Desoto Lakes Vacations from $461

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Your Desoto Lakes Vacation

Book a Desoto Lakes vacation package and experience the rhythm and lifestyle of this unique neighborhood. With all your travel plans taken care of, the only thing you need to worry about here is living your best life. Not sure where to go during your trip to Desoto Lakes? Nearby attractions like Mall at University Town Center, Nathan Benderson Park and Ed Smith Stadium are good places to start. Stop dreaming and start doing. When you're ready to book your dream vacation to Desoto Lakes, Expedia is here to help.

The Latest Desoto Lakes Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Saddlebrook Resort

Saddlebrook Resort

4 out of 5
Wesley Chapel South
Price was $1,069, price is now $461 per person
$461
per person
Jan 27 - Feb 1
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to Tampa (TPA)
No reviews
Delray House With Hot tub & Game Room

Delray House With Hot tub & Game Room

3.5 out of 5
Palm River-Clair Mel
Save 100% on your flight
Price was $1,018, price is now $489 per person
$489
per person
Jan 28 - Feb 2
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to Sarasota (SRQ)
2/10 (2 reviews)
Family Home Tampa

Family Home Tampa

2 out of 5
Forest Hills
Price was $1,153, price is now $563 per person
$563
per person
Mar 9 - Mar 14
found 14 hours ago
Roundtrip flight included
Philadelphia (PHL) to Sarasota (SRQ)
7.6/10 Good! (4 reviews)
The Residences at Siesta Key Beach by Hyatt Vacation Club

The Residences at Siesta Key Beach by Hyatt Vacation Club

3.5 out of 5
South Village
Save 100% on your flight
Price was $2,435, price is now $1,392 per person
$1,392
per person
Mar 9 - Mar 13
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to Sarasota (SRQ)
9.6/10 Exceptional! (294 reviews)
The unit was gorgeous and so was the property. Everything exceeded our expectations.

Reviewed on Dec 26, 2025

Plaza Beach Hotel Beachfront Resort

Plaza Beach Hotel Beachfront Resort

3 out of 5
Save 100% on your flight
Price was $2,839, price is now $1,667 per person
$1,667
per person
Mar 1 - Mar 7
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to Tampa (TPA)
9/10 Wonderful! (1,000 reviews)
Best place on earth right on the Beach , quite relaxing and the staff is wonderful.Definitely be back .

Reviewed on Dec 22, 2025

Where to stay in Desoto Lakes

Find the best Desoto Lakes areas and neighborhoods for the activities you enjoy most. Learn more about Desoto Lakes
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South Sarasota

While visiting South Sarasota, you might make a stop by sights like The Landings and Coconuts Family Entertainment Center.

Find hotels in South Sarasota

Desoto Lakes Hotel Deals

Kompose Boutique Hotel

Kompose Boutique Hotel

3 out of 5
965 University Pkwy Sarasota FL
Fully refundableReserve now, pay when you stay
$116 nightly
The price is $131 total per night from Dec 27 to Dec 28
$131 total
Dec 27 - Dec 28
Total with taxes and fees
9/10 Wonderful! (4,800 reviews)
Breakfast was really good. Hotel was clean and modern.

Reviewed on Dec 24, 2025

Kompose Boutique Hotel
Tropical Beach Resorts

Tropical Beach Resorts

3.5 out of 5
6717 Sara Sea Circle Siesta Key FL
Fully refundableReserve now, pay when you stay
$164 nightly
The price is $185 total per night from Jan 4 to Jan 5
$185 total
Jan 4 - Jan 5, 2026
Total with taxes and fees
9.2/10 Wonderful! (5,166 reviews)
Have been staying here for years. Never had a bad experience. Staff is wonderful.

Reviewed on Dec 24, 2025

Tropical Beach Resorts
Compass Hotel by Margaritaville Anna Maria Sound

Compass Hotel by Margaritaville Anna Maria Sound

4 out of 5
12324 Manatee Avenue West Bradenton FL
Fully refundableReserve now, pay when you stay
$228 nightly
The price is $258 total per night from Jan 4 to Jan 5
$258 total
Jan 4 - Jan 5, 2026
Total with taxes and fees
9.4/10 Exceptional! (1,884 reviews)
everthing was

Reviewed on Dec 19, 2025

Compass Hotel by Margaritaville Anna Maria Sound
See all 14,415 properties in Desoto Lakes
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Vacations
All Inclusive Vacations
Beach Vacations
Beach Vacations
Kid Friendly Vacations
Kid Friendly Vacations

Discover the most popular places to visit in Desoto Lakes

Lido Beach showing general coastal views and a sandy beach

Lido Beach

4.5/5(1,225 reviews)

Visit a beach not far from an upscale shopping area. The warm waters are as inviting as the white sand.

Lido Beach
St. Armands Circle featuring a statue or sculpture

St. Armands Circle

4.5/5(1,234 reviews)

Consider this area as a circular outdoor mall. Like any mall, you can shop, dine, browse or just people-watch. Unlike most malls, this one never closes to walkers.

St. Armands Circle
Mall at University Town Center

Mall at University Town Center

4.5/5(363 reviews)

You can search for that perfect souvenir at Mall at University Town Center during your visit to Sarasota. Attend a sporting event or discover the beautiful sunsets in this family-friendly area.

Mall at University Town Center

Things to do

Anna Maria Island and Bradenton Beach: Parasailing Tour

Anna Maria Island & Bradenton Beach Parasailing Tour

$99
per adult
Anna Maria Island & Bradenton Beach Parasailing Tour
Siesta Key, FL - Clear Kayak LED Night Glass Bottom Tour

Siesta Key, FL - Clear Kayak LED Night Glass Bottom Tour

$59
per adult
80% of travellers recommend
Siesta Key, FL - Clear Kayak LED Night Glass Bottom Tour
Robinson Preserve Mangrove Tour

Robinson Preserve Mangrove Tour

$55
per adult
Robinson Preserve Mangrove Tour
See all activities in Sarasota
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.