at Musgrove Mill State Historic Site. This National Park features scenic landscapes and opportunities for adventure, showcasing the site’s rich Revolutionary War heritage. Located about 13 miles from Buffalo, it’s a convenient stop for a memorable day trip.
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Veterans Memorial Park

9.0/10 (11 reviews)
Set the stage for your family getaway at Veterans Memorial Park, an inviting urban park in Union, South Carolina. Embrace the outdoors with its vibrant atmosphere, perfect for picnics and leisurely strolls. Located about 4 miles from Buffalo, this park offers easy access, making it a convenient stop for your vacation adventures.
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Union County Museum

7.6/10 (8 reviews)
Ideal for history buffs, Union County Museum offers a rich glimpse into the local culture and heritage of Union, South Carolina. Located about 3 miles from Buffalo, this museum showcases fascinating exhibits that tell the story of the region. Staying nearby allows easy access to this cultural gem.
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Rose Hill Plantation State Historic Site

8.8/10 (6 reviews)
Ideal for travelers interested in history and culture, Rose Hill Plantation State Historic Site offers a glimpse into South Carolina's rich past. Located about 8 miles from Buffalo, visitors can explore its beautifully preserved grounds and learn about plantation life, making it a convenient and enriching stop on your journey.
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Battle of Blackstock Marker

8.0/10 (2 reviews)
Visitors often appreciate how this spot delivers a glimpse into the rich history of the Revolutionary War. The Battle of Blackstock marker commemorates a significant clash between American patriots and British forces, offering cultural insights. Located about 9 miles from Buffalo, it provides easy access for those eager to explore the region's heritage.
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Croft State Park

7.0/10 (2 reviews)
Discover the appeal of Croft State Park, a fantastic destination for nature lovers seeking adventure and scenic beauty. Located about 13 miles from Buffalo, this park offers a variety of outdoor experiences amid its picturesque landscapes, making it an ideal spot for relaxation and exploration. Staying nearby allows easy access to its natural charm.
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Walnut Grove Plantation

Perfectly suited for history lovers, Walnut Grove Plantation offers a glimpse into South Carolina’s rich past with its preserved structures and cultural ambiance. Located about 17 miles from Buffalo, this historic site provides an engaging experience, making it a convenient stop for those exploring the area.
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Tyger-10 Nature Park

A must-see for families and culture seekers, Tyger-10 Nature Park offers an immersive nature experience amid beautiful surroundings. Located about 15 miles from Buffalo, this budget-friendly preserve provides a peaceful escape, making it a convenient choice for those looking to explore the natural beauty of South Carolina.
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Top Buffalo Hotel Reviews

Hampton Inn & Suites Clinton - I-26

Hampton Inn & Suites Clinton - I-26

10/10 Excellent
"Very nice experience. Would highly recommend."
Christin 2-night trip
Posted 17 hours ago
Hampton Inn & Suites Clinton - I-26
Comfort Suites At WestGate Mall

Comfort Suites At WestGate Mall

8/10 Good
"None"
Edison 2-night trip
Posted 2 days ago
Comfort Suites At WestGate Mall
Tru by Hilton Spartanburg

Tru by Hilton Spartanburg

10/10 Excellent
"Robert was so helpful! What a great representative of the property. Clean, spacious, convenient!"
Wendy 1-night trip
Posted 2 days ago
Tru by Hilton Spartanburg
Holiday Inn Express I-26 & Us 29 At Westgate Mall by IHG

Holiday Inn Express I-26 & Us 29 At Westgate Mall by IHG

10/10 Excellent
"From the moment we checked in everyone was so helpful. The room was spotless along with hallways and stairwells. Breakfast was delicious and freshSaturday and Sunday morning."
Tracie 1-night trip
Posted 3 days ago
Holiday Inn Express I-26 & Us 29 At Westgate Mall by IHG
Hilton Garden Inn Spartanburg

Hilton Garden Inn Spartanburg

10/10 Excellent
"Room and other facilities were clean and staff was nice. Not a lot of bells and whistles, but it got the job done well."
Matthew 2-night trip
Posted 5 days ago
Hilton Garden Inn Spartanburg
Spartanburg Marriott

