Title: Karnes County Vacation Packages 2026 from $452 | Expedia.com

[Karnes County Hotels](https://expedia.com/Destinations-In-Karnes-County.d553248635976429762.Hotel-Destinations)[Vacation Rentals in Karnes County](https://expedia.com/Destinations-In-Karnes-County.d553248635976429762.Vacation-Rental-Destinations)[Karnes County Flights](https://expedia.com/Destinations-In-Karnes-County.d553248635976429762.Flight-Destinations)[Car Rentals in Karnes County](https://expedia.com/Destinations-In-Karnes-County.d553248635976429762.Car-Rental-Destinations)

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# Karnes County Vacations & Trips from $452

## Book a Hotel + Flight or Car together to unlock savings

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### Your Karnes County Vacation

From beginning to end, everything is taken care of when you reserve a Karnes County vacation package. So whether you're coming to experience its walking trails, or any of its other highlights, planning your escape is easy. During your trip to Karnes County, you'll want to tour a few of its most famous cities. A must-see? [Kenedy](https://www.expedia.com/Kenedy.d55138.Destination-Travel-Guides). Whether you're traveling for a few days or a few weeks, Expedia are here to help you tailor-make your next dream Karnes County vacation.

## Top destinations in Karnes County

![South Texas Parks](https://images.trvl-media.com/place/55138/5850280f-5f69-40b7-835c-4287a3ce8a64.jpg?impolicy=fcrop&w=384&h=216&q=medium)

#### Kenedy

[](https://expedia.com/Kenedy.d55138.Destination-Travel-Guides)

![New Braunfels](https://images.trvl-media.com/place/6241289/a23c7f29-02d0-4c83-8844-4a5585840268.jpg?impolicy=fcrop&w=384&h=216&q=medium)

#### Karnes City

[](https://expedia.com/Karnes-City.d6241289.Destination-Travel-Guides)

![San Antonio, Texas, USA cityscape at the River Walk](https://images.trvl-media.com/place/553248621532643645/632bd942-bd19-4647-9183-a0f48225330d.jpg?impolicy=fcrop&w=384&h=216&q=medium)

#### Runge

[](https://expedia.com/Runge.d3000354460.Destination-Travel-Guides)

## The Latest Karnes County Vacation Packages

Price found within the past 48 hours. Click for updated prices.

![The Continental, powered by Placemakr - Downtown - Market Square](https://images.trvl-media.com/lodging/113000000/112180000/112175600/112175524/ab664f86_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

### The Continental, powered by Placemakr - Downtown - Market Square

Downtown San Antonio

$452

per person

May 28 - May 31

found 4 hours ago

Roundtrip non-stop flight included

Philadelphia (PHL) to San Antonio (SAT)

9.6/10 Exceptional! (84 reviews)

nice locations pretty quiet

Reviewed on Mar 14, 2026

![Signia by Hilton La Cantera Resort & Spa](https://images.trvl-media.com/lodging/1000000/290000/284400/284306/w3840h2556x0y4-935acc4f_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

### Signia by Hilton La Cantera Resort & Spa

La Cantera District

Save 100% on your flight

$1,249

per person

Jun 7 - Jun 13

found 1 day ago

Roundtrip non-stop flight included

Boston (BOS) to San Antonio (SAT)

9/10 Wonderful! (1,031 reviews)

Clean room | Amazing staff |

Reviewed on Mar 19, 2026

![Tx Home Group- San Antonio](https://images.trvl-media.com/lodging/114000000/113750000/113748200/113748165/253eb25e_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

### Tx Home Group- San Antonio

Midtown

$556

per person

May 29 - Jun 1

found 1 day ago

Roundtrip non-stop flight included

Philadelphia (PHL) to San Antonio (SAT)

10/10 Exceptional! (6 reviews)

Nightclub area; noisy at night at times; no close shopping; highway driving across town. Initial instructions were confusing but host was great. Pool and gym access; good for active people.

Reviewed on Mar 14, 2026

![The St. Anthony, A Luxury Collection Hotel, San Antonio](https://images.trvl-media.com/lodging/1000000/10000/8800/8789/d1d101fe_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

### The St. Anthony, A Luxury Collection Hotel, San Antonio

Downtown San Antonio

$1,020

per person

Jun 7 - Jun 13

found 1 day ago

Roundtrip non-stop flight included

Boston (BOS) to San Antonio (SAT)

8.8/10 Excellent! (1,004 reviews)

It was a beautiful hotel, easy check in, ans centrally located.

