A calm river surrounded by trees with Spanish moss, reflecting the clear blue sky.

Mayo Vacation Rentals

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Check prices for these dates

In two weeks
Oct 9 - Oct 11
In two months
Nov 20 - Nov 22
In three months
Dec 18 - Dec 20
In four months
Jan 15 - Jan 17

Our top choices for Mayo vacation rentals

A wooden staircase leading to a riverbank with a view of the water and surrounding trees.

1. The Best memories are made on the Suwannee River

The Best memories are made on the Suwannee River
Mayo
9.8 out of 10, Exceptional, (58 reviews)
"Was there for a family reunion and was great for what we needed."
United States
Anonymous traveler
$228 nightly
The price is $243
Oct 1 - Oct 2
Total with taxes and fees
The Best memories are made on the Suwannee River
A wooden staircase leading to a dock over a calm body of water.

2. Beautiful memories are made on the Suwannee River in Mayo Fl

Beautiful memories are made on the Suwannee River in Mayo Fl
Mayo
$255 nightly
The price is $271
Sep 28 - Sep 29
Total with taxes and fees
Beautiful memories are made on the Suwannee River in Mayo Fl
A wooden deck with two benches and a table, surrounded by a wooden fence and trees.

3. SpringHouse at Convict Springs

SpringHouse at Convict Springs
Mayo
10.0 out of 10, Exceptional, (1 review)
$130 nightly
The price is $138
Sep 28 - Sep 29
Total with taxes and fees
SpringHouse at Convict Springs
A compact RV interior with a kitchenette, a bed, and a seating area.

4. RV with 1full bed 2twin beds and AC WiFi smart TV bathroom outdoor shower house

RV with 1full bed 2twin beds and AC WiFi smart TV bathroom outdoor shower house
Mayo
9.6 out of 10, Exceptional, (7 reviews)
"Love this little slice of heaven!"
United States
Crystal
$67 nightly
The price is $70
Sep 28 - Sep 29
Total with taxes and fees
RV with 1full bed 2twin beds and AC WiFi smart TV bathroom outdoor shower house
A wooden deck with a table and chairs, large windows, and a ceiling light.

5. The Chalet On the Suwannee River

The Chalet On the Suwannee River
Mayo
10.0 out of 10, Exceptional, (1 review)
"We were in the area to check out some local spring and loved the accessibility of this VRBO’s location. This property was amazing and super fun. Can’t wait to go back."
United States
Mandy B.
$245 nightly
The price is $261
Sep 28 - Sep 29
Total with taxes and fees
The Chalet On the Suwannee River
A compact kitchen with wooden cabinets, a microwave, and a sink.

6. Friendly's river retreat #1 cozy couples cabin in awesome Mayo with WiFi,

Friendly's river retreat #1 cozy couples cabin in awesome Mayo with WiFi,
Mayo
9.6 out of 10, Exceptional, (19 reviews)
"Fantastic property very quiet with very friendly animals."
United States
Hevrard
$91 nightly
The price is $96
Sep 29 - Sep 30
Total with taxes and fees
Friendly's river retreat #1 cozy couples cabin in awesome Mayo with WiFi,
Two wooden cabins with porches, one with a red exterior and the other with a brown exterior, surrounded by trees and grassy ground.

7. Friendlys River Retreat private Rustic Camping Cabin sleeps 4+with tent camping

Friendlys River Retreat private Rustic Camping Cabin sleeps 4+with tent camping
Mayo
9.4 out of 10, Exceptional, (17 reviews)
"Fantastic stay and amazing property owner. They were accommodating and helpful. Very glad I choose to stay here. I needed it to complete a job for a client and wasn’t expecting such a cool place to unwind after a hard days work. Two big thumbs up!"
United States
Blake
$91 nightly
The price is $96
Sep 29 - Sep 30
Total with taxes and fees
Friendlys River Retreat private Rustic Camping Cabin sleeps 4+with tent camping
A covered outdoor dining area with a table and chairs, large windows, and a view of greenery.

8. A-frame on the Suwannee River Rendezvous

A-frame on the Suwannee River Rendezvous
Mayo
6.0 out of 10, (1 review)
"Overnight night enroute"
Canada
Doug M.
$255 nightly
The price is $271
Sep 28 - Sep 29
Total with taxes and fees
A-frame on the Suwannee River Rendezvous
A covered porch with wooden railings, a table, and four chairs.

