Title: Top 10 Hotels in Northeast Missouri from $67 - Competitive Prices | Expedia.com [Northeast Missouri Travel Guide](https://expedia.com/Northeast-Missouri.dx6058818)[Vacation Rentals in Northeast Missouri](https://expedia.com/Northeast-Missouri-Vacation-Rentals.d6058818.Travel-Guide-VacationRentals)[Flights to Northeast Missouri](https://expedia.com/Cheap-Flights-To-Northeast-Missouri.d6058818.Travel-Guide-Flights)[Things to do in Northeast Missouri](https://expedia.com/Things-To-Do-In-Northeast-Missouri.d6058818.Travel-Guide-Activities)[Car Rentals in Northeast Missouri](https://expedia.com/Car-Rentals-In-Northeast-Missouri.d6058818.Car-Rental-Guide)[Northeast Missouri Vacation Packages](https://expedia.com/Northeast-Missouri.d6058818.Destination-Travel-Guides) ![Grant\'s Farm which includes heritage architecture](https://images.trvl-media.com/place/6069377/88294c82-c384-49b1-b936-14bc595df677.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/6069377/88294c82-c384-49b1-b936-14bc595df677.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Upfront pricing Our total price for your stay includes taxes and fees - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save 10% or more on over 100,000 hotels worldwide with Member Prices [Learn about One Key](https://www.expedia.com/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Go beyond your typical stay in Northeast Missouri Cabins [](https://www.expedia.com/Hotel-Search?destination=Northeast+Missouri%2C+Missouri%2C+United+States+of+America®ionId=6058818&latLong=39.356223%2C-91.587801&adults=2&startDate=2026-03-12&d1=2026-03-12&endDate=2026-03-14&d2=2026-03-14&lodging=CABIN) Pet-friendly [](https://www.expedia.com/Hotel-Search?destination=Northeast+Missouri%2C+Missouri%2C+United+States+of+America®ionId=6058818&latLong=39.356223%2C-91.587801&adults=2&startDate=2026-03-12&d1=2026-03-12&endDate=2026-03-14&d2=2026-03-14&amenities=PETS) Pool [](https://www.expedia.com/Hotel-Search?destination=Northeast+Missouri%2C+Missouri%2C+United+States+of+America®ionId=6058818&latLong=39.356223%2C-91.587801&adults=2&startDate=2026-03-12&d1=2026-03-12&endDate=2026-03-14&d2=2026-03-14&amenities=POOL) Hot tub [](https://www.expedia.com/Hotel-Search?destination=Northeast+Missouri%2C+Missouri%2C+United+States+of+America®ionId=6058818&latLong=39.356223%2C-91.587801&adults=2&startDate=2026-03-12&d1=2026-03-12&endDate=2026-03-14&d2=2026-03-14&amenities=HOT_TUB) Spa [](https://www.expedia.com/Hotel-Search?destination=Northeast+Missouri%2C+Missouri%2C+United+States+of+America®ionId=6058818&latLong=39.356223%2C-91.587801&adults=2&startDate=2026-03-12&d1=2026-03-12&endDate=2026-03-14&d2=2026-03-14&amenities=SPA_ON_SITE) Great for families [](https://www.expedia.com/Hotel-Search?destination=Northeast+Missouri%2C+Missouri%2C+United+States+of+America®ionId=6058818&latLong=39.356223%2C-91.587801&adults=2&startDate=2026-03-12&d1=2026-03-12&endDate=2026-03-14&d2=2026-03-14&travelerType=family_friendly) Waterpark [](https://www.expedia.com/Hotel-Search?destination=Northeast+Missouri%2C+Missouri%2C+United+States+of+America®ionId=6058818&latLong=39.356223%2C-91.587801&adults=2&startDate=2026-03-12&d1=2026-03-12&endDate=2026-03-14&d2=2026-03-14&amenities=WATER_PARK) Apart hotel [](https://www.expedia.com/Hotel-Search?destination=Northeast+Missouri%2C+Missouri%2C+United+States+of+America®ionId=6058818&latLong=39.356223%2C-91.587801&adults=2&startDate=2026-03-12&d1=2026-03-12&endDate=2026-03-14&d2=2026-03-14&lodging=APART_HOTEL) Farm [](https://www.expedia.com/Hotel-Search?destination=Northeast+Missouri%2C+Missouri%2C+United+States+of+America®ionId=6058818&latLong=39.356223%2C-91.587801&adults=2&startDate=2026-03-12&d1=2026-03-12&endDate=2026-03-14&d2=2026-03-14&lodging=AGRITOURISM) Cottages [](https://www.expedia.com/Hotel-Search?destination=Northeast+Missouri%2C+Missouri%2C+United+States+of+America®ionId=6058818&latLong=39.356223%2C-91.587801&adults=2&startDate=2026-03-12&d1=2026-03-12&endDate=2026-03-14&d2=2026-03-14&lodging=COTTAGE) Apart­ment [](https://www.expedia.com/Hotel-Search?destination=Northeast+Missouri%2C+Missouri%2C+United+States+of+America®ionId=6058818&latLong=39.356223%2C-91.587801&adults=2&startDate=2026-03-12&d1=2026-03-12&endDate=2026-03-14&d2=2026-03-14&lodging=APARTMENT) ## Check prices for these dates Tonight [Feb 26 - Feb 27](https://www.expedia.com/Hotel-Search?regionId=6058818&startDate=2026-02-26&endDate=2026-02-27&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Feb 27 - Feb 28](https://www.expedia.com/Hotel-Search?regionId=6058818&startDate=2026-02-27&endDate=2026-02-28&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Feb 27 - Mar 1](https://www.expedia.com/Hotel-Search?regionId=6058818&startDate=2026-02-27&endDate=2026-03-01&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Mar 6 - Mar 8](https://www.expedia.com/Hotel-Search?regionId=6058818&startDate=2026-03-06&endDate=2026-03-08&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Northeast Missouri hotels ![Club Suite, 1 King Bed, Hot Tub | Private spa tub](https://images.trvl-media.com/lodging/2000000/1170000/1161500/1161498/867338f3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/2000000/1170000/1161500/1161498/a9bed2f7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/2000000/1170000/1161500/1161498/a348d8f1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1170000/1161500/1161498/90bd94d1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Pinemark Inn & Suites [](https://www.expedia.com/St-Clair-Hotels-Pinemark-Inn-Suites.h1161498.Hotel-Information) St. Clair 9.6/10 Exceptional (1,002 reviews) "The room is always spotless and the staff is always very friendly. The heat lamp in the bathroom is one of y favorite features. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sydney $121 nightly $132 total Mar 1 - Mar 2 Total with taxes and fees [](https://www.expedia.com/St-Clair-Hotels-Pinemark-Inn-Suites.h1161498.Hotel-Information) ![Indoor pool](https://images.trvl-media.com/lodging/2000000/1800000/1790900/1790806/6c9e28fd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pillowtop beds, minibar, desk, soundproofing](https://images.trvl-media.com/lodging/2000000/1800000/1790900/1790806/44eec777.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pillowtop beds, minibar, desk, soundproofing](https://images.trvl-media.com/lodging/2000000/1800000/1790900/1790806/0bdc571d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1800000/1790900/1790806/de075f26.