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Our top choices for O Brien hotels

Holiday Inn Express & Suites Alachua - Gainesville Area by IHG

Holiday Inn Express & Suites Alachua - Gainesville Area by IHG
3.5 star property
Alachua
9.4 out of 10, Exceptional, (1,014 reviews)
"Rooms were clean and spacious. The kids enjoyed the pool, hot tub and breakfast. I will stay here again if we are in the area."
United States
Brandi
$104 nightly
The price is $117
May 17 - May 18
Total with taxes and fees
Holiday Inn Express & Suites Alachua - Gainesville Area by IHG

La Quinta Inn & Suite by Wyndham Lake City

La Quinta Inn & Suite by Wyndham Lake City
2.5 star property
Lake City
8.8 out of 10, Excellent, (1,109 reviews)
"Nice hotel, nice price - recommend."
United States
Michael D
$102 nightly
The price is $114
May 31 - Jun 1
Total with taxes and fees
La Quinta Inn & Suite by Wyndham Lake City

Best Western Plus Lake City

Best Western Plus Lake City
2.5 star property
Lake City
9.0 out of 10, Wonderful, (1,062 reviews)
"Great staff, good room, lovely breakfast"
United States
berendina
$99 nightly
The price is $111
May 17 - May 18
Total with taxes and fees
Best Western Plus Lake City

Tru by Hilton Lake City

Tru by Hilton Lake City
2.5 star property
Lake City
9.2 out of 10, Wonderful, (1,010 reviews)
"Very clean and a great place to stay!"
United States
Charika
$109 nightly
The price is $123
Jun 7 - Jun 8
Total with taxes and fees
Tru by Hilton Lake City

Home2 Suites by Hilton Lake City

Home2 Suites by Hilton Lake City
3.0 star property
Lake City
9.4 out of 10, Exceptional, (787 reviews)
"Great place to stay we will be back soon. "
United States
William
$132 nightly
The price is $149
May 17 - May 18
Total with taxes and fees
Home2 Suites by Hilton Lake City

Holiday Inn & Suites Lake City by IHG

Holiday Inn & Suites Lake City by IHG
3.0 star property
Lake City
8.6 out of 10, Excellent, (1,000 reviews)
"My stay was relaxing and peaceful "
United States
Kevin
$114 nightly
The price is $128
May 17 - May 18
Total with taxes and fees
Holiday Inn & Suites Lake City by IHG

Suwannee River Rendezvous

Suwannee River Rendezvous
2.5 star property
Mayo
8.6 out of 10, Excellent, (28 reviews)
"Staff was very helpful and attentive room was great great location "
United States
Madeline
$40 nightly
The price is $43
May 18 - May 19
Total with taxes and fees
Suwannee River Rendezvous

Courtyard By Marriott Lake City

Courtyard By Marriott Lake City
3.0 star property
Lake City
9.4 out of 10, Exceptional, (252 reviews)
"Clean hotel, nice room, good value."
United States
Danielle
$116 nightly
The price is $131
May 24 - May 25
Total with taxes and fees
Courtyard By Marriott Lake City

Americas Best Value Inn Lake City

Americas Best Value Inn Lake City
2.0 star property
Lake City
8.6 out of 10, Excellent, (1,000 reviews)
"The staff was very nice and polite and it's very simple to get in."
United States
Ricardo
$66 nightly
The price is $74
May 26 - May 27
Total with taxes and fees
Americas Best Value Inn Lake City

Holiday Inn Express & Suites Live Oak by IHG

Holiday Inn Express & Suites Live Oak by IHG
2.5 star property
Live Oak
8.4 out of 10, Very Good, (831 reviews)
"Great stay!"
United States
Wes
$131 nightly
The price is $144
May 17 - May 18
Total with taxes and fees
Holiday Inn Express & Suites Live Oak by IHG

Hampton Inn & Suites Lake City

Hampton Inn & Suites Lake City
2.5 star property
Lake City
9.4 out of 10, Exceptional, (1,001 reviews)
"Breakfast menu was fresh, the room was clean, and the staff friendly and professional."
United States
Claire
$144 nightly
The price is $162
May 17 - May 18
Total with taxes and fees
Hampton Inn & Suites Lake City