9. Suwannee Music Park about 30 mins away. Royal Springs across the street.

Suwannee Music Park about 30 mins away. Royal Springs across the street.
O'Brien
9.6 out of 10, Exceptional, (7 reviews)
"Ideal for weekend getaways, a quiet place to forget about the stress of the city, the house is so cozy. "
Mexico
Maria Josefina
$257 nightly
The price is $280
Oct 4 - Oct 5
Total with taxes and fees
Suwannee Music Park about 30 mins away. Royal Springs across the street.
A garden with a small pond, surrounded by various plants and a wooden structure.

10. Kokomo Farms - Cozy Cottage on the Farm

Kokomo Farms - Cozy Cottage on the Farm
Live Oak
9.8 out of 10, Exceptional, (15 reviews)
"Great place for nature!"
United States
Stephen
$154 nightly
The price is $167
Sep 28 - Sep 29
Total with taxes and fees
Kokomo Farms - Cozy Cottage on the Farm
A compact, well-lit room with a bed, a small sink, a potted plant, and a window with a view of the outdoors.

11. The Happy House Tiny Guest House

The Happy House Tiny Guest House
Live Oak
8.6 out of 10, Excellent, (8 reviews)
"very nice tiny house style accommodation"
United States
Cara B.
$134 nightly
The price is $145
Sep 28 - Sep 29
Total with taxes and fees
The Happy House Tiny Guest House

12. Cozy Lake House, Hot Tub & Close to FL Springs

Cozy Lake House, Hot Tub & Close to FL Springs
Branford
10.0 out of 10, Exceptional, (1 review)
"Juan was so welcoming. The house was clean and had everything we needed for a fun family getaway - and then some! Would love to stay here again. "
United States
Ashley L.
$245 nightly
The price is $261
Oct 5 - Oct 6
Total with taxes and fees
Cozy Lake House, Hot Tub & Close to FL Springs

13. Nook at the Springs | Tiny Home • Full Kitchen

Nook at the Springs | Tiny Home • Full Kitchen
Fort White
9.8 out of 10, Exceptional, (9 reviews)
"Excellent place "
United States
Linay
$154 nightly
The price is $166
Sep 28 - Sep 29
Total with taxes and fees
Nook at the Springs | Tiny Home • Full Kitchen
A room with a ceiling fan, a dining table with chairs, a patterned rug, and large windows with curtains.

14. Peaceful 3BR/2BA Near Suwannee River & Springs

Peaceful 3BR/2BA Near Suwannee River & Springs
Live Oak
10.0 out of 10, Exceptional, (1 review)
$147 nightly
The price is $159
Oct 3 - Oct 4
Total with taxes and fees
Peaceful 3BR/2BA Near Suwannee River & Springs
A covered outdoor seating area with wicker chairs and a table, surrounded by a wooden deck and railing.

15. Rustic River Cabin 2-bedroom cabin in Branford near Santa Fe River

Rustic River Cabin 2-bedroom cabin in Branford near Santa Fe River
Branford
10.0 out of 10, Exceptional, (12 reviews)
"Hosts are awesome, and there's enough amenities to keep any family busy for as long as they'd like. "
United States
James S.
$216 nightly
The price is $236
Sep 29 - Sep 30
Total with taxes and fees
Rustic River Cabin 2-bedroom cabin in Branford near Santa Fe River
A covered outdoor seating area with a round wooden table, white wicker chairs, and a black grill.

16. < 1 Mi From Suwannee River, Hideaway w/ Lanai

< 1 Mi From Suwannee River, Hideaway w/ Lanai
3.0 star property
Old Town
9.0 out of 10, Wonderful, (2 reviews)
"The Air B & B was amazing. The property and the A B & B was awesone, Clean, Quiet and very comfortable. Although some nights got a bit chilly and this property only had AC no heat. We managed just fine. We left it in perfect conditions according to the directions they wanted it left in. Thank you so much and we will be renting again. We also would recommend this to others. "
United States
Karen
$352 nightly
The price is $387
Sep 28 - Sep 29
Total with taxes and fees
< 1 Mi From Suwannee River, Hideaway w/ Lanai
A compact RV interior with a kitchenette, a bed with a blue bedspread, a dining area with stools, and a ceiling fan.

