A large eye sculpture in a park surrounded by trees.

Find hotels in Northeast Missouri, MO from $72

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Our top choices for Northeast Missouri hotels

A living room with a sofa, coffee table, and patterned rug. There are large windows with blinds, a chandelier, and a view of the outside.
A building with a covered entrance, American flag, and a sign indicating it's open.
A hotel room with two beds, a television, a lamp, and a painting on the wall.
A dining area with multiple tables and chairs, a kitchen area with a refrigerator and various kitchen items, and a window with curtains.

1. FairBridge Inn Express, Monroe City

FairBridge Inn Express, Monroe City
Monroe City
United States
Patricia
$86 nightly
$93 total
Aug 23 - Aug 24
Total with taxes and fees
FairBridge Inn Express, Monroe City
A hotel room with a bed, a sofa, a desk, a chair, and a small table.
A hotel room with a bed, a desk with a computer, a chair, a TV, and a window with curtains.
A kitchenette with a coffee maker, toaster, microwave, and various kitchen utensils.
A bathroom with a sink, toilet, and bathtub. There is a towel rack with towels, a mirror, and a ceiling light.

2. Super 8 by Wyndham Macon

Super 8 by Wyndham Macon
Macon
United States
Austin
$81 nightly
$88 total
Aug 23 - Aug 24
Total with taxes and fees
Super 8 by Wyndham Macon
A compact kitchen with wooden cabinets, a coffee machine, and a dining area with metal chairs.
A hotel lobby with a black leather sofa, two bar stools, a reception desk, and a sign indicating no refund policy.
A compact kitchenette with a microwave, a small refrigerator, a coffee maker, and a telephone on a wooden dresser.
A neatly made bed with a brown quilted bedspread, a decorative pillow with a heart-shaped towel, and a bedside table with a lamp.

3. Americas Best Value Inn & Suites Macon at Sunset Dr

Americas Best Value Inn & Suites Macon at Sunset Dr
Macon
United States
William
$72 nightly
$77 total
Sep 5 - Sep 6
Total with taxes and fees
Americas Best Value Inn & Suites Macon at Sunset Dr
A hotel room with two beds, green walls, and artwork.
A room with a bed, a desk with a computer, a television, and a chair.
A hallway with a wooden door, a black refrigerator, and a microwave on top.
A laundry room with two washing machines, a dryer, and a wall-mounted heater.

4. Travelier Motel

Travelier Motel
Macon
United States
Jessica
$73 nightly
$79 total
Aug 22 - Aug 23
Total with taxes and fees
Travelier Motel
A neatly made bed with a white quilt, a dark wooden headboard, a bedside lamp, a red chair, and a wall decoration.
A hotel lobby with a Christmas tree, red sofas, a wooden reception desk, and a sign for Simple Rewards Inn.
A room with a large window, a red chair, and a wall-mounted air conditioner.
A building with a brick facade, a wooden door, and a neon 'OPEN' sign.

5. Simple Rewards Inn Shelbina

Simple Rewards Inn Shelbina
Shelbina
United States
Randy
$83 nightly
$91 total
Aug 23 - Aug 24
Total with taxes and fees
Simple Rewards Inn Shelbina
A wooden bridge with a rope railing in a forested area.
A modern kitchen with wooden cabinets, stainless steel appliances, and a large island.
A spacious living room with a high ceiling, wooden beams, a fireplace, and a dining area with a table and chairs.
A building with a covered porch, stone pillars, and a gravel driveway.

6. Lost Branch Lodge. Complete exterior remodel, spring 2026!

Lost Branch Lodge. Complete exterior remodel, spring 2026!
Brashear
United States
Megan K.
Lost Branch Lodge. Complete exterior remodel, spring 2026!
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Vacation Rentals in Northeast Missouri

Cabin
A park with a pond, picnic tables, and a gazebo.
A row of rustic, single-story buildings with a grassy lawn and picnic tables.
A grassy area with a picnic table and a dog.
A pool with a 5 FT depth marker.

