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O Brien Vacation Rentals

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Vacation Rentals in O Brien

Royal Springs Riverfront Retreat on 3 acres, kayak/canoe, boat ramp, huge decks!

obrien
9.8 out of 10, Exceptional, (28)
"Great spot for getting away from it all"
United States
Derek C.
Royal Springs Riverfront Retreat on 3 acres, kayak/canoe, boat ramp, huge decks!

MARGARITAVILLE BY THE SUWANNEE RIVER & ROYAL SPRINGS PET FRIENDLY

O'Brien
9.4 out of 10, Exceptional, (59)
"Great rental for our family, including our dogs, to relax and enjoy the outdoors. Loved the decks and visiting nearby parks. Appreciated the responsiveness and hospitality of our hosts."
United States
Pam M.
$370 nightly
The price is $402
Nov 16 - Nov 17
Total with taxes and fees
MARGARITAVILLE BY THE SUWANNEE RIVER & ROYAL SPRINGS PET FRIENDLY

Postcard Cabins Gilchrest Spring, Outdoor Collection by Marriott Bonvoy

2.0 star property
High Springs
9.8 out of 10, Exceptional, (136)
"Amazing getaway ,, I love the amenities and the firewood and everything was amazing great service perfect escape from reality."
United States
Emperesse
$149 nightly
The price is $164
Nov 18 - Nov 19
Total with taxes and fees
Postcard Cabins Gilchrest Spring, Outdoor Collection by Marriott Bonvoy

Walking distance to Brewery and Restaurants ⭐️⭐️⭐️⭐️⭐️

High Springs
9.8 out of 10, Exceptional, (52)
"house was perfect for our trip and location was ideal. thank you! "
United States
Laura L.
$245 nightly
The price is $272
Nov 30 - Dec 1
Total with taxes and fees
Walking distance to Brewery and Restaurants ⭐️⭐️⭐️⭐️⭐️

Private, 1 Mile to Poe, 4 miles to Blue, 6 Miles to Ginnie. Tent/Camper camping

High Springs
10.0 out of 10, Exceptional, (2)
"The host's were very friendly and available. The property is in a great location and easily accessible to many natural attractions. The main road has a nice bike / walking path towards town. This is a typical farm / country setting that is comfortable. There are no extravagant furnishings, just a nice back yard, fire pit and rod iron lawn furniture with cushions. The above ground pool was welcoming but not ideal for getting in and out of at our age. There is a small bathroom with a shower...
United States
Laura
$57 nightly
The price is $61
Nov 15 - Nov 16
Total with taxes and fees
Private, 1 Mile to Poe, 4 miles to Blue, 6 Miles to Ginnie. Tent/Camper camping

3-bedroom house in gorgeous Lake City with WiFi, AC and country comfort

Lake City
9.4 out of 10, Exceptional, (3)
"This stay was perfect for our group's case. A group of 3 of us were headed south to Gainesville for Florida's Homecoming and needed a place to sleep and shower after a 7.5 hour drive. We did not spend a lot of time here, but the host was very communicative, the place was clean, stocked with amenities for guests, and the host even welcomed us with gift bags themed towards football, which I shared was the reason we were coming beforehand. It was wholesome and thoughtful. The structure overall is...
United States
Travis B.
3-bedroom house in gorgeous Lake City with WiFi, AC and country comfort

Enjoy semi-seclusion on the beautiful Suwannee River

White Springs
10.0 out of 10, Exceptional, (48)
"Great place to spend a weekend"
United States
Brad C.
Enjoy semi-seclusion on the beautiful Suwannee River

Suwannee Comfort, Private Cozy Cabin on the Suwannee River

2.0 star property
White Springs
10.0 out of 10, Exceptional, (12)
"Spent a night here before our river excursion. Great place "
United States
sean i.
Suwannee Comfort, Private Cozy Cabin on the Suwannee River

ICHETUCKNEE RIVER - Riverfront on the Crystal Clear Ichetucknee River

Fort White,
9.8 out of 10, Exceptional, (102)
"We love it here. We come every summer."
United States
Izabel L.
ICHETUCKNEE RIVER - Riverfront on the Crystal Clear Ichetucknee River

Bunkhouse Farm Stay

Fort White
10.0 out of 10, Exceptional, (150)
"Our second visit to this location. We'll be back!"
United States
Jill F.
Bunkhouse Farm Stay

Cozy Log Cabin Retreat on the Santa Fe River – Nature, Kayaking & Relaxation!

Branford
10.0 out of 10, Exceptional, (9)
" Rustic Comfort on the Santa Fe RiverWe had a fantastic stay at this rustic but incredibly comfortable cabin right on the Santa Fe River. There was plenty of room for our group of 8, and the kids spent most of their time fishing off the dock in the backyard or kayaking along the river. The host provided kayaks, floats, and fishing poles, which made it so easy to jump right into the fun.The kitchen was well-appointed with everything we needed, and the beds were very comfortable. The location is...
United States
Tina B.
Cozy Log Cabin Retreat on the Santa Fe River – Nature, Kayaking & Relaxation!