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Depot Inn and Suites [](https://www.expedia.com/La-Plata-Hotels-Depot-Inn-And-Suites.h1790806.Hotel-Information) La Plata 9.8/10 Exceptional (636 reviews) "A very pleasant surprise, wonderful decor." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Michael $80 nightly $87 total Mar 29 - Mar 30 Total with taxes and fees [](https://www.expedia.com/La-Plata-Hotels-Depot-Inn-And-Suites.h1790806.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/460000/459500/459418/ff1a33b3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/460000/459500/459418/0e791573.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/460000/459500/459418/9a9e921d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Studio Suite, 1 King Bed, Non Smoking | In-room safe, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/460000/459500/459418/6adb4ce9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham Washington [](https://www.expedia.com/Washington-Hotels-Super-8-By-Wyndham-Washington.h459418.Hotel-Information) Washington 8.4/10 Very Good (707 reviews) "The staff was extremely nice & accommodating." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Brenda $83 nightly $94 total Mar 24 - Mar 25 Total with taxes and fees [](https://www.expedia.com/Washington-Hotels-Super-8-By-Wyndham-Washington.h459418.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/2000000/1080000/1077200/1077183/3a1e3bea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/2000000/1080000/1077200/1077183/d4f404b7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free full breakfast](https://images.trvl-media.com/lodging/2000000/1080000/1077200/1077183/70eb43b7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1080000/1077200/1077183/d2118181.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Plus Washington Hotel [](https://www.expedia.com/Washington-Hotels-Best-Western-Plus-Washington-Hotel.h1077183.Hotel-Information) Washington 9.2/10 Wonderful (662 reviews) "Clean room and hotel with a nice breakfast, have stayed here two times while visiting family." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Brooks $129 nightly $147 total Mar 1 - Mar 2 Total with taxes and fees [](https://www.expedia.com/Washington-Hotels-Best-Western-Plus-Washington-Hotel.h1077183.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/12000000/11310000/11309000/11308942/863ee254.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/12000000/11310000/11309000/11308942/f63d6bd9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed with Sofa bed | Desk, iron/ironing board, free cribs/infant beds, free WiFi](https://images.trvl-media.com/lodging/12000000/11310000/11309000/11308942/5a40455a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/12000000/11310000/11309000/11308942/5c0eb04d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sleep Inn & Suites Hannibal West [](https://www.expedia.com/Hannibal-Hotels-Sleep-Inn-Suites.h11308942.Hotel-Information) Hannibal 9.6/10 Exceptional (1,001 reviews) "It was a good midway stop for us on our way to Memphis." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Joel $107 nightly $124 total Mar 8 - Mar 9 Total with taxes and fees [](https://www.expedia.com/Hannibal-Hotels-Sleep-Inn-Suites.h11308942.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/990000/983700/983646/4e0fe2c3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, iron/ironing board, free cribs/infant beds, rollaway beds](https://images.trvl-media.com/lodging/1000000/990000/983700/983646/79af7d21.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/990000/983700/983646/12a7ffe8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, sun loungers](https://images.trvl-media.com/lodging/1000000/990000/983700/983646/7d037912.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn & Suites Hannibal West [](https://www.expedia.com/Hannibal-Hotels-Quality-Inn-Suites-Hannibal.h983646.Hotel-Information) Hannibal 8.0/10 Very Good (1,014 reviews) "Good breakfast selections. Close to a good restaurant. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Steve $73 nightly $84 total Mar 16 - Mar 17 Total with taxes and fees [](https://www.expedia.com/Hannibal-Hotels-Quality-Inn-Suites-Hannibal.h983646.Hotel-Information) ![Desk, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/20000/16300/16249/d6669a71.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/16300/16249/ba8e13b0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, seasonal outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/1000000/20000/16300/16249/b520e740.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, seasonal outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/1000000/20000/16300/16249/74fd9989.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western On The River [](https://www.expedia.com/Hannibal-Hotels-Best-Western-On-The-River.h16249.Hotel-Information) Hannibal 8.6/10 Excellent (1,003 reviews) "Everything was great. Will definitely stay again." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ethan $65 nightly $74 total Feb 28 - Mar 1 Total with taxes and fees [](https://www.expedia.com/Hannibal-Hotels-Best-Western-On-The-River.h16249.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/36000000/35850000/35848800/35848753/d38dcff4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/36000000/35850000/35848800/35848753/da587b35.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/36000000/35850000/35848800/35848753/50b5788d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/36000000/35850000/35848800/35848753/660bdaf5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express & Suites Wentzville St Louis West by IHG [](https://www.expedia.com/St-Louis-Hotels-Holiday-Inn-Express-Suites-Wentzville-St-Louis-West.h35848753.Hotel-Information) Wentzville 9.4/10 Exceptional (872 reviews) "Beautiful hotel, friendly staff, good breakfast." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Erika $135 nightly $161 total Mar 1 - Mar 2 Total with taxes and fees [](https://www.expedia.com/St-Louis-Hotels-Holiday-Inn-Express-Suites-Wentzville-St-Louis-West.h35848753.Hotel-Information) ![Free daily English breakfast](https://images.trvl-media.com/lodging/111000000/110500000/110496100/110496029/d4056513.