Top 10 Hotels in Northeast Missouri (from $73) 2026 - Competitive Prices

A large eye sculpture in a park surrounded by trees.

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Go beyond your typical stay in Northeast Missouri

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Our top choices for Northeast Missouri hotels

A living room with a sofa, coffee table, and patterned rug. There are large windows with blinds, a chandelier, and a view of the outside.

A hotel hallway with a patterned carpet, doors, and a sign indicating room number 101.

A hotel room with two beds, a television, a lamp, and a painting on the wall.

A dining area with multiple tables and chairs, a kitchen area with a refrigerator and various kitchen items, and a window with curtains.

1. FairBridge Inn Express, Monroe City

Monroe City

Lona

$86 nightly

$93 total

Sep 9 - Sep 10

Total with taxes and fees

A hotel room with a bed, a sofa, a desk, a chair, and a small table.

A Super 8 hotel with a covered entrance and multiple windows.

A kitchenette with a coffee maker, toaster, microwave, and various kitchen utensils.

A bathroom with a sink, toilet, and bathtub. There is a towel rack with towels, a mirror, and a ceiling light.

2. Super 8 by Wyndham Macon

Macon

Austin

$82 nightly

$89 total

Sep 13 - Sep 14

Total with taxes and fees

A compact kitchen with wooden cabinets, a coffee machine, and a dining area with metal chairs.

A living room with a black leather sofa, two black chairs, a potted plant, and a small table.

A compact kitchenette with a microwave, a small refrigerator, a coffee maker, and a telephone on a wooden dresser.

A neatly made bed with a brown quilted bedspread, a decorative pillow with a heart-shaped towel, and a bedside table with a lamp.

3. Americas Best Value Inn & Suites Macon at Sunset Dr

Macon

Mary

$70 nightly

$75 total

Sep 9 - Sep 10

Total with taxes and fees

A stainless steel ice dispenser with a blue button labeled 'PUSH FOR ICE' in a kitchen setting.

A hotel room with two beds, green walls, and artwork.

A kitchen counter with fruits, a blender, and a refrigerator with a game display.

A motel with a sign advertising free continental breakfast and internet service.

4. Travelier Motel

Macon

Jessica

$68 nightly

$74 total

Sep 6 - Sep 7

Total with taxes and fees

A neatly made bed with a white quilt, a dark wooden headboard, a bedside lamp, a red chair, and a wall decoration.

A long, narrow hallway with carpeted floors, doors on both sides, and a red chair in the distance.

A hotel lobby with a Christmas tree, red sofas, a wooden reception desk, and a sign for Simple Rewards Inn.

A room with a large window, a red chair, and a wall-mounted air conditioner.

5. Prairie View Inn

Shelbina

Randy

$88 nightly

$96 total

Sep 13 - Sep 14

Total with taxes and fees

A wooden bridge with a rope railing in a forested area.

A wooden staircase with a railing, a door, and a ceiling with fluorescent lights.

A modern kitchen with wooden cabinets, stainless steel appliances, and a large island.

A spacious living room with a high ceiling, wooden beams, a fireplace, and a dining area with a table and chairs.

6. Lost Branch Lodge. Complete exterior remodel, spring 2026!

Brashear

Melissa W.

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Vacation Rentals in Northeast Missouri

Cabin

A park with a pond, picnic tables, and a gazebo.

A small, well-lit kitchen with a dining table, chairs, a refrigerator, a microwave, and a television mounted on the wall.

A row of rustic, single-story buildings with a grassy lawn and picnic tables.

Cannon Dam Cabins

Perry

"Cozy and well equipped with everything we may have needed"

Aparthotel

A hotel room with a large bed, two bedside lamps, a modern bathroom, and a vibrant abstract painting on the wall.

A modern living room with a grey sofa, a white armchair, a coffee table, and a patterned rug. There is a kitchen in the background with white cabinets and a black door.

A swimming pool with lounge chairs and a covered seating area.

A compact kitchen with white cabinets, a microwave, a coffee maker, and a sink.

Lighthouse Inn & Suites

Hannibal

"Wonderful place to stay!"

Apartment

A spacious foyer with a grand staircase, a piano, and a large rug.

A spacious dining area with a round glass table, black metal chairs, and a wooden staircase leading to an upper level.

A backyard with a stone fire pit, two Adirondack chairs, and a hammock.

A hallway with wooden doors, a wall-mounted tree decoration, a small table with a plant, and a painting.

White House at Grand Central

Grand Center

"Staff was great and accommodating to my needs."

Cottage

A covered porch with a white door, two folding chairs, and a concrete walkway.

A kitchen with white cabinets, a granite countertop, a stainless steel refrigerator, a microwave, a toaster, and a coffee maker.

