A large eye sculpture in a park surrounded by trees.

Find hotels in Northeast Missouri, MO from $72

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Aug 24 - Aug 25
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Aug 25 - Aug 26
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Aug 28 - Aug 30
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Our top choices for Northeast Missouri hotels

Hotel
Cabin
Breakfast included
Pet friendly
Reserve now, pay later

1. FairBridge Inn Express, Monroe City

FairBridge Inn Express, Monroe City
Monroe City
United States
Darrin J.
$84 nightly
$91 total
Aug 31 - Sep 1
Total with taxes and fees
FairBridge Inn Express, Monroe City

2. Super 8 by Wyndham Macon

Super 8 by Wyndham Macon
Macon
United States
Austin
$82 nightly
$89 total
Aug 30 - Aug 31
Total with taxes and fees
Super 8 by Wyndham Macon

3. Americas Best Value Inn & Suites Macon at Sunset Dr

Americas Best Value Inn & Suites Macon at Sunset Dr
Macon
United States
Mary
$70 nightly
$75 total
Sep 8 - Sep 9
Total with taxes and fees
Americas Best Value Inn & Suites Macon at Sunset Dr

4. Travelier Motel

Travelier Motel
Macon
United States
Jessica
$73 nightly
$79 total
Aug 25 - Aug 26
Total with taxes and fees
Travelier Motel

5. Prairie View Inn

Prairie View Inn
Shelbina
United States
Randy
$83 nightly
$91 total
Aug 28 - Aug 29
Total with taxes and fees
Prairie View Inn

6. Lost Branch Lodge. Complete exterior remodel, spring 2026!

Lost Branch Lodge. Complete exterior remodel, spring 2026!
Brashear
United States
Megan K.
Lost Branch Lodge. Complete exterior remodel, spring 2026!
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Vacation Rentals in Northeast Missouri

Cabin

Cannon Dam Cabins

Cannon Dam Cabins
Perry
"Cozy and well equipped with everything we may have needed"
Cannon Dam Cabins
Aparthotel

Lighthouse Inn & Suites

Lighthouse Inn & Suites
Hannibal
"Wonderful place to stay!"
Lighthouse Inn & Suites
Apartment

White House at Grand Central

White House at Grand Central
Grand Center
"Staff was great and accommodating to my needs."
White House at Grand Central
Apartment

Landing Furnished Apartments - Central West End

Landing Furnished Apartments - Central West End
Central West End
"We booked a two bedroom for three people and the 2nd bedroom didn't have a bed! Contacted property, which was very responsive, but they couldn't do anything since we booked through Hotels. com"
Landing Furnished Apartments - Central West End
Cottage

Peaceful Missouri Cabin Rental on 55 Acres!

Peaceful Missouri Cabin Rental on 55 Acres!
Canton
"This is a great place to stay if you want to get away from the city. Rural enough to be quiet, but within easy driving distance to a city. Also perfect if you just want to stay on the property and really get away from city life, just bring your groceries. "
Peaceful Missouri Cabin Rental on 55 Acres!
Vacation Home

Remodeled and Inviting Free EV

Remodeled and Inviting Free EV
Fenton
"It was nice to stay for a weekend but the neighborhood was nice I like the location where it wasn't too far from grocery stores food areas the only thing I was saying is it's nothing for the kids to do but overall I like it"
Remodeled and Inviting Free EV
Apartment

Spacious 3-Bedroom with King Bed

Spacious 3-Bedroom with King Bed
Central West End
"Clean room nice area "
Spacious 3-Bedroom with King Bed
Apartment

Hidden Gem | JZ Vacation Rentals

Hidden Gem | JZ Vacation Rentals
Central West End
Hidden Gem | JZ Vacation Rentals
Cottage

Updated Missouri Cabin Rental on Large Farm

Updated Missouri Cabin Rental on Large Farm
Canton
"The cabin rental was a great stay. Had some connection problems with the t.v. couldn't get past the check out date. The wifi was easy to hook up. The cabin was clean and smelled fresh. Did have some problems with ants on the countertop. Great place to stay, enjoyed our visit."
Updated Missouri Cabin Rental on Large Farm
Apartment

Lakefront Studio Guest Home on Hermann Wine Trail!

