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Compare 84 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Outdoor dining
WELCOME TO WESTHOFF CAMPGROUND BUNKHOUSE
10.0 out of 10, Exceptional, (7)
"Property was just as described. It’s a great place for those that don’t mind sharing living quarters. Hostess was great too…"
WELCOME TO WESTHOFF CAMPGROUND BUNKHOUSE
Beach
Mark Twain lake getaway at Blue Lagoon!
10.0 out of 10, Exceptional, (19)
"Exactly as described. The host was very good with communication and seemed to be very genuine in wanting us to have a great stay! We would definitely rent again"
Mark Twain lake getaway at Blue Lagoon!
Fridge, microwave, oven, stovetop
SPENCER FAMILY FARMHOUSE-minutes from Indian Creek Marina on Mark Twain Lake.
10.0 out of 10, Exceptional, (9)
"The house was perfect for a weekend at the lake! The kitchen provided ample space and resources for meal prep. The grill and fire pit were an added bonus. The beds were comfy. The location was perfect as it is only a few miles from the marina and a few miles from Monroe City. The 20 minute drive to Sweetwater Distillery is a must!"
SPENCER FAMILY FARMHOUSE-minutes from Indian Creek Marina on Mark Twain Lake.
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Fridge, microwave, oven, stovetop
Salty Cedar Cabin #5
10.0 out of 10, Exceptional, (3)
"Great location Great property"
Salty Cedar Cabin #5
Fridge, microwave, oven, stovetop
Mark Twain Lake Condo
9.8 out of 10, Exceptional, (29)
"As always a wonderful stay"
Mark Twain Lake Condo
Fridge, microwave, oven, stovetop
Mark Twain lake getaway.
9.8 out of 10, Exceptional, (24)
"Beautiful home and awesome property! Very peaceful and we enjoyed our stay although it was short we will be back again. Awesome host as well!"
Mark Twain lake getaway.
Beach
Mark Twain Lake Cabin - Hunting Fishing and Boating
9.8 out of 10, Exceptional, (12)
"2nd stay at this location. Clean, great condition, very responsive owners. Couldn’t ask for a better rental."
Mark Twain Lake Cabin - Hunting Fishing and Boating
Fridge, microwave, oven, stovetop
Salty Cedar Cabins #2
9.6 out of 10, Exceptional, (5)
"Very clean, close to everything"
Salty Cedar Cabins #2
Fridge, microwave, oven, stovetop
Salty Cedar Cabins #3
9.4 out of 10, Exceptional, (6)
"Love staying here. This is our 2nd trip to Salty Cedar Cabins. We love the location in proximity to the Spaulding boat ramp. The owner is great to work with. We will definitely be back next year."
Salty Cedar Cabins #3
Free self parking
Kennedys Red Barn Inn
2.5 star property
9.2 out of 10, Wonderful, (24)
"We were only there literally to sleep as we were traveling and it was the half way mark on the trip. We wish we could have stayed and enjoyed the stay! It is a very unique place with amazingly kind innkeepers!!"
The price is $96
$102 total
includes taxes & fees
May 18 - May 19
Kennedys Red Barn Inn
Fridge, microwave, oven, stovetop
Salty Cedar Cabins #1
9.0 out of 10, Wonderful, (10)
"The cabin was well stocked with essentials, very clean. Appliances and amenities are in great shape. Good proximity to local attractions. Just watch out for the local crow if you leave any food outside."
Salty Cedar Cabins #1
Exterior
Salty Cedar Cabin #4
8.8 out of 10, Excellent, (3)
"Perfect place to stay on a weekend trip to Twain. Plenty of places to plug a boat in. Host is very responsive. We will definitely stay here again."
Salty Cedar Cabin #4
Standard Single Room, 2 Queen Beds, Non Smoking | Iron/ironing board, free WiFi, bed sheets
The Junction Inn
2.0 star property
7.2 out of 10, Good, (7)
"Great place to stay "
The price is $81
$97 total
includes taxes & fees
May 17 - May 18
The Junction Inn
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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Center Travel Info

Number of reviews
5,419
Accommodation
84 hotels
Highest price
$117
Lowest price
$60

Frequently asked questions

Where is the best place for a stay in Center?

Based on Expedia's traveler preferences, WELCOME TO WESTHOFF CAMPGROUND BUNKHOUSE is a top place to stay in Center. Other good options for your visit to the area are Best Western On The River and Quality Inn & Suites Hannibal. See all available top hotels, or vacation rentals in Center.

If I need to cancel my hotel reservation in Center, will I receive a refund?

Yes, the majority of hotel reservations are fully refundable provided that you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your check-in date. If you have a non-refundable reservation, you might be able to cancel it and be given a refund within 24 hours of booking. Filter your search by fully refundable to find flexible hotel deals in Center.

Where can I learn more about changing or cancelling my trip to Center?

For more information about updating your trip to Center or cancelling it, go to https://www.expedia.com/service/.

What are some accommodations with pools in Center?

Quality Inn & Suites Hannibal: Features a snack bar, an indoor pool, and free buffet breakfast. Best Western On The River and Holiday Inn Express And Suites Hannibal - Medical Center, an IHG Hotel are a couple of other choices that feature an onsite pool. View all hotels with pools in Center.

What is staying in Center like?

Travelers to Center will find plenty to explore and enjoy. In Center, there are 2 hotels and other accommodations to choose from. Find out more about Center.

What are the top places to visit in Center?

A favorite place to visit is Mark Twain Lake. You'll also find Mark Twain State Park and Mark Twain Cave in the area. Check out what more to see and do in Expedia's Center guide.

What's the weather like in Center?

The hottest months are usually July and August with an average temp of 74°F, while the coldest months are January and February with an average of 35°F. Average annual precipitation for Center is 47 inches.

Recent reviews of Center hotels
Expedia verified reviews