17. The Sea Shed

The Sea Shed
Perry
10.0 out of 10, Exceptional, (14 reviews)
"The Sea Shack was perfect for my husband and I to stay while visiting family."
United States
Sheila
$151 nightly
The price is $167
Sep 28 - Sep 29
Total with taxes and fees
The Sea Shed
A kitchen with wooden cabinets, a stainless steel refrigerator, and a window overlooking greenery.

18. The Loft Private Cabin Near Hulaween & Spirit of the Suwannee

The Loft Private Cabin Near Hulaween & Spirit of the Suwannee
Live Oak
10.0 out of 10, Exceptional, (36 reviews)
"Fantastic place, super clean and dreamy! We had an amazing stay"
United States
Maria C.
$161 nightly
The price is $175
Oct 5 - Oct 6
Total with taxes and fees
The Loft Private Cabin Near Hulaween & Spirit of the Suwannee
A two-story house with a porch, surrounded by trees and a body of water.

19. Beautiful 2 story house overlooking the water. Has arcade & Close to the springs

Beautiful 2 story house overlooking the water. Has arcade & Close to the springs
Live Oak
10.0 out of 10, Exceptional, (82 reviews)
"Nice place to stay with kids. Pond in the back has excellent catch and release fishing. Host very responsive. We will stay here again."
United States
Justin T Kirksey K.
$229 nightly
The price is $250
Oct 4 - Oct 5
Total with taxes and fees
Beautiful 2 story house overlooking the water. Has arcade & Close to the springs
A compact RV interior with a kitchenette, a seating area, and a television.

20. The Holy Mackerel Family and pet friendly

The Holy Mackerel Family and pet friendly
Perry
9.8 out of 10, Exceptional, (15 reviews)
"Perfect location, nice comfortable stay with incredible host!!"
United States
Brian
$155 nightly
The price is $171
Sep 28 - Sep 29
Total with taxes and fees
The Holy Mackerel Family and pet friendly
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Mayo Hotel Reviews

Royal Inn Motel

Royal Inn Motel

10/10 Excellent
"Second time to stay there in the past two years."
Ricky F 1-night trip
Posted 4 hours ago
Royal Inn Motel

Find out more about Mayo

Everything you need to know about Mayo vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Mayo vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Mayo vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Mayo vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Mayo. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Mayo in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $96 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on Mayo rentals

At Expedia, we put the best Mayo vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Mayo rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Mayo vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Mayo. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Explore a world of travel with Expedia

Frequently asked questions

Are there vacation rentals in Mayo?

Yes, we offer vacation rentals in Mayo close to Veteran's Memorial Park of Mayo, or you can select a more remote option if you're looking for a relaxing stay. Mayo is known for its parks.

What are some of the best vacation rentals that Mayo has to offer?

ICHETUCKNEE RIVER - Riverfront on the Crystal Clear Ichetucknee River: This vacation home rental outside of Mayo is located on a river and has a balcony, a garden, and a barbecue grill to put you at ease in your new surroundings. It has 4 bedrooms as well as a kitchen with a fridge, a stovetop, and a microwave, so you can cook with friends or family.

How many vacation rentals are there in Mayo?

Expedia has 7 vacation rentals for your stay in Mayo.

What can I see and do in Mayo?

Family-friendly attractions include Veteran's Memorial Park of Mayo, whereas Suwannee River is a spot to enjoy the outdoors. Other places in town to visit include Lafayette Blue Springs State Park and Lafayette County Library.

What are vacation rentals like in Mayo?

Vacation rentals are privately owned accommodations you can reserve for a short or long stay in Mayo. Vacation rentals feature amenities such as patios, hot tubs, and fire pits so you'll feel right at home. If you're concerned about cleanliness, vacation rentals can offer a sense of privacy away from shared hotel elevators and lobbies bustling with people while still allowing you to travel. You'll also get more space in a vacation rental than in a traditional hotel, which makes a vacation rental a popular option for a small group gathering.