A large eye sculpture in a park surrounded by trees.

Find hotels in Northeast Missouri, MO from $72

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Aug 30 - Aug 31
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Aug 31 - Sep 1
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Our top choices for Northeast Missouri hotels

A living room with a sofa, coffee table, and patterned rug. There are large windows with blinds, a chandelier, and a view of the outside.
A building with a covered entrance, American flag, and a sign indicating it's open.
A hotel room with two beds, a television, a lamp, and a painting on the wall.
A dining area with multiple tables and chairs, a kitchen area with a refrigerator and various kitchen items, and a window with curtains.

1. FairBridge Inn Express, Monroe City

FairBridge Inn Express, Monroe City
Monroe City
United States
Darrin J.
$84 nightly
$91 total
Sep 1 - Sep 2
Total with taxes and fees
FairBridge Inn Express, Monroe City
A hotel room with a bed, a sofa, a desk, a chair, and a small table.
A kitchenette with a coffee maker, toaster, microwave, and various kitchen utensils.
A Super 8 hotel with a covered entrance and multiple windows.
A hotel room with a bed, a desk with a computer, a chair, a TV, and a window with curtains.

2. Super 8 by Wyndham Macon

Super 8 by Wyndham Macon
Macon
United States
Austin
$84 nightly
$92 total
Sep 11 - Sep 12
Total with taxes and fees
Super 8 by Wyndham Macon
A compact kitchen with wooden cabinets, a coffee machine, and a dining area with metal chairs.
A neatly made bed with a brown quilted bedspread, a decorative pillow with a heart-shaped towel, and a bedside table with a lamp.
A hotel lobby with a black leather sofa, two bar stools, a reception desk, and a sign indicating no refund policy.
A compact kitchenette with a microwave, a small refrigerator, a coffee maker, and a telephone on a wooden dresser.

3. Americas Best Value Inn & Suites Macon at Sunset Dr

Americas Best Value Inn & Suites Macon at Sunset Dr
Macon
United States
Mary
$70 nightly
$75 total
Sep 8 - Sep 9
Total with taxes and fees
Americas Best Value Inn & Suites Macon at Sunset Dr
A hotel room with two beds, green walls, and artwork.
A row of motel buildings with a parking lot in front.
A hallway with a wooden door, a black refrigerator, and a microwave on top.
A laundry room with two washing machines, a dryer, and a wall-mounted heater.

4. Travelier Motel

Travelier Motel
Macon
United States
Jessica
$68 nightly
$74 total
Aug 31 - Sep 1
Total with taxes and fees
Travelier Motel
A neatly made bed with a white quilt, a dark wooden headboard, a bedside lamp, a red chair, and a wall decoration.
A hotel lobby with a Christmas tree, red sofas, a wooden reception desk, and a sign for Simple Rewards Inn.
A long, narrow hallway with carpeted floors, doors on both sides, and a red chair in the distance.
A room with a large window, a red chair, and a wall-mounted air conditioner.

5. Prairie View Inn

Prairie View Inn
Shelbina
United States
Randy
$85 nightly
$93 total
Aug 31 - Sep 1
Total with taxes and fees
Prairie View Inn
A wooden bridge with a rope railing in a forested area.
A modern kitchen with wooden cabinets, stainless steel appliances, and a large island.
A spacious living room with a high ceiling, wooden beams, a fireplace, and a dining area with a table and chairs.
A wooden staircase with a railing, a door, and a ceiling with fluorescent lights.

6. Lost Branch Lodge. Complete exterior remodel, spring 2026!

Lost Branch Lodge. Complete exterior remodel, spring 2026!
Brashear
United States
Melissa W.
Lost Branch Lodge. Complete exterior remodel, spring 2026!
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Vacation Rentals in Northeast Missouri

Cabin
A park with a pond, picnic tables, and a gazebo.
A pool with a 5 FT depth marker.
A grassy area with a picnic table and a dog.
A row of rustic, single-story buildings with a grassy lawn and picnic tables.

Cannon Dam Cabins

Cannon Dam Cabins
Perry
"Cozy and well equipped with everything we may have needed"
Cannon Dam Cabins
Aparthotel
A hotel room with a large bed, two bedside lamps, a modern bathroom, and a vibrant abstract painting on the wall.
A compact kitchen with white cabinets, a microwave, a coffee maker, and a sink.
A spacious bathroom with a large bathtub, a walk-in shower, and a vanity with a mirror.
A modern living room with a grey sofa, a white armchair, a coffee table, and a patterned rug. There is a kitchen in the background with white cabinets and a black door.

Lighthouse Inn & Suites

Lighthouse Inn & Suites
Hannibal
"Wonderful place to stay!"
Lighthouse Inn & Suites
Apartment
A spacious foyer with a grand staircase, a piano, and a large rug.
A hallway with wooden doors, a wall-mounted tree decoration, a small table with a plant, and a painting.
A spacious dining area with a round glass table, black metal chairs, and a wooden staircase leading to an upper level.
A spacious living room with a beige sofa, a dining area with a table and chairs, large windows, and a chandelier.

