
Mission Bay Vacations from $220
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Your Mission Bay Vacation
Make travel planning easier by creating a vacation package to Mission Bay. We'll take care of the finer points, so you can concentrate on savoring everything this neighborhood can offer. Kick off your trip to Mission Bay by heading to nearby attractions such as Pier 39, Lombard Street and Oracle Park. Whatever your travel goals or budget, booking your perfect Mission Bay vacation is a cinch with Expedia.
The Latest Mission Bay Vacation Packages

Aqua Breeze Inn
Reviewed on Dec 3, 2025

1 Hotel San Francisco
Reviewed on Dec 7, 2025

Montage Healdsburg
Reviewed on Nov 30, 2025

Claremont Resort & Club
Reviewed on Dec 3, 2025

Treehouse Hotel Silicon Valley
Reviewed on Nov 23, 2025
Where to stay in Mission Bay

Union Square
Major tourist destination in downtown San Francisco, Union Square boasts shopping, hotels, and theaters. Explore department stores, boutiques, and galleries, or catch a performance at various theaters. Enjoy the Dewey Monument and stunning views from nearby hotels. Easily accessible via cable car lines, buses, and subway systems.
Mission Bay Hotel Deals

LUMA Hotel San Francisco
Staff was very welcoming and helpful. Directed us toward late night snacks.
Reviewed on Dec 3, 2025

Holiday Inn Golden Gateway by IHG
Clean room, courteous staff, walking distance to lots of eateries.
Reviewed on Dec 4, 2025

Hotel Riu Plaza Fisherman's Wharf
The room and hotel was clean. The staff was friendly. The hotel was a great location. Couldn’t ask for anything else.
Reviewed on Dec 5, 2025
Discover the most popular places to visit in Mission Bay
Chase Center
Catch an event at Chase Center during your trip to San Francisco. Amble around this vibrant area's Chinatown or experience its entertainment choices.
Things to do

California Academy of Sciences Daytime Admission

San Francisco City Lights Cruise (2-hours)























