Find hotels in Northeast Missouri, MO from $74
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Go beyond your typical stay in Northeast Missouri
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Sep 1 - Sep 2Tomorrow
Sep 2 - Sep 3This weekend
Sep 4 - Sep 6Next weekend
Sep 11 - Sep 13Our top choices for Northeast Missouri hotels
1. FairBridge Inn Express, Monroe City
FairBridge Inn Express, Monroe CityMonroe City
Darrin J.
$86 nightly
$93 total
Sep 9 - Sep 10
Total with taxes and fees
2. Super 8 by Wyndham Macon
Super 8 by Wyndham MaconMacon
Austin
$85 nightly
$93 total
Sep 11 - Sep 12
Total with taxes and fees
3. Americas Best Value Inn & Suites Macon at Sunset Dr
Americas Best Value Inn & Suites Macon at Sunset DrMacon
Mary
$70 nightly
$75 total
Sep 8 - Sep 9
Total with taxes and fees
4. Travelier Motel
Travelier MotelMacon
Jessica
$68 nightly
$74 total
Sep 2 - Sep 3
Total with taxes and fees
5. Prairie View Inn
Prairie View InnShelbina
Randy
$93 nightly
$102 total
Sep 2 - Sep 3
Total with taxes and fees
6. Lost Branch Lodge. Complete exterior remodel, spring 2026!
Lost Branch Lodge. Complete exterior remodel, spring 2026!Brashear
Melissa W.
Vacation Rentals in Northeast Missouri
Cabin
Cannon Dam Cabins
Cannon Dam CabinsPerry
"Cozy and well equipped with everything we may have needed"
Apartment
White House at Grand Central
White House at Grand CentralGrand Center
"Staff was great and accommodating to my needs."
Apartment
Landing Furnished Apartments - Central West End
Landing Furnished Apartments - Central West EndCentral West End
"We booked a two bedroom for three people and the 2nd bedroom didn't have a bed! Contacted property, which was very responsive, but they couldn't do anything since we booked through Hotels. com"
Cottage
Peaceful Missouri Cabin Rental on 55 Acres!
Peaceful Missouri Cabin Rental on 55 Acres!Canton
"This is a great place to stay if you want to get away from the city. Rural enough to be quiet, but within easy driving distance to a city. Also perfect if you just want to stay on the property and really get away from city life, just bring your groceries. "
Vacation Home
Remodeled and Inviting Free EV
Remodeled and Inviting Free EVFenton
"It was nice to stay for a weekend but the neighborhood was nice I like the location where it wasn't too far from grocery stores food areas the only thing I was saying is it's nothing for the kids to do but overall I like it"
Vacation Home
Wine Country Getaway | JZ Vacation Rentals
Wine Country Getaway | JZ Vacation RentalsWashington
"Great communication, had a couple of leaks and shower flooded but the maintenance came right away to fix it. Overall clean, AC/Heat unit in each room, big kitchen, wonderful sitting area and decor."
Cottage
Updated Missouri Cabin Rental on Large Farm
Updated Missouri Cabin Rental on Large FarmCanton
"The cabin rental was a great stay. Had some connection problems with the t.v. couldn't get past the check out date. The wifi was easy to hook up. The cabin was clean and smelled fresh. Did have some problems with ants on the countertop. Great place to stay, enjoyed our visit."
Apartment
Lakefront Studio Guest Home on Hermann Wine Trail!
Lakefront Studio Guest Home on Hermann Wine Trail!New Haven
"Loved this property, very clean and well kept! Very pretty, lovely view. "
Apartment
Lovely Couples Escape on Mississippi River!
Lovely Couples Escape on Mississippi River!St. Charles
"Amazing place to stay, quiet and relaxing would definitely stay there again"
Apartment
The Merlot Bungalow Defiance Tiny Home on Trail
The Merlot Bungalow Defiance Tiny Home on TrailDefiance
"We enjoyed our stay very much! The place was very cute and conveniently located to explore Defiance! We will look to stay here again in the future!"
Cottage
Home w/ Trail Access on 19 Acres in Wright City!
Home w/ Trail Access on 19 Acres in Wright City!Wright City
"Great house in a beautiful setting. We enjoyed the quiet solitude and woodsy area. Very clean accommodations with every amenity available. "
Cottage
Walk to Tower Grove Park: St Louis Getaway
Walk to Tower Grove Park: St Louis GetawayTower Grove South
"great place and nice location"
Cottage
St Louis Home < 1 Mi to Forest Park!
St Louis Home < 1 Mi to Forest Park!Dogtown
"We really enjoyed our stay. A great house in a really fun residential area. Close to an area with a main town st with cool restaurants, bars and shops to walk around. "
Cottage
Peaceful Guest Home w/ Patio on 152-acre Farm
Peaceful Guest Home w/ Patio on 152-acre FarmBerger
"Very clean,family friendly, even though it was 7 miles out of town they were very Accommodating,they came to puck us up at the train station and there's a van that will take you into town and you can take the trolley to all the wineries,shopping, we all loved our stay,i would definitely recommend to anyone who enjoys the fram life, they have lots of history, and animals, thank you Susan and Mike for all that you did to make our stay memorable, we would definitely come back. "
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Stay near popular Northeast Missouri attractions
Photo by Carl Guttovz
Busch Stadium
9.4/10 (4,850 reviews)
Catch an event at Busch Stadium during your trip to St. Louis. Experience the area's acclaimed art scene or attend a baseball game.