A living room with a sofa, a table, a TV, and a dining area with chairs.

A modern living room with a grey sofa, a dining table with chairs, a small side table, and a floor lamp.

Peaceful Missouri Cabin Rental on 55 Acres!

Canton

"This is a great place to stay if you want to get away from the city. Rural enough to be quiet, but within easy driving distance to a city. Also perfect if you just want to stay on the property and really get away from city life, just bring your groceries. "

Vacation Home

A modern kitchen with dark cabinetry, a marble countertop, and a central island.

A room with bunk beds, a desk with a computer, and a TV.

A hallway with a wooden handrail, a rug, and a door leading to another room.

A modern kitchen with dark cabinetry, a central island, and a dining area with a wooden table and chairs.

Remodeled and Inviting Free EV

Fenton

"It was nice to stay for a weekend but the neighborhood was nice I like the location where it wasn't too far from grocery stores food areas the only thing I was saying is it's nothing for the kids to do but overall I like it"

Aparthotel

A compact living space with a sofa, a TV, a kitchen area with a fridge, microwave, and coffee maker, and a dining table.

A modern kitchen with a wooden island, bar stools, and a flat-screen TV.

A compact kitchen with a marble backsplash, a refrigerator, a washing machine, and a dining area with chairs.

A living room with a sofa, armchair, and coffee table. There is a staircase with a railing and a door in the background.

The Mercantile on the Katy Trail

Hermann

"It’s an absolute must do! Such a cool little town right on the Katy Trail!"

Apartment

A modern hotel lobby with a marble reception desk, a TV mounted on the wall, and a seating area with chairs and a sofa.

A modern living room with a pool table, a seating area, and a large window offering a view of the outdoors.

A swimming pool with lounge chairs, a bar area, and a building with multiple balconies.

A modern gym with treadmills, ellipticals, and weight machines. Large windows offer views of a swimming pool and greenery.

Landing Furnished Apartments - Central West End

Central West End

"We booked a two bedroom for three people and the 2nd bedroom didn't have a bed! Contacted property, which was very responsive, but they couldn't do anything since we booked through Hotels. com"

Cottage

A modern kitchen with white cabinets, a granite countertop, a built-in stove, a microwave, and a stainless steel refrigerator.

A compact living space with a dining area, a sofa, and a television.

A living room with a beige sofa, a coffee table, a TV mounted on the wall, and a chair.

Updated Missouri Cabin Rental on Large Farm

Canton

"The cabin rental was a great stay. Had some connection problems with the t.v. couldn't get past the check out date. The wifi was easy to hook up. The cabin was clean and smelled fresh. Did have some problems with ants on the countertop. Great place to stay, enjoyed our visit."

Cottage

A compact living space with a kitchenette, a brown leather sofa, a wooden coffee table, and a view through a large window.

A kitchen with wooden cabinets, a stainless steel refrigerator, a sink, and a window with curtains.

A forested area with a gravel path, a parked car, and a red object that appears to be a piece of equipment.

A bedroom with a checkered bedspread, a wardrobe, and a ceiling light.

Home w/ Trail Access on 19 Acres in Wright City!

Wright City

"Great house in a beautiful setting. We enjoyed the quiet solitude and woodsy area. Very clean accommodations with every amenity available. "

Cottage

A modern kitchen with stainless steel appliances, wooden cabinets, and a built-in dishwasher.

A modern kitchen with a dishwasher, sink, and a coffee maker.

A modern kitchen with dark wooden cabinets, a white countertop, a stainless steel refrigerator, and a built-in microwave. There is a dining table with two chairs and a potted plant on it.

A bedroom with a bed, a ceiling fan, a window with blinds, a nightstand, and a potted plant.

Walk to Tower Grove Park: St Louis Getaway

Tower Grove South

"great place and nice location"

Apartment

A living room with a sofa, armchair, and coffee table. There is a ceiling fan, a TV mounted on the wall, and a window with blinds.

A modern kitchen with dark cabinets, a black refrigerator, a white stove, and a wooden floor.

A bedroom with a bed, a TV, a ceiling fan, and a hallway leading to another room.

A white door with a small mailbox and a mailbox with a bear figure on the front step.

Walk to Carondelet Park: Quiet Couple's Getaway

Carondelet

"We had a nice stay, close to things we wanted to do"

Apartment

A red building with a sign for 'Catala House' and a 'Massage House' sign.

A kitchen with white cabinets, a wooden door, and a window.

A cozy loft-style living room with a brown leather sofa, a blue ottoman, and a patterned rug.

A bedroom with a bed, a flat-screen TV mounted on the wall, a brick pillar, and a window with curtains.

