Title: Houston Natural Science Museum Tours - Book Now | Expedia.com [Houston Natural Science Museum Hotels](https://expedia.com/Houston-Natural-Science-Museum-Hotels.0-l501256-0.Travel-Guide-Filter-Hotels)[Car Rentals in Houston Natural Science Museum](https://expedia.com/Car-Rentals-In-Houston-Natural-Science-Museum.d501256.Car-Rental-Guide)[Southeast Houston Vacations](https://expedia.com/Southeast-Houston.d553248635976479121.Destination-Travel-Guides) # Houston Natural Science Museum Tours ![Houston Natural Science Museum](https://images.trvl-media.com/place/501256/4e455af8-0f6d-48a6-81ba-874182e2abef.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ## Visit Houston Natural Science Museum Activities --- --- ## Plan a trip to see Houston Natural Science Museum Price found within the past 48 hours. Click for updated prices. ![Hilton Houston North](https://images.trvl-media.com/lodging/1000000/10000/900/809/72a26fde_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Hilton Houston North Northside Save 100% on your flight $288 per person Apr 30 - May 4 found 1 day ago Roundtrip flight included Atlanta (ATL) to Houston (IAH) 8.2/10 Very Good! (1,011 reviews) A little hard to reach and the shuttle options were subpar for early AM flights, but comfy rest and friendly staff. Reviewed on Mar 23, 2026 ![DoubleTree by Hilton Hotel & Suites Houston by the Galleria](https://images.trvl-media.com/lodging/1000000/30000/20200/20116/109ddc6c_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### DoubleTree by Hilton Hotel & Suites Houston by the Galleria Greater Uptown Save 100% on your flight $468 per person Apr 30 - May 4 found 1 day ago Roundtrip flight included Atlanta (ATL) to Houston (IAH) 8.2/10 Very Good! (3,480 reviews) yess 10/10 this was my second time staying at this hotel and it was amazing Reviewed on Mar 24, 2026 ![Kompose Residences Houston Cy-Fair](https://images.trvl-media.com/lodging/3000000/2280000/2270700/2270671/7d09d756_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Kompose Residences Houston Cy-Fair Save 100% on your flight $313 per person Apr 30 - May 4 found 1 day ago Roundtrip flight included Atlanta (ATL) to Houston (IAH) 9.6/10 Exceptional! (238 reviews) Very nice experience Reviewed on Mar 26, 2026 ### Browse tours and tickets to explore Houston Natural Science Museum ### Tours & day trips [See all 104 activities](https://expedia.com/things-to-do/search?&rid=501256&location=Houston+Natural+Science+Museum&filter.categories=ToursDayTrips) ![Houston: Space Center Houston Admission Ticket](https://mediaim.expedia.com/localexpert/4533482/0f94c67f-e1ca-4bd4-8e9a-fe09bf196a10.jpg?impolicy=resizecrop&rw=500&rh=280) ### Houston: Space Center Houston Admission Ticket 9/10 725 GetYourGuide reviews Free cancellation available $30 includes taxes & fees per adult [](https://www.expedia.com/things-to-do/houston-space-center-houston-admission-ticket.a4533482.activity-details?&rid=501256&location=Houston+Natural+Science+Museum&swp=off) ![Houston: Houston Botanic Garden Entry Ticket](https://mediaim.expedia.com/localexpert/46150646/bfc34474-c86f-4151-a485-5cc63efe2aab.jpg?impolicy=resizecrop&rw=500&rh=280) ### Houston: Houston Botanic 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(Air-Conditioned)](https://mediaim.expedia.com/localexpert/1358845/6701a89c-a4de-4a0b-ba2a-aae33d8a7249.jpg?impolicy=resizecrop&rw=500&rh=280) ### Astroville Tunnel Tour of Downtown Houston (Air-Conditioned) 2h 10/10 232 Viator reviews Free cancellation available $25 includes taxes & fees per adult [](https://www.expedia.com/things-to-do/astroville-tunnel-tour-of-downtown-houston-air-conditioned.a1358845.activity-details?