Lakefront Studio Guest Home on Hermann Wine Trail!
New Haven
"Loved this property, very clean and well kept! Very pretty, lovely view. "
Lakefront Studio Guest Home on Hermann Wine Trail!
Apartment

Charming Berger Apt on 42-acre Farm w/ Pool Access

Charming Berger Apt on 42-acre Farm w/ Pool Access
Berger
Charming Berger Apt on 42-acre Farm w/ Pool Access
Cottage

Home w/ Trail Access on 19 Acres in Wright City!

Home w/ Trail Access on 19 Acres in Wright City!
Wright City
"Great house in a beautiful setting. We enjoyed the quiet solitude and woodsy area. Very clean accommodations with every amenity available. "
Home w/ Trail Access on 19 Acres in Wright City!
Apartment

Lovely Couples Escape on Mississippi River!

Lovely Couples Escape on Mississippi River!
St. Charles
"Amazing place to stay, quiet and relaxing would definitely stay there again"
Lovely Couples Escape on Mississippi River!
Cottage

Walk to Tower Grove Park: St Louis Getaway

Walk to Tower Grove Park: St Louis Getaway
Tower Grove South
"great place and nice location"
Walk to Tower Grove Park: St Louis Getaway
Apartment

Near Wineries: Country Condo in Stony Hill

Near Wineries: Country Condo in Stony Hill
New Haven
"Clean and loved original architecture."
Near Wineries: Country Condo in Stony Hill
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Stay near popular Northeast Missouri attractions

A baseball stadium with a large crowd, a prominent arch structure, and various advertisements.
Photo by Carl Guttovz

Busch Stadium

9.4/10 (4,850 reviews)
Catch an event at Busch Stadium during your trip to St. Louis. Experience the area's acclaimed art scene or attend a baseball game.
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A bronze elephant sculpture with a pumpkin on its back, surrounded by greenery.
Photo by Jeff White

St. Louis Zoo

9.2/10 (4,367 reviews)
In the middle of St. Louis, meet the exotic and endangered animals that live in meticulously recreated ecosystems from all over the world.
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A cityscape with a prominent statue in the center, surrounded by various buildings and a large stadium.

Enterprise Center

8.8/10 (1,597 reviews)
Catch an event at Enterprise Center during your trip to St. Louis. Experience the area's acclaimed art scene or attend a baseball game.
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A cityscape with a prominent arch structure, various high-rise buildings, and a large government building.

Dome at America’s Center

8.4/10 (1,229 reviews)
Catch an event at Dome at America’s Center during your trip to St. Louis. Experience the area's great live music and fascinating museums.
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A modern building with large glass windows, surrounded by a garden with red and pink tulips and purple flowers.

Forest Park

9.2/10 (3,389 reviews)
Nature, history and cultural institutions come together in one of the United States’ largest urban parks, which buzzes with St. Louis’ dynamic community spirit.
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A tightrope walker balancing on a wire between buildings.

City Museum

9.0/10 (3,209 reviews)
This quirky children’s museum invites visitors to crawl through whales, climb into tree houses and whiz down three-story slides.
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A historic building with a large lawn, a flagpole with flags, and a clear blue sky.

St. Louis University

8.6/10 (526 reviews)
Explore the campus of St. Louis University as part of your travels around St. Louis. Wander around the area's picturesque gardens or experience its fascinating museums.
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America's Center Convention Complex

8.8/10 (306 reviews)
Learn about the events happening at America's Center Convention Complex during your trip to St. Louis. Experience the area's fascinating museums and acclaimed art scene.
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Learn more about Northeast Missouri

Great live music, sports teams, and popular sights from St. Louis Zoo to St. Louis Union Station—explore Northeast Missouri, a family-friendly destination also known for its theaters.

See all hotels in Northeast Missouri
A historic log cabin with a flagpole, hay bales, and autumn pumpkins.

