Top 10 Hotels in Northeast Missouri (from $72) 2026 - Competitive Prices

A large eye sculpture in a park surrounded by trees.

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Go beyond your typical stay in Northeast Missouri

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Our top choices for Northeast Missouri hotels

A living room with a sofa, coffee table, and patterned rug. There are large windows with blinds, a chandelier, and a view of the outside.

A hotel hallway with a patterned carpet, doors, and a sign indicating room number 101.

A building with a covered entrance, American flag, and a sign indicating it's open.

A dining area with multiple tables and chairs, a kitchen area with a refrigerator and various kitchen items, and a window with curtains.

1. FairBridge Inn Express, Monroe City

Monroe City

Darrin J.

$84 nightly

$91 total

Sep 13 - Sep 14

Total with taxes and fees

A hotel room with a bed, a sofa, a desk, a chair, and a small table.

A hotel room with a bed, a desk with a computer, a chair, a TV, and a window with curtains.

A kitchenette with a coffee maker, toaster, microwave, and various kitchen utensils.

A bathroom with a sink, toilet, and bathtub. There is a towel rack with towels, a mirror, and a ceiling light.

2. Super 8 by Wyndham Macon

Macon

Austin

$86 nightly

$94 total

Sep 11 - Sep 12

Total with taxes and fees

A compact kitchen with wooden cabinets, a coffee machine, and a dining area with metal chairs.

A compact kitchenette with a microwave, a small refrigerator, a coffee maker, and a telephone on a wooden dresser.

A living room with a black leather sofa, two black chairs, a potted plant, and a small table.

A hotel lobby with a black leather sofa, two bar stools, a reception desk, and a sign indicating no refund policy.

3. Americas Best Value Inn & Suites Macon at Sunset Dr

Macon

Mary

$70 nightly

$75 total

Sep 8 - Sep 9

Total with taxes and fees

A hotel room with two beds, green walls, and artwork.

A room with a bed, a desk with a computer, a television, and a chair.

A hallway with a wooden door, a black refrigerator, and a microwave on top.

A row of motel buildings with a parking lot in front.

4. Travelier Motel

Macon

Jessica

$68 nightly

$74 total

Sep 1 - Sep 2

Total with taxes and fees

A neatly made bed with a white quilt, a dark wooden headboard, a bedside lamp, a red chair, and a wall decoration.

A long, narrow hallway with carpeted floors, doors on both sides, and a red chair in the distance.

A hotel lobby with a Christmas tree, red sofas, a wooden reception desk, and a sign for Simple Rewards Inn.

A building with a brick facade, a wooden door, and a neon 'OPEN' sign.

5. Prairie View Inn

Shelbina

Randy

$104 nightly

$114 total

Sep 1 - Sep 2

Total with taxes and fees

A wooden bridge with a rope railing in a forested area.

A spacious living room with a high ceiling, wooden beams, a fireplace, and a dining area with a table and chairs.

A building with a covered porch, stone pillars, and a gravel driveway.

A modern kitchen with wooden cabinets, stainless steel appliances, and a large island.

6. Lost Branch Lodge. Complete exterior remodel, spring 2026!

Brashear

Melissa W.

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Vacation Rentals in Northeast Missouri

Cabin

A park with a pond, picnic tables, and a gazebo.

A grassy area with a picnic table and a dog.

A row of rustic, single-story buildings with a grassy lawn and picnic tables.

Cannon Dam Cabins

Perry

"Cozy and well equipped with everything we may have needed"

Apartment

A spacious foyer with a grand staircase, a piano, and a large rug.

A spacious living room with a beige sofa, a dining area with a table and chairs, large windows, and a chandelier.

A hallway with wooden doors, a wall-mounted tree decoration, a small table with a plant, and a painting.

A spacious dining area with a round glass table, black metal chairs, and a wooden staircase leading to an upper level.

White House at Grand Central

Grand Center

"Staff was great and accommodating to my needs."

Aparthotel

A hotel room with a large bed, two bedside lamps, a modern bathroom, and a vibrant abstract painting on the wall.

A spacious bathroom with a large bathtub, a walk-in shower, and a vanity with a mirror.

A swimming pool with lounge chairs and a covered seating area.

A compact kitchen with white cabinets, a microwave, a coffee maker, and a sink.

Lighthouse Inn & Suites

Hannibal

"Wonderful place to stay!"

Apartment

A modern hotel lobby with a marble reception desk, a TV mounted on the wall, and a seating area with chairs and a sofa.

A swimming pool with lounge chairs, a bar area, and a building with multiple balconies.

A modern living area with a grey sofa, a glass coffee table, and a black leather sofa. There are large windows and a visible interior space beyond.

A modern living room with a pool table, a seating area, and a large window offering a view of the outdoors.

