Title: Top Independent in Los Osos, CA - Expedia.com [Los Osos Travel Guide](https://expedia.com/Los-Osos.dx9873)[Hotels in Los Osos](https://expedia.com/Los-Osos-Hotels.d9873.Travel-Guide-Hotels)[Vacation Rentals in Los Osos](https://expedia.com/Los-Osos-Vacation-Rentals.d9873.Travel-Guide-VacationRentals)[Flights to Los Osos](https://expedia.com/Cheap-Flights-To-Los-Osos.d9873.Travel-Guide-Flights)[Things to do in Los Osos](https://expedia.com/Things-To-Do-In-Los-Osos.d9873.Travel-Guide-Activities)[Car Rentals in Los Osos](https://expedia.com/Car-Rentals-In-Los-Osos.d9873.Car-Rental-Guide)[Los Osos Vacation Packages](https://expedia.com/Los-Osos.d9873.Destination-Travel-Guides) ![Such a nice place!](https://images.trvl-media.com/place/553248621532639980/2c5ca4d7-c91a-4938-ad4a-7fa3b4914016.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Lisa Travelfeet ![](https://images.trvl-media.com/place/553248621532639980/2c5ca4d7-c91a-4938-ad4a-7fa3b4914016.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Upfront pricing Our total price for your stay includes taxes and fees - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save 10% or more on over 100,000 hotels worldwide with Member Prices [Learn about One Key](https://www.expedia.com/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Mar 8 - Mar 9](https://www.expedia.com/Hotel-Search?regionId=9873&startDate=2026-03-08&endDate=2026-03-09&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Mar 9 - Mar 10](https://www.expedia.com/Hotel-Search?regionId=9873&startDate=2026-03-09&endDate=2026-03-10&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Mar 13 - Mar 15](https://www.expedia.com/Hotel-Search?regionId=9873&startDate=2026-03-13&endDate=2026-03-15&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Mar 20 - Mar 22](https://www.expedia.com/Hotel-Search?regionId=9873&startDate=2026-03-20&endDate=2026-03-22&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.com/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FLos-Osos-Hotels-Independent.0-0-d9873--bIndependent.Travel-Guide-Filter-Hotels)[ Sign up, it's free ](https://expedia.com/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FLos-Osos-Hotels-Independent.0-0-d9873--bIndependent.Travel-Guide-Filter-Hotels) ## Top Los Osos Hotel Reviews ![Best Western Casa Grande Inn](https://images.trvl-media.com/lodging/1000000/30000/23100/23008/4cda8af4_y.jpg) ### Best Western Casa Grande Inn 8/10 Good "Mostly great. Parking is tough if you have a large vehicle " [](https://expedia.com/San-Luis-Obispo-Hotels-Best-Western-Casa-Grande-Inn.h23008.Hotel-Information) ![SeaCrest OceanFront Hotel](https://images.trvl-media.com/lodging/2000000/1370000/1365400/1365352/b40c24d9_y.jpg) ### SeaCrest OceanFront Hotel 10/10 Excellent "Ocean view marred by plantation shutters over half the sliding doors, leaving a space only about 24 inches wide to gaze outside the room at the ocean view. " [](https://expedia.com/San-Luis-Obispo-Hotels-SeaCrest-OceanFront-Hotel.h1365352.Hotel-Information) ![Spyglass Inn](https://images.trvl-media.com/lodging/1000000/50000/41300/41235/9593cdf6_y.jpg) ### Spyglass Inn 6/10 Okay "We didn’t have pets. Balcony nice " [](https://expedia.com/San-Luis-Obispo-Hotels-Spyglass-Inn.h41235.Hotel-Information) ![Oxford Suites Pismo Beach](https://images.trvl-media.com/lodging/1000000/10000/3100/3089/010bbafb_y.jpg) ### Oxford Suites Pismo Beach 