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Luxury Suite, 1 King Bed with Sofa bed, Kitchenette | Living area | 55-inch Smart TV with cable channels](https://images.trvl-media.com/lodging/111000000/110500000/110496100/110496029/737d5070.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Family Suite, Multiple Beds | Premium bedding, desk, laptop workspace, iron/ironing board](https://images.trvl-media.com/lodging/111000000/110500000/110496100/110496029/4fe3b63f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/111000000/110500000/110496100/110496029/8a16fcd2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Heritage Hotel Quincy [](https://www.expedia.com/Quincy-Hotels-Heritage-Hotel-Quincy.h110496029.Hotel-Information) Quincy 8.8/10 Excellent (306 reviews) "Great hotel clean and quiet " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Danielle $64 nightly $73 total Mar 25 - Mar 26 Total with taxes and fees [](https://www.expedia.com/Quincy-Hotels-Heritage-Hotel-Quincy.h110496029.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/670000/664500/664414/6093d918.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/670000/664500/664414/b493e570.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/670000/664500/664414/897465ee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/670000/664500/664414/159a98ff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Suites St Charles - St Louis [](https://www.expedia.com/St-Louis-Hotels-Comfort-Suites-St-Charles-St-Louis.h664414.Hotel-Information) St. Charles 8.4/10 Very Good (1,000 reviews) "Great hotel for the money" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jere $92 nightly $105 total Mar 5 - Mar 6 Total with taxes and fees [](https://www.expedia.com/St-Louis-Hotels-Comfort-Suites-St-Charles-St-Louis.h664414.Hotel-Information) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/130000/123600/123590/fd2e50c6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/130000/123600/123590/9c660a01.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/130000/123600/123590/08bb1016.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Double Beds, Non Smoking | Pillowtop beds, desk, blackout drapes, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/130000/123600/123590/adba1fe4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham Kirksville-University Area [](https://www.expedia.com/Macon-Hotels-Country-Club-Inn-Suites.h123590.Hotel-Information) Kirksville 9.2/10 Wonderful (174 reviews) "Great breakfast let me check in early was very nice " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jamie $60 nightly $67 total Mar 1 - Mar 2 Total with taxes and fees [](https://www.expedia.com/Macon-Hotels-Country-Club-Inn-Suites.h123590.Hotel-Information) ![Indoor spa tub](https://images.trvl-media.com/lodging/2000000/1150000/1145000/1144935/89328cf1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/2000000/1150000/1145000/1144935/ea8f8767.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pub](https://images.trvl-media.com/lodging/2000000/1150000/1145000/1144935/9342c79e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/2000000/1150000/1145000/1144935/00bdd6be.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Stoney Creek Inn Quincy [](https://www.expedia.com/Quincy-Hotels-Stoney-Creek-Inn-Quincy.h1144935.Hotel-Information) Quincy 8.8/10 Excellent (1,001 reviews) "Easy check-in, clean room, great bathroom. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Donetta S $144 nightly $164 total Mar 1 - Mar 2 Total with taxes and fees [](https://www.expedia.com/Quincy-Hotels-Stoney-Creek-Inn-Quincy.h1144935.Hotel-Information) ![Premium bedding, desk, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/10000/800/704/12181f11.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pool](https://images.trvl-media.com/lodging/1000000/10000/800/704/557cf01e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Coffee service](https://images.trvl-media.com/lodging/1000000/10000/800/704/79b70294.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/800/704/7090af8c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham St Charles [](https://www.expedia.com/St-Louis-Hotels-Super-8-By-Wyndham-St-Charles.h704.Hotel-Information) St. Charles 8.0/10 Very Good (1,000 reviews) "Great place to stay for the $$$" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kale $84 nightly $97 total Mar 5 - Mar 6 Total with taxes and fees [](https://www.expedia.com/St-Louis-Hotels-Super-8-By-Wyndham-St-Charles.h704.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/2000000/1340000/1330400/1330309/001d26f2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1340000/1330400/1330309/254f5b60.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/2000000/1340000/1330400/1330309/0036679a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/2000000/1340000/1330400/1330309/ad6cce96.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Country Inn & Suites by Radisson, St. Charles Historic District [](https://www.expedia.com/St-Louis-Hotels-Country-Inn-Suites-By-Radisson.h1330309.Hotel-Information) St. Charles Historic District 9.4/10 Exceptional (1,002 reviews) "Wonderful place staff awesome " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Chad $114 nightly $131 total Mar 29 - Mar 30 Total with taxes and fees [](https://www.expedia.com/St-Louis-Hotels-Country-Inn-Suites-By-Radisson.h1330309.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/18000000/17400000/17395600/17395579/d446d190.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/18000000/17400000/17395600/17395579/1d29e551.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/18000000/17400000/17395600/17395579/9950450a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/18000000/17400000/17395600/17395579/b52a585e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn St. Louis Wentzville [](https://www.expedia.com/St-Louis-Hotels-Hampton-Inn-By-Hilton-Wentzville.h17395579.Hotel-Information) Wentzville 9.0/10 Wonderful (664 reviews) "Prompt service, quick check in. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Emily $130 nightly $148 total Mar 8 - Mar 9 Total with taxes and fees [](https://www.expedia.com/St-Louis-Hotels-Hampton-Inn-By-Hilton-Wentzville.h17395579.Hotel-Information) ![Dining](https://images.trvl-media.com/lodging/1000000/30000/20500/20482/8a5baebb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Queen Beds, Non Smoking | Down comforters, pillowtop beds, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/30000/20500/20482/7d76c669.