Landing Furnished Apartments - Central West End

Central West End

"We booked a two bedroom for three people and the 2nd bedroom didn't have a bed! Contacted property, which was very responsive, but they couldn't do anything since we booked through Hotels. com"

Cottage

A modern living room with a grey sofa, a dining table with chairs, a small side table, and a floor lamp.

A living room with a sofa, a table, a TV, and a dining area with chairs.

A kitchen with white cabinets, a granite countertop, a stainless steel refrigerator, a microwave, a toaster, and a coffee maker.

A forest clearing with several discarded tires and a rope swing.

Peaceful Missouri Cabin Rental on 55 Acres!

Canton

"This is a great place to stay if you want to get away from the city. Rural enough to be quiet, but within easy driving distance to a city. Also perfect if you just want to stay on the property and really get away from city life, just bring your groceries. "

Vacation Home

A modern kitchen with dark cabinetry, a marble countertop, and a central island.

A room with bunk beds, a desk with a computer, and a TV.

A hallway with a wooden handrail, a rug, and a door leading to another room.

A modern kitchen with dark cabinets, a large island with a marble countertop, and stainless steel appliances.

Remodeled and Inviting Free EV

Fenton

"It was nice to stay for a weekend but the neighborhood was nice I like the location where it wasn't too far from grocery stores food areas the only thing I was saying is it's nothing for the kids to do but overall I like it"

Apartment

A spacious room with a wooden dining table, chairs, a chandelier, and a bed with white bedding.

A bedroom with a bed, a desk, a chair, a bench, and a ceiling fan.

A red deck with wicker furniture and a blue umbrella, overlooking a residential area with houses and a dome-shaped building.

A spacious living area with a blue sofa, wooden flooring, and a chandelier.

Spacious 3-Bedroom with King Bed

Central West End

"Clean room nice area "

Vacation Home

A dining table with a clear glass top, surrounded by two chairs, a potted plant, and a set of white tableware.

A kitchen with white cabinets, stainless steel appliances, a granite countertop, and wooden flooring.

A modern living room with a blue sofa, a fireplace, a ceiling fan, and a TV mounted above the fireplace.

A living room with two armchairs, a large wall clock, a wooden staircase, and a welcome sign.

Forest Park Oasis | JZ Vacation Rentals

Kings Oak

"Great property with plenty of space. Nice sized dining room table for dinner. Beautiful family room and fire place. Nicely decorated. "

Cottage

A covered porch with metal siding, a white door, and two folding chairs.

A modern kitchen with white cabinets, a black refrigerator, and a dining area with a wooden table and chairs.

A bedroom with a bed, a desk with a chair, a dresser, a ceiling fan, and a window with blinds.

A living room with a beige sofa, a coffee table, a TV mounted on the wall, and a chair.

Updated Missouri Cabin Rental on Large Farm

Canton

"The cabin rental was a great stay. Had some connection problems with the t.v. couldn't get past the check out date. The wifi was easy to hook up. The cabin was clean and smelled fresh. Did have some problems with ants on the countertop. Great place to stay, enjoyed our visit."

Vacation Home

A modern living room with a white sofa, a brown leather chair, a wooden staircase, and a flat-screen TV mounted on the wall.

A modern living room with a white sofa, a brown leather armchair, a small coffee table, and a chandelier.

A kitchen with green cabinets, a stainless steel sink, and wooden shelves holding glassware.

A bedroom with a large bed, a bench, a door, and a ceiling light.

Wine Country Getaway | JZ Vacation Rentals

Washington

"Great communication, had a couple of leaks and shower flooded but the maintenance came right away to fix it. Overall clean, AC/Heat unit in each room, big kitchen, wonderful sitting area and decor."

Apartment

A wooden deck with a rope fence, overlooking a lake and surrounded by trees.

A room with a large window, a microwave, a cabinet, and a sofa.

A kitchen with a large island, wooden cabinets, and a view of a lake.

A spacious living area with a sofa, a coffee table, and a dining table with a bench. There is a ceiling fan and a chandelier.

Lakefront Studio Guest Home on Hermann Wine Trail!

New Haven

"Loved this property, very clean and well kept! Very pretty, lovely view. "

Apartment

A wooden dock extending into a calm lake surrounded by lush greenery.

A white two-story house with a wooden deck and a staircase leading to the front door.

A swimming pool with lounge chairs and a house in the background.

A dining area with a wooden table, chairs, and a fruit basket.

Charming Berger Apt on 42-acre Farm w/ Pool Access

Berger

Apartment

A covered outdoor patio with wooden flooring, metal chairs, tables, and ceiling fans.

A two-story building with a covered porch and a staircase leading to the upper level.

A spacious living room with a wooden ceiling, a sofa, a dining table, and a kitchen area visible through an open doorway.

Near Wineries: Country Condo in Stony Hill

New Haven

"Clean and loved original architecture."