White House at Grand Central

White House at Grand Central
Grand Center
"Staff was great and accommodating to my needs."
White House at Grand Central
Apartment
A modern hotel lobby with a marble reception desk, a TV mounted on the wall, and a seating area with chairs and a sofa.
A modern living room with a pool table, a seating area, and a large window offering a view of the outdoors.
A swimming pool with lounge chairs, a bar area, and a building with multiple balconies.
A modern living area with a grey sofa, a glass coffee table, and a black leather sofa. There are large windows and a visible interior space beyond.

Landing Furnished Apartments - Central West End

Landing Furnished Apartments - Central West End
Central West End
"We booked a two bedroom for three people and the 2nd bedroom didn't have a bed! Contacted property, which was very responsive, but they couldn't do anything since we booked through Hotels. com"
Landing Furnished Apartments - Central West End
Cottage
A modern living room with a grey sofa, a dining table with chairs, a small side table, and a floor lamp.
A kitchen with white cabinets, a granite countertop, a stainless steel refrigerator, a microwave, a toaster, and a coffee maker.
A modern kitchen with white cabinets, a black refrigerator, and a dining area with a blue table runner.
A living room with a sofa, a table, a TV, and a dining area with chairs.

Peaceful Missouri Cabin Rental on 55 Acres!

Peaceful Missouri Cabin Rental on 55 Acres!
Canton
"This is a great place to stay if you want to get away from the city. Rural enough to be quiet, but within easy driving distance to a city. Also perfect if you just want to stay on the property and really get away from city life, just bring your groceries. "
Peaceful Missouri Cabin Rental on 55 Acres!
Vacation Home
A modern kitchen with dark cabinetry, a marble countertop, and a central island.
A room with bunk beds, a desk with a computer, and a TV.
A modern kitchen with dark cabinetry, a central island, and a dining area with a wooden table and chairs.
A modern kitchen with dark cabinets, a large island with a marble countertop, and stainless steel appliances.

Remodeled and Inviting Free EV

Remodeled and Inviting Free EV
Fenton
"It was nice to stay for a weekend but the neighborhood was nice I like the location where it wasn't too far from grocery stores food areas the only thing I was saying is it's nothing for the kids to do but overall I like it"
Remodeled and Inviting Free EV
Apartment
A bedroom with a bed, a dresser, a TV, and a door leading to another room.
A dining area with a white table and brown chairs, a vase with yellow flowers, and a ceiling light fixture.
A living room with a sectional sofa, a round coffee table, a fireplace, and a television mounted on the wall.

Botanical Bliss | JZ Vacation Rentals

Botanical Bliss | JZ Vacation Rentals
Southwest Garden
Botanical Bliss | JZ Vacation Rentals
Apartment
A spacious room with a wooden dining table, chairs, a chandelier, and a bed with white bedding.
A red deck with wicker furniture and a blue umbrella, overlooking a residential area with houses and a dome-shaped building.
A modern living room with a blue sofa, a coffee table, and a ceiling fan.
A bedroom with a bed, a desk, a chair, a bench, and a ceiling fan.

Spacious 3-Bedroom with King Bed

Spacious 3-Bedroom with King Bed
Central West End
"Clean room nice area "
Spacious 3-Bedroom with King Bed
Cottage
A covered porch with metal siding, a white door, and two folding chairs.
A living room with a beige sofa, a coffee table, a TV mounted on the wall, and a chair.
A modern kitchen with white cabinets, a black refrigerator, and a dining area with a wooden table and chairs.
A bedroom with a bed, a desk with a chair, a dresser, a ceiling fan, and a window with blinds.

Updated Missouri Cabin Rental on Large Farm

Updated Missouri Cabin Rental on Large Farm
Canton
"The cabin rental was a great stay. Had some connection problems with the t.v. couldn't get past the check out date. The wifi was easy to hook up. The cabin was clean and smelled fresh. Did have some problems with ants on the countertop. Great place to stay, enjoyed our visit."
Updated Missouri Cabin Rental on Large Farm
Vacation Home
A dining table with a clear glass top, surrounded by two chairs, a potted plant, and a set of white tableware.
A living room with two armchairs, a large wall clock, a wooden staircase, and a welcome sign.
A modern living room with a blue sofa, a fireplace, a ceiling fan, and a TV mounted above the fireplace.
A two-story brick house with a front porch, a stone foundation on one side, and a wooden deck on the other.