Cannon Dam Cabins

Cannon Dam Cabins
Perry
"Cozy and well equipped with everything we may have needed"
Cannon Dam Cabins
Aparthotel
A compact living space with a sofa, a TV, a kitchen area with a fridge, microwave, and coffee maker, and a dining table.
A modern kitchen with a wooden island, bar stools, and a flat-screen TV.
A black building with large windows, a covered porch with a flag, and potted plants.
A compact kitchen with a marble backsplash, a refrigerator, a washing machine, and a dining area with chairs.

The Mercantile on the Katy Trail

The Mercantile on the Katy Trail
Hermann
"It’s an absolute must do! Such a cool little town right on the Katy Trail!"
The Mercantile on the Katy Trail
Aparthotel
A hotel room with a large bed, two bedside lamps, a modern bathroom, and a vibrant abstract painting on the wall.
A swimming pool with lounge chairs and a covered seating area.
A compact kitchen with white cabinets, a microwave, a coffee maker, and a sink.
A spacious bathroom with a large bathtub, a walk-in shower, and a vanity with a mirror.

Lighthouse Inn & Suites

Lighthouse Inn & Suites
Hannibal
"Wonderful place to stay!"
Lighthouse Inn & Suites
Apartment
A wooden deck with a rope fence, overlooking a lake and surrounded by trees.
A spacious living area with a sofa, a coffee table, and a dining table with a bench. There is a ceiling fan and a chandelier.
A kitchen with a large island, wooden cabinets, and a view of a lake.
A room with a large window, a microwave, a cabinet, and a sofa.

Lakefront Studio Guest Home on Hermann Wine Trail!

Lakefront Studio Guest Home on Hermann Wine Trail!
New Haven
"Loved this property, very clean and well kept! Very pretty, lovely view. "
Lakefront Studio Guest Home on Hermann Wine Trail!
Apartment
A spacious foyer with a grand staircase, a piano, and a large rug.
A spacious dining area with a round glass table, black metal chairs, and a wooden staircase leading to an upper level.
A spacious living room with a beige sofa, a dining area with a table and chairs, large windows, and a chandelier.
A backyard with a stone fire pit, two Adirondack chairs, and a hammock.

White House at Grand Central

White House at Grand Central
Grand Center
"Staff was great and accommodating to my needs."
White House at Grand Central
Apartment
A modern hotel lobby with a marble reception desk, a TV mounted on the wall, and a seating area with chairs and a sofa.
A modern living area with a grey sofa, a glass coffee table, and a black leather sofa. There are large windows and a visible interior space beyond.
A modern gym with treadmills, ellipticals, and weight machines. Large windows offer views of a swimming pool and greenery.
A modern living room with a pool table, a seating area, and a large window offering a view of the outdoors.

Landing Furnished Apartments - Central West End

Landing Furnished Apartments - Central West End
Central West End
"We booked a two bedroom for three people and the 2nd bedroom didn't have a bed! Contacted property, which was very responsive, but they couldn't do anything since we booked through Hotels. com"
Landing Furnished Apartments - Central West End
Apartment
A spacious room with a wooden dining table, chairs, a chandelier, and a bed with white bedding.
A spacious living area with a blue sofa, wooden flooring, and a chandelier.
A bedroom with a bed, a desk, a chair, a bench, and a ceiling fan.
A modern living room with a blue sofa, a coffee table, and a ceiling fan.

Spacious 3-Bedroom with King Bed

Spacious 3-Bedroom with King Bed
Central West End
"Clean room nice area "
Spacious 3-Bedroom with King Bed
Apartment
A modern bedroom with a large bed, a sofa, and a fireplace.
A spacious living room with a sofa, a coffee table, a fireplace, and a desk with a chair.
A spacious living room with a sectional sofa, a coffee table, and a fireplace. There are large windows and a high ceiling.

Hidden Gem | JZ Vacation Rentals

Hidden Gem | JZ Vacation Rentals
Central West End
Hidden Gem | JZ Vacation Rentals
Apartment
A two-story building with a covered porch and a staircase leading to the upper level.
A spacious living room with a wooden ceiling, a sofa, a dining table, and a kitchen area visible through an open doorway.
A bedroom with a wooden headboard, a bed with a beige bedspread, a nightstand, and a dresser.