&rid=501256&location=Houston+Natural+Science+Museum&swp=off) ![Houston TX 45-Minute Night ATV Riding](https://mediaim.expedia.com/localexpert/51853285/63e66a61-3bd2-4913-88e9-569304983597.jpg?impolicy=resizecrop&rw=500&rh=280) ### Houston TX 45-Minute Night ATV Riding 45m 10/10 4 GetYourGuide reviews Free cancellation available $100 includes taxes & fees per adult [](https://www.expedia.com/things-to-do/houston-tx-45-minute-night-atv-riding.a51853285.activity-details?&rid=501256&location=Houston+Natural+Science+Museum&swp=off) ![Explore Houston’s Hip Hop Culture on a 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[](https://www.expedia.com/things-to-do/houston-museum-of-natural-sciences-planetarium-ticket.a44640654.activity-details?&rid=501256&location=Houston+Natural+Science+Museum&swp=off) ![Houston's Official City & Mural Tour!](https://mediaim.expedia.com/localexpert/1341322/652df40a-01d1-4eab-a9d9-6067420f68b2.jpg?impolicy=resizecrop&rw=500&rh=280) ### Houston's Official City & Mural Tour! 1h 20m 8.6/10 247 Viator reviews Free cancellation available $45 includes taxes & fees per adult [](https://www.expedia.com/things-to-do/houstons-official-city-mural-tour.a1341322.activity-details?&rid=501256&location=Houston+Natural+Science+Museum&swp=off) ![From Houston: Crocodile Encounter Entry Ticket](https://mediaim.expedia.com/localexpert/49700169/eb0c6dc7-e1c2-4e15-8c1b-21b5935508bd.jpg?impolicy=resizecrop&rw=500&rh=280) ### From Houston: Crocodile Encounter Entry Ticket 10/10 1 GetYourGuide review Free cancellation available $22 includes taxes & fees per adult 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Private Sightseeing Cart Tour of Houston 1h 15m 9.6/10 81 Viator reviews Free cancellation available $54 includes taxes & fees per adult [](https://www.expedia.com/things-to-do/private-sightseeing-cart-tour-of-houston.a1225331.activity-details?&rid=501256&location=Houston+Natural+Science+Museum&swp=off) ![Polaris Slingshot Kemah boardwalk 3hr tour self guided](https://mediaim.expedia.com/localexpert/51818350/2ad28afa-ea76-439e-8c40-85a2941da2f8.jpg?impolicy=resizecrop&rw=500&rh=280) ### Polaris Slingshot Kemah boardwalk 3hr tour self guided 4h Free cancellation available $190 includes taxes & fees per traveler\* \*Get lower prices by selecting more than 2 adults [](https://www.expedia.com/things-to-do/kemah-boardwalk-slingshot-3hr-tour-self-guided.a51818350.activity-details?&rid=501256&location=Houston+Natural+Science+Museum&swp=off) ![Private Tour of Galveston](https://mediaim.expedia.com/localexpert/1225324/dbc61d2f-9da3-469e-9f08-d4f4b9616998.jpg?impolicy=resizecrop&rw=500&rh=280) ### Private Tour of Galveston 1h 30m 9.2/10 10 Viator reviews Free cancellation available $122 includes taxes & fees per adult [](https://www.expedia.com/things-to-do/private-tour-of-galveston.a1225324.activity-details?&rid=501256&location=Houston+Natural+Science+Museum&swp=off) ![Private Guided Pokemon Go Tour in Houston with Transportation](https://mediaim.expedia.com/localexpert/3168494/328bbc5f-bae2-4dff-994b-f44d8bc7624d.jpg?impolicy=resizecrop&rw=500&rh=280) ### Private Guided Pokemon Go Tour in Houston with Transportation 1h 30m 10/10 3 Viator reviews Free cancellation available $49 includes taxes & fees per adult [](https://www.expedia.com/things-to-do/private-guided-pokemon-go-tour-in-houston-with-transportation.a3168494.activity-details?&rid=501256&location=Houston+Natural+Science+Museum&swp=off) ![Explore Houston After Dark: Nightlife Tour of Downtown 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10/10 1 Viator review Free cancellation available $45 includes taxes & fees per adult [](https://www.expedia.com/things-to-do/houston-art-of-aromatherapy-perfume-class.a50805156.activity-details?&rid=501256&location=Houston+Natural+Science+Museum&swp=off) ![Cake Decorating in Houston](https://mediaim.expedia.com/localexpert/47194536/f077d313-397f-40f5-9615-af6d54b6f82b.jpg?impolicy=resizecrop&rw=500&rh=280) ### Cake Decorating in Houston 2h 10/10 1 Viator review Free cancellation available $70 includes taxes & fees per adult [](https://www.expedia.com/things-to-do/2-hours-cake-decorating-art-in-houston.a47194536.activity-details?