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/1000000/30000/20500/20482/b08ddc86.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/20500/20482/w1021h682x0y0-c9b85e2f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn Kirksville [](https://www.expedia.com/Macon-Hotels-Quality-Inn-Kirksville.h20482.Hotel-Information) Kirksville 7.6/10 Good (396 reviews) "The staff was friendly and provided excellent service!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Don $65 nightly $73 total Mar 1 - Mar 2 Total with taxes and fees [](https://www.expedia.com/Macon-Hotels-Quality-Inn-Kirksville.h20482.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/41500/41453/68bc6d17.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/41500/41453/0c7d61f8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/50000/41500/41453/c689fe3d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, blackout drapes, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/50000/41500/41453/141b0a99.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Drury Inn & Suites St. Louis St. Peters [](https://www.expedia.com/St-Louis-Hotels-Drury-Inn-Suites-St-Louis-St-Peters.h41453.Hotel-Information) St. Peters 9.4/10 Exceptional (1,002 reviews) "Comfortable room. Quiet even though next to interstate. Excellent food " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Geo $110 nightly $126 total Mar 3 - Mar 4 Total with taxes and fees [](https://www.expedia.com/St-Louis-Hotels-Drury-Inn-Suites-St-Louis-St-Peters.h41453.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/43000000/42200000/42192300/42192228/48a8d8cb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/43000000/42200000/42192300/42192228/9683af6c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/43000000/42200000/42192300/42192228/327f0415.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/43000000/42200000/42192300/42192228/c962b0fb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express & Suites St Peters by IHG [](https://www.expedia.com/St-Louis-Hotels-Holiday-Inn-Express-Suites-St-Peters.h42192228.Hotel-Information) St. Peters 9.4/10 Exceptional (393 reviews) "Parking was easy and the room was nice." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Martha $111 nightly $129 total Mar 1 - Mar 2 Total with taxes and fees [](https://www.expedia.com/St-Louis-Hotels-Holiday-Inn-Express-Suites-St-Peters.h42192228.Hotel-Information) ![Meeting facility](https://images.trvl-media.com/lodging/119000000/118200000/118192700/118192676/a2892e05.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Family House | Premium bedding, free WiFi, bed sheets](https://images.trvl-media.com/lodging/119000000/118200000/118192700/118192676/753bab7d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/119000000/118200000/118192700/118192676/56fd11a2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Cottage | Living area](https://images.trvl-media.com/lodging/119000000/118200000/118192700/118192676/w950h640x10y0-79d0486f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Inns at St. Albans [](https://www.expedia.com/Saint-Albans-Hotels-Inns-At-St-Albans.h118192676.Hotel-Information) Saint Albans 10/10 Exceptional (3 reviews) "Great little peaceful getaway for the weekend. Not a lot of food options nearby so you need to plan ahead, but really enjoyed our stay." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Paul $226 nightly $242 total Mar 1 - Mar 2 Total with taxes and fees [](https://www.expedia.com/Saint-Albans-Hotels-Inns-At-St-Albans.h118192676.Hotel-Information) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/970000/969900/969831/28678ee3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/970000/969900/969831/7111328b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free buffet breakfast](https://images.trvl-media.com/lodging/1000000/970000/969900/969831/e705e06d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Queen Beds, Non Smoking | Desk, laptop workspace, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/970000/969900/969831/0bffe90f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn Near Six Flags St. Louis [](https://www.expedia.com/Pacific-Hotels-Comfort-Inn-Near-Six-Flags-St-Louis.h969831.Hotel-Information) Pacific 8.4/10 Very Good (895 reviews) "I loved that the hotel is conveniently located very close to the exit off the highway. The staff was pleasant. The rooms have been upgraded, the bed was very comfortable and overall the hotel is very clean." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ron $93 nightly $106 total Mar 16 - Mar 17 Total with taxes and fees [](https://www.expedia.com/Pacific-Hotels-Comfort-Inn-Near-Six-Flags-St-Louis.h969831.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.com/Hotel-Search?startDate=2026-03-12&endDate=2026-03-13®ionId=6058818&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-us-ca.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## The Annual Vacation Sale Members save up to 40% on hotels and homes. Plan this year’s big trip and save. [Book now](https://expedia.com/deals?rfrr=HTG_SPRING_PROMO_6058818) ## Vacation Rentals in Northeast Missouri Cabin ![Free WiFi, bed sheets](https://images.trvl-media.com/lodging/112000000/111250000/111246500/111246418/4edef455.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/112000000/111250000/111246500/111246418/8888df33.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free WiFi, bed sheets](https://images.trvl-media.com/lodging/112000000/111250000/111246500/111246418/29095ef4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free WiFi, bed sheets](https://images.trvl-media.com/lodging/112000000/111250000/111246500/111246418/29cf23f6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cannon Dam Cabins [](https://www.expedia.com/Perry-Hotels-Cannon-Dam-Cabins.h111246418.Hotel-Information) Perry 9.2/10 Wonderful (15 reviews) "management great, cabins very comfortable and roomy, good location" [](https://www.expedia.com/Perry-Hotels-Cannon-Dam-Cabins.h111246418.Hotel-Information) Apartment ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/116000000/115640000/115639500/115639446/7532679b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/116000000/115640000/115639500/115639446/e600320b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2 Bedrooms) | Front of property](https://images.trvl-media.com/lodging/116000000/115640000/115639500/115639446/4b36817f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/116000000/115640000/115639500/115639446/4ff9a054.