Reviewed on Mar 15, 2026

![The Inn at Market Square](https://images.trvl-media.com/lodging/1000000/10000/6300/6262/229a4017_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

### The Inn at Market Square

Downtown San Antonio

$736

per person

May 5 - May 7

found 22 hours ago

Roundtrip flight included

Boston (BOS) to San Antonio (SAT)

4/10 (661 reviews)

It was all good staff and room

Reviewed on Feb 17, 2026

## Find the Best Karnes County Vacation Packages

## Karnes County Essential Information

| Language        | English                              |
| --------------- | ------------------------------------ |
| Currency        | U.S dollars                          |
| Closest Airport | Austin-Bergstrom Intl. Airport (AUS) |

## Karnes County Hotel Deals

![Holiday Inn Express Kenedy by IHG](https://images.trvl-media.com/lodging/7000000/6330000/6321100/6321095/6e4af116_y.jpg?impolicy=resizecrop&rw=340&ch=150)

### 

Holiday Inn Express Kenedy by IHG

4268 South US Highway 181 Kenedy TX

Fully refundable

$63 nightly

$67 total

Apr 12 - Apr 13

Total with taxes and fees

7.2/10 Good! (108 reviews)

The breakfast was unlike any hotel breakfast we’ve ever had. It was phenomenal!!!!

Reviewed on Mar 20, 2026

[](https://expedia.com/Hotel-Search?startDate=4%2F12%2F2026&endDate=4%2F13%2F2026&selected=6321095&PinnedHotelID=6321095&HadPinnedHotel=true&regionId=553248635976429762)

![Microtel Inn & Suites by Wyndham Kenedy/Karnes City](https://images.trvl-media.com/lodging/8000000/7560000/7552700/7552652/00b98ff5_y.jpg?impolicy=resizecrop&rw=340&ch=150)

### 

Microtel Inn & Suites by Wyndham Kenedy/Karnes City

333 N Sunset Strip St Kenedy TX

Fully refundableReserve now, pay when you stay

$46 nightly

$52 total

Apr 12 - Apr 13

Total with taxes and fees

7.6/10 Good! (306 reviews)

Not clean. No one available to check in at 10pm.

Reviewed on Mar 9, 2026

[](https://expedia.com/Hotel-Search?startDate=4%2F12%2F2026&endDate=4%2F13%2F2026&selected=7552652&PinnedHotelID=7552652&HadPinnedHotel=true&regionId=553248635976429762)

![Royal Inn](https://images.trvl-media.com/lodging/103000000/102730000/102722800/102722707/7e14549f_y.jpg?impolicy=resizecrop&rw=340&ch=150)

### 

Royal Inn

207 S Sunset Strip St Kenedy TX

[Get rates](https://expedia.com/Hotel-Search?startDate=4%2F5%2F2026&endDate=4%2F6%2F2026&selected=102722707&PinnedHotelID=102722707&HadPinnedHotel=true&regionId=553248635976429762)

[](https://expedia.com/Hotel-Search?startDate=4%2F5%2F2026&endDate=4%2F6%2F2026&selected=102722707&PinnedHotelID=102722707&HadPinnedHotel=true&regionId=553248635976429762)

[See all 127 properties in Karnes County](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Package&startDate=3%2F23%2F2026&endDate=3%2F24%2F2026&regionId=553248635976429762)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/all-inclusive_holidays_US.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

All Inclusive Vacations

[](https://expedia.com/lp/theme-vacations/all-inclusive-vacations?rfrr=editorial.All_Inclusive%20Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/XPC_Beach_Overview_HR_v3.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Beach Vacations

[](https://expedia.com/lp/theme-vacations/beach-vacations?rfrr=editorial.Beach_Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/Family_holidays_US_3_.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Kid Friendly Vacations

[](https://expedia.com/lp/theme-vacations/kid-friendly-vacations?rfrr=editorial.Kid_Friendly%20Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2022/04/29/frCA_Sejours_golf-Portugal.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Golf Vacations

[](https://expedia.com/lp/theme-vacations/golf-vacations?rfrr=editorial.Golf_Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2022/07/15/US_Luxury_VR_Miami.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Luxury Vacations

[](https://expedia.com/lp/theme-vacations/luxury-vacations?rfrr=editorial.Luxury_Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2022/08/29/romantic.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Romantic Vacations

[](https://expedia.com/lp/theme-vacations/romantic-vacations?rfrr=editorial.Romantic_Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/31952_v1_atfraraski22_insta_4.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Ski Vacations

[](https://expedia.com/lp/theme-vacations/ski-vacations?rfrr=editorial.Ski_Vacations.click)

![Gay Friendly Vacations](https://forever.travel-assets.com/flex/flexmanager/images/2023/06/15/LGBTQIA_Holiday_Package.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

