Desoto Lakes Vacations from $448

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Your Desoto Lakes Vacation

Book a Desoto Lakes vacation package and experience the rhythm and lifestyle of this unique neighborhood. With all your travel plans taken care of, the only thing you need to worry about here is living your best life. Not sure where to go during your trip to Desoto Lakes? Nearby attractions like Mall at University Town Center, Nathan Benderson Park and Ed Smith Stadium are good places to start. Stop dreaming and start doing. When you're ready to book your dream vacation to Desoto Lakes, Expedia is here to help.

The Latest Desoto Lakes Vacation Packages

Price found within the past 48 hours. Click for updated prices.
voco Sarasota by IHG

voco Sarasota by IHG

3.5 out of 5
Central Sarasota
Save 100% on your flight
per person
Aug 16 - Aug 23
found 1 day ago
Roundtrip flight included
Boston (BOS) to Tampa (TPA)
9.2/10 Wonderful! (1,008 reviews)
I was impressed with the room really clean. Happy with this choice. And thank you team Expedia

Reviewed on Jul 13, 2025

Ocean Club Treasure Island Hotel

Ocean Club Treasure Island Hotel

4 out of 5
Save 100% on your flight
per person
Sep 15 - Sep 22
found 1 day ago
Roundtrip flight included
Boston (BOS) to Tampa (TPA)
9.6/10 Exceptional! (518 reviews)
No Complaints ...very clean, friendly staff. Very close to beach

Reviewed on Jul 15, 2025

Coral Reef Beach Resort

Coral Reef Beach Resort

3.5 out of 5
Save 100% on your flight
per person
Oct 1 - Oct 8
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Tampa (TPA)
8.8/10 Excellent! (251 reviews)
Wyndham Grand Clearwater Beach

Wyndham Grand Clearwater Beach

4 out of 5
Save 100% on your flight
per person
Sep 19 - Sep 26
found 1 day ago
Roundtrip flight included
Boston (BOS) to Tampa (TPA)
9.4/10 Exceptional! (2,352 reviews)
Staff was amazing the room was ok it better online. Overall experience was good

Reviewed on Jul 14, 2025

Barsala At The Wayland Condos

Barsala At The Wayland Condos

4 out of 5
Save 100% on your flight
per person
Aug 19 - Aug 26
found 1 day ago
Roundtrip flight included
Boston (BOS) to Tampa (TPA)
7.6/10 Good! (10 reviews)
My little getaway was amazing!!! The studio was beautiful, had everything we needed I wasn't expecting a full kitchen with baking utensils as well. We had a blast the view was incredible. I loved the outside setup near the pool as well. Will definitely be booking another getaway real soon!!

Reviewed on Jun 10, 2025

Where to stay in Desoto Lakes

Find the best Desoto Lakes areas and neighborhoods for the activities you enjoy most. Learn more about Desoto Lakes
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South Sarasota

While visiting South Sarasota, you might make a stop by sights like The Landings and Coconuts Family Entertainment Center.

Find hotels in South Sarasota

Desoto Lakes Hotel Deals

Kompose Boutique Hotel
Kompose Boutique Hotel
3 out of 5
965 University Pkwy, Sarasota, FL
Fully refundableReserve now, pay when you stay
$85 nightly
The price is $96 total per night from Aug 3 to Aug 4
$96 total
Aug 3 - Aug 4
Total includes taxes and fees
9/10 Wonderful! (4,132 reviews)
"Great staff, location and property."

Reviewed on Jul 13, 2025

Kompose Boutique Hotel
Tropical Beach Resorts
Tropical Beach Resorts
3.5 out of 5
6717 Sara Sea Circle, Siesta Key, FL
Fully refundableReserve now, pay when you stay
$206 nightly
The price is $233 total per night from Aug 3 to Aug 4
$233 total
Aug 3 - Aug 4
Total includes taxes and fees
9.2/10 Wonderful! (4,756 reviews)
"Beautiful! Amazing!"

Reviewed on Jul 11, 2025

Tropical Beach Resorts
Compass Hotel by Margaritaville Anna Maria Sound
Compass Hotel by Margaritaville Anna Maria Sound
4 out of 5
12324 Manatee Avenue West, Bradenton, FL
Fully refundableReserve now, pay when you stay
$197 nightly
The price is $223 total per night from Jul 22 to Jul 23
$223 total
Jul 22 - Jul 23
Total includes taxes and fees
9.4/10 Exceptional! (1,555 reviews)
"Amazing hotel"

Reviewed on Jul 12, 2025

Compass Hotel by Margaritaville Anna Maria Sound
See all 13,718 properties in Desoto Lakes
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

All Inclusive Vacations

All Inclusive Vacations

Beach Vacations

Beach Vacations

Kid Friendly Vacations

Kid Friendly Vacations

Discover the most popular places to visit in Desoto Lakes

Lido Beach showing general coastal views and a sandy beach

Lido Beach

4.5/5(1,225 reviews)

Visit a beach not far from an upscale shopping area. The warm waters are as inviting as the white sand.

Lido Beach
St. Armands Circle featuring a statue or sculpture

St. Armands Circle

4.5/5(1,234 reviews)

Consider this area as a circular outdoor mall. Like any mall, you can shop, dine, browse or just people-watch. Unlike most malls, this one never closes to walkers.

St. Armands Circle
Mall at University Town Center

Mall at University Town Center

4.5/5(363 reviews)

You can search for that perfect souvenir at Mall at University Town Center during your visit to Sarasota. Attend a sporting event or discover the beautiful sunsets in this family-friendly area.

Mall at University Town Center

Things to do

HydroCats

HydroCats - 2 Hour CraigCat Sightseeing Tour

$146
per adult
100% of travellers recommend
HydroCats - 2 Hour CraigCat Sightseeing Tour
Naples Florida: Downtown Electric Moped Tour

Naples Florida: Downtown Electric Moped Tour

$60
per adult
100% of travellers recommend
Naples Florida: Downtown Electric Moped Tour
Siesta Key, FL - Clear Kayak LED Night Glass Bottom Tour

Siesta Key, FL - Clear Kayak LED Night Glass Bottom Tour

$65
per adult
Siesta Key, FL - Clear Kayak LED Night Glass Bottom Tour
See all activities in Sarasota
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.