Comfort Suites Lake City

Comfort Suites Lake City
2.5 star property
Lake City
9.4 out of 10, Exceptional, (1,010 reviews)
"The staff was very nice, breakfast was good and they kept a watch on to replace any items that needed. The room was clean, the beds comfortable. We had a wonderful stay."
United States
Evelin
$117 nightly
The price is $131
May 19 - May 20
Total with taxes and fees
Comfort Suites Lake City

Fairfield Inn & Suites Lake City

Fairfield Inn & Suites Lake City
3.0 star property
Lake City
9.0 out of 10, Wonderful, (234 reviews)
"Excellent stay. Great breakfast. "
United States
Janet
$139 nightly
The price is $156
May 17 - May 18
Total with taxes and fees
Fairfield Inn & Suites Lake City

Quality Inn Alachua - Gainesville Area

Quality Inn Alachua - Gainesville Area
2.5 star property
Alachua
7.2 out of 10, Good, (1,015 reviews)
"Solid hotel for the price"
United States
Michael
$74 nightly
The price is $84
Jun 2 - Jun 3
Total with taxes and fees
Quality Inn Alachua - Gainesville Area

Hampton Inn & Suites Alachua I-75

Hampton Inn & Suites Alachua I-75
2.5 star property
Alachua
9.4 out of 10, Exceptional, (511 reviews)
"Room was very clean, breakfast was awesome, everything was good."
United States
James
$93 nightly
The price is $104
May 31 - Jun 1
Total with taxes and fees
Hampton Inn & Suites Alachua I-75

BlueGem Motel

BlueGem Motel
2.0 star property
High Springs
9.2 out of 10, Wonderful, (440 reviews)
"Wonderful staff nice location clean rooms"
United States
Wayne
$97 nightly
The price is $109
Jun 7 - Jun 8
Total with taxes and fees
BlueGem Motel

Quality Inn White Springs Suwanee

Quality Inn White Springs Suwanee
2.5 star property
Live Oak
7.2 out of 10, Good, (668 reviews)
"It's a great place to stay if you're going to a festival at the spirit of Suwanee music Park "
United States
Elizabeth
$72 nightly
The price is $79
Jun 2 - Jun 3
Total with taxes and fees
Quality Inn White Springs Suwanee

Palms Garden Inn

Palms Garden Inn
2.0 star property
Lake City
7.4 out of 10, Good, (606 reviews)
"Staff nice and helpful"
United States
Drew
$64 nightly
The price is $71
May 24 - May 25
Total with taxes and fees
Palms Garden Inn

Super 8 by Wyndham Lake City

Super 8 by Wyndham Lake City
2.0 star property
Lake City
7.4 out of 10, Good, (709 reviews)
"Great counters in the bathroom!! Loved the served breakfast and dinner!"
United States
Wendy
$62 nightly
The price is $70
Jun 7 - Jun 8
Total with taxes and fees
Super 8 by Wyndham Lake City

Quality Inn Lake City

Quality Inn Lake City
2.5 star property
Lake City
8.0 out of 10, Very Good, (1,008 reviews)
"Convenient to restaurants "
United States
Bruce
$75 nightly
The price is $85
Jun 7 - Jun 8
Total with taxes and fees
Quality Inn Lake City
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Where to stay near O Brien

O’Brien, Florida, offers a delightful escape for outdoor enthusiasts and adventure seekers. Explore the stunning scenery and family-friendly atmosphere in the surrounding areas, perfect for eco-friendly vacations and memorable adventures. Enjoy the charm of nature while creating lasting memories with loved ones.

Branford

Discover Branford, a charming destination perfect for families and nature enthusiasts seeking adventure and scenic beauty. With attractions like the Suwannee River for outdoor fun, Troy Spring State Park for exploration, and Sampson Lake for peaceful relaxation, there’s something for everyone. Located about 6 miles by car from O Brien, Branford offers easy access to a variety of recreational activities year-round, making it a smart choice for your vacation stay.