New Melle Apartment Near Missouri Wine Country

Wentzville

"Apartment was wonderful! Very spacious and lots of furniture. Had a flat screen in the living room and bedroom that included Netflix and Prime. Air conditioner worked very well. Was very quiet and in a good location. Property manager was very friendly. There was even a very nice tea selection included with our stay. All amenities including, fridge, sinks, countertop burner, shower, washer, dryer, and toilet worked with no issues. All the dishes and mugs were clean. Plenty of towels to use during...

Cottage

A single-story house with a red front door, a brick foundation, and a small front yard with two trees.

A bedroom with a bed, nightstand, bedside table, window, and ceiling fan.

A living room with a yellow leather sofa, a ceiling fan, a dining table with chairs, a red door, and large windows with a view of the street.

A residential backyard with a patio, white chairs, and a brick wall.

St Louis Home < 1 Mi to Forest Park!

Dogtown

"We really enjoyed our stay. A great house in a really fun residential area. Close to an area with a main town st with cool restaurants, bars and shops to walk around. "

Cottage

A modern kitchen with stainless steel appliances, a large island, and leather chairs.

A hallway with a staircase, a white sofa, a plant, and a chandelier.

A spacious living room with a beige sofa, a wooden coffee table, and a chandelier.

A living room with a beige sofa, a round ottoman, a fireplace, and a chandelier.

Home 2 Mi to Dtwn St Louis: Great for Families!

Lafayette Square

"Clean space with so much character!"

Apartment

A spacious living room with a wooden ceiling, a sofa, a dining table, and a kitchen area visible through an open doorway.

A bedroom with a wooden headboard, a bed with a beige bedspread, a nightstand, and a dresser.

A covered outdoor patio with wooden flooring, metal chairs, tables, and ceiling fans.

Near Wineries: Country Condo in Stony Hill

New Haven

"Clean and loved original architecture."

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Stay near popular Northeast Missouri attractions

A bronze elephant sculpture with a pumpkin on its back, surrounded by greenery.

St. Louis Zoo

9.2/10 (4,367 reviews)

In the middle of St. Louis, meet the exotic and endangered animals that live in meticulously recreated ecosystems from all over the world.

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A baseball stadium with a large crowd, a prominent arch structure, and various advertisements.

Busch Stadium

9.4/10 (4,850 reviews)

Catch an event at Busch Stadium during your trip to St. Louis. Experience the area's acclaimed art scene or attend a baseball game.

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A cityscape with a prominent statue in the center, surrounded by various buildings and a large stadium.

Enterprise Center

8.8/10 (1,597 reviews)

Catch an event at Enterprise Center during your trip to St. Louis. Experience the area's acclaimed art scene or attend a baseball game.

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A cityscape with a prominent arch structure, various high-rise buildings, and a large government building.

Dome at America’s Center

8.4/10 (1,229 reviews)

Catch an event at Dome at America’s Center during your trip to St. Louis. Experience the area's fascinating museums and acclaimed art scene.

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A modern building with large glass windows, surrounded by a garden with red and pink tulips and purple flowers.

Forest Park

9.2/10 (3,389 reviews)

Nature, history and cultural institutions come together in one of the United States’ largest urban parks, which buzzes with St. Louis’ dynamic community spirit.

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A historic building with a large lawn, a flagpole with flags, and a clear blue sky.

St. Louis University

8.6/10 (526 reviews)

Explore the campus of St. Louis University as part of your travels around St. Louis. Wander around the area's picturesque gardens or experience its acclaimed theater scene.

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A tightrope walker balancing on a wire between buildings.

City Museum

9.0/10 (3,209 reviews)

This quirky children’s museum invites visitors to crawl through whales, climb into tree houses and whiz down three-story slides.

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America's Center Convention Complex

8.8/10 (306 reviews)

Learn about the events happening at America's Center Convention Complex during your trip to St. Louis. Experience the area's fascinating museums and acclaimed art scene.

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Learn more about Northeast Missouri

Great live music, sports teams, and popular sights from St. Louis Zoo to St. Louis Union Station—explore Northeast Missouri, a family-friendly destination also known for its theaters.

See all hotels in Northeast Missouri

A historic log cabin with a flagpole, hay bales, and autumn pumpkins.

Top Northeast Missouri Hotel Reviews

21C Museum Hotel St Louis

10/10 Excellent

"Excellent hotel , friendly , loved all public area including the pool"

Clayton Plaza Hotel & Extended Stay

8/10 Good

"Conveniently located with easy parking. The rooms have been renovated; the common areas and restaurant have not or do not appear to be. It's a bit of a mouse maze to get around inside. The bang for the buck is there for sure."

