Top 10 Hotels in Northeast Missouri (from $72) 2026 - Competitive Prices

A large eye sculpture in a park surrounded by trees.

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Go beyond your typical stay in Northeast Missouri

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Our top choices for Northeast Missouri hotels

A living room with a sofa, coffee table, and patterned rug. There are large windows with blinds, a chandelier, and a view of the outside.

A building with a covered entrance, American flag, and a sign indicating it's open.

A hotel room with two beds, a television, a lamp, and a painting on the wall.

A hotel hallway with a patterned carpet, doors, and a sign indicating room number 101.

1. FairBridge Inn Express, Monroe City

Monroe City

Darrin J.

$82 nightly

$89 total

Aug 31 - Sep 1

Total with taxes and fees

A hotel room with a bed, a sofa, a desk, a chair, and a small table.

A bathroom with a sink, toilet, and bathtub. There is a towel rack with towels, a mirror, and a ceiling light.

A Super 8 hotel with a covered entrance and multiple windows.

A kitchenette with a coffee maker, toaster, microwave, and various kitchen utensils.

2. Super 8 by Wyndham Macon

Macon

Austin

$82 nightly

$89 total

Aug 30 - Aug 31

Total with taxes and fees

A compact kitchen with wooden cabinets, a coffee machine, and a dining area with metal chairs.

A living room with a black leather sofa, two black chairs, a potted plant, and a small table.

A neatly made bed with a brown quilted bedspread, a decorative pillow with a heart-shaped towel, and a bedside table with a lamp.

A compact kitchenette with a microwave, a small refrigerator, a coffee maker, and a telephone on a wooden dresser.

3. Americas Best Value Inn & Suites Macon at Sunset Dr

Macon

Mary

$63 nightly

$67 total

Sep 12 - Sep 13

Total with taxes and fees

A hotel room with two beds, green walls, and artwork.

A room with a bed, a desk with a computer, a television, and a chair.

A hallway with a wooden door, a black refrigerator, and a microwave on top.

A laundry room with two washing machines, a dryer, and a wall-mounted heater.

4. Travelier Motel

Macon

Jessica

$73 nightly

$79 total

Aug 29 - Aug 30

Total with taxes and fees

A neatly made bed with a white quilt, a dark wooden headboard, a bedside lamp, a red chair, and a wall decoration.

A hotel lobby with a Christmas tree, red sofas, a wooden reception desk, and a sign for Simple Rewards Inn.

A long, narrow hallway with carpeted floors, doors on both sides, and a red chair in the distance.

A room with a large window, a red chair, and a wall-mounted air conditioner.

5. Prairie View Inn

Shelbina

Randy

$85 nightly

$93 total

Aug 29 - Aug 30

Total with taxes and fees

A wooden bridge with a rope railing in a forested area.

A spacious living room with a high ceiling, wooden beams, a fireplace, and a dining area with a table and chairs.

A building with a covered porch, stone pillars, and a gravel driveway.

A wooden staircase with a railing, a door, and a ceiling with fluorescent lights.

6. Lost Branch Lodge. Complete exterior remodel, spring 2026!

Brashear

Melissa W.

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Vacation Rentals in Northeast Missouri

Cabin

A park with a pond, picnic tables, and a gazebo.

A row of rustic, single-story buildings with a grassy lawn and picnic tables.

A small, well-lit kitchen with a dining table, chairs, a refrigerator, a microwave, and a television mounted on the wall.

Cannon Dam Cabins

Perry

"Cozy and well equipped with everything we may have needed"

Aparthotel

A hotel room with a large bed, two bedside lamps, a modern bathroom, and a vibrant abstract painting on the wall.

A swimming pool with lounge chairs and a covered seating area.

A compact kitchen with white cabinets, a microwave, a coffee maker, and a sink.

A modern living room with a grey sofa, a white armchair, a coffee table, and a patterned rug. There is a kitchen in the background with white cabinets and a black door.

Lighthouse Inn & Suites

Hannibal

"Wonderful place to stay!"

Apartment

A spacious foyer with a grand staircase, a piano, and a large rug.

A hallway with wooden doors, a wall-mounted tree decoration, a small table with a plant, and a painting.

A backyard with a stone fire pit, two Adirondack chairs, and a hammock.

A spacious dining area with a round glass table, black metal chairs, and a wooden staircase leading to an upper level.

White House at Grand Central

Grand Center

"Staff was great and accommodating to my needs."

Cottage

A modern living room with a grey sofa, a dining table with chairs, a small side table, and a floor lamp.

A living room with a sofa, a table, a TV, and a dining area with chairs.