Mcalpin

Plan your stay in Mcalpin, a top-rated choice for families and nature enthusiasts looking for a delightful mix of outdoor adventure and scenic beauty. Explore the nearby Suwannee River, perfect for recreational activities, and discover wildlife at Troy Spring State Park, alongside the relaxing atmosphere of Baker Park. Located about 7 miles by car from O Brien, Mcalpin offers a strategic base to enjoy these attractions while providing a budget-friendly option for your vacation.

Alton

Make your vacation planning effortless by staying in Alton, a haven for nature and adventure enthusiasts thanks to its beautiful scenery and outdoor experiences. Explore the wonders of the nearby Wes Skiles Peacock Springs State Park, unwind at Veteran's Memorial Park of Mayo, or dive into a good book at the Lafayette County Library. Alton is located about 19 miles by car from O Brien, making it a smart choice for a memorable getaway.

Mayo

Immerse yourself in Mayo, where outdoor enthusiasts and families can easily access breathtaking natural beauty and adventure. This charming city is a gateway to Lafayette Blue Springs State Park, perfect for swimming and hiking, while Telford Spring offers refreshing river activities. With a variety of recreational areas nearby, Mayo is ideal for budget-conscious travelers seeking memorable experiences. Located about 14 miles by car from O Brien, Mayo is a smart choice for your next getaway.

Wellborn

Travelers seeking a family-friendly getaway will find Wellborn to be an ideal base for their vacation, featuring scenic outdoor experiences and budget-friendly options. Enjoy the charm of the Stephen Foster Folk Culture Center, explore the serene Blue Sink Canoe Launch, or delve into history at the Stephen Foster State Folk Center. Located about 15 miles by car from O Brien, Wellborn offers easy access to natural attractions like rivers and lakes, making it a smart choice for your stay.

Stay near popular attractions around O Brien

O'Brien is a hidden gem for travelers seeking outdoor adventures and stunning scenery. With its picturesque parks and tranquil rivers, you'll find endless opportunities for family fun and exploration. Experience the beauty and charm that make this area a perfect getaway for nature lovers.

Learn more about O Brien

Escape to this rural Florida gem where the Suwannee River offers peaceful kayaking trips and fishing adventures. Nearby Spirit of the Suwannee Music Park hosts live concerts, while O'Brien's local farms welcome visitors for fresh produce and family-friendly activities.

kayakers at Rock Bluff Spring on the Suwanneee River, Gilchrist County, Florida

Top O Brien Hotel Reviews

More cheap stays in O Brien

Hotels in O Brien with star-rating

Find out more about O Brien

Top reasons to visit O Brien

  • Outdoor Adventures: O'Brien is perfect for outdoor enthusiasts, offering activities like hiking, fishing, and exploring scenic parks.
  • Scenic Beauty: The area boasts stunning natural landscapes, including local rivers and tranquil nature trails.
  • Community Events: Experience a friendly atmosphere with vibrant community events and local culture.
  • Accommodations for Everyone: O'Brien has a range of welcoming accommodations, from pet-friendly motels to cozy hotels.
  • Family-Friendly Atmosphere: Ideal for families, O'Brien offers a mix of adventure and relaxation for all ages.

Find great hotels near O Brien

Discover a variety of welcoming accommodations in O'Brien, Florida, ideal for every traveler. Whether you’re seeking a pet-friendly motel or a cozy hotel for business travel, you'll find options that provide essential amenities like free Wi-Fi. Enjoy an inclusive atmosphere perfect for LGBTQIA travelers, and explore nearby Branford and Troy Street for additional lodging choices. Your perfect O'Brien getaway awaits.