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Near Wineries: Country Condo in New Haven [](https://www.expedia.com/New-Haven-Hotels-Near-Vineyards-Country-Condo-In-New-Haven.h115639446.Hotel-Information) New Haven 10/10 Exceptional (1 review) "Clean and loved original architecture." [](https://www.expedia.com/New-Haven-Hotels-Near-Vineyards-Country-Condo-In-New-Haven.h115639446.Hotel-Information) Aparthotel ![Down comforters, blackout drapes, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/106000000/105130000/105120300/105120258/0ce65e62.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/106000000/105130000/105120300/105120258/d6514417.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Suite | Living area | Smart TV, streaming services](https://images.trvl-media.com/lodging/106000000/105130000/105120300/105120258/1abb1816.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pool](https://images.trvl-media.com/lodging/106000000/105130000/105120300/105120258/4063c21a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Lighthouse Inn & Suites [](https://www.expedia.com/Hannibal-Hotels-Lighthouse-Inn-Suites.h105120258.Hotel-Information) Hannibal 8.8/10 Excellent (25 reviews) "Nice room. Matched the pictures. Exactly what we were looking for." [](https://www.expedia.com/Hannibal-Hotels-Lighthouse-Inn-Suites.h105120258.Hotel-Information) Aparthotel ![Comfort Loft, 2 Queen Beds, Bathtub, Garden View | Living area | 45-inch Smart TV with digital channels, books, streaming services](https://images.trvl-media.com/lodging/104000000/103390000/103386000/103385931/2e86baed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/104000000/103390000/103386000/103385931/127f3fbe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Romantic Loft, 1 King Bed, Non Smoking, Bathtub | Private kitchen | Full-size fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/104000000/103390000/103386000/103385931/9b3112da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Comfort Loft, 2 Queen Beds, Bathtub, Garden View | In-room dining](https://images.trvl-media.com/lodging/104000000/103390000/103386000/103385931/b543c998.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Mercantile on the Katy Trail [](https://www.expedia.com/Hermann-Hotels-The-Mercantile-On-The-Katy-Trail.h103385931.Hotel-Information) Hermann 9.8/10 Exceptional (28 reviews) "Great place, fully stocked and clean!" [](https://www.expedia.com/Hermann-Hotels-The-Mercantile-On-The-Katy-Trail.h103385931.Hotel-Information) Vacation Home ![Living area](https://images.trvl-media.com/lodging/100000000/99340000/99335800/99335731/8dcec7f0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/100000000/99340000/99335800/99335731/c8cfaaff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Living area](https://images.trvl-media.com/lodging/100000000/99340000/99335800/99335731/413f9d12.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House, Multiple Beds, Patio, City View | Private kitchen | Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/100000000/99340000/99335800/99335731/daecc64b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Wine Country Getaway | JZ Vacation Rentals [](https://www.expedia.com/Washington-Hotels-Stylish-Home-Near-Wine-Country-JZ-Vacation-Rentals.h99335731.Hotel-Information) Washington 8.0/10 Very Good (1 review) "Great communication, had a couple of leaks and shower flooded but the maintenance came right away to fix it. Overall clean, AC/Heat unit in each room, big kitchen, wonderful sitting area and decor." [](https://www.expedia.com/Washington-Hotels-Stylish-Home-Near-Wine-Country-JZ-Vacation-Rentals.h99335731.Hotel-Information) Apartment ![Lobby](https://images.trvl-media.com/lodging/84000000/83130000/83121100/83121050/f3c125ad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Apartment | Interior entrance](https://images.trvl-media.com/lodging/84000000/83130000/83121100/83121050/55f5dbb9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![BBQ/picnic area](https://images.trvl-media.com/lodging/84000000/83130000/83121100/83121050/0bbeb61f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Comfort Apartment | Living area | 42-inch Smart TV with digital channels, TV, Netflix](https://images.trvl-media.com/lodging/84000000/83130000/83121100/83121050/4a627d76.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### White House at Grand Central [](https://www.expedia.com/St-Louis-Hotels-Grand-Center-Apartments.h83121050.Hotel-Information) Grand Center 8.4/10 Very Good (127 reviews) "Very clean and very friendly people " [](https://www.expedia.com/St-Louis-Hotels-Grand-Center-Apartments.h83121050.Hotel-Information) Apartment ![Apartment (0 Bedroom) | Interior](https://images.trvl-media.com/lodging/94000000/93200000/93198800/93198755/9f8814d0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (0 Bedroom) | Interior](https://images.trvl-media.com/lodging/94000000/93200000/93198800/93198755/ada5d4be.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (0 Bedroom) | Interior](https://images.trvl-media.com/lodging/94000000/93200000/93198800/93198755/15ce84b2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (0 Bedroom) | Interior](https://images.trvl-media.com/lodging/94000000/93200000/93198800/93198755/b3a8116c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Lakefront Studio Guest Home on Hermann Wine Trail! [](https://www.expedia.com/New-Haven-Hotels-Lakefront-Studio-Guest-Home-On-Hermann-Wine-Trail.h93198755.Hotel-Information) New Haven 10/10 Exceptional (3 reviews) "Loved this property, very clean and well kept! Very pretty, lovely view. " [](https://www.expedia.com/New-Haven-Hotels-Lakefront-Studio-Guest-Home-On-Hermann-Wine-Trail.h93198755.Hotel-Information) Cottage ![House (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/94000000/93550000/93546000/93545930/5c5a75bf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/94000000/93550000/93546000/93545930/1b94771c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (2 Bedrooms) | Front of property](https://images.trvl-media.com/lodging/94000000/93550000/93546000/93545930/4c282423.