Forest Park Oasis | JZ Vacation Rentals

Forest Park Oasis | JZ Vacation Rentals
Kings Oak
"Great property with plenty of space. Nice sized dining room table for dinner. Beautiful family room and fire place. Nicely decorated. "
Forest Park Oasis | JZ Vacation Rentals
Apartment
A wooden deck with a rope fence, overlooking a lake and surrounded by trees.
A two-story house with a covered porch and a detached garage.
A spacious living area with a sofa, a coffee table, and a dining table with a bench. There is a ceiling fan and a chandelier.
A kitchen with a large island, wooden cabinets, and a view of a lake.

Lakefront Studio Guest Home on Hermann Wine Trail!

Lakefront Studio Guest Home on Hermann Wine Trail!
New Haven
"Loved this property, very clean and well kept! Very pretty, lovely view. "
Lakefront Studio Guest Home on Hermann Wine Trail!
Vacation Home
A modern living room with a white sofa, a brown leather chair, a wooden staircase, and a flat-screen TV mounted on the wall.
A modern living room with a white sofa, a brown leather armchair, a small coffee table, and a chandelier.
A modern kitchen with green cabinets, stainless steel appliances, and a wooden dining table with chairs.
A bedroom with a large bed, a bench, a door, and a ceiling light.

Wine Country Getaway | JZ Vacation Rentals

Wine Country Getaway | JZ Vacation Rentals
Washington
"Great communication, had a couple of leaks and shower flooded but the maintenance came right away to fix it. Overall clean, AC/Heat unit in each room, big kitchen, wonderful sitting area and decor."
Wine Country Getaway | JZ Vacation Rentals
Cottage
A cozy cabin interior with a wooden ceiling, a large window with blinds, a sofa, a small table with a lamp, and a staircase.
A modern kitchen with dark cabinets, a central island, and a dining area with wooden chairs and a dark wooden table.
A log cabin with a green roof, a patio with outdoor furniture, and a stack of firewood in the foreground.
A wooden interior with a sloped ceiling, a staircase with a wooden railing, a sofa, and a desk with drawers.

Close to Vineyards: Updated New Haven Retreat!

Close to Vineyards: Updated New Haven Retreat!
New Haven
"Very clean and relaxing environment!! "
Close to Vineyards: Updated New Haven Retreat!
Apartment
A two-story building with a covered porch and a staircase leading to the upper level.
A covered outdoor patio with wooden flooring, metal chairs, tables, and ceiling fans.
A bedroom with a wooden headboard, a bed with a beige bedspread, a nightstand, and a dresser.

Near Wineries: Country Condo in Stony Hill

Near Wineries: Country Condo in Stony Hill
New Haven
"Clean and loved original architecture."
Near Wineries: Country Condo in Stony Hill
Apartment
A spacious living area with a dining table, chairs, a sofa, and a fireplace. There is a kitchen area with a refrigerator, stove, and cabinets. The room has large windows and a ceiling fan.
A kitchen with a vintage stove, modern sink, and a black refrigerator.
A large, two-story house with a balcony, surrounded by a grassy field and trees.
A bedroom with a large bed, a chair, a desk, and a view of the outdoors.

Lovely Couples Escape on Mississippi River!

Lovely Couples Escape on Mississippi River!
St. Charles
"Amazing place to stay, quiet and relaxing would definitely stay there again"
Lovely Couples Escape on Mississippi River!
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Stay near popular Northeast Missouri attractions

A baseball stadium with a large crowd, a prominent arch structure, and various advertisements.
Photo by Carl Guttovz

Busch Stadium

9.4/10 (4,850 reviews)
Catch an event at Busch Stadium during your trip to St. Louis. Experience the area's acclaimed art scene or attend a baseball game.
See properties
A bronze elephant sculpture with a pumpkin on its back, surrounded by greenery.
Photo by Jeff White

St. Louis Zoo

9.2/10 (4,367 reviews)
In the middle of St. Louis, meet the exotic and endangered animals that live in meticulously recreated ecosystems from all over the world.
See properties
A cityscape with a prominent statue in the center, surrounded by various buildings and a large stadium.

Enterprise Center

8.8/10 (1,597 reviews)
Catch an event at Enterprise Center during your trip to St. Louis. Experience the area's acclaimed art scene or attend a baseball game.
See properties
A cityscape with a prominent arch structure, various high-rise buildings, and a large government building.

Dome at America’s Center

8.4/10 (1,229 reviews)
Catch an event at Dome at America’s Center during your trip to St. Louis. Experience the area's great live music and fascinating museums.
See properties
A modern building with large glass windows, surrounded by a garden with red and pink tulips and purple flowers.

Forest Park

9.2/10 (3,389 reviews)
Nature, history and cultural institutions come together in one of the United States’ largest urban parks, which buzzes with St. Louis’ dynamic community spirit.
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A historic building with a large lawn, a flagpole with flags, and a clear blue sky.