&rid=501256&location=Houston+Natural+Science+Museum&swp=off) ![Private Shooting Airsoft Paint Gun and Spinning Art in Houston](https://mediaim.expedia.com/localexpert/47467707/48f40b3f-3a05-4e77-98f9-b45089f47b84.jpg?impolicy=resizecrop&rw=500&rh=280) ### Private Shooting Airsoft Paint Gun and Spinning Art in Houston 45m $98 includes taxes & fees per adult 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[](https://www.expedia.com/things-to-do/fluid-bear-public-art-class.a48922601.activity-details?&rid=501256&location=Houston+Natural+Science+Museum&swp=off) ### Attractions [See all 9 activities](https://expedia.com/things-to-do/search?&rid=501256&location=Houston+Natural+Science+Museum&filter.categories=Attractions) ![Houston CityPASS®: Admission to Top 5 Attractions](https://mediaim.expedia.com/localexpert/178506/3ca8e3a0-998f-4b2c-ba01-6e196943c20a.jpg?impolicy=resizecrop&rw=500&rh=280) ### Houston CityPASS®: Admission to Top 5 Attractions 9d 9/10 301 verified reviews Free cancellation available $82 includes taxes & fees per adult [](https://www.expedia.com/things-to-do/houston-citypass-admission-to-top-5-attractions.a178506.activity-details?&rid=501256&location=Houston+Natural+Science+Museum&swp=off) ![Color Factory Houston Ticket](https://mediaim.expedia.com/localexpert/49250599/f83520e0-6114-496f-b8a5-ea3fc8acdf42.jpg?impolicy=resizecrop&rw=500&rh=280) ### Color Factory Houston Ticket 1h 30m 9.6/10 7 Viator reviews $29 includes taxes & fees per adult [](https://www.expedia.com/things-to-do/color-factory-houston-ticket.a49250599.activity-details?&rid=501256&location=Houston+Natural+Science+Museum&swp=off) ![Museum of Illusions Houston Admission Ticket](https://mediaim.expedia.com/localexpert/50942393/ad4a7d96-dec8-4744-9cbd-5911366f603f.jpg?impolicy=resizecrop&rw=500&rh=280) ### Museum of Illusions Houston Admission Ticket 1h 30m 8/10 4 Viator reviews $38 includes taxes & fees per adult [](https://www.expedia.com/things-to-do/museum-of-illusions-houston-admission-ticket.a50942393.activity-details?&rid=501256&location=Houston+Natural+Science+Museum&swp=off) ![Meow Wolf's Radio Tave in Houston](https://mediaim.expedia.com/localexpert/50057257/f7f8ac12-1ffb-4304-a291-ad80b262e5fb.jpg?impolicy=resizecrop&rw=500&rh=280) ### Meow Wolf's Radio Tave in Houston 5h 8/10 5 verified reviews Free cancellation available $38 includes taxes & fees per adult [](https://www.expedia.com/things-to-do/meow-wolfs-radio-tave-in-houston.a50057257.activity-details?&rid=501256&location=Houston+Natural+Science+Museum&swp=off) ![Houston Museum of Natural Science and Cockrell Butterfly Center](https://mediaim.expedia.com/localexpert/1341348/878b0b75-ba2c-4afe-975f-e4ac6e480cbc.jpg?impolicy=resizecrop&rw=500&rh=280) ### Houston Museum of Natural Science and Cockrell Butterfly Center 4h 9.2/10 46 Viator reviews Free cancellation available $36 includes taxes & fees per adult [](https://www.expedia.com/things-to-do/houston-museum-of-natural-science-and-cockrell-butterfly-center.a1341348.activity-details?&rid=501256&location=Houston+Natural+Science+Museum&swp=off) ![The Escape Game Houston: 60-Minute Adventures at The Galleria](https://mediaim.expedia.com/localexpert/4778527/d10e74ad-3ae5-4761-924d-0dc01a56fde6.jpg?impolicy=resizecrop&rw=500&rh=280) ### The Escape Game Houston: 60-Minute Adventures at The Galleria 1h 15m 8/10 6 Viator reviews Free cancellation available $43 includes taxes & fees per adult [](https://www.expedia.com/things-to-do/the-escape-game-houston-60-minute-adventures-at-the-galleria.a4778527.activity-details?