Desoto Lakes Vacations from $432

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Your Desoto Lakes Vacation

Book a Desoto Lakes vacation package and experience the rhythm and lifestyle of this unique neighborhood. With all your travel plans taken care of, the only thing you need to worry about here is living your best life. Not sure where to go during your trip to Desoto Lakes? Nearby attractions like Mall at University Town Center, Nathan Benderson Park and Ed Smith Stadium are good places to start. Stop dreaming and start doing. When you're ready to book your dream vacation to Desoto Lakes, Expedia is here to help.

The Latest Desoto Lakes Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Mar Bay Motel &Suites

Mar Bay Motel &Suites

2 out of 5
Save 100% on your flight
Price was $681, price is now $432 per person
$432
per person
Mar 14 - Mar 18
found 7 hours ago
Roundtrip flight included
Boston (BOS) to Tampa (TPA)
8.6/10 Excellent! (60 reviews)
Excellent customer service

Reviewed on Dec 14, 2025

voco Sarasota by IHG

voco Sarasota by IHG

3.5 out of 5
Central Sarasota
Save 100% on your flight
Price was $1,708, price is now $1,026 per person
$1,026
per person
Feb 28 - Mar 7
found 2 days ago
Roundtrip flight included
Boston (BOS) to Tampa (TPA)
9.2/10 Wonderful! (1,001 reviews)
Great staff perfect location for our stay.

Reviewed on Jan 27, 2026

Lemon Bay Motel

Lemon Bay Motel

2 out of 5
Englewood Central
Save 100% on your flight
Price was $752, price is now $455 per person
$455
per person
Mar 17 - Mar 24
found 23 hours ago
Roundtrip non-stop flight included
Boston (BOS) to Sarasota (SRQ)
8.4/10 Very Good! (39 reviews)
Staff was great. Clean room but needs new rubber around the door.

Reviewed on Jan 29, 2026

The Barrymore Hotel Tampa Riverwalk

The Barrymore Hotel Tampa Riverwalk

3 out of 5
Downtown Tampa
Price was $1,165, price is now $744 per person
$744
per person
Apr 2 - Apr 9
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to Tampa (TPA)
8.4/10 Very Good! (2,509 reviews)
Clean room and pleasant staff

Reviewed on Jan 25, 2026

Kompose Boutique Hotel

Kompose Boutique Hotel

3 out of 5
Save 100% on your flight
Price was $1,496, price is now $960 per person
$960
per person
Feb 28 - Mar 7
found 2 days ago
Roundtrip flight included
Boston (BOS) to Tampa (TPA)
9.2/10 Wonderful! (4,624 reviews)
Very cool place! Loved the vibe.

Reviewed on Jan 29, 2026

Where to stay in Desoto Lakes

Find the best Desoto Lakes areas and neighborhoods for the activities you enjoy most. Learn more about Desoto Lakes
Sarasota, Florida, USA Downtown Skyline

South Sarasota

While visiting South Sarasota, you might make a stop by sights like The Landings and Coconuts Family Entertainment Center.

Find hotels in South Sarasota

Desoto Lakes Hotel Deals

Golden Host Resort - Sarasota

Golden Host Resort - Sarasota

3 out of 5
4675 N Tamiami Trl Sarasota FL
Fully refundable
$88 nightly
The price is $99 total per night from Feb 1 to Feb 2
$99 total
Feb 1 - Feb 2
Total with taxes and fees
8.4/10 Very Good! (2,244 reviews)
1950s Vintage Tiki Style Motel. Great staff, anything I needed they accosted immediately!

Reviewed on Jan 26, 2026

Golden Host Resort - Sarasota
Kompose Boutique Hotel

Kompose Boutique Hotel

3 out of 5
965 University Pkwy Sarasota FL
Fully refundableReserve now, pay when you stay
$123 nightly
The price is $139 total per night from Feb 1 to Feb 2
$139 total
Feb 1 - Feb 2
Total with taxes and fees
9/10 Wonderful! (4,974 reviews)
Everything clean just obvious the it is a woke company

Reviewed on Jan 28, 2026

Kompose Boutique Hotel
Tropical Beach Resorts

Tropical Beach Resorts

3.5 out of 5
6717 Sara Sea Circle Siesta Key FL
Fully refundableReserve now, pay when you stay
$222 nightly
The price is $250 total per night from Jan 30 to Jan 31
$250 total
Jan 30 - Jan 31
Total with taxes and fees
9.2/10 Wonderful! (5,261 reviews)
Nice

Reviewed on Jan 27, 2026

Tropical Beach Resorts
See all 14,468 properties in Desoto Lakes
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Vacations
All Inclusive Vacations
Beach Vacations
Beach Vacations
Kid Friendly Vacations
Kid Friendly Vacations

Discover the most popular places to visit in Desoto Lakes

Lido Beach showing general coastal views and a sandy beach

Lido Beach

Visit a beach not far from an upscale shopping area. The warm waters are as inviting as the white sand.

Lido Beach
St. Armands Circle featuring a statue or sculpture

St. Armands Circle

Consider this area as a circular outdoor mall. Like any mall, you can shop, dine, browse or just people-watch. Unlike most malls, this one never closes to walkers.

St. Armands Circle
EJETFA The official entrance at the new Mall at University Town Center located just off I-75 on University Parkway in Sarasota Floria

Mall at University Town Center

You can search for that perfect souvenir at Mall at University Town Center during your visit to Sarasota. Attend a sporting event or discover the beautiful sunsets in this family-friendly area.

Mall at University Town Center

Things to do

Kayak Tour through Mangrove Tunnels

Mangroves, Manatees, and a Hidden Beach: Kayak Tour

$59
per adult
92% of travellers recommend
Mangroves, Manatees, and a Hidden Beach: Kayak Tour
Sarasota - Clear Kayak LED Night Glass Bottom Tour

Sarasota - Clear Kayak LED Night Glass Bottom Tour

$65
per adult
80% of travellers recommend
Sarasota - Clear Kayak LED Night Glass Bottom Tour
Anna Maria Island and Bradenton Beach: Parasailing Tour

Anna Maria Island & Bradenton Beach Parasailing Tour

$99
per adult
Anna Maria Island & Bradenton Beach Parasailing Tour
See all activities in Sarasota
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.