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/94000000/93550000/93546000/93545930/c859cadc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Peaceful Guest Home w/ Patio on 152-acre Farm [](https://www.expedia.com/Berger-Hotels-Peaceful-Guest-Home-W-Patio-On-152-Acre-Farm.h93545930.Hotel-Information) Berger 10/10 Exceptional (2 reviews) "Very clean,family friendly, even though it was 7 miles out of town they were very Accommodating,they came to puck us up at the train station and there's a van that will take you into town and you can take the trolley to all the wineries,shopping, we all loved our stay,i would definitely recommend to anyone who enjoys the fram life, they have lots of history, and animals, thank you Susan and Mike for all that you did to make our stay memorable, we would definitely come back. " [](https://www.expedia.com/Berger-Hotels-Peaceful-Guest-Home-W-Patio-On-152-Acre-Farm.h93545930.Hotel-Information) Apartment ![Apartment (0 Bedroom) | Interior](https://images.trvl-media.com/lodging/94000000/93540000/93537800/93537800/2bc9887f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (0 Bedroom) | Interior](https://images.trvl-media.com/lodging/94000000/93540000/93537800/93537800/21812dc2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (0 Bedroom) | Interior](https://images.trvl-media.com/lodging/94000000/93540000/93537800/93537800/9a29db2b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (0 Bedroom) | Interior](https://images.trvl-media.com/lodging/94000000/93540000/93537800/93537800/fffa75b7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Lovely Couples Escape on Mississippi River! [](https://www.expedia.com/St-Charles-Hotels-Lovely-Couples-Escape-On-Mississippi-River.h93537800.Hotel-Information) St. Charles 10/10 Exceptional (2 reviews) "Amazing place to stay, quiet and relaxing would definitely stay there again" [](https://www.expedia.com/St-Charles-Hotels-Lovely-Couples-Escape-On-Mississippi-River.h93537800.Hotel-Information) Cottage ![House (1 Bedroom) | Interior](https://images.trvl-media.com/lodging/94000000/93540000/93537500/93537498/8d018067.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (1 Bedroom) | Interior](https://images.trvl-media.com/lodging/94000000/93540000/93537500/93537498/954630bc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (1 Bedroom) | Interior](https://images.trvl-media.com/lodging/94000000/93540000/93537500/93537498/dba34dbc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (1 Bedroom) | Interior](https://images.trvl-media.com/lodging/94000000/93540000/93537500/93537498/82409c69.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Reubling House - Modern-rustic Cabin! [](https://www.expedia.com/Defiance-Hotels-The-Reubling-House-Modern-Rustic-Cabin.h93537498.Hotel-Information) Defiance 10/10 Exceptional (1 review) [](https://www.expedia.com/Defiance-Hotels-The-Reubling-House-Modern-Rustic-Cabin.h93537498.Hotel-Information) Apartment ![1 bedroom, individually decorated, individually furnished, free WiFi](https://images.trvl-media.com/lodging/100000000/99340000/99335800/99335703/bd9372e3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![40-inch TV with cable channels, fireplace](https://images.trvl-media.com/lodging/100000000/99340000/99335800/99335703/c08783b3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![40-inch TV with cable channels, fireplace](https://images.trvl-media.com/lodging/100000000/99340000/99335800/99335703/cac8e009.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/100000000/99340000/99335800/99335703/0d35e599.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hidden Gem | JZ Vacation Rentals [](https://www.expedia.com/St-Louis-Hotels-Charming-Studio-In-CWE-JZ-Vacation-Rentals.h99335703.Hotel-Information) Central West End 8.0/10 Very Good (1 review) [](https://www.expedia.com/St-Louis-Hotels-Charming-Studio-In-CWE-JZ-Vacation-Rentals.h99335703.Hotel-Information) Apartment ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/95000000/94540000/94537900/94537855/e81d3075.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/95000000/94540000/94537900/94537855/04e24b0f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2 Bedrooms) | Front of property](https://images.trvl-media.com/lodging/95000000/94540000/94537900/94537855/8e7f9af6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/95000000/94540000/94537900/94537855/001a7597.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### 'the Ruebling House' Historic Defiance Apartment! [](https://www.expedia.com/Defiance-Hotels-The-Ruebling-House-Historic-Defiance-Apartment.h94537855.Hotel-Information) Defiance 10/10 Exceptional (1 review) "This was are first family Vacation and are stay was amazing nice and clean with plenty of space. I would definitely recommend to a friend." [](https://www.expedia.com/Defiance-Hotels-The-Ruebling-House-Historic-Defiance-Apartment.h94537855.Hotel-Information) Cottage ![House (5 Bedrooms) | Interior](https://images.trvl-media.com/lodging/95000000/94500000/94496800/94496740/43fade66.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (5 Bedrooms) | Interior](https://images.trvl-media.com/lodging/95000000/94500000/94496800/94496740/442c326a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (5 Bedrooms) | Interior](https://images.trvl-media.com/lodging/95000000/94500000/94496800/94496740/d67a983a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (5 Bedrooms) | Interior](https://images.trvl-media.com/lodging/95000000/94500000/94496800/94496740/b3b83dfd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### 'hidden Paradise' on 5 Acres w/ Hot Tub & Deck! [](https://www.expedia.com/St-Louis-Hotels-Hidden-Paradise-On-5-Acres-Outdoor-Pool-Deck.h94496740.Hotel-Information) Florissant 10/10 Exceptional (1 review) "Beautiful well kept secret in a very peaceful setting: we had a large family Thanksgiving week in this beautiful place. There was more than enough rooms for four families to come together and still have enough room for dining visitors. It is beyond well equipped and you should contact the owner before you bring unnecessary items. Great hot tub. Spacious and well equipped baths and showers with all personal supplies and plush towels. Beds were