A kitchen with white cabinets, a granite countertop, a stainless steel refrigerator, a microwave, a toaster, and a coffee maker.

A forest clearing with several discarded tires and a rope swing.

Peaceful Missouri Cabin Rental on 55 Acres!

Canton

"This is a great place to stay if you want to get away from the city. Rural enough to be quiet, but within easy driving distance to a city. Also perfect if you just want to stay on the property and really get away from city life, just bring your groceries. "

Apartment

A modern hotel lobby with a marble reception desk, a TV mounted on the wall, and a seating area with chairs and a sofa.

A swimming pool with lounge chairs, a bar area, and a building with multiple balconies.

A modern living room with a pool table, a seating area, and a large window offering a view of the outdoors.

A modern gym with treadmills, ellipticals, and weight machines. Large windows offer views of a swimming pool and greenery.

Landing Furnished Apartments - Central West End

Central West End

"We booked a two bedroom for three people and the 2nd bedroom didn't have a bed! Contacted property, which was very responsive, but they couldn't do anything since we booked through Hotels. com"

Apartment

A bedroom with a bed, a dresser, a TV, and a door leading to another room.

A living room with a sectional sofa, a round coffee table, a fireplace, and a television mounted on the wall.

A modern kitchen with wooden cabinets, a stainless steel refrigerator, and a white countertop.

Botanical Bliss | JZ Vacation Rentals

Southwest Garden

Apartment

A spacious room with a wooden dining table, chairs, a chandelier, and a bed with white bedding.

A red deck with wicker furniture and a blue umbrella, overlooking a residential area with houses and a dome-shaped building.

A spacious living area with a blue sofa, wooden flooring, and a chandelier.

A modern living room with a blue sofa, a coffee table, and a ceiling fan.

Spacious 3-Bedroom with King Bed

Central West End

"Clean room nice area "

Cottage

A covered porch with metal siding, a white door, and two folding chairs.

A living room with a beige sofa, a coffee table, a TV mounted on the wall, and a chair.

A modern kitchen with white cabinets, a black refrigerator, and a dining area with a wooden table and chairs.

A modern kitchen with white cabinets, a granite countertop, a built-in stove, a microwave, and a stainless steel refrigerator.

Updated Missouri Cabin Rental on Large Farm

Canton

"The cabin rental was a great stay. Had some connection problems with the t.v. couldn't get past the check out date. The wifi was easy to hook up. The cabin was clean and smelled fresh. Did have some problems with ants on the countertop. Great place to stay, enjoyed our visit."

Apartment

A wooden dock extending into a calm lake surrounded by lush greenery.

A white two-story house with a wooden deck and a staircase leading to the front door.

A room with a wooden floor, a patterned chair, a television mounted on the wall, and a kitchen area visible through an open door.

A dining area with a wooden table, chairs, and a fruit basket.

Charming Berger Apt on 42-acre Farm w/ Pool Access

Berger

Cottage

A modern kitchen with stainless steel appliances, wooden cabinets, and a built-in dishwasher.

A modern kitchen with dark wooden cabinets, a white countertop, a stainless steel refrigerator, and a built-in microwave. There is a dining table with two chairs and a potted plant on it.

A modern kitchen with a dishwasher, sink, and a coffee maker.

A house with a front porch, a door, and a small garden area.

Walk to Tower Grove Park: St Louis Getaway

Tower Grove South

"great place and nice location"

Apartment

A living room with a sofa, armchair, and coffee table. There is a ceiling fan, a TV mounted on the wall, and a window with blinds.

A bedroom with a bed, a TV, a ceiling fan, and a hallway leading to another room.

A wooden deck with railings, a concrete foundation, and a view of a residential area with houses and trees.

A modern kitchen with dark cabinets, a black refrigerator, a white stove, and a wooden floor.

Walk to Carondelet Park: Quiet Couple's Getaway

Carondelet

"We had a nice stay, close to things we wanted to do"

Apartment

A modern kitchen with a wooden ceiling, a dining area with stools, and a seating area with a bench.

An outdoor patio with wooden benches and a covered seating area, surrounded by a gravel path and a fence.

A compact kitchen with a wooden ceiling, a small seating area, and a dining table.

A bedroom with a wooden ceiling, two windows with blinds, a bed with a striped blanket, a bedside table, and a white fan.

The Merlot Bungalow Defiance Tiny Home on Trail

Defiance

"We enjoyed our stay very much! The place was very cute and conveniently located to explore Defiance! We will look to stay here again in the future!"

Apartment

A red building with a sign for 'Catala House' and a 'Massage House' sign.

A bedroom with a bed, a flat-screen TV mounted on the wall, a brick pillar, and a window with curtains.