10/10 Excellent "Nice " [](https://expedia.com/San-Luis-Obispo-Hotels-Oxford-Suites-Pismo-Beach.h3089.Hotel-Information) ![Harbor House Inn Morro Bay](https://images.trvl-media.com/lodging/1000000/80000/79600/79558/0ef1fb39_y.jpg) ### Harbor House Inn Morro Bay 10/10 Excellent "This place was great! Wasn't expecting anything mind blowing, but this place delivered on cleanliness, kindness, and flexibility. We had a late arrival & the staff made it super easy to access our room. They also granted us a little bit later check out since we were surfing in the AM on our last day. The room was huge! Bed was soft but not too soft. The window covering was fun with the Morro Bay rock image & the privacy screen. Room had everything needed to make our weekend stay comfy and cozy. The on site staff was so friendly. Restaurants and coffee shops easily walkable as was the bay. Will definitely stay again! " [](https://expedia.com/San-Luis-Obispo-Hotels-Harbor-House-Inn-Morro-Bay.h79558.Hotel-Information) ![Cottage Inn By The Sea](https://images.trvl-media.com/lodging/1000000/160000/151000/150921/a9c907e0_y.jpg) ### Cottage Inn By The Sea 10/10 Excellent "Room had a great view of ocean " [](https://expedia.com/San-Luis-Obispo-Hotels-Cottage-Inn-By-The-Sea.h150921.Hotel-Information) ![Embassy Suites by Hilton San Luis Obispo](https://images.trvl-media.com/lodging/1000000/20000/15500/15406/be1d8b89_y.jpg) ### Embassy Suites by Hilton San Luis Obispo 8/10 Good "Was there one day..Room's were very clean breakfast was real cal poly eggs..." [](https://expedia.com/San-Luis-Obispo-Hotels-Embassy-Suites-By-Hilton-San-Luis-Obispo.h15406.Hotel-Information) ![Sandcastle Hotel on the Beach](https://images.trvl-media.com/lodging/1000000/50000/41000/40915/99213fd0_y.jpg) ### Sandcastle Hotel on the Beach 10/10 Excellent "Yes and yes. Very nice. " [](https://expedia.com/San-Luis-Obispo-Hotels-Sandcastle-Hotel-On-The-Beach.h40915.Hotel-Information) ![Inn at the Pier Pismo Beach, Curio Collection by Hilton](https://images.trvl-media.com/lodging/19000000/18680000/18676000/18675941/2b68211d_y.jpg) ### Inn at the Pier Pismo Beach, Curio Collection by Hilton 10/10 Excellent "I believe the gentleman’s name was either Eric or Paul but he worked the evening shift during our stay. He was the BEST and so kind to our toddler. He was helpful with suggestions and overall such a sweetheart" [](https://expedia.com/San-Luis-Obispo-Hotels-Inn-At-The-Pier.h18675941.Hotel-Information) ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rentals - Other - [Marriott Hotels & Resorts in Baywood-Los Osos ](https://www.expedia.com/Baywood-Los-Osos-Hotels-Marriott-Hotels-Resorts.0-0-d553248634983100425--bMarriottHotelsResorts.Travel-Guide-Filter-Hotels) - [Best Western Hotels in Baywood-Los Osos ](https://www.expedia.com/Baywood-Los-Osos-Hotels-Best-Western.0-0-d553248634983100425--bBestWestern.Travel-Guide-Filter-Hotels) - [Pet-Friendly Hotels in Baywood-Los Osos ](https://www.expedia.com/Baywood-Los-Osos-Hotels-Pet-Friendly-Hotel.0-0-d553248634983100425-tPetfriendlyHotel.Travel-Guide-Filter-Hotels) - [Baywood-Los Osos Hotels ](https://www.expedia.com/Baywood-Los-Osos-Hotels.d553248634983100425.Travel-Guide-Hotels) - [Condo Rentals in Baywood-Los Osos ](https://www.expedia.com/Baywood-Los-Osos-Condos.d553248634983100425-aaCondos.Travel-Guide-Accommodation) - 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