Near Wineries: Country Condo in Stony Hill

Near Wineries: Country Condo in Stony Hill
New Haven
"Clean and loved original architecture."
Near Wineries: Country Condo in Stony Hill
Apartment
A living room with a sofa, armchair, and coffee table. There is a ceiling fan, a TV mounted on the wall, and a window with blinds.
A wooden deck with railings, a concrete foundation, and a view of a residential area with houses and trees.
A modern kitchen with dark cabinets, a black refrigerator, a white stove, and a wooden floor.
A bedroom with a bed, a TV, a ceiling fan, and a hallway leading to another room.

Walk to Carondelet Park: Quiet Couple's Getaway

Walk to Carondelet Park: Quiet Couple's Getaway
Carondelet
"We had a nice stay, close to things we wanted to do"
Walk to Carondelet Park: Quiet Couple's Getaway
Apartment
A red building with a sign for 'Catala House' and a 'Massage House' sign.
A red building with a balcony, a staircase, and outdoor seating with a blue umbrella.
A bedroom with a bed, a flat-screen TV mounted on the wall, a brick pillar, and a window with curtains.
A cozy loft-style living room with a brown leather sofa, a blue ottoman, and a patterned rug.

New Melle Apartment Near Missouri Wine Country

New Melle Apartment Near Missouri Wine Country
Wentzville
"Apartment was wonderful! Very spacious and lots of furniture. Had a flat screen in the living room and bedroom that included Netflix and Prime. Air conditioner worked very well. Was very quiet and in a good location. Property manager was very friendly. There was even a very nice tea selection included with our stay. All amenities including, fridge, sinks, countertop burner, shower, washer, dryer, and toilet worked with no issues. All the dishes and mugs were clean. Plenty of towels to use during...
New Melle Apartment Near Missouri Wine Country
Cottage
A modern kitchen with stainless steel appliances, a large island, and leather chairs.
A living room with a beige sofa, a round ottoman, a fireplace, and a chandelier.
A dining room with a wooden table, green chairs, a chandelier, and a fireplace.
A hallway with a staircase, a white sofa, a plant, and a chandelier.

Home 2 Mi to Dtwn St Louis: Great for Families!

Home 2 Mi to Dtwn St Louis: Great for Families!
Lafayette Square
"Clean space with so much character!"
Home 2 Mi to Dtwn St Louis: Great for Families!
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Stay near popular Northeast Missouri attractions

A baseball stadium with a large crowd, a prominent arch structure, and various advertisements.
Photo by Carl Guttovz

Busch Stadium

9.4/10 (4,850 reviews)
Catch an event at Busch Stadium during your trip to St. Louis. Experience the area's acclaimed art scene or attend a baseball game.
See properties
A bronze elephant sculpture with a pumpkin on its back, surrounded by greenery.
Photo by Jeff White

St. Louis Zoo

9.2/10 (4,367 reviews)
In the middle of St. Louis, meet the exotic and endangered animals that live in meticulously recreated ecosystems from all over the world.
See properties
A cityscape with a prominent statue in the center, surrounded by various buildings and a large stadium.

Enterprise Center

8.8/10 (1,597 reviews)
Catch an event at Enterprise Center during your trip to St. Louis. Experience the area's acclaimed art scene or attend a baseball game.
See properties
A cityscape with a prominent arch structure, various high-rise buildings, and a large government building.

Dome at America’s Center

8.4/10 (1,229 reviews)
Catch an event at Dome at America’s Center during your trip to St. Louis. Experience the area's great live music and fascinating museums.
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A modern building with large glass windows, surrounded by a garden with red and pink tulips and purple flowers.

Forest Park

9.2/10 (3,389 reviews)
Nature, history and cultural institutions come together in one of the United States’ largest urban parks, which buzzes with St. Louis’ dynamic community spirit.
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A tightrope walker balancing on a wire between buildings.

City Museum

9.0/10 (3,209 reviews)
This quirky children’s museum invites visitors to crawl through whales, climb into tree houses and whiz down three-story slides.
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A historic building with a large lawn, a flagpole with flags, and a clear blue sky.