Top Northeast Missouri Hotel Reviews

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

10/10 Excellent
"Wonderful all around"
Brittany 1-night trip
Posted 1 hour ago
Angad Arts Hotel St. Louis, Tapestry Collection by Hilton
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

10/10 Excellent
"The second room was much better and more clean that the 1st room. Breakfast was solid with biscuits & gravy, sausage & scrambled eggs. Some yogurt & fruit as well. Bagels, cream cheese. A super neat pancake maker that makes the cutest lil pancakes! Apple juice, cranberry & orange too. Coca cola products for soft drinks. Cereal & milk provided. Pool indoor & outdoor looked very clean & pristine, so did the hot tub. They were spraying down the pool deck when I was walking down to breakfast."
Brittany 1-night trip
Posted 1 hour ago
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
Moonrise Hotel

Moonrise Hotel

10/10 Excellent
"Fantastic stay for a show on Delmar."
Robert 2-night trip
Posted 3 hours ago
Moonrise Hotel
Forest Park Hotel by MDR

Forest Park Hotel by MDR

8/10 Good
"Good property"
Jeremy 1-night trip
Posted 7 hours ago
Forest Park Hotel by MDR
21C Museum Hotel St Louis

21C Museum Hotel St Louis

10/10 Excellent
"Location"
Brenda 1-night trip
Posted 7 hours ago
21C Museum Hotel St Louis
Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

10/10 Excellent
"Always clean, staff friendly, breakfast is good."
scott 1-night trip
Posted 8 hours ago
Clayton Plaza Hotel & Extended Stay
Renaissance St. Louis Airport Hotel

Renaissance St. Louis Airport Hotel

8/10 Good
"Upon arrival staff was nice. Room was clean and cozy cold. Will be booking again"
Keshia 2-night trip
Posted 10 hours ago
Renaissance St. Louis Airport Hotel
Pear Tree Inn St. Louis Near Union Station

Pear Tree Inn St. Louis Near Union Station

10/10 Excellent
"Great price at a convenient location to downtown!"
Cynthia 1-night trip
Posted 10 hours ago
Pear Tree Inn St. Louis Near Union Station
River City Casino & Hotel

River City Casino & Hotel

8/10 Good
"Room was clean and quiet. Everything was great until we tried to shower the next morning and we had no hot water which sucked. Overall it was a nice place loved the tv screen in the mirror of the bathroom."
maureen 1-night trip
Posted 10 hours ago
River City Casino & Hotel

More cheap stays in Northeast Missouri

Motel 6 Hazelwood, MO

Motel 6 Hazelwood, MO

5781 Campus Ct Hazelwood MO
$59 nightly
$72 total
Aug 30 - Aug 31
Total with taxes and fees
Motel 6 Hazelwood, MO
Days Inn and Suites by Wyndham St. Louis/Westport Plaza

Days Inn and Suites by Wyndham St. Louis/Westport Plaza

1970 Craig Rd Maryland Heights MO
$67 nightly
$77 total
Aug 30 - Aug 31
Total with taxes and fees
Days Inn and Suites by Wyndham St. Louis/Westport Plaza
Best Western St. Louis Inn

Best Western St. Louis Inn

6224 Heimos Industrial Park Dr St. Louis MO
$68 nightly
$78 total
Aug 30 - Aug 31
Total with taxes and fees
Best Western St. Louis Inn
Pear Tree Inn St. Louis Arnold

Pear Tree Inn St. Louis Arnold

1201 Drury Ln Arnold MO
$88 nightly
$102 total
Aug 30 - Aug 31
Total with taxes and fees
9.4/10 Exceptional! (1,012 reviews)
Pear Tree Inn St. Louis Arnold
Pear Tree Inn St. Louis Airport

Pear Tree Inn St. Louis Airport

10810 Pear Tree Ln St. Ann MO
$88 nightly
$104 total
Aug 30 - Aug 31
Total with taxes and fees
9.2/10 Wonderful! (3,188 reviews)
Pear Tree Inn St. Louis Airport
Tru By Hilton St. Louis Downtown

Tru By Hilton St. Louis Downtown

1221 Locus Street St. Louis MO
$89 nightly
$105 total
Aug 31 - Sep 1
Total with taxes and fees
Tru By Hilton St. Louis Downtown

Hotels in Northeast Missouri with star-rating

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