  • Baymont by Wyndham Lake City I-75: Located 18 miles from O'Brien, Baymont by Wyndham Lake City I-75 offers a budget-friendly stay perfect for families and business travelers alike. This pet-friendly hotel provides a welcoming atmosphere with amenities tailored for children, including complimentary cribs. Guests can enjoy the convenience of bringing their furry friends along, with specific pet policies in place. The hotel fosters a family-oriented environment while ensuring comfort and accessibility for all guests.
  • Americas Best Value Inn Lake City: Just 18 miles from O'Brien, Americas Best Value Inn Lake City boasts a commendable guest rating of 8.6 out of 10. This budget-friendly motel is ideal for pet owners seeking a comfortable getaway. With a focus on affordability and convenience, the hotel permits pets onsite, alongside a waived fee for service animals. Visitors appreciate the warm hospitality and the straightforward amenities that make their stay enjoyable.
  • Comfort Suites Lake City: Situated 18 miles away from O'Brien, Comfort Suites Lake City is a highly rated hotel with an impressive score of 9.6 out of 10. This establishment caters primarily to business travelers, offering spacious suites equipped for productivity and relaxation. Guests can appreciate the well-appointed facilities and a commitment to quality service, ensuring a successful stay for those traveling for work or leisure.

Where to stay near O Brien

O'Brien, Florida, is a hidden gem perfect for outdoor enthusiasts and families alike. With stunning scenery and adventurous activities, you'll find plenty to explore in this charming city. Nearby attractions offer a friendly atmosphere, inviting travelers to enjoy nature trails, local parks, and vibrant community events. Whether you're looking to unwind or embark on an adventure, O'Brien and its surrounding areas promise a memorable vacation experience.

  • Branford: Located a mere 6 miles from O'Brien, Branford is a charming city that attracts visitors year-round, with peak traveler arrivals in April and June to July. This destination is perfect for outdoor enthusiasts and adventure seekers, offering a variety of recreational areas, underwater sports, and breathtaking scenery. You can explore the nearby national state park, meander along the serene river, or partake in exciting adventure activities. Branford's natural beauty and welcoming atmosphere make it a delightful stop for those looking to connect with nature and enjoy thrilling experiences.
  • Mcalpin: Situated 7 miles away from O'Brien, Mcalpin is another appealing city that sees moderate seasonal travel throughout the year, with visitor numbers peaking consistently. It’s an ideal location for those who love the great outdoors, featuring stunning landscapes and an array of adventure activities. Visitors can enjoy recreational areas and partake in underwater sports while discovering the nearby national state park and tranquil river settings. Mcalpin provides a perfect blend of adventure and relaxation, making it a great spot for family outings or solo explorations.
  • Mayo: Located 14 miles from O'Brien, Mayo is a picturesque city that welcomes visitors throughout the year, with peak seasons in March to April and September. Known for its outdoor adventures and scenic views, Mayo offers various recreational activities and underwater sports that thrill adventure seekers. The proximity to a national state park, lush parks, and the scenic river enhances your experience, inviting you to immerse yourself in nature’s splendor. Mayo's small-town charm and vibrant outdoor culture make it a must-visit destination for those looking to escape into nature.

Things to do in O Brien

O'Brien, Florida, is perfect for outdoor enthusiasts seeking adventure and scenic beauty. Popular activities include exploring recreational areas, engaging in underwater sports, and enjoying various adventure activities. It's an ideal destination for fishing enthusiasts and those looking for exciting Florida tours, making it a great spot for an unforgettable vacation filled with exploration and fun.

Shopping

In O'Brien, you can enjoy local shops offering unique souvenirs and gifts. If you're up for a drive, check out the nearby Lake City Mall, where you'll find a variety of retailers, from fashion to home goods, perfect for picking up memorable items from your trip.

Recreation

Experience tranquility at the Suwannee River Retreat, where you can unwind with yoga classes and nature walks along the serene riverbanks. For recreational fun, explore nearby parks for hiking and fishing, or enjoy a peaceful kayak ride on the beautiful waters.

Adventure

In O'Brien, explore the scenic beauty of the nearby Suwannee River, perfect for kayaking and fishing. Experience thrilling airboat rides through the wetlands, offering close encounters with unique wildlife. Don't miss the picturesque trails for hiking and biking, showcasing Florida's lush landscapes and diverse ecosystems.

Nightlife

In O'Brien, Florida, the nightlife is laid-back yet vibrant, featuring local bars and cozy venues. The O'Brien Community Center hosts events, while nearby spots offer live music and friendly gatherings, perfect for unwinding after a day of exploring the area's natural beauty.

