A large eye sculpture in a park surrounded by trees.

Find hotels in Northeast Missouri, MO from $73

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Our top choices for Northeast Missouri hotels

Pet friendly
Cabin
Enterprise Center
Breakfast included
Hot tub

1. FairBridge Inn Express, Monroe City

FairBridge Inn Express, Monroe City
Monroe City
United States
Patricia
$85 nightly
$92 total
Aug 17 - Aug 18
Total with taxes and fees
FairBridge Inn Express, Monroe City

2. Super 8 by Wyndham Macon

Super 8 by Wyndham Macon
Macon
United States
KARL
$88 nightly
$96 total
Aug 17 - Aug 18
Total with taxes and fees
Super 8 by Wyndham Macon

3. Americas Best Value Inn & Suites Macon at Sunset Dr

Americas Best Value Inn & Suites Macon at Sunset Dr
Macon
United States
William
$70 nightly
$75 total
Sep 9 - Sep 10
Total with taxes and fees
Americas Best Value Inn & Suites Macon at Sunset Dr

4. Travelier Motel

Travelier Motel
Macon
United States
Jessica
$73 nightly
$79 total
Aug 17 - Aug 18
Total with taxes and fees
Travelier Motel

5. Simple Rewards Inn Shelbina

Simple Rewards Inn Shelbina
Shelbina
United States
Randy
$85 nightly
$93 total
Aug 21 - Aug 22
Total with taxes and fees
Simple Rewards Inn Shelbina

6. Lost Branch Lodge. Complete exterior remodel, spring 2026!

Lost Branch Lodge. Complete exterior remodel, spring 2026!
Brashear
United States
Megan K.
Lost Branch Lodge. Complete exterior remodel, spring 2026!
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Vacation Rentals in Northeast Missouri

Cabin

Cannon Dam Cabins

Cannon Dam Cabins
Perry
"Cozy and well equipped with everything we may have needed"
Cannon Dam Cabins
Aparthotel

The Mercantile on the Katy Trail

The Mercantile on the Katy Trail
Hermann
"It’s an absolute must do! Such a cool little town right on the Katy Trail!"
The Mercantile on the Katy Trail
Aparthotel

Lighthouse Inn & Suites

Lighthouse Inn & Suites
Hannibal
"Wonderful place to stay!"
Lighthouse Inn & Suites
Apartment

White House at Grand Central

White House at Grand Central
Grand Center
"Staff was great and accommodating to my needs."
White House at Grand Central
Apartment

Lakefront Studio Guest Home on Hermann Wine Trail!

Lakefront Studio Guest Home on Hermann Wine Trail!
New Haven
"Loved this property, very clean and well kept! Very pretty, lovely view. "
Lakefront Studio Guest Home on Hermann Wine Trail!
Vacation Home

Remodeled and Inviting Free EV

Remodeled and Inviting Free EV
Fenton
"It was nice to stay for a weekend but the neighborhood was nice I like the location where it wasn't too far from grocery stores food areas the only thing I was saying is it's nothing for the kids to do but overall I like it"
Remodeled and Inviting Free EV
Apartment

Botanical Bliss | JZ Vacation Rentals

Botanical Bliss | JZ Vacation Rentals
Southwest Garden
Botanical Bliss | JZ Vacation Rentals
Apartment

Spacious 3-Bedroom with King Bed

Spacious 3-Bedroom with King Bed
Central West End
"Clean room nice area "
Spacious 3-Bedroom with King Bed
Cottage

Spacious Owensville Getaway w/ Winery On-site!

Spacious Owensville Getaway w/ Winery On-site!
Rosebud
"I don't even know where to start with this rental. We live in the country, this farmhouse was right up our alley!! I have stayed in a lot of rental properties, this one was like being at home. I could have stayed forever. The pond served as a wonderful experience for my daughter, she loves to fish and caught many fish. My husband enjoyed watching the sunrise every morning with his cup of coffee. The restaurant was in a league of it's own, the food was spectacular. The owner was VERY responsive,...
Spacious Owensville Getaway w/ Winery On-site!
Vacation Home