LGBTQ Friendly Vacations

[](https://expedia.com/lp/theme-holidays/gay-friendly-holidays?rfrr=editorial.LGBTQ_Friendly%20Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2017/07/05/170615_Adventure_1320_2.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Adventure Vacations

[](https://expedia.com/lp/theme-vacations/adventure-vacations?rfrr=editorial.Adventure_Vacations.click)

![Vacations in Month](https://forever.travel-assets.com/flex/flexmanager/images/2023/05/10/mesog-34434-card-venice.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Where to go when

[](https://expedia.com/lp/b/where-to-go-when?rfrr=editorial.Where_to%20go%20when.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/21/honeymoon_hawaii.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Honeymoon Vacations

[](https://expedia.com/lp/theme-vacations/honeymoon-vacations?rfrr=editorial.Honeymoon_Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/23/Mountain-vacations.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Mountain Vacations

[](https://expedia.com/lp/theme-vacations/mountain-vacations?rfrr=editorial.Mountain_Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/23/fishing-vacations-2.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Fishing Vacations

[](https://expedia.com/lp/theme-vacations/fishing-vacations?rfrr=editorial.Fishing_Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2019/05/16/Hyatt%20Zilara%20Cancun%20-%20All%20Inclusive%20-%20Adults%20Only.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Adults Only Vacations

[](https://expedia.com/lp/theme-vacations/adults-only-vacations?rfrr=editorial.Adults_Only%20Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/23/waterpark-vacations.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Waterpark Vacations

[](https://expedia.com/lp/theme-vacations/waterpark-vacations?rfrr=editorial.Waterpark_Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/08/Caribean_scuba_diving.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Scuba Diving Vacations

[](https://expedia.com/lp/theme-vacations/scuba-diving-vacations?rfrr=editorial.Scuba_Diving%20Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/08/aruba_yoga.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Yoga Vacations

[](https://expedia.com/lp/theme-vacations/yoga-vacations?rfrr=editorial.Yoga_Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2023/04/04/EPS-RBC-SummerBeachVacations-AdobeStock_206356322.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Cheap Vacations

[](https://expedia.com/lp/theme-vacations/cheap-vacations?rfrr=editorial.Cheap_Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2024/06/26/1175883311.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Solo Vacations

[](https://expedia.com/lp/b/vacations/solo-vacations?rfrr=editorial.Solo_Vacations.click)

Explore a world of travel with Expedia

## Other vacations you might like

- Top cities in Karnes County
- Vacations and getaways similar to Karnes County
- Best vacation destinations by month

- [Karnes City Vacations ](https://expedia.com/Karnes-City.d6241289.Destination-Travel-Guides)
- [Runge Vacations ](https://expedia.com/Runge.d3000354460.Destination-Travel-Guides)
- [Panna Maria Vacations ](https://expedia.com/Panna-Maria.d553248635967313224.Destination-Travel-Guides)

- [Arkansas Vacations ](https://expedia.com/Arkansas.d205.Destination-Travel-Guides)
- [Louisiana Vacations ](https://expedia.com/Louisiana.d220.Destination-Travel-Guides)
- [Oklahoma Vacations ](https://expedia.com/Oklahoma.d238.Destination-Travel-Guides)
- [New Mexico Vacations ](https://expedia.com/New-Mexico.d233.Destination-Travel-Guides)

- [January Vacations and Deals ](https://www.expedia.com/lp/b/where-to-go/vacations-january)
- [February Vacations and Deals ](https://www.expedia.com/lp/b/where-to-go/vacations-february)
- [March Vacations and Deals ](https://www.expedia.com/lp/b/where-to-go/vacations-march)
- [April Vacations and Deals ](https://www.expedia.com/lp/b/where-to-go/vacations-april)
- [May Vacations and Deals ](https://www.expedia.com/lp/b/where-to-go/vacations-may)
- [June Vacations and Deals ](https://www.expedia.com/lp/b/where-to-go/vacations-june)
- [July Vacations and Deals ](https://www.expedia.com/lp/b/where-to-go/vacations-july)
- [August Vacations and Deals ](https://www.expedia.com/lp/b/where-to-go/vacations-august)
- [September Vacations and Deals ](https://www.expedia.com/lp/b/where-to-go/vacations-september)
- [October Vacations and Deals ](https://www.expedia.com/lp/b/where-to-go/vacations-october)
- [November Vacations and Deals ](https://www.expedia.com/lp/b/where-to-go/vacations-november)
- [December Vacations and Deals ](https://www.expedia.com/lp/b/where-to-go/vacations-december)

\* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.

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