Friendlys River Retreat private Rustic Camping Cabin sleeps 4+with tent camping

Mayo
10.0 out of 10, Exceptional, (7)
"This was such a serene and peaceful stay! Stacey was amazing and so kind! Soooo many springs around and the amazing Suwanee River!! "
United States
Crystal
$73 nightly
The price is $77
Nov 17 - Nov 18
Total with taxes and fees
Friendlys River Retreat private Rustic Camping Cabin sleeps 4+with tent camping

Cabin on Sante Fe Inlet in Three River Estates (walking distance to park)

Fort White
9.2 out of 10, Wonderful, (104)
"We enjoyed our stay so much we added an extra day. Cabin is dated but cozy, in fact I kind of like it like that because I felt like I transported back to the 90s. Awesome location in the woods, lots of wildlife and a great area outside to grill and enjoy a fire. "
United States
Margaret
Cabin on Sante Fe Inlet in Three River Estates (walking distance to park)

O'LE LADYBUG COTTAGE

Lake City
9.6 out of 10, Exceptional, (49)
"Great location for kayaking."
United States
Meg L.
$189 nightly
The price is $210
Nov 15 - Nov 16
Total with taxes and fees
O'LE LADYBUG COTTAGE

Welcome to "The Red Hideaway"!

Live Oak
8.8 out of 10, Excellent, (9)
"Kids playground in short walking distance. Restaurants and stores all right around the corner"
United States
Felicia S.
Welcome to "The Red Hideaway"!

Cozy house near famous springs and town

High Springs
9.2 out of 10, Wonderful, (27)
"Staff allowed early check in. Place was near the springs and we saw 4 deer in the front yard one fall morning! We'll be back!"
United States
Mission Fishin Lures
Cozy house near famous springs and town

Serenity Springs On The Suwannee Tree House #1

Old Town
9.8 out of 10, Exceptional, (8)
"This cabin is absolutely wonderful. Can hear the owls, fish jumping, out in nature for sure. Very clean, comfy beds, beautiful view of the Suwanee river. "
United States
Hazel L.
Serenity Springs On The Suwannee Tree House #1

Beautiful cozy cottage fully fenced near town and springs

High Springs
9.4 out of 10, Exceptional, (29)
"we loved our stay here. Perfect location and convenient to the wedding venue. Clean and tastefully decorated. Host were very attentive and very friendly. Would definitely recommend this place to anyone looking for something nearby. "
United States
Donna P.
$251 nightly
The price is $279
Nov 16 - Nov 17
Total with taxes and fees
Beautiful cozy cottage fully fenced near town and springs

Private&Secluded Getaway, near I-75,town, parks,Springs. Glamping ,low key style

Lake City
8.2 out of 10, Very Good, (50)
"Was a great experience. Very quiet and hassle free. Just what we needed."
United States
Kenneth D.
$157 nightly
The price is $174
Nov 15 - Nov 16
Total with taxes and fees
Private&Secluded Getaway, near I-75,town, parks,Springs. Glamping ,low key style

Peaceful Cabin Getaway • Live Oak, FL

Live Oak
10.0 out of 10, Exceptional, (17)
"Private and secluded getaway spot that was a perfect comfortable and cozy retreat after my long and busy days! Space was very clean and hosts were incredibly responsive and hospitable, going above and beyond to make sure I had everything I needed."
United States
Vanessa
$116 nightly
The price is $125
Dec 1 - Dec 2
Total with taxes and fees
Peaceful Cabin Getaway • Live Oak, FL
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top O Brien Hotel Reviews

Find out more about O Brien

Everything you need to know about O Brien vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the O Brien vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect O Brien vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

O Brien vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in O Brien. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit O Brien in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $61 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on O Brien rentals

At Expedia, we put the best O Brien vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top O Brien rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream O Brien vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around O Brien. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Frequently asked questions

Can I find a vacation rental in O Brien?

Yes, we offer vacation rentals close to well known points of interest in O Brien, or you can go with a more secluded option if you're looking for a relaxing stay.

What's the top vacation rental that O Brien has to offer?

Royal Springs Riverfront Retreat on 3 acres, kayak/canoe, boat ramp, huge decks!: Visitors like this O Brien vacation home rental. It is located on the beach and has a balcony, a garden, and a barbecue grill to put you at ease in your new surroundings. It has 3 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. You and your friends and family can relax into your vacation with amenities like a selection of games.

How many vacation rentals are there in O Brien?

Expedia has 6 vacation rentals for your stay in O Brien.

What’s there to see and do in O Brien?

Suwannee River and Ichetucknee River are a couple of lovely local spots to get outside and enjoy nature. Ichetucknee Springs State Park and Wes Skiles Peacock Springs State Park are a couple of places you'll find in the larger area.

What’s a vacation rental in O Brien like?

Vacation rentals are private properties you can stay in for several days or longer in O Brien. Vacation rentals offer amenities like WiFi and washers and dryers so you'll have everything you need. If you're concerned about a sanitized environment, a vacation rental can offer a sense of privacy away from public hotel elevators and bustling concierge desks while still allowing you the excitement and enjoyment of travel. You'll also have more space in a vacation rental than in a standard hotel, which is another reason why a vacation rental is a popular choice for small groups.