Pear Tree Inn St. Louis Airport

10/10 Excellent

"Always have a great stay here. Landon at the front desk is fantastic, always happy to offer suggestions of things to do in the area, and a generally happy attitude. Everyone else is fantastic as well, never had a bad experience with any of the staff. The cleaning crew are courteous and do a great job. Will always be my go-to hotel when I'm in the area!"

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

10/10 Excellent

"."

Home2 Suites by Hilton St. Louis Downtown

10/10 Excellent

"Valet parking expensive. Good breakfast. I didn’t walk the area when it got dark."

Pear Tree Inn St. Louis Near Union Station

10/10 Excellent

"Very easy check in. Friendly staff. Rooms were clean and maintained throughout our stay. Amenities were great. Parking was awesome! And free"

Live by Loews - St.Louis

10/10 Excellent

"This is an amazingly clean and comfortable hotel. It is directly across from the baseball field and there is a parking garage connected to the building for $40. It is a 10min walk to the Gateway Arch and plenty of restaurants to choose from. Right downtown and if there is no game going on it is extremely quiet. Not the loud hussle and bussle of most downtown areas."

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

10/10 Excellent

"Great place"

More cheap stays in Northeast Missouri

Motel 6 Hazelwood, MO

5781 Campus Ct Hazelwood MO

$60 nightly

$73 total

Oct 4 - Oct 5

Total with taxes and fees

8.4/10 Very Good! (2,192 reviews)

Best Western St. Louis Inn

6224 Heimos Industrial Park Dr St. Louis MO

$71 nightly

$82 total

Sep 13 - Sep 14

Total with taxes and fees

Sleep Inn & Suites O'Fallon MO - Technology Drive

1147 Technology Drive O'Fallon MO

$82 nightly

$97 total

Sep 27 - Sep 28

Total with taxes and fees

Pear Tree Inn St. Louis Arnold

1201 Drury Ln Arnold MO

$89 nightly

$102 total

Oct 4 - Oct 5

Total with taxes and fees

Pear Tree Inn St. Louis Airport

10810 Pear Tree Ln St. Ann MO

$89 nightly

$104 total

Oct 4 - Oct 5

Total with taxes and fees

9.2/10 Wonderful! (3,218 reviews)

Tru By Hilton St. Louis Downtown

1221 Locus Street St. Louis MO

$98 nightly

$114 total

Sep 13 - Sep 14

Total with taxes and fees

Hotels in Northeast Missouri with star-rating

Explore a world of travel with Expedia

Shelbina Vacation Rentals

Things to do in Northeast Missouri

Find hotels in Northeast Missouri, MO from $73

Upfront pricing

Treat yourself

Be picky

Go beyond your typical stay in Northeast Missouri

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for Northeast Missouri hotels

1. FairBridge Inn Express, Monroe City

2. Super 8 by Wyndham Macon

3. Americas Best Value Inn & Suites Macon at Sunset Dr

4. Travelier Motel

5. Prairie View Inn

6. Lost Branch Lodge. Complete exterior remodel, spring 2026!

Vacation Rentals in Northeast Missouri

Cannon Dam Cabins

Lighthouse Inn & Suites

White House at Grand Central

Peaceful Missouri Cabin Rental on 55 Acres!

Remodeled and Inviting Free EV

The Mercantile on the Katy Trail

Landing Furnished Apartments - Central West End

Updated Missouri Cabin Rental on Large Farm

Home w/ Trail Access on 19 Acres in Wright City!

Walk to Tower Grove Park: St Louis Getaway

Walk to Carondelet Park: Quiet Couple's Getaway

New Melle Apartment Near Missouri Wine Country

St Louis Home < 1 Mi to Forest Park!

Home 2 Mi to Dtwn St Louis: Great for Families!

Near Wineries: Country Condo in Stony Hill

Stay near popular Northeast Missouri attractions

St. Louis Zoo

Busch Stadium

Enterprise Center

Dome at America’s Center

Forest Park

St. Louis University

City Museum

America's Center Convention Complex

Learn more about Northeast Missouri

Top Northeast Missouri Hotel Reviews

21C Museum Hotel St Louis

Clayton Plaza Hotel & Extended Stay

Pear Tree Inn St. Louis Airport

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

Home2 Suites by Hilton St. Louis Downtown

Pear Tree Inn St. Louis Near Union Station

Live by Loews - St.Louis

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

More cheap stays in Northeast Missouri

Motel 6 Hazelwood, MO

Best Western St. Louis Inn

Sleep Inn & Suites O'Fallon MO - Technology Drive

Pear Tree Inn St. Louis Arnold

Pear Tree Inn St. Louis Airport

Tru By Hilton St. Louis Downtown

Hotels in Northeast Missouri with star-rating

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