A kitchen with white cabinets, a wooden door, and a window.

A cozy loft-style living room with a brown leather sofa, a blue ottoman, and a patterned rug.

New Melle Apartment Near Missouri Wine Country

Wentzville

"Apartment was wonderful! Very spacious and lots of furniture. Had a flat screen in the living room and bedroom that included Netflix and Prime. Air conditioner worked very well. Was very quiet and in a good location. Property manager was very friendly. There was even a very nice tea selection included with our stay. All amenities including, fridge, sinks, countertop burner, shower, washer, dryer, and toilet worked with no issues. All the dishes and mugs were clean. Plenty of towels to use during...

Cottage

A log cabin interior with a stone fireplace, leather furniture, and mounted animal heads on the walls.

A kitchen with wooden cabinets, a stone island, and a hanging deer head.

A kitchen with wooden cabinets, granite countertops, a stainless steel stove, and a hanging light fixture.

A log cabin with a deck, outdoor seating, and potted plants.

Spacious Ozarks Family Home - Private Pool & Grill

Bourbon

"It's perfect 100% recommended."

Cottage

A modern kitchen with stainless steel appliances, a large island, and leather chairs.

A spacious living room with a beige sofa, a wooden coffee table, and a chandelier.

A hallway with a staircase, a white sofa, a plant, and a chandelier.

A living room with a beige sofa, a round ottoman, a fireplace, and a chandelier.

Home 2 Mi to Dtwn St Louis: Great for Families!

Lafayette Square

"Clean space with so much character!"

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Stay near popular Northeast Missouri attractions

A baseball stadium with a large crowd, a prominent arch structure, and various advertisements.

Busch Stadium

9.4/10 (4,850 reviews)

Catch an event at Busch Stadium during your trip to St. Louis. Experience the area's acclaimed art scene or attend a baseball game.

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A bronze elephant sculpture with a pumpkin on its back, surrounded by greenery.

St. Louis Zoo

9.2/10 (4,367 reviews)

In the middle of St. Louis, meet the exotic and endangered animals that live in meticulously recreated ecosystems from all over the world.

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A cityscape with a prominent statue in the center, surrounded by various buildings and a large stadium.

Enterprise Center

8.8/10 (1,597 reviews)

Catch an event at Enterprise Center during your trip to St. Louis. Experience the area's acclaimed art scene or attend a baseball game.

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A cityscape with a prominent arch structure, various high-rise buildings, and a large government building.

Dome at America’s Center

8.4/10 (1,229 reviews)

Catch an event at Dome at America’s Center during your trip to St. Louis. Experience the area's great live music and fascinating museums.

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A modern building with large glass windows, surrounded by a garden with red and pink tulips and purple flowers.

Forest Park

9.2/10 (3,389 reviews)

Nature, history and cultural institutions come together in one of the United States’ largest urban parks, which buzzes with St. Louis’ dynamic community spirit.

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A historic building with a large lawn, a flagpole with flags, and a clear blue sky.

St. Louis University

8.6/10 (526 reviews)

Explore the campus of St. Louis University as part of your travels around St. Louis. Wander around the area's picturesque gardens or experience its fascinating museums.

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A tightrope walker balancing on a wire between buildings.

City Museum

9.0/10 (3,209 reviews)

This quirky children’s museum invites visitors to crawl through whales, climb into tree houses and whiz down three-story slides.

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America's Center Convention Complex

8.8/10 (306 reviews)

Learn about the events happening at America's Center Convention Complex during your trip to St. Louis. Experience the area's fascinating museums and acclaimed art scene.

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Learn more about Northeast Missouri

Great live music, sports teams, and popular sights from St. Louis Zoo to St. Louis Union Station—explore Northeast Missouri, a family-friendly destination also known for its theaters.

See all hotels in Northeast Missouri

A historic log cabin with a flagpole, hay bales, and autumn pumpkins.

Top Northeast Missouri Hotel Reviews

The Royal Sonesta Chase Park Plaza St. Louis

10/10 Excellent

"This is a great historic hotel. Although some the bars and ballrooms from the early heyday have been renovated or repurposed, you can still admire some opulent architectural elements from the 1920s. Sonesta has done a great job bringing the property into the present while maintaining the beauty of its past. On a Saturday night, I walked by the vibrant and packed Chase Club that seemed to have a big following for karaoke and watched the Odyssey in one of the lobby's six theaters. The Chase is still the place in St. Louis."

Live by Loews - St.Louis

10/10 Excellent

"I loved this hotel! I didn’t want to leave! The balcony was everything! Everything was great about this hotel! Bed was like sleeping on a cloud. Yes it’s pricey, but lucky I got an upgrade and it was my birthday! I will come back."

