Desoto Lakes Vacations from $423

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Your Desoto Lakes Vacation

Book a Desoto Lakes vacation package and experience the rhythm and lifestyle of this unique neighborhood. With all your travel plans taken care of, the only thing you need to worry about here is living your best life. Not sure where to go during your trip to Desoto Lakes? Nearby attractions like Mall at University Town Center, Nathan Benderson Park and Ed Smith Stadium are good places to start. Stop dreaming and start doing. When you're ready to book your dream vacation to Desoto Lakes, Expedia is here to help.

The Latest Desoto Lakes Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Mar Bay Motel &Suites

Mar Bay Motel &Suites

2 out of 5
Save 100% on your flight
Price was $760, price is now $423 per person
$423
per person
Apr 19 - Apr 24
found 20 hours ago
Roundtrip non-stop flight included
New York (NYC) to Tampa (TPA)
8.6/10 Excellent! (60 reviews)
Older property but very well maintained. It was clean and had everything we needed for our stay. Great communication with the host.

Reviewed on Feb 10, 2026

Seaside at Anna Maria Island Inn

Seaside at Anna Maria Island Inn

2.5 out of 5
Save 100% on your flight
Price was $2,290, price is now $1,394 per person
$1,394
per person
Apr 17 - Apr 20
found 1 day ago
Roundtrip flight included
Boston (BOS) to Sarasota (SRQ)
9.6/10 Exceptional! (45 reviews)
Beachfront location!

Reviewed on Feb 10, 2026

The Residences at Siesta Key Beach by Hyatt Vacation Club

The Residences at Siesta Key Beach by Hyatt Vacation Club

3.5 out of 5
South Village
Save 100% on your flight
Price was $2,984, price is now $1,821 per person
$1,821
per person
Apr 20 - Apr 24
found 1 day ago
Roundtrip flight included
Boston (BOS) to Sarasota (SRQ)
9.6/10 Exceptional! (294 reviews)
The view was fantastic and staff went out of their way to make your visit enjoyable!

Reviewed on Feb 3, 2026

FUSION Resort Waterfront Suites

FUSION Resort Waterfront Suites

3.5 out of 5
Save 100% on your flight
Price was $2,030, price is now $1,328 per person
$1,328
per person
Apr 18 - Apr 24
found 1 day ago
Roundtrip flight included
Boston (BOS) to Tampa (TPA)
9.2/10 Wonderful! (1,097 reviews)
Very clean and yes I would come again

Reviewed on Feb 13, 2026

Provident Oceana Beachfront Suites

Provident Oceana Beachfront Suites

3.5 out of 5
Save 100% on your flight
Price was $2,361, price is now $1,569 per person
$1,569
per person
Apr 4 - Apr 10
found 1 day ago
Roundtrip flight included
Boston (BOS) to Tampa (TPA)
9.4/10 Exceptional! (606 reviews)
Room was very clean, but the dishwasher didn't clean the dishes. the staff was very helpful and friendly.

Reviewed on Feb 6, 2026

Where to stay in Desoto Lakes

Find the best Desoto Lakes areas and neighborhoods for the activities you enjoy most. Learn more about Desoto Lakes
Sarasota, Florida, USA Downtown Skyline

South Sarasota

While visiting South Sarasota, you might make a stop by sights like The Landings and Coconuts Family Entertainment Center.

Find hotels in South Sarasota

Desoto Lakes Hotel Deals

Kompose Boutique Hotel

Kompose Boutique Hotel

3 out of 5
965 University Pkwy Sarasota FL
Fully refundableReserve now, pay when you stay
$182 nightly
The price is $205 total per night from Feb 16 to Feb 17
$205 total
Feb 16 - Feb 17
Total with taxes and fees
9/10 Wonderful! (4,981 reviews)
Staff was great…room was spotless. Breakfast was great.

Reviewed on Feb 12, 2026

Kompose Boutique Hotel
Golden Host Resort - Sarasota

Golden Host Resort - Sarasota

3 out of 5
4675 N Tamiami Trl Sarasota FL
Fully refundable
$110 nightly
The price is $125 total per night from Feb 17 to Feb 18
$125 total
Feb 17 - Feb 18
Total with taxes and fees
8.4/10 Very Good! (2,268 reviews)
Nice staff

Reviewed on Feb 10, 2026

Golden Host Resort - Sarasota
Tropical Beach Resorts

Tropical Beach Resorts

3.5 out of 5
6717 Sara Sea Circle Siesta Key FL
Fully refundableReserve now, pay when you stay
$349 nightly
The price is $395 total per night from Feb 18 to Feb 19
$395 total
Feb 18 - Feb 19
Total with taxes and fees
9.2/10 Wonderful! (5,290 reviews)
It was perfect location it was beautiful clean hotel I would definitely at least stay there again

Reviewed on Feb 10, 2026

Tropical Beach Resorts
See all 14,510 properties in Desoto Lakes
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Vacations
All Inclusive Vacations
Beach Vacations
Beach Vacations
Kid Friendly Vacations
Kid Friendly Vacations

Discover the most popular places to visit in Desoto Lakes

Lido Beach showing general coastal views and a sandy beach

Lido Beach

Visit a beach not far from an upscale shopping area. The warm waters are as inviting as the white sand.

Lido Beach
EJETFA The official entrance at the new Mall at University Town Center located just off I-75 on University Parkway in Sarasota Floria

Mall at University Town Center

You can search for that perfect souvenir at Mall at University Town Center during your visit to Sarasota. Attend a sporting event or discover the beautiful sunsets in this family-friendly area.

Mall at University Town Center
St. Armands Circle featuring a statue or sculpture

St. Armands Circle

Consider this area as a circular outdoor mall. Like any mall, you can shop, dine, browse or just people-watch. Unlike most malls, this one never closes to walkers.

St. Armands Circle

Things to do

Kayak Tour through Mangrove Tunnels

Mangroves, Manatees, and a Hidden Beach: Kayak Tour

$59
per adult
94% of travellers recommend
Mangroves, Manatees, and a Hidden Beach: Kayak Tour
Sarasota - Clear Kayak LED Night Glass Bottom Tour

Sarasota - Clear Kayak LED Night Glass Bottom Tour

$65
per adult
80% of travellers recommend
Sarasota - Clear Kayak LED Night Glass Bottom Tour
Picture 4 for Activity Bradenton: Anna Maria Island Guided Kayaking Manatee Tour

Bradenton: Anna Maria Island Guided Kayaking Manatee Tour

$55
per adult
100% of travellers recommend
Bradenton: Anna Maria Island Guided Kayaking Manatee Tour
See all activities in Sarasota
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.