Knoxville Vacations from $697

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to $1,045 when you book a flight and hotel together*
  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package
  • Rest easy

    Plan, book, and manage your trip all in one place

The Latest Knoxville vacation packages

Price found within the past 48 hours. Click for updated prices.
My Home at Columbus
La Quinta Inn & Suites by Wyndham Starkville at MSU
Comfort Inn & Suites Columbus North
Hampton Inn Starkville
Holiday Inn Express & Suites Columbus North by IHG
Don't see what you're looking for?
See all available trips from Columbus to Knoxville
View all trips

The Annual Vacation Sale

Members save up to 40% on hotels and homes. Plan this year’s big trip and save.

Knoxville Hotel Deals

Hotel Capstone

Hotel Capstone

3 out of 5
320 Paul W Bryant Dr Tuscaloosa AL
Fully refundableReserve now, pay when you stay
$110 nightly
The price is $126 total per night from Mar 1 to Mar 2
$126 total
Mar 1 - Mar 2
Total with taxes and fees
9/10 Wonderful! (1,073 reviews)
Outstanding. Comfortable. Friendly staff. I'd stay here again.

Reviewed on Feb 9, 2026

Hotel Capstone
La Quinta Inn & Suites by Wyndham Tuscaloosa University

La Quinta Inn & Suites by Wyndham Tuscaloosa University

3 out of 5
3920 McFarland Blvd. E Tuscaloosa AL
Fully refundableReserve now, pay when you stay
$84 nightly
The price is $96 total per night from Feb 18 to Feb 19
$96 total
Feb 18 - Feb 19
Total with taxes and fees
8.8/10 Excellent! (1,331 reviews)
Friendly cleanliness hospitality and great location

Reviewed on Feb 11, 2026

La Quinta Inn & Suites by Wyndham Tuscaloosa University
Hotel Indigo Tuscaloosa Downtown by IHG

Hotel Indigo Tuscaloosa Downtown by IHG

3.5 out of 5
111 Greensboro Avenue Tuscaloosa AL
Fully refundable
$106 nightly
The price is $122 total per night from Mar 15 to Mar 16
$122 total
Mar 15 - Mar 16
Total with taxes and fees
9/10 Wonderful! (1,002 reviews)
I rented a suite for the weekend. It is very spacious and clean. I personally prefer the city view facing the fluorescent lit park & bridge. There is a wall that is floor to ceiling windows & it is a extremely nice view. The bed was comfortable & bedding for the pull out sofa is conveniently in the ...

Reviewed on Feb 10, 2026

Hotel Indigo Tuscaloosa Downtown by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Knoxville Vacation Packages

Knoxville Essential Information

More vacations you might like

Frequently asked questions

How much does a Knoxville vacation package cost?
Offering excellent value package deals from $697 on Expedia, you'll be thrilled with how little a vacation to Knoxville costs! Expedia's packages make travel planning easier and your savings go further.
What are the cheapest months to go to Knoxville?
September, October and December are the best times to look for cheap Knoxville vacation packages. Choosing to travel in less busy months means you can generally find better prices on flights and accommodations.
How many days is enough for Knoxville?
With a well-organized itinerary, you can easily visit the most popular Knoxville attractions in a few days. But if you want to discover hidden gems or take day trips, think about booking your Knoxville vacation for longer.
How to find the best Knoxville package deals?
Use Expedia's filter tool to help you find some unbeatable Knoxville package deals. When you start your search, just set your maximum budget and then order the results by "Price: low to high." If you're looking to save, plan your break for midweek, or search for Knoxville package deals in the off-season. Switch up your travel dates and you may score even bigger discounts. As a rule of thumb, it's typically best to book your vacation package well in advance.
Is it cheaper to book a Knoxville vacation as a package?
You can enjoy significant savings on your Knoxville retreat by booking a customized vacation package. Click on the "Package" heading, then enter your travel dates and destination to view the best hotel prices and airfares. Bundle everything into a great-value package and you can save hundreds of dollars. Consider adding a car rental and you may land a better deal.
When to book a vacation package to Knoxville?
If you're considering an impromptu Knoxville vacation, browse our last-minute deals that can be booked up to one week before you go. Don't want to leave things to the last minute? You can land awesome deals on your hotels and flights by booking well in advance.
Does Expedia offer Book Now, Pay Later Knoxville vacation packages?
Jet off on your perfect escape to Knoxville with help from our Book Now, Pay Later vacations. No need to save like crazy or hold off until your next payday — we've partnered with online lender Affirm to offer you flexibility and choice. Our vacation packages with payment plans allow you to spread the cost over 3, 6 or 12 months. With no hidden charges or late payment fees, it's easy to budget for your trip and snag great deals before they disappear.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.