Cottage

A compact living space with a kitchenette, a brown leather sofa, a wooden coffee table, and a view through a large window.

A living room with a leather sofa, a television, a coffee table, and a fireplace.

A bedroom with a checkered bedspread, a wardrobe, and a ceiling light.

A forested area with a gravel path, a parked car, and a red object that appears to be a piece of equipment.

Home w/ Trail Access on 19 Acres in Wright City!

Wright City

"Great house in a beautiful setting. We enjoyed the quiet solitude and woodsy area. Very clean accommodations with every amenity available. "

Apartment

A spacious living area with a dining table, chairs, a sofa, and a fireplace. There is a kitchen area with a refrigerator, stove, and cabinets. The room has large windows and a ceiling fan.

A kitchen with a vintage stove, modern sink, and a black refrigerator.

A bedroom with a large bed, a chair, a desk, and a view of the outdoors.

A large, two-story house with a balcony, surrounded by a grassy field and trees.

Lovely Couples Escape on Mississippi River!

St. Charles

"Amazing place to stay, quiet and relaxing would definitely stay there again"

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Stay near popular Northeast Missouri attractions

A baseball stadium with a large crowd, a prominent arch structure, and various advertisements.

Busch Stadium

9.4/10 (4,850 reviews)

Catch an event at Busch Stadium during your trip to St. Louis. Experience the area's acclaimed art scene or attend a baseball game.

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A bronze elephant sculpture with a pumpkin on its back, surrounded by greenery.

St. Louis Zoo

9.2/10 (4,367 reviews)

In the middle of St. Louis, meet the exotic and endangered animals that live in meticulously recreated ecosystems from all over the world.

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A cityscape with a prominent statue in the center, surrounded by various buildings and a large stadium.

Enterprise Center

8.8/10 (1,597 reviews)

Catch an event at Enterprise Center during your trip to St. Louis. Experience the area's acclaimed art scene or attend a baseball game.

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A cityscape with a prominent arch structure, various high-rise buildings, and a large government building.

Dome at America’s Center

8.4/10 (1,229 reviews)

Catch an event at Dome at America’s Center during your trip to St. Louis. Experience the area's great live music and fascinating museums.

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A modern building with large glass windows, surrounded by a garden with red and pink tulips and purple flowers.

Forest Park

9.2/10 (3,389 reviews)

Nature, history and cultural institutions come together in one of the United States’ largest urban parks, which buzzes with St. Louis’ dynamic community spirit.

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A historic building with a large lawn, a flagpole with flags, and a clear blue sky.

St. Louis University

8.6/10 (526 reviews)

Explore the campus of St. Louis University as part of your travels around St. Louis. Wander around the area's picturesque gardens or experience its fascinating museums.

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A tightrope walker balancing on a wire between buildings.

City Museum

9.0/10 (3,209 reviews)

This quirky children’s museum invites visitors to crawl through whales, climb into tree houses and whiz down three-story slides.

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America's Center Convention Complex

8.8/10 (306 reviews)

Learn about the events happening at America's Center Convention Complex during your trip to St. Louis. Experience the area's fascinating museums and acclaimed art scene.

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Learn more about Northeast Missouri

Great live music, sports teams, and popular sights from St. Louis Zoo to St. Louis Union Station—explore Northeast Missouri, a family-friendly destination also known for its theaters.

See all hotels in Northeast Missouri

A historic log cabin with a flagpole, hay bales, and autumn pumpkins.

Top Northeast Missouri Hotel Reviews

Hollywood Casino & Hotel St. Louis

10/10 Excellent

"The room was great. Only downside was the tv in the living room didn't work properly but that's not enough for me to take a star away. The room was clean, staff was very helpful and friendly. You have to use a key card to even work the elevator so you don't have to worry about some random person walking about. I'd highly recommend. Plenty of parking too"

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

10/10 Excellent

"I was quite grateful for the embracing hospitality given by the staff. I found it to be exceptional service overall"

Clayton Plaza Hotel & Extended Stay

8/10 Good

"Multiple stays in the past"

Hilton St. Louis at the Ballpark

8/10 Good

"Location is perfect- able to walk to most of the attractions We did not get the room that we reserved but a food credit was given to us. Restaurants served good food. Breakfast was cold and too expensive. Overall great place- would stay there again."

St. Louis Union Station Hotel, Curio Collection by Hilton

8/10 Good

"The hotel was awesome, but it was very large and spread out. We had to walk a long way to get to our rooms. The staff was super helpful and friendly; however, the rooms were lacking. To start, the room fridge was not working and had to be swapped out. Then, when we decided to go to bed for the night, the sheets were dirty and didn't have a fitted sheet on the bed. Not to mention the little things, like ripped couch cushions and bad marks on the walls of the room. For such a nice place, we were disappointed with the rooms."