&rid=501256&location=Houston+Natural+Science+Museum&swp=off) ![Houston: 1-Hour Escape Room Adventure](https://mediaim.expedia.com/localexpert/48103747/c7a52aa1-213a-46a9-a8e9-da5f501dd620.jpg?impolicy=resizecrop&rw=500&rh=280) ### Houston: 1-Hour Escape Room Adventure 1h 10/10 1 GetYourGuide review Free cancellation available $43 includes taxes & fees per adult [](https://www.expedia.com/things-to-do/houston-1-hour-escape-room-adventure.a48103747.activity-details?&rid=501256&location=Houston+Natural+Science+Museum&swp=off) ![Houston: Color Factory Houston General Admission Ticket](https://mediaim.expedia.com/localexpert/52046025/ef6878c1-d7cc-4664-9eff-dead1de50986.jpg?impolicy=resizecrop&rw=500&rh=280) ### Houston: Color Factory Houston General Admission Ticket 1h 30m 10/10 1 GetYourGuide review Free cancellation available $34 includes taxes & fees per adult [](https://www.expedia.com/things-to-do/houston-color-factory-houston-general-admission-ticket.a52046025.activity-details?&rid=501256&location=Houston+Natural+Science+Museum&swp=off) ![Balloon Museum Houston Admission](https://mediaim.expedia.com/localexpert/52287639/a473db1c-0119-472d-bcb1-a61567c7d8b9.jpg?impolicy=resizecrop&rw=500&rh=280) ### Balloon Museum Houston Admission 30m $45 includes taxes & fees per adult [](https://www.expedia.com/things-to-do/balloon-museum-houston-admission.a52287639.activity-details?&rid=501256&location=Houston+Natural+Science+Museum&swp=off) ### Wildlife & nature [See all 4 activities](https://expedia.com/things-to-do/search?&rid=501256&location=Houston+Natural+Science+Museum&filter.categories=WildlifeNature) ![From Houston: Crocodile Encounter Entry Ticket](https://mediaim.expedia.com/localexpert/49700169/eb0c6dc7-e1c2-4e15-8c1b-21b5935508bd.jpg?impolicy=resizecrop&rw=500&rh=280) ### From Houston: Crocodile Encounter Entry Ticket 10/10 1 GetYourGuide review Free cancellation available $22 includes taxes & fees per adult [](https://www.expedia.com/things-to-do/from-houston-crocodile-encounter-entry-ticket.a49700169.activity-details?&rid=501256&location=Houston+Natural+Science+Museum&swp=off) ![Houston: Buffalo Bayou Park Cistern History Tour](https://mediaim.expedia.com/localexpert/47724478/6e8e677c-dd57-4be4-8379-3b01d3577b3e.jpg?impolicy=resizecrop&rw=500&rh=280) ### Houston: Buffalo Bayou Park Cistern History Tour 30m 10/10 25 GetYourGuide reviews Free cancellation available $15 includes taxes & fees per adult [](https://www.expedia.com/things-to-do/houston-buffalo-bayou-park-cistern-history-tour.a47724478.activity-details?&rid=501256&location=Houston+Natural+Science+Museum&swp=off) ![Houston: Luce Bayou Kayaking Tour](https://mediaim.expedia.com/localexpert/52084196/dc90b044-5875-464a-abc4-82b39b0db537.jpg?impolicy=resizecrop&rw=500&rh=280) ### Houston: Luce Bayou Kayaking Tour 4h Free cancellation available $266 includes taxes & fees per adult [](https://www.expedia.com/things-to-do/houston-luce-bayou-kayaking-tour.a52084196.activity-details?&rid=501256&location=Houston+Natural+Science+Museum&swp=off) ![Sea Kayak Surfing Rough Water Workshop](https://mediaim.expedia.com/localexpert/51865799/2ddc1ce6-d6c3-4fdf-a5f4-9fb76cda7a9e.jpg?impolicy=resizecrop&rw=500&rh=280) ### Sea Kayak Surfing Rough Water Workshop 8h Free cancellation available $346 includes taxes & fees per adult [](https://www.expedia.com/things-to-do/sea-kayak-surfing-rough-water-workshop.a51865799.activity-details?&rid=501256&location=Houston+Natural+Science+Museum&swp=off) ### Popular places to visit ![Houston Museum of Fine Arts](https://images.trvl-media.com/place/501255/13079137-af40-4d39-9d48-1cec8dd90a67.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Houston Museum of Fine Arts 4.5/5(236 reviews) Architecturally stunning and filled with pieces by renowned artists of the world, this museum is a must-see for art lovers. [](https://expedia.com/Houston-Museum-Of-Fine-Arts-South-Central-Houston.d501255.Vacation-Attraction) ![Children's Museum of Houston](https://images.trvl-media.com/place/1503/96c11d98-39b2-41f9-b570-bdc68afb4888.