Pendleton, SC Vacation Homes from $206

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Our top choices for Pendleton vacation homes

A hot tub with steam rising from it, wooden beams on the ceiling, and a view of the outside.

1. The Rustic Rectangle

Pendleton

Jennifer T.

$188 nightly

Nov 16 - Nov 17

Total with taxes and fees

A room with a sliding barn door, a blue patterned armchair, and a chandelier.

2. Clemson Memorabilia House Frank Howard III’s Home

Clemson

Libby S.

$234 nightly

Dec 1 - Dec 2

Total with taxes and fees

3. Modern and Spacious 2-floor Townhome Close to CU!

Clemson

"Check in was horrible and the unit was not ready. We had no showings due to all bathrooms didn’t work. We had nothing in the unit, ie, towels, tv remote, coffee maker, toaster, trash cans, unit had dead bugs and was not cleaned properly. We left a day early due to all these issues. We have multiple times requested a refund due to the inconvenience after we drove 8 hours to Clemson. We basically were your tenants that committed all these issues to make it better for the next VRBO customer. That...

Michael W.

$321 nightly

Nov 16 - Nov 17

Total with taxes and fees

A circular seating area with wooden Adirondack chairs around a central fire pit, surrounded by a grassy area with trees and a picnic table in the background.

4. Lake Retreat- Mins to CU- Kayaks, Fire Pit, Dock

Seneca

Diana H.

$262 nightly

Nov 29 - Nov 30

Total with taxes and fees

A spacious kitchen with a large island, built-in appliances, and a dining area with a sofa.

5. Peaceful 3-bedroom home 4 miles from Clemson.

Seneca

Justin K.

$258 nightly

Nov 30 - Dec 1

Total with taxes and fees

A dining area with a wooden table set for four, surrounded by chairs, in a room with hardwood flooring and white walls.

6. Large 3 Bedroom Townhome Downtown Clemson and garage! Walk to Clemson Stadium!

Clemson

$399 nightly

Nov 16 - Nov 17

Total with taxes and fees

A sunroom with wicker furniture, large windows, and a ceiling fan.

7. Beautiful Updated Clemson Lake House - 4 Miles from Downtown Clemson and the Stadium

Seneca

Allison C.

$596 nightly

Nov 16 - Nov 17

Total with taxes and fees

A wooden sauna structure with a person inside, surrounded by trees and a wooden deck.

8. Clemson | Lakefront | HotTub | Sauna | Gym | SUPs

Townville

$590 nightly

Dec 2 - Dec 3

Total with taxes and fees

A two-story house with a balcony, wooden deck, and string lights.

9. Clemson|SUPs|ParkPass|PizzaOven|PortmanMarina|EV

Anderson

Leah N.

$451 nightly

Dec 1 - Dec 2

Total with taxes and fees

A deck with a table and chairs, overlooking a river and trees.

10. Spacious 5-bedroom waterfront estate in welcoming Anderson

Anderson

Gina N.

$348 nightly

Nov 16 - Nov 17

Total with taxes and fees

A covered outdoor seating area with a wooden table and benches, surrounded by a railing and overlooking a garden.

11. 2 Bedroom Lake Front Tiny Home in Anderson, beside Legendary Green Pond Landing

Anderson

Lisa B.

$304 nightly

Dec 1 - Dec 2

Total with taxes and fees

A cozy living room with a sofa, armchair, and coffee table, featuring a view of a deck and outdoor furniture.

12. Lake Hartwell Waterfront Getaway Private Covered Dock Near Clemson

Anderson

Bryan S.

$543 nightly

Dec 1 - Dec 2

Total with taxes and fees

A kitchen with white cabinets, a black refrigerator, a stove, a microwave, and a window with blinds.

13. Charming 2-Bd 1-Ba home in Easley near GVL & Clemson w/WiFi, self check-in & AC

Easley

David

$186 nightly

Nov 16 - Nov 17

Total with taxes and fees

14. Stylish Home Pvt Rooms w/ Pvt Baths Minutes to Shopping & Dining - Boat Parking

Anderson

$293 nightly

Nov 16 - Nov 17

Total with taxes and fees

15. 2BR Home w/ Private Baths | Pets | Anderson SC

Anderson

$321 nightly

Nov 30 - Dec 1

Total with taxes and fees

A white two-story house with a front porch, a double door, and a number '204' on the door.