Renaissance St. Louis Airport Hotel

8/10 Good

"This place was very convenient considering my flight got in after midnight and it's so close to the airport. I only stayed over night and checked into another hotel in the city for the weekend. The rooms are old and need some updating (popcorn ceilings), but it was fine for a few hours of sleep and a hot shower."

Home2 Suites by Hilton St. Louis Downtown

8/10 Good

"Arrived at night and the people hanging around the area right near the hotel were questionable but glad there was a police officer full time at the entrance of the hotel. That was a bit unnerving otherwise our stay was fine. Hotel room was good and breakfast was ok but was so busy most containers were empty."

Forest Park Hotel by MDR

10/10 Excellent

"No complaints"

Courtyard by Marriott St. Louis Downtown/Convention Center

8/10 Good

"Rooms were clean and nice! The front desk staff and technicians were very kind, helpful, and fast when one of the rooms AC wasn’t working properly."

More cheap stays in Northeast Missouri

Motel 6 Hazelwood, MO

5781 Campus Ct Hazelwood MO

$60 nightly

$74 total

Sep 3 - Sep 4

Total with taxes and fees

8.4/10 Very Good! (2,189 reviews)

Days Inn and Suites by Wyndham St. Louis/Westport Plaza

1970 Craig Rd Maryland Heights MO

$68 nightly

$79 total

Sep 3 - Sep 4

Total with taxes and fees

Best Western St. Louis Inn

6224 Heimos Industrial Park Dr St. Louis MO

$75 nightly

$86 total

Sep 17 - Sep 18

Total with taxes and fees

8.4/10 Very Good! (1,103 reviews)

Pear Tree Inn St. Louis Arnold

1201 Drury Ln Arnold MO

$90 nightly

$104 total

Sep 6 - Sep 7

Total with taxes and fees

9.4/10 Exceptional! (1,003 reviews)

Pear Tree Inn St. Louis Airport

10810 Pear Tree Ln St. Ann MO

$90 nightly

$106 total

Sep 7 - Sep 8

Total with taxes and fees

9.2/10 Wonderful! (3,213 reviews)

Tru By Hilton St. Louis Downtown

1221 Locus Street St. Louis MO

$98 nightly

$114 total

Sep 7 - Sep 8

Total with taxes and fees

7.8/10 Good! (951 reviews)

Hotels in Northeast Missouri with star-rating

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Shelbina Vacation Rentals

Things to do in Northeast Missouri

Find hotels in Northeast Missouri, MO from $72

Upfront pricing

Treat yourself

Be picky

Go beyond your typical stay in Northeast Missouri

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for Northeast Missouri hotels

1. FairBridge Inn Express, Monroe City

2. Super 8 by Wyndham Macon

3. Americas Best Value Inn & Suites Macon at Sunset Dr

4. Travelier Motel

5. Prairie View Inn

6. Lost Branch Lodge. Complete exterior remodel, spring 2026!

Vacation Rentals in Northeast Missouri

Cannon Dam Cabins

White House at Grand Central

Lighthouse Inn & Suites

Landing Furnished Apartments - Central West End

Peaceful Missouri Cabin Rental on 55 Acres!

Remodeled and Inviting Free EV

Spacious 3-Bedroom with King Bed

Forest Park Oasis | JZ Vacation Rentals

Updated Missouri Cabin Rental on Large Farm

Wine Country Getaway | JZ Vacation Rentals

Lakefront Studio Guest Home on Hermann Wine Trail!

Charming Berger Apt on 42-acre Farm w/ Pool Access

Near Wineries: Country Condo in Stony Hill

Home w/ Trail Access on 19 Acres in Wright City!

Lovely Couples Escape on Mississippi River!

Stay near popular Northeast Missouri attractions

Busch Stadium

St. Louis Zoo

Enterprise Center

Dome at America’s Center

Forest Park

St. Louis University

City Museum

America's Center Convention Complex

Learn more about Northeast Missouri

Top Northeast Missouri Hotel Reviews

Hollywood Casino & Hotel St. Louis

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

Clayton Plaza Hotel & Extended Stay

Hilton St. Louis at the Ballpark

St. Louis Union Station Hotel, Curio Collection by Hilton

Renaissance St. Louis Airport Hotel

Home2 Suites by Hilton St. Louis Downtown

Forest Park Hotel by MDR

Courtyard by Marriott St. Louis Downtown/Convention Center

More cheap stays in Northeast Missouri

Motel 6 Hazelwood, MO

Days Inn and Suites by Wyndham St. Louis/Westport Plaza

Best Western St. Louis Inn

Pear Tree Inn St. Louis Arnold

Pear Tree Inn St. Louis Airport

Tru By Hilton St. Louis Downtown

Hotels in Northeast Missouri with star-rating

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