all amazing. There is a great playroom... [](https://www.expedia.com/St-Louis-Hotels-Hidden-Paradise-On-5-Acres-Outdoor-Pool-Deck.h94496740.Hotel-Information) [See all vacation rentals](https://expedia.com/Hotel-Search?startDate=2026-03-26&endDate=2026-03-29®ionId=6058818&adults=2&sort=RECOMMENDED&stay_options_group=vacation_rentals_option&categorySearch=vacation_rentals_option&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.com/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FNortheast-Missouri-Hotels.d6058818.Travel-Guide-Hotels)[ Sign up, it's free ](https://expedia.com/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FNortheast-Missouri-Hotels.d6058818.Travel-Guide-Hotels) ## Stay near popular Central United States attractions ![Busch Stadium](https://images.trvl-media.com/place/3284/670cccfc-c300-4998-a42c-96757eeed295.jpg) Photo by Kelsey Fotovich ### Busch Stadium 4.6/5 (2,624 reviews) Catch an event at Busch Stadium during your trip to St. Louis. Experience the area's fascinating museums or attend a baseball game. [See properties](https://www.expedia.com/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=502872) ![Aerial view of vibrant downtown St. Louis with Enterprise Center and St. Louis Wheel, St. Louis, Missouri, United States.](https://images.trvl-media.com/place/502873/da730472-6151-40a1-b074-013a6c50d0f4.jpg) ### Enterprise Center 4.3/5 (835 reviews) Catch an event at Enterprise Center during your trip to St. Louis. Experience the area's fascinating museums or attend a baseball game. [See properties](https://www.expedia.com/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=502873) ![Caption---- Penguins at The St. Louis, MO Zoo](https://images.trvl-media.com/place/502878/d236ddaf-a463-4f53-858a-6c1f9c4e02c5.jpg) ### St. Louis Zoo 4.6/5 (2,379 reviews) In the middle of St. Louis, meet the exotic and endangered animals that live in meticulously recreated ecosystems from all over the world. [See properties](https://www.expedia.com/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=502878) ![Saint Louis is a City and Urban Center is Missouri with the Iconic Arch](https://images.trvl-media.com/place/6058090/0265bc5b-4681-44d3-90f6-25e6868a0534.jpg) ### Dome at America’s Center 4.1/5 (804 reviews) Catch an event at Dome at America’s Center during your trip to St. Louis. Experience the area's fascinating museums and great live music. [See properties](https://www.expedia.com/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6058090) ![Dark blue hour](https://images.trvl-media.com/place/3284/04b315ae-9f95-42cd-a17d-2221fbcbadcb.jpg) Photo by Rayna Kinley ### City Museum 4.5/5 (2,067 reviews) This quirky children’s museum invites visitors to crawl through whales, climb into tree houses and whiz down three-story slides. [See properties](https://www.expedia.com/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6069375) ![Grand Basin looking from top of Art Hill in Forest Park, St. Louis, Missouri](https://images.trvl-media.com/place/6005687/6a48afd8-f12d-4336-91f1-21e5f7dcf5c4.jpg) ### Forest Park 4.6/5 (2,094 reviews) Nature, history and cultural institutions come together in one of the United States’ largest urban parks, which buzzes with St. Louis’ dynamic community spirit. [See properties](https://www.expedia.com/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6005687) ### America's Center Convention Complex 4.4/5 (256 reviews) Learn about the events happening at America's Center Convention Complex during your trip to St. Louis. Experience the area's fascinating museums and great live music. [See properties](https://www.expedia.com/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6170694) ### Hollywood Casino Amphitheatre 4.1/5 (392 reviews) You can make plans for a show at Hollywood Casino Amphitheatre during your stay in Maryland Heights. Experience the acclaimed theater scene or attend a sporting event in this family-friendly area. [See properties](https://www.expedia.com/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6174066) ## Learn more about Northeast Missouri Great live music, sports teams, and popular sights from St. Louis Union Station to Busch Stadium—explore Northeast Missouri, a family-friendly destination also known for its theaters. [See all hotels in Northeast Missouri](https://www.expedia.com/Hotel-Search?startDate=2026-03-12&endDate=2026-03-13&adults=2®ionId=6058818) ![Grant\'s Farm which includes heritage architecture](https://images.trvl-media.com/place/6069377/88294c82-c384-49b1-b936-14bc595df677.jpg?impolicy=fcrop&w=900&h=506&p=1&q=high) ## Top Northeast Missouri Hotel Reviews ![Drury Inn & Suites St. Louis Union Station](https://images.trvl-media.com/lodging/1000000/40000/37700/37651/151222b4_y.jpg) ### Drury Inn & Suites St. Louis Union Station 10/10 Excellent "Unique environment, clean rooms, historic feel. " [](https://expedia.com/St-Louis-Hotels-Drury-Inn-St-Louis-At-Union-Station.h37651.Hotel-Information) ![Pear Tree Inn St. Louis Airport](https://images.trvl-media.com/lodging/2000000/1100000/1096600/1096579/fc156cf2_y.jpg) ### Pear Tree Inn St. Louis Airport 10/10 Excellent "Perfect location. Great service. Will book again " [](https://expedia.com/St-Louis-Hotels-Pear-Tree-Inn-St-Louis-Airport.h1096579.Hotel-Information) ![Angad Arts Hotel St. Louis, Tapestry Collection by Hilton](https://images.trvl-media.com/lodging/28000000/27620000/27617000/27616925/25bc97a8_y.jpg) ### Angad Arts Hotel St. Louis, Tapestry Collection by Hilton 10/10 Excellent "The room was soooooo cute!!! Loved all of the art! Very close to Fox Theater and University. The rooftop bar was perfection and the Blueberry Lemon Drop was delicious." [](https://expedia.com/St-Louis-Hotels-Angad-Arts-Hotel-St-Louis.h27616925.Hotel-Information) ![Home2 Suites by Hilton St. Louis Downtown](https://images.trvl-media.com/lodging/77000000/76520000/76510800/76510729/104b5741_y.jpg) ### Home2 Suites by Hilton St. Louis Downtown 10/10 Excellent "Everything!" [](https://expedia.com/St-Louis-Hotels-Home2-Suites-St-Louis-Downtown.h76510729.Hotel-Information) ![Magnolia Hotel St. Louis, a Tribute Portfolio Hotel](https://images.trvl-media.com/lodging/9000000/8140000/8132000/8131949/4b87c2a3_y.jpg) ### Magnolia Hotel St. Louis, a Tribute Portfolio Hotel 10/10 Excellent "Great service, and the room was