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Children's Museum of Houston 4.5/5(389 reviews) You can take time to visit Children's Museum of Houston during your travels to Houston. Experience the area's acclaimed art scene and great live music. [](https://expedia.com/Childrens-Museum-Of-Houston-South-Central-Houston.d6082211.Vacation-Attraction) ![Houston Contemporary Arts Museum](https://images.trvl-media.com/place/1503/c64aa0b3-f92b-4727-bd76-ff291e0a7753.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Houston Contemporary Arts Museum You can spend time browsing the exhibits at Houston Contemporary Arts Museum in Houston. Experience the area's acclaimed art scene and fascinating museums. [](https://expedia.com/Houston-Contemporary-Arts-Museum-South-Central-Houston.d501252.Vacation-Attraction) ![Hermann Park](https://images.trvl-media.com/place/507227/8b93533f-3cb9-4387-93ba-9714c57c3fb6.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Hermann Park 5/5(7 reviews) This expansive green space in the heart of the city offers places for exercising and relaxing, as well as a zoo and the Museum of Natural Science. [](https://expedia.com/Hermann-Park-South-Central-Houston.d507227.Vacation-Attraction) ![Houston Zoo](https://images.trvl-media.com/place/6082223/4aa2a7c3-abd4-427b-9029-5d992410e1c3.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Houston Zoo 4.5/5(1,018 reviews) Feed a giraffe, catch a 4-D movie or cool off in the water park at this extraordinary zoo. [](https://expedia.com/Houston-Zoo-South-Central-Houston.d6082223.Vacation-Attraction) ![Rice University in Houston, Texas](https://images.trvl-media.com/place/501268/a41362fa-e6d4-492a-b448-4229167d03cd.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Rice University 4.5/5(361 reviews) Enjoy the collegiate vibe when you visit Rice University, during your travels in Houston. Experience the area's lively festivals and fascinating museums. [](https://expedia.com/Rice-University-South-Central-Houston.d501268.Vacation-Attraction) --- ## Best Lodging Options Near Houston Natural Science Museum ## Check availability on hotels close to Houston Natural Science Museum [Tonight ](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=501256&startDate=2026-03-26&endDate=2026-03-27)[Mar 26 - Mar 27](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=501256&startDate=2026-03-26&endDate=2026-03-27) [Tomorrow night ](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=501256&startDate=2026-03-27&endDate=2026-03-28)[Mar 27 - Mar 28](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=501256&startDate=2026-03-27&endDate=2026-03-28) [This weekend ](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=501256&startDate=3%2F27%2F2026&endDate=3%2F29%2F2026)[Mar 27 - Mar 29](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=501256&startDate=3%2F27%2F2026&endDate=3%2F29%2F2026) [Next weekend ](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=501256&startDate=4%2F3%2F2026&endDate=4%2F5%2F2026)[Apr 3 - Apr 5](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=501256&startDate=4%2F3%2F2026&endDate=4%2F5%2F2026) ![Hotel Zaza Houston Museum District](https://images.trvl-media.com/lodging/1000000/10000/3400/3306/0f950f88_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hotel Zaza Houston Museum District 5701 Main Street Houston TX [](https://expedia.com/Houston-Hotels-Hotel-Zaza-Houston-Museum-District.h3306.Hotel-Information) ![Hilton Houston Plaza/Medical Center](https://images.trvl-media.com/lodging/1000000/30000/25200/25188/77443f8e_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hilton Houston Plaza/Medical Center 6633 Travis St Houston TX [](https://expedia.com/Houston-Hotels-Hilton-Houston-Plaza-Medical-Center.h25188.Hotel-Information) ![Blossom Hotel