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

10/10 Excellent

"Really unusual decor and a very fun stay. Location was good and parking was easy in the lot. Staff were not always easy to find though."

21C Museum Hotel St Louis

8/10 Good

"Located close to attractions, very well equipped on site dining, pool & exercise area were nice. The artistry of the bldg and art display were a plus."

Drury Plaza Hotel St. Louis Union Station

10/10 Excellent

"Daily breakfast was great and evening appetizers and drinks were a great benefit. Hotel was quiet and location made it easy to get to attractions."

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

10/10 Excellent

"Clean room, great staff! Love it here, but DO NOT stay on the 17th floor. It is under the 24hr gym and the 2 HUGE suites, that seem to party all noght long, lol. Not fun to wake up all the time because of that! Last year we were on the 14th floor and it was amazing! Pool table, shuffleboard, great bar/restaurant! Beautiful place!"

Moonrise Hotel

10/10 Excellent

"Easy free parking"

Forest Park Hotel by MDR

8/10 Good

"Free parking, clean big room, with microwave and fridge and affordable."

More cheap stays in Northeast Missouri

Motel 6 Hazelwood, MO

5781 Campus Ct Hazelwood MO

$60 nightly

$73 total

Sep 8 - Sep 9

Total with taxes and fees

Days Inn and Suites by Wyndham St. Louis/Westport Plaza

1970 Craig Rd Maryland Heights MO

$67 nightly

$78 total

Sep 8 - Sep 9

Total with taxes and fees

4.6/10 (1,002 reviews)

Best Western St. Louis Inn

6224 Heimos Industrial Park Dr St. Louis MO

$75 nightly

$86 total

Sep 17 - Sep 18

Total with taxes and fees

Pear Tree Inn St. Louis Arnold

1201 Drury Ln Arnold MO

$89 nightly

$102 total

Sep 8 - Sep 9

Total with taxes and fees

Pear Tree Inn St. Louis Airport

10810 Pear Tree Ln St. Ann MO

$89 nightly

$104 total

Sep 8 - Sep 9

Total with taxes and fees

Tru By Hilton St. Louis Downtown

1221 Locus Street St. Louis MO

$98 nightly

$114 total

Sep 7 - Sep 8

Total with taxes and fees

Hotels in Northeast Missouri with star-rating

Explore a world of travel with Expedia

Shelbina Vacation Rentals

Things to do in Northeast Missouri

Find hotels in Northeast Missouri, MO from $72

Upfront pricing

Treat yourself

Be picky

Go beyond your typical stay in Northeast Missouri

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for Northeast Missouri hotels

1. FairBridge Inn Express, Monroe City

2. Super 8 by Wyndham Macon

3. Americas Best Value Inn & Suites Macon at Sunset Dr

4. Travelier Motel

5. Prairie View Inn

6. Lost Branch Lodge. Complete exterior remodel, spring 2026!

Vacation Rentals in Northeast Missouri

Cannon Dam Cabins

Lighthouse Inn & Suites

White House at Grand Central

Peaceful Missouri Cabin Rental on 55 Acres!

Landing Furnished Apartments - Central West End

Botanical Bliss | JZ Vacation Rentals

Spacious 3-Bedroom with King Bed

Updated Missouri Cabin Rental on Large Farm

Charming Berger Apt on 42-acre Farm w/ Pool Access

Walk to Tower Grove Park: St Louis Getaway

Walk to Carondelet Park: Quiet Couple's Getaway

The Merlot Bungalow Defiance Tiny Home on Trail

New Melle Apartment Near Missouri Wine Country

Spacious Ozarks Family Home - Private Pool & Grill

Home 2 Mi to Dtwn St Louis: Great for Families!

Stay near popular Northeast Missouri attractions

Busch Stadium

St. Louis Zoo

Enterprise Center

Dome at America’s Center

Forest Park

St. Louis University

City Museum

America's Center Convention Complex

Learn more about Northeast Missouri

Top Northeast Missouri Hotel Reviews

The Royal Sonesta Chase Park Plaza St. Louis

Live by Loews - St.Louis

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

21C Museum Hotel St Louis

Drury Plaza Hotel St. Louis Union Station

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

Moonrise Hotel

Forest Park Hotel by MDR

More cheap stays in Northeast Missouri

Motel 6 Hazelwood, MO

Days Inn and Suites by Wyndham St. Louis/Westport Plaza

Best Western St. Louis Inn

Pear Tree Inn St. Louis Arnold

Pear Tree Inn St. Louis Airport

Tru By Hilton St. Louis Downtown

Hotels in Northeast Missouri with star-rating

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