St. Louis University

8.6/10 (526 reviews)
Explore the campus of St. Louis University as part of your travels around St. Louis. Wander around the area's picturesque gardens or experience its fascinating museums.
See properties
A tightrope walker balancing on a wire between buildings.

City Museum

9.0/10 (3,209 reviews)
This quirky children’s museum invites visitors to crawl through whales, climb into tree houses and whiz down three-story slides.
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America's Center Convention Complex

8.8/10 (306 reviews)
Learn about the events happening at America's Center Convention Complex during your trip to St. Louis. Experience the area's fascinating museums and acclaimed art scene.
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Learn more about Northeast Missouri

Great live music, sports teams, and popular sights from St. Louis Zoo to St. Louis Union Station—explore Northeast Missouri, a family-friendly destination also known for its theaters.

See all hotels in Northeast Missouri
A historic log cabin with a flagpole, hay bales, and autumn pumpkins.

Top Northeast Missouri Hotel Reviews

Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

10/10 Excellent
"Clean room, great staff, great location!"
Sam 1-night trip
Posted 1 hour ago
Clayton Plaza Hotel & Extended Stay
Pear Tree Inn St. Louis Near Union Station

Pear Tree Inn St. Louis Near Union Station

8/10 Good
"Room was clean and hotel was quiet and is in an easy and convenient area downtown."
Kathy 1-night trip
Posted 3 hours ago
Pear Tree Inn St. Louis Near Union Station
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

10/10 Excellent
"We stay every time we come down in a convenient area"
nichole 2-night trip
Posted 4 hours ago
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
Hollywood Casino & Hotel St. Louis

Hollywood Casino & Hotel St. Louis

8/10 Good
"Room was great and the bath was amazing. But the bed was very uncomfortable."
Kristina 2-night trip
Posted 12 hours ago
Hollywood Casino & Hotel St. Louis
Pear Tree Inn St. Louis Airport

Pear Tree Inn St. Louis Airport

10/10 Excellent
"I needed a place close to St Louis airport that was inexpensive clean, comfortable and safe. I got all of these things and will stay here again"
HEATHER 1-night trip
Posted 13 hours ago
Pear Tree Inn St. Louis Airport
Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

8/10 Good
"Neat niche property in the heart of downtown StL. Definitely not a luxury stay, but fun. Easy to get to"
Amanda 1-night trip
Posted 13 hours ago
Angad Arts Hotel St. Louis, Tapestry Collection by Hilton
Live by Loews - St.Louis

Live by Loews - St.Louis

10/10 Excellent
"Convenient, clean and a very tasty breakfast!"
Barbara 1-night trip
Posted 14 hours ago
Live by Loews - St.Louis
Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa

8/10 Good
"All went well room clean, staff outstanding"
Stephen 2-night trip
Posted 15 hours ago
Ameristar Casino Resort and Spa
Renaissance St. Louis Airport Hotel

Renaissance St. Louis Airport Hotel

8/10 Good
"The bartender was friendly. The place was clean and the food was excellent."
Joy 3-night trip
Posted 16 hours ago
Renaissance St. Louis Airport Hotel

More cheap stays in Northeast Missouri

Motel 6 Hazelwood, MO

Motel 6 Hazelwood, MO

5781 Campus Ct Hazelwood MO
$60 nightly
$73 total
Sep 7 - Sep 8
Total with taxes and fees
Motel 6 Hazelwood, MO
Days Inn and Suites by Wyndham St. Louis/Westport Plaza

Days Inn and Suites by Wyndham St. Louis/Westport Plaza

1970 Craig Rd Maryland Heights MO
$67 nightly
$78 total
Sep 14 - Sep 15
Total with taxes and fees
Days Inn and Suites by Wyndham St. Louis/Westport Plaza
Best Western St. Louis Inn

Best Western St. Louis Inn

6224 Heimos Industrial Park Dr St. Louis MO
$75 nightly
$86 total
Sep 17 - Sep 18
Total with taxes and fees
Best Western St. Louis Inn
Pear Tree Inn St. Louis Arnold

Pear Tree Inn St. Louis Arnold

1201 Drury Ln Arnold MO
$89 nightly
$102 total
Sep 14 - Sep 15
Total with taxes and fees
Pear Tree Inn St. Louis Arnold
Pear Tree Inn St. Louis Airport

Pear Tree Inn St. Louis Airport

10810 Pear Tree Ln St. Ann MO
$89 nightly
$104 total
Sep 14 - Sep 15
Total with taxes and fees
9.2/10 Wonderful! (3,209 reviews)
Pear Tree Inn St. Louis Airport
Tru By Hilton St. Louis Downtown

Tru By Hilton St. Louis Downtown

1221 Locus Street St. Louis MO
$98 nightly
$114 total
Sep 6 - Sep 7
Total with taxes and fees
Tru By Hilton St. Louis Downtown

Hotels in Northeast Missouri with star-rating

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