Houston, Curio Collection by Hilton](https://images.trvl-media.com/lodging/59000000/58990000/58985900/58985846/w3837h2505x3y0-1cfabad9_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Blossom Hotel Houston, Curio Collection by Hilton 7118 Bertner Ave Houston TX [](https://expedia.com/Houston-Hotels-Blossom-Hotel-Houston.h58985846.Hotel-Information) ![Americas Best Value Inn Medical Center Downtown](https://images.trvl-media.com/lodging/5000000/4110000/4100300/4100218/d27297d7_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Americas Best Value Inn Medical Center Downtown 2419 Riverside Dr Houston TX [](https://expedia.com/Houston-Hotels-Americas-Best-Value-Inn-Medical-Center-Downtown.h4100218.Hotel-Information) ![The Westin Houston Medical Center/Museum District](https://images.trvl-media.com/lodging/40000000/39620000/39618700/39618635/a994a387_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### The Westin Houston Medical Center/Museum District 1709 DRYDEN ROAD Houston TX [](https://expedia.com/Houston-Hotels-The-Westin-Houston-Medical-Center.h39618635.Hotel-Information) ![Houston Towers Inn Downtown Museum District Med. Ctr NRG - Adults Only](https://images.trvl-media.com/lodging/21000000/20060000/20052300/20052267/dd39b10f_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Houston Towers Inn Downtown Museum District Med. Ctr NRG - Adults Only 2309 Wichita St. Houston TX [](https://expedia.com/Houston-Hotels-Houston-Towers-Inn-Downtown-Museum-District-Med-Ctr-NRG-Adults-Only.h20052267.Hotel-Information) ![Houston Marriott Medical Center/Museum District](https://images.trvl-media.com/lodging/1000000/20000/16200/16154/647bab8d_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Houston Marriott Medical Center/Museum District 6580 Fannin Street Houston TX [](https://expedia.com/Houston-Hotels-Houston-Marriott-Medical-CenterMuseum-District.h16154.Hotel-Information) ![InterContinental Houston by IHG](https://images.trvl-media.com/lodging/24000000/23840000/23830900/23830866/2ea79db9_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### InterContinental Houston by IHG 6750 Main St Houston TX [](https://expedia.com/Houston-Hotels-InterContinental-Houston-Medical-Center.h23830866.Hotel-Information) ![DoubleTree by Hilton Houston Medical Center Hotel & Suites](https://images.trvl-media.com/lodging/1000000/10000/6700/6636/w3830h2557x6y0-b53d88b4_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### DoubleTree by Hilton Houston Medical Center Hotel & Suites 6800 Main Street Houston TX [](https://expedia.com/Houston-Hotels-Wyndham-Houston-Medical-Center-Hotel-And-Suites.h6636.Hotel-Information) [See all 5,316 properties in Houston Natural Science Museum](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Package®ionId=501256) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - [Houston Hotels ](https://www.expedia.com/Houston-Hotels.d178265.Travel-Guide-Hotels) - [Hotels near Downtown Houston ](https://www.expedia.com/Downtown-Houston-Houston-Hotels.0-n800037-0.Travel-Guide-Filter-Hotels) - [Cheap Hotels in Houston ](https://www.expedia.com/Houston-Hotels-Cheap-Hotels.0-0-d178265-tCheapHotels.Travel-Guide-Filter-Hotels) - [Hotels near MD Anderson Cancer Center ](https://www.expedia.com/MD-Anderson-Cancer-Center-Hotels.0-l6248539-0.Travel-Guide-Filter-Hotels) - [Hotels near Museum District ](https://www.expedia.com/Houston-Museum-District-Houston-Hotels.0-n6164045-0.Travel-Guide-Filter-Hotels) - [Pet-Friendly Hotels in Museum District ](https://www.expedia.com/Houston-Museum-District-Houston-Hotels-Pet-Friendly-Hotel.0-n6164045-0-tPetfriendlyHotel.Travel-Guide-Filter-Hotels) - [B&B in Museum District Station ](https://www.expedia.com/Museum-District-Station-Bed-And-Breakfast.d6211664-aaBedAndBreakfast.Travel-Guide-Accommodation) - 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