Wine Country Getaway | JZ Vacation Rentals

Wine Country Getaway | JZ Vacation Rentals
Washington
"Great communication, had a couple of leaks and shower flooded but the maintenance came right away to fix it. Overall clean, AC/Heat unit in each room, big kitchen, wonderful sitting area and decor."
Wine Country Getaway | JZ Vacation Rentals
Apartment

Near Wineries: Country Condo in New Haven

Near Wineries: Country Condo in New Haven
New Haven
"Clean and loved original architecture."
Near Wineries: Country Condo in New Haven
Apartment

Hidden Gem | JZ Vacation Rentals

Hidden Gem | JZ Vacation Rentals
Central West End
Hidden Gem | JZ Vacation Rentals
Apartment

Lovely Couples Escape on Mississippi River!

Lovely Couples Escape on Mississippi River!
St. Charles
"Amazing place to stay, quiet and relaxing would definitely stay there again"
Lovely Couples Escape on Mississippi River!
Cottage

Walk to Tower Grove Park: St Louis Getaway

Walk to Tower Grove Park: St Louis Getaway
Tower Grove South
"great place and nice location"
Walk to Tower Grove Park: St Louis Getaway
Cottage

Hillside Cabin on 43 Acres w/ Private Lake & View!

Hillside Cabin on 43 Acres w/ Private Lake & View!
Defiance
"We had a wonderful stay. The property is beautiful and well maintained, and the cabin is cute, comfortable, and well equipped. Nick is a very courteous host. We couldn’t have hoped for a better Thanksgiving getaway!"
Hillside Cabin on 43 Acres w/ Private Lake & View!
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Stay near popular Northeast Missouri attractions

A baseball stadium with a large crowd, a prominent arch structure, and various advertisements.
Photo by Carl Guttovz

Busch Stadium

9.4/10 (4,850 reviews)
Catch an event at Busch Stadium during your trip to St. Louis. Experience the area's acclaimed art scene or attend a baseball game.
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A bronze elephant sculpture with a pumpkin on its back, surrounded by greenery.
Photo by Jeff White

St. Louis Zoo

9.2/10 (4,367 reviews)
In the middle of St. Louis, meet the exotic and endangered animals that live in meticulously recreated ecosystems from all over the world.
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A cityscape with a prominent statue in the center, surrounded by various buildings and a large stadium.

Enterprise Center

8.8/10 (1,597 reviews)
Catch an event at Enterprise Center during your trip to St. Louis. Experience the area's acclaimed art scene or attend a baseball game.
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A modern building with large glass windows, surrounded by a garden with red and pink tulips and purple flowers.

Forest Park

9.2/10 (3,389 reviews)
Nature, history and cultural institutions come together in one of the United States’ largest urban parks, which buzzes with St. Louis’ dynamic community spirit.
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A cityscape with a prominent arch structure, various high-rise buildings, and a large government building.

Dome at America’s Center

8.4/10 (1,229 reviews)
Catch an event at Dome at America’s Center during your trip to St. Louis. Experience the area's great live music and fascinating museums.
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A tightrope walker balancing on a wire between buildings.

City Museum

9.0/10 (3,209 reviews)
This quirky children’s museum invites visitors to crawl through whales, climb into tree houses and whiz down three-story slides.
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A historic building with a large lawn, a flagpole with flags, and a clear blue sky.

St. Louis University

8.6/10 (526 reviews)
Explore the campus of St. Louis University as part of your travels around St. Louis. Wander around the area's picturesque gardens or experience its fascinating museums.
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America's Center Convention Complex

8.8/10 (306 reviews)
Learn about the events happening at America's Center Convention Complex during your trip to St. Louis. Experience the area's fascinating museums and acclaimed art scene.
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Learn more about Northeast Missouri

Great live music, sports teams, and popular sights from St. Louis Zoo to St. Louis Union Station—explore Northeast Missouri, a family-friendly destination also known for its theaters.

See all hotels in Northeast Missouri
A historic log cabin with a flagpole, hay bales, and autumn pumpkins.