St. Louis University

8.6/10 (526 reviews)
Explore the campus of St. Louis University as part of your travels around St. Louis. Wander around the area's picturesque gardens or experience its fascinating museums.
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America's Center Convention Complex

8.8/10 (306 reviews)
Learn about the events happening at America's Center Convention Complex during your trip to St. Louis. Experience the area's fascinating museums and acclaimed art scene.
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Learn more about Northeast Missouri

Great live music, sports teams, and popular sights from St. Louis Zoo to St. Louis Union Station—explore Northeast Missouri, a family-friendly destination also known for its theaters.

See all hotels in Northeast Missouri
A historic log cabin with a flagpole, hay bales, and autumn pumpkins.

Top Northeast Missouri Hotel Reviews

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

10/10 Excellent
"Loved the beautiful old hotel,rooms were big,clean,and we'll maintained. Only 4 or so blocks from ballpark."
Jerri 2-night trip
Posted 2 hours ago
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
Pear Tree Inn St. Louis Airport

Pear Tree Inn St. Louis Airport

10/10 Excellent
"Na"
DAVID 1-night trip
Posted 16 hours ago
Pear Tree Inn St. Louis Airport
Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

10/10 Excellent
"Nice up to date room. I especially liked the reading lights attached to the bed. Very convenient location. Nice selections for breakfast. We were surprised by the city's overnight road resurfacing, but it didn't keep us awake."
Susan 3-night trip
Posted 16 hours ago
Clayton Plaza Hotel & Extended Stay
The Royal Sonesta Chase Park Plaza St. Louis

The Royal Sonesta Chase Park Plaza St. Louis

8/10 Good
"staff excellent, friendly and very helpful"
donald 1-night trip
Posted 17 hours ago
The Royal Sonesta Chase Park Plaza St. Louis
Moonrise Hotel

Moonrise Hotel

8/10 Good
"Loved the hotel. The only downside was the street noise from midnight-3 am even on the 7th floor. Nothing the hotel could have done as there were a bunch of people on the street."
Piyush 1-night trip
Posted 20 hours ago
Moonrise Hotel
Home2 Suites by Hilton St. Louis Downtown

Home2 Suites by Hilton St. Louis Downtown

8/10 Good
"Clean room, staff was great- parking was expensive!"
Peter 1-night trip
Posted 3 days ago
Home2 Suites by Hilton St. Louis Downtown

More cheap stays in Northeast Missouri

Motel 6 Hazelwood, MO

Motel 6 Hazelwood, MO

5781 Campus Ct Hazelwood MO
$59 nightly
$72 total
Sep 1 - Sep 2
Total with taxes and fees
8.4/10 Very Good! (2,166 reviews)
Motel 6 Hazelwood, MO
Best Western St. Louis Inn

Best Western St. Louis Inn

6224 Heimos Industrial Park Dr St. Louis MO
$68 nightly
$78 total
Aug 30 - Aug 31
Total with taxes and fees
Best Western St. Louis Inn
Days Inn and Suites by Wyndham St. Louis/Westport Plaza

Days Inn and Suites by Wyndham St. Louis/Westport Plaza

1970 Craig Rd Maryland Heights MO
$68 nightly
$79 total
Aug 24 - Aug 25
Total with taxes and fees
4.4/10 (1,004 reviews)
Days Inn and Suites by Wyndham St. Louis/Westport Plaza
Pear Tree Inn St. Louis Arnold

Pear Tree Inn St. Louis Arnold

1201 Drury Ln Arnold MO
$89 nightly
$103 total
Sep 1 - Sep 2
Total with taxes and fees
Pear Tree Inn St. Louis Arnold
Tru By Hilton St. Louis Downtown

Tru By Hilton St. Louis Downtown

1221 Locus Street St. Louis MO
$89 nightly
$105 total
Aug 30 - Aug 31
Total with taxes and fees
7.8/10 Good! (934 reviews)
Tru By Hilton St. Louis Downtown
Pear Tree Inn St. Louis Airport

Pear Tree Inn St. Louis Airport

10810 Pear Tree Ln St. Ann MO
$90 nightly
$106 total
Aug 26 - Aug 27
Total with taxes and fees
9.2/10 Wonderful! (3,177 reviews)
Pear Tree Inn St. Louis Airport

Hotels in Northeast Missouri with star-rating

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