Title: Top Independent in Los Osos, CA - Expedia.com [Los Osos Travel Guide](https://expedia.com/Los-Osos.dx9873)[Hotels in Los Osos](https://expedia.com/Los-Osos-Hotels.d9873.Travel-Guide-Hotels)[Vacation Rentals in Los Osos](https://expedia.com/Los-Osos-Vacation-Rentals.d9873.Travel-Guide-VacationRentals)[Flights to Los Osos](https://expedia.com/Cheap-Flights-To-Los-Osos.d9873.Travel-Guide-Flights)[Things to do in Los Osos](https://expedia.com/Things-To-Do-In-Los-Osos.d9873.Travel-Guide-Activities)[Car Rentals in Los Osos](https://expedia.com/Car-Rentals-In-Los-Osos.d9873.Car-Rental-Guide)[Los Osos Vacation Packages](https://expedia.com/Los-Osos.d9873.Destination-Travel-Guides) ![Such a nice place!](https://images.trvl-media.com/place/553248621532639980/2c5ca4d7-c91a-4938-ad4a-7fa3b4914016.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Lisa Travelfeet ![](https://images.trvl-media.com/place/553248621532639980/2c5ca4d7-c91a-4938-ad4a-7fa3b4914016.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Upfront pricing Our total price for your stay includes taxes and fees - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save 10% or more on over 100,000 hotels worldwide with Member Prices [Learn about One Key](https://www.expedia.com/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Mar 6 - Mar 7](https://www.expedia.com/Hotel-Search?regionId=9873&startDate=2026-03-06&endDate=2026-03-07&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Mar 7 - Mar 8](https://www.expedia.com/Hotel-Search?regionId=9873&startDate=2026-03-07&endDate=2026-03-08&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Mar 6 - Mar 8](https://www.expedia.com/Hotel-Search?regionId=9873&startDate=2026-03-06&endDate=2026-03-08&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Mar 13 - Mar 15](https://www.expedia.com/Hotel-Search?regionId=9873&startDate=2026-03-13&endDate=2026-03-15&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.com/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FLos-Osos-Hotels-Independent.0-0-d9873--bIndependent.Travel-Guide-Filter-Hotels)[ Sign up, it's free ](https://expedia.com/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FLos-Osos-Hotels-Independent.0-0-d9873--bIndependent.Travel-Guide-Filter-Hotels) ## Top Los Osos Hotel Reviews ![Edgewater Inn And Suites](https://images.trvl-media.com/lodging/1000000/900000/894000/893902/3beb869e_y.jpg) ### Edgewater Inn And Suites 8/10 Good "The room was clean, there was a little bit of an ocean view from 1 window in the living room, it was nice that there were chairs out on the walk way where we could sit and watch the sunset. There was no air conditioning in the bedrooms so it gets warm when it was 85 degrees..the lamp in the 1 bedroom didnt work because someone broke the ground part of the plug.. the elevator was under construction, but that wasnt even bad" [](https://expedia.com/San-Luis-Obispo-Hotels-Edgewater-Inn-And-Suites.h893902.Hotel-Information) ![La Quinta Inn & Suites by Wyndham San Luis Obispo Downtown](https://images.trvl-media.com/lodging/28000000/27200000/27194600/27194534/d050f4c6_y.jpg) ### La Quinta Inn & Suites by Wyndham San Luis Obispo Downtown 10/10 Excellent "Always a good solid stay when in town for work or personal events! Love their breakfast, always a great option in the area!" [](https://expedia.com/San-Luis-Obispo-Hotels-La-Quinta-Inn-Suites-By-Wyndham-San-Luis-Obispo-Downtown.h27194534.Hotel-Information) ![Spyglass Inn](https://images.trvl-media.com/lodging/1000000/50000/41300/41235/9593cdf6_y.jpg) ### Spyglass Inn 10/10 Excellent "yes" [](https://expedia.com/San-Luis-Obispo-Hotels-Spyglass-Inn.h41235.Hotel-Information) ![Harbor House Inn Morro Bay](https://images.trvl-media.com/lodging/1000000/80000/79600/79558/0ef1fb39_y.jpg) ### Harbor House Inn Morro Bay 10/10 Excellent "Pet friendly, easy access and overall pleasure " [](https://expedia.com/San-Luis-Obispo-Hotels-Harbor-House-Inn-Morro-Bay.h79558.Hotel-Information) ![Apple Farm](https://images.trvl-media.com/lodging/1000000/40000/39500/39435/880cde75_y.jpg) ### Apple Farm 10/10 Excellent "I loved your pillows!" [](https://expedia.com/San-Luis-Obispo-Hotels-Apple-Farm.h39435.Hotel-Information) ![Oxford Suites Pismo Beach](https://images.trvl-media.com/lodging/1000000/10000/3100/3089/010bbafb_y.jpg) ### Oxford Suites Pismo Beach 8/10 Good "Easy access from Highway. Clean. Good value. " [](https://expedia.com/San-Luis-Obispo-Hotels-Oxford-Suites-Pismo-Beach.h3089.Hotel-Information) ![Best Western Casa Grande Inn](https://images.trvl-media.com/lodging/1000000/30000/23100/23008/4cda8af4_y.jpg) ### Best Western Casa Grande Inn 8/10 Good "For the most part the stay was good, it was quiet and the room was ok. The door leading out of the room lead to a drop-off at the edge of the walkway, so if you weren't careful, you could step off a high edge and take a fall and injure yourself. I had to have the hotel get a safety cone to put in front, so I didn't accidently walk off that edge and injure myself. The shower head in our room was fixed so you could not adjust it, if you were 6'6" tall it's not a problem but for anyone else the shower water is spraying right over your head. If we had a different room the stay might have been better. " [](https://expedia.com/San-Luis-Obispo-Hotels-Best-Western-Casa-Grande-Inn.h23008.Hotel-Information) ![SeaCrest OceanFront Hotel](https://images.trvl-media.com/lodging/2000000/1370000/1365400/1365352/b40c24d9_y.jpg) ### SeaCrest OceanFront Hotel 10/10 Excellent "Such a beautiful property " [](https://expedia.com/San-Luis-Obispo-Hotels-SeaCrest-OceanFront-Hotel.h1365352.Hotel-Information) ![Quality Suites Downtown San Luis Obispo](https://images.trvl-media.com/lodging/1000000/10000/3200/3138/b42da2cd_y.jpg) ### Quality Suites Downtown San Luis Obispo 10/10 Excellent "Excellent " [](https://expedia.com/San-Luis-Obispo-Hotels-Quality-Suites-Downtown-San-Luis-Obispo.h3138.Hotel-Information) ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rentals - Other - [Marriott Hotels & Resorts in Baywood-Los Osos ](https://www.expedia.com/Baywood-Los-Osos-Hotels-Marriott-Hotels-Resorts.0-0-d553248634983100425--bMarriottHotelsResorts.Travel-Guide-Filter-Hotels) - 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