Top Northeast Missouri Hotel Reviews

Pear Tree Inn St. Louis Airport

Pear Tree Inn St. Louis Airport

8/10 Good
"Everything was great. The hotel is clean and close to the airport. Your fee for keeping a vehicle overnight is ridiculous. That is my only complaint."
John 1-night trip
Posted 3 hours ago
Pear Tree Inn St. Louis Airport
Renaissance St. Louis Airport Hotel

Renaissance St. Louis Airport Hotel

8/10 Good
"No free wifi. Cannot remember the last time a hotel wanted to charge me for it. Very close to airport with fast shuttle and bar and restaurant that stays open until 10."
Joseph 1-night trip
Posted 4 hours ago
Renaissance St. Louis Airport Hotel
Drury Plaza Hotel St. Louis Union Station

Drury Plaza Hotel St. Louis Union Station

10/10 Excellent
"Everything was amazing. You won't be disappointed."
Wendy 2-night trip
Posted 6 hours ago
Drury Plaza Hotel St. Louis Union Station
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

10/10 Excellent
"staff"
Janet 2-night trip
Posted 7 hours ago
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
Hilton St. Louis at the Ballpark

Hilton St. Louis at the Ballpark

8/10 Good
"Starbucks inside the hotel 👍... Places to eat was all a short distance walk. My Room didn't have any garbage bags in any of the cans and the room had so many Nat Flies. I probably won't stay there again..."
Tim 3-night trip
Posted 15 hours ago
Hilton St. Louis at the Ballpark
Hollywood Casino & Hotel St. Louis

Hollywood Casino & Hotel St. Louis

10/10 Excellent
"Smell of fish in the hall outside room. Otherwise great."
Michael 1-night trip
Posted 18 hours ago
Hollywood Casino & Hotel St. Louis
Pear Tree Inn St. Louis Near Union Station

Pear Tree Inn St. Louis Near Union Station

10/10 Excellent
"Great place. Right downtown. View of the arch."
Mandy 1-night trip
Posted 1 day ago
Pear Tree Inn St. Louis Near Union Station
Moonrise Hotel

Moonrise Hotel

10/10 Excellent
"Beautiful building, staff was so friendly and fun to be around, security actually paid attention in the evening and parking was easy. Would stay again"
Kena 1-night trip
Posted 2 days ago
Moonrise Hotel
Home2 Suites by Hilton St. Louis Downtown

Home2 Suites by Hilton St. Louis Downtown

10/10 Excellent
"It was a great location for us."
Paul 3-night trip
Posted 3 days ago
Home2 Suites by Hilton St. Louis Downtown

More cheap stays in Northeast Missouri

Motel 6 Hazelwood, MO

Motel 6 Hazelwood, MO

5781 Campus Ct Hazelwood MO
$59 nightly
$73 total
Aug 23 - Aug 24
Total with taxes and fees
Motel 6 Hazelwood, MO
Best Western St. Louis Inn

Best Western St. Louis Inn

6224 Heimos Industrial Park Dr St. Louis MO
$68 nightly
$78 total
Aug 30 - Aug 31
Total with taxes and fees
8.4/10 Very Good! (1,078 reviews)
Best Western St. Louis Inn
Days Inn and Suites by Wyndham St. Louis/Westport Plaza

Days Inn and Suites by Wyndham St. Louis/Westport Plaza

1970 Craig Rd Maryland Heights MO
$68 nightly
$79 total
Aug 24 - Aug 25
Total with taxes and fees
4.4/10 (1,002 reviews)
Days Inn and Suites by Wyndham St. Louis/Westport Plaza
Pear Tree Inn St. Louis Arnold

Pear Tree Inn St. Louis Arnold

1201 Drury Ln Arnold MO
$90 nightly
$104 total
Aug 23 - Aug 24
Total with taxes and fees
9.4/10 Exceptional! (1,001 reviews)
Pear Tree Inn St. Louis Arnold
Tru By Hilton St. Louis Downtown

Tru By Hilton St. Louis Downtown

1221 Locus Street St. Louis MO
$89 nightly
$105 total
Aug 23 - Aug 24
Total with taxes and fees
Tru By Hilton St. Louis Downtown
Pear Tree Inn St. Louis Airport

Pear Tree Inn St. Louis Airport

10810 Pear Tree Ln St. Ann MO
$90 nightly
$106 total
Aug 23 - Aug 24
Total with taxes and fees
9.2/10 Wonderful! (3,159 reviews)
Pear Tree Inn St. Louis Airport

Hotels in Northeast Missouri with star-rating

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