perfect." [](https://expedia.com/St-Louis-Hotels-Magnolia-Hotel-St-Louis.h8131949.Hotel-Information) ![Ameristar Casino Resort and Spa](https://images.trvl-media.com/lodging/2000000/1880000/1873300/1873292/c42cf5fe_y.jpg) ### Ameristar Casino Resort and Spa 10/10 Excellent "Large, clean rooms. Curteous, helpful staff. Great dining options" [](https://expedia.com/St-Louis-Hotels-Ameristar-Casino-Resort-And-Spa.h1873292.Hotel-Information) ![Clayton Plaza Hotel & Extended Stay](https://images.trvl-media.com/lodging/1000000/20000/18200/18144/b3c5d3cd_y.jpg) ### Clayton Plaza Hotel & Extended Stay 10/10 Excellent "Great place to stay! Clean rooms, comfortable beds, and great breakfast! Highly recommend if you’re looking for a place to stay! " [](https://expedia.com/St-Louis-Hotels-Clayton-Plaza-Hotel-Extended-Stay.h18144.Hotel-Information) ![Embassy Suites by Hilton St. Louis Downtown](https://images.trvl-media.com/lodging/5000000/4540000/4531500/4531472/d41360b0_y.jpg) ### Embassy Suites by Hilton St. Louis Downtown 10/10 Excellent "Staff is amazing! Valet is a wonderful option. So convenient. Breakfast and wind down evening drinks and snacks were wonderdul. I didn't love the pillows on the bed or the bed. Lacked some comfort." [](https://expedia.com/St-Louis-Hotels-Embassy-Suites-By-Hilton-St-Louis-Downtown.h4531472.Hotel-Information) ![Pear Tree Inn St. Louis Near Union Station](https://images.trvl-media.com/lodging/1000000/30000/26600/26572/0bb9dbf3_y.jpg) ### Pear Tree Inn St. Louis Near Union Station 10/10 Excellent "Excellent " [](https://expedia.com/St-Louis-Hotels-Pear-Tree-Inn-St-Louis-Near-Union-Station.h26572.Hotel-Information) ## More cheap stays in Northeast Missouri ![Motel 6 Hazelwood, MO](https://images.trvl-media.com/lodging/1000000/10000/500/457/82f143a9_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Motel 6 Hazelwood, MO 5781 Campus Ct Hazelwood MO $58 nightly $71 total Mar 1 - Mar 2 Total with taxes and fees 8.4/10 Very Good! (1,793 reviews) [](https://expedia.com/St-Louis-Hotels-Motel-6-Hazelwood.h457.Hotel-Information) ![Relax Inn Saint Charles ](https://images.trvl-media.com/lodging/2000000/1010000/1000800/1000712/3d3bc786_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Relax Inn Saint Charles 3800 Harry S Truman Blvd St. Charles MO $61 nightly $71 total Feb 27 - Feb 28 Total with taxes and fees 6.8/10 (1,003 reviews) [](https://expedia.com/St-Louis-Hotels-Relax-Inn-Saint-Charles.h1000712.Hotel-Information) ![Red Roof Inn PLUS+ St Louis - Forest Park/ Hampton Ave ](https://images.trvl-media.com/lodging/1000000/30000/24500/24411/3904d866_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Red Roof Inn PLUS+ St Louis - Forest Park/ Hampton Ave 5823 Wilson Avenue St. Louis MO $81 nightly $94 total Mar 2 - Mar 3 Total with taxes and fees 5.8/10 (1,003 reviews) [](https://expedia.com/St-Louis-Hotels-Red-Roof-Inn-PLUS-St-Louis-Forest-Park-Hampton-Ave.h24411.Hotel-Information) ![Americas Best Value Inn & Suites St. Louis, St. Charles Inn](https://images.trvl-media.com/lodging/1000000/70000/68200/68132/c17520b0_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Americas Best Value Inn & Suites St. Louis, St. Charles Inn 1310 Bass Pro Drive St. Charles MO $90 nightly $104 total Mar 1 - Mar 2 Total with taxes and fees 5.8/10 (1,000 reviews) [](https://expedia.com/St-Louis-Hotels-Americas-Best-Value-Inn-Suites-St-Louis.h68132.Hotel-Information) ![Pear Tree Inn St. Louis Airport](https://images.trvl-media.com/lodging/2000000/1100000/1096600/1096579/fc156cf2_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Pear Tree Inn St. Louis Airport 10810 Pear Tree Ln St. Ann MO $90 nightly $106 total Mar 3 - Mar 4 Total with taxes and fees 9.4/10 Exceptional! (2,830 reviews) [](https://expedia.com/St-Louis-Hotels-Pear-Tree-Inn-St-Louis-Airport.h1096579.Hotel-Information) ![Wingate by Wyndham St. Louis Airport](https://images.trvl-media.com/lodging/1000000/20000/18200/18172/f94bc4e7_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Wingate by Wyndham St. Louis Airport 10820 Pear Tree Lane St. Ann MO $102 nightly $120 total Mar 5 - Mar 6 Total with taxes and fees 9.2/10 Wonderful! (1,529 reviews) [](https://expedia.com/St-Louis-Hotels-Wingate-By-Wyndham-St-Louis-Airport.h18172.Hotel-Information) ## Hotels in Northeast Missouri with star-rating ![5 Star Hotels](https://images.trvl-media.com/lodging/1000000/30000/25600/25559/c6e0103a_z.jpg) 5 Star Hotels 1 properties [](https://expedia.com/5Star-Northeast-Missouri-Hotels.s50-0-d6058818.Travel-Guide-Filter-Hotels) ![4 Star Hotels](https://images.trvl-media.com/lodging/1000000/30000/23700/23677/6ae928dd_z.jpg) 4 Star Hotels 65 properties [](https://expedia.com/4Star-Northeast-Missouri-Hotels.s40-0-d6058818.Travel-Guide-Filter-Hotels) ![3 Star Hotels](https://images.trvl-media.com/lodging/20000000/19690000/19681400/19681371/84fffc75_z.jpg) 3 Star Hotels 197 properties [](https://expedia.com/3Star-Northeast-Missouri-Hotels.s30-0-d6058818.Travel-Guide-Filter-Hotels) ![2 Star Hotels](https://images.trvl-media.com/lodging/92000000/91830000/91828000/91827910/6717a2ac_z.jpg) 2 Star Hotels 307 properties [](https://expedia.com/2Star-Northeast-Missouri-Hotels.s20-0-d6058818.Travel-Guide-Filter-Hotels) ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rentals - [Bethel Hotels ](https://www.expedia.com/Bethel-Hotels.d553248634983325196.Travel-Guide-Hotels) - [Shelbyville Hotels ](https://www.expedia.com/Shelbyville-Hotels.d6351838.Travel-Guide-Hotels) - [Motels in Shelbyville ](https://www.expedia.com/Shelbyville-Motels.d6351838-aaMotels.Travel-Guide-Accommodation) - [Shelbina Hotels ](https://www.expedia.com/Shelbina-Hotels.d6046578.Travel-Guide-Hotels) - [Hotels near Shelby Coutny Historical Society and Museum ](https://www.expedia.com/Shelby-Coutny-Historical-Society-And-Museum-Hotels.0-l6317032-0.Travel-Guide-Filter-Hotels) - [Clarence Hotels ](https://www.expedia.com/Clarence-Hotels.d553248634983378200.Travel-Guide-Hotels) - [Motels in Shelbina ](https://www.expedia.com/Shelbina-Motels.d6046578-aaMotels.Travel-Guide-Accommodation) - [Vacation Homes in Shelbina ](https://www.expedia.com/Shelbina-Private-Vacation-Homes.d6046578-aaPrivateVacationHomes.Travel-Guide-Accommodation) - [Cabin Rentals in Shelbina ](https://www.expedia.com/Shelbina-Cabins.d6046578-aaCabins.Travel-Guide-Accommodation) - 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