Spartanburg Marriott

10/10 Excellent
"I had a nice stay for a week, and the staff were all great, the food in the restaurant was great. Nice cozy happy hour bar scene. I definitely recommend."
Janette 9-night trip
Posted 5 days ago
Spartanburg Marriott
Hampton Inn Spartanburg-North I-85

Hampton Inn Spartanburg-North I-85

10/10 Excellent
"We were surprised at the look from the outside, but it seems there was maintenance taking place. The stay was comfortable."
Amy 2-night trip
Posted 6 days ago
Hampton Inn Spartanburg-North I-85
Best Western Spartanburg I-26

Best Western Spartanburg I-26

10/10 Excellent
"Property was clean and room was clean. Bed was super comfortable and staff was amazing"
Jonathan 1-night trip
Posted 6 days ago
Best Western Spartanburg I-26
Hampton Inn & Suites Spartanburg-I-26-Westgate Mall

Hampton Inn & Suites Spartanburg-I-26-Westgate Mall

10/10 Excellent
"Great stay! Close to restaurants, comfortable bed."
Carolyn 1-night trip
Posted 7 days ago
Hampton Inn & Suites Spartanburg-I-26-Westgate Mall

More cheap stays in Buffalo

Days Inn by Wyndham Clinton / Laurens I-26

Days Inn by Wyndham Clinton / Laurens I-26

12374 Highway 56 N Clinton SC
$61 nightly
$69 total
Aug 31 - Sep 1
Total with taxes and fees
Days Inn by Wyndham Clinton / Laurens I-26
Sleep Inn Spartanburg Southwest

Sleep Inn Spartanburg Southwest

501 South Blackstock Rd Spartanburg SC
$71 nightly
$79 total
Sep 6 - Sep 7
Total with taxes and fees
Sleep Inn Spartanburg Southwest
Comfort Suites At WestGate Mall

Comfort Suites At WestGate Mall

458 West Blackstock Road Spartanburg SC
$89 nightly
$99 total
Sep 20 - Sep 21
Total with taxes and fees
8.4/10 Very Good! (1,003 reviews)
Comfort Suites At WestGate Mall
Tru by Hilton Spartanburg

Tru by Hilton Spartanburg

103 Franklin Avenue Spartanburg SC
$99 nightly
$110 total
Sep 20 - Sep 21
Total with taxes and fees
9.2/10 Wonderful! (959 reviews)
Tru by Hilton Spartanburg
Holiday Inn Express Hotel & Suites Spartanburg-North by IHG

Holiday Inn Express Hotel & Suites Spartanburg-North by IHG

161 Sha Ln Spartanburg SC
$99 nightly
$110 total
Sep 20 - Sep 21
Total with taxes and fees
8.6/10 Excellent! (1,001 reviews)
Holiday Inn Express Hotel & Suites Spartanburg-North by IHG
Comfort Suites Clinton near Presbyterian College

Comfort Suites Clinton near Presbyterian College

12865 Hwy 56 N Clinton SC
$98 nightly
$110 total
Sep 20 - Sep 21
Total with taxes and fees
8/10 Very Good! (805 reviews)
Comfort Suites Clinton near Presbyterian College

Hotels in Buffalo with star-rating

Frequently asked questions

What is the best area to stay in Buffalo?
The best area to stay in Buffalo, South Carolina, is the downtown area, particularly around Main Street, for convenient access to local amenities and a central location.Downtown Buffalo is the commercial and social center of the town. While not a large city, this area offers the most options for dining and shopping within walking distance. Main Street is the primary thoroughfare, connecting various local businesses and community gathering spots.For solo travelers or couples looking for a relaxed stay with easy access to local services, downtown is the ideal choice.
Can I cancel my hotel reservation on Expedia?
You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Buffalo.
How much is the nightly rate at a Buffalo hotel?
Prices for hotels in Buffalo often vary, but you can find a great deal from $52 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate.

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