16. Renovated 3BR near Lake Keowee & Clemson

Seneca

Brenda B.

$318 nightly

Nov 16 - Nov 17

Total with taxes and fees

A wooden deck with a railing overlooking a forested area during sunset.

17. Waterfront 3br home on Lake Hartwell near Clemson

Seneca

Diane S.

$448 nightly

Nov 16 - Nov 17

Total with taxes and fees

A bedroom with a bed, a dresser, a mirror, a ceiling fan, and windows with curtains.

18. Come for the location. Stay for the vibe.

Anderson

$348 nightly

Nov 17 - Nov 18

Total with taxes and fees

A modern kitchen with white cabinets, a stainless steel microwave, a gas stove, and a coffee maker.

19. Cozy 2-bedroom bungalow in delightful Anderson with AC

Anderson

$156 nightly

Nov 24 - Nov 25

Total with taxes and fees

A wooden deck with a bench, table, and chairs, surrounded by a wooden railing and trees.

20. Lakefront Retreat l Near Clemson, Hot Tub, Game Room, Kayaks, Private Dock

Seneca

Scott M.

$742 nightly

Nov 16 - Nov 17

Total with taxes and fees

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Learn more about Pendleton

Discover Pendleton's rich history at the Pendleton Historic District, where guided tours reveal fascinating stories of the town's past. The Village Green hosts farmers markets and festivals, while nearby Lake Hartwell offers excellent fishing and boating opportunities.

See all hotels in Pendleton

A multi-tiered waterfall surrounded by dense forest.

Top reviews in Pendleton

A spacious hallway with a wooden ceiling, a sofa, a chair, and a lamp.

The Inn at Patrick Square

Clemson

10/10 Excellent

SHARRA

A modern bar area with a menu board, bar stools, and a countertop with various items.

Courtyard Marriott Clemson

Clemson

10/10 Excellent

Anonymous traveler

A room with a wooden floor, a blue patterned armchair, a large chandelier, and a sliding barn door.

Clemson Memorabilia House

Clemson

10/10 Excellent

Marissa

A golf course with a water body, trees, and a distant view of a bridge.

Clemson University's James F. Martin Inn

Clemson

10/10 Excellent

Margot

A Holiday Inn Express & Suites hotel with a modern architectural design, featuring a prominent entrance with columns and a flat roof.

Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG

Anderson

10/10 Excellent

Ruth

A hotel lobby with a reception desk, potted plants, and a tiled floor.

Hilton Garden Inn Anderson

Anderson

10/10 Excellent

THOMAS

A reception area with a reception desk, a sofa, a staircase, and a wall with artwork.

Inn @ Clemson

Clemson

10/10 Excellent

Changsong

A cabin with a cozy interior, a wooden exterior, and a view of the forest.

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Seneca

10/10 Excellent

Jonathan

A multi-story hotel with a swimming pool, landscaped grounds, and a parking area.

Lakeside Lodge Clemson

Seneca

10/10 Excellent

Maria

A multi-level interior with a spiral staircase, wooden railings, and a seating area with tables and chairs.

The Shepherd Hotel Downtown Clemson

Clemson

10/10 Excellent

Amy

A modern living room with a stone wall, a fireplace, and a large window. There are two sofas, a coffee table, and a dining area with a table and chairs.

Fairfield Inn & Suites by Marriott Anderson Clemson

Anderson

10/10 Excellent

This hotel is way better than I thought. Rooms are clean and I can tell by looking at the carpet. Carpet looks brand new on the 2nd floor (that where my room was) No ghettoness around here. It’s located near bunch of restaurants so it’s nice if you are hungry. Room smelled funny when I first walked in but I sprayed some cologne so it’s all good. AC and heat works great. And it’s room is peaceful, nicely decorated Shower pressure is nice and showers tub is clean too!

Im Rick James