Photo by Jeff White
St. Louis Zoo
9.2/10 (4,367 reviews)
In the middle of St. Louis, meet the exotic and endangered animals that live in meticulously recreated ecosystems from all over the world.
Enterprise Center
8.8/10 (1,597 reviews)
Catch an event at Enterprise Center during your trip to St. Louis. Experience the area's acclaimed art scene or attend a baseball game.
Dome at America’s Center
8.4/10 (1,229 reviews)
Catch an event at Dome at America’s Center during your trip to St. Louis. Experience the area's great live music and fascinating museums.
Forest Park
9.2/10 (3,389 reviews)
Nature, history and cultural institutions come together in one of the United States’ largest urban parks, which buzzes with St. Louis’ dynamic community spirit.
St. Louis University
8.6/10 (526 reviews)
Explore the campus of St. Louis University as part of your travels around St. Louis. Wander around the area's picturesque gardens or experience its fascinating museums.
City Museum
9.0/10 (3,209 reviews)
This quirky children’s museum invites visitors to crawl through whales, climb into tree houses and whiz down three-story slides.
America's Center Convention Complex
8.8/10 (306 reviews)
Learn about the events happening at America's Center Convention Complex during your trip to St. Louis. Experience the area's fascinating museums and acclaimed art scene.
Learn more about Northeast Missouri
Great live music, sports teams, and popular sights from St. Louis Zoo to St. Louis Union Station—explore Northeast Missouri, a family-friendly destination also known for its theaters.
See all hotels in Northeast Missouri
Top Northeast Missouri Hotel Reviews
Pear Tree Inn St. Louis Near Union Station
10/10 Excellent
"Everything is amazing! Walking distance to most attractions and secure parking. The restaurant had closed down, however there is a couple places within walking distance. Would stay here again!"
Angad Arts Hotel St. Louis, Tapestry Collection by Hilton
8/10 Good
"Overall, the hotel was very nice. The restaurant and staff super nice. The hotel had a night club upstairs so if that’s your thing this is the spot for you."
Renaissance St. Louis Airport Hotel
10/10 Excellent
"I recommend this Hotel 10 out of 10 every time I go back home this is where I stay. The staff and the facility. Everything is amazing."
Hollywood Casino & Hotel St. Louis
10/10 Excellent
"Great staff"
Tru By Hilton St. Louis Downtown
10/10 Excellent
"Enjoyed my stay there. Clean and very accommodating. Would book again"
The Royal Sonesta Chase Park Plaza St. Louis
10/10 Excellent
"All modern amenities with a touch of old world glam! Across from a beautiful walking/biking park and equipped with a beautiful pool, workout facility, comfortable beds, and several restaurants, all you need to have a wonderful travel experience!"
Pear Tree Inn St. Louis Airport
10/10 Excellent
"Clean and Friendly"
Live by Loews - St.Louis
10/10 Excellent
"First time staying at this brand. Loved this stay. In town for couple Cardinals games. Great walkable location, part of Ballpark Village, is right across street from ballpark. Super staff. Awesome indoor/outdoor bar/restaurant/lounge, plus a rooftop bar/lounge. Do have happy hr with reasonable drink prices. Hotel is newer, trendy vibe & decor. Hotel is quiet, heard no one in halls or room doors….don’t get the people who walk out their room and let door slam shut behind em. Doors are slow close which is nice. Bathrooms could use more hooks and maybe couple small shelves. Luggage carts are kept locked, need to ask for one. Def stay here again."
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
10/10 Excellent
"We stay every time we come down in a convenient area"
More cheap stays in Northeast Missouri
Motel 6 Hazelwood, MO
5781 Campus Ct Hazelwood MO
$60 nightly
$74 total
Oct 1 - Oct 2
Total with taxes and fees
8.4/10 Very Good! (2,189 reviews)
Days Inn and Suites by Wyndham St. Louis/Westport Plaza
1970 Craig Rd Maryland Heights MO
$68 nightly
$79 total
Sep 6 - Sep 7
Total with taxes and fees
4.4/10 (1,004 reviews)
Best Western St. Louis Inn
6224 Heimos Industrial Park Dr St. Louis MO
$75 nightly
$86 total
Sep 17 - Sep 18
Total with taxes and fees
8.4/10 Very Good! (1,105 reviews)
Pear Tree Inn St. Louis Arnold
1201 Drury Ln Arnold MO
$89 nightly
$102 total
Sep 8 - Sep 9
Total with taxes and fees
9.4/10 Exceptional! (1,003 reviews)
Pear Tree Inn St. Louis Airport
10810 Pear Tree Ln St. Ann MO
$90 nightly
$106 total
Sep 7 - Sep 8
Total with taxes and fees
9.2/10 Wonderful! (3,201 reviews)
Tru By Hilton St. Louis Downtown
1221 Locus Street St. Louis MO
$98 nightly
$114 total
Sep 9 - Sep 10
Total with taxes and fees
7.8/10 Good! (952 reviews)
Hotels in Northeast Missouri with star-rating
5 Star Hotels
1 properties
4 Star Hotels
54 properties
3 Star Hotels
186 properties
2 Star Hotels
207 properties
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- Visit Shelbina