*Distances are measured in a straight line; actual driving distances may vary depending on the route.

Booking tips and Expedia advantages for O Brien

  • The most and least expensive months on average to stay in a hotel: The cheapest months to stay in O Brien are January, August and November, where the prices are slightly lower. This is in comparison to March, May and October, where prices are slightly higher.
  • The most and least expensive days on average to stay in a hotel: The least expensive day to stay in O Brien is Monday. The most expensive day to stay in O Brien is Saturday.
  • Find cheap hotels on Expedia: Expedia's search tool lets you choose your budget, preferred location, and additional criteria. You can organize your results to display prices from lowest to highest, ensuring you see the most affordable hotels first. Additionally, you can refine your options by hotel type—if you select the Eco-certified filter, you'll find sustainable and eco-friendly hotels ready for booking.
  • Consider bundling your trip: You can save money by combining your O'Brien hotel reservation with your flights and activities through an Expedia package deal.

Find the best attractions near O Brien

O Brien, Florida, is an ideal destination for outdoor enthusiasts and adventure seekers. Visitors can explore scenic national and state parks, enjoy the beauty of local rivers, and visit the library for a taste of local culture. Whether you're looking for thrilling activities or peaceful scenery, O Brien offers a range of attractions that cater to all types of travelers seeking an unforgettable experience in the heart of Florida.

  • Suwannee River: Located 6 miles from O Brien, the Suwannee River offers stunning scenery and a serene outdoor experience. Perfect for kayaking, fishing, or simply enjoying nature's beauty, this river is a fantastic spot for relaxation and adventure.
  • Ichetucknee Springs State Park: Situated 11 miles away, this state park is a gem for outdoor enthusiasts. With lush landscapes, crystal-clear springs, and various recreational activities, you can enjoy tubing, snorkeling, or hiking while soaking up the vibrant scenery.
  • Ichetucknee River: Also located 11 miles from O Brien, the Ichetucknee River provides a picturesque setting for tubing and canoeing. Its tranquil waters and scenic surroundings make it an ideal destination for a leisurely day in nature.

Best time to go to O Brien

The best time to visit O Brien is dependent on what kind of holiday you are seeking. July is its hottest month on average. At this time, visitor numbers are moderately high and weather is mostly sunny with light rain. January is its coolest month on average. At this time, visitor numbers are average and weather is mostly sunny with light rain.

calendarCalendar MonthtemperatureTemperaturerainPrecipitationmostlyCloudinessoccupationOccupancypricePricing
January53.4°F (11.9°C)Light RainMostly SunnyAverageSlightly Low
February57.9°F (14.4°C)Light RainMostly SunnyAverageAverage
March62.8°F (17.1°C)Light RainMostly SunnyAverageSlightly High
April69.1°F (20.6°C)Light RainMostly SunnyAverageAverage
May75.4°F (24.1°C)Light RainMostly SunnyModerately LowSlightly High
June80.2°F (26.8°C)Light RainMostly SunnyModerately HighAverage
July81.5°F (27.5°C)Light RainMostly SunnyModerately HighAverage
August81.3°F (27.4°C)Light RainMostly SunnyModerately HighSlightly Low
September77.9°F (25.5°C)Light RainMostly SunnyAverageAverage
October70.9°F (21.6°C)No RainMostly SunnyAverageSlightly High
November61.7°F (16.5°C)Light RainMostly SunnyModerately LowSlightly Low
December57.4°F (14.1°C)Light RainMostly SunnyAverageAverage

The nearest major airports for your trip to O Brien

To visit O'Brien, Florida, you can fly into three major airports. Jacksonville International Airport (JAX) is 81 miles away, with nearby hotels like the 4-star DoubleTree by Hilton Hotel Jacksonville Airport, only 0.3 miles from the terminal. Tallahassee International Airport (TLH) is 87 miles away, offering hotel options such as the 4-star DoubleTree by Hilton Hotel Tallahassee, located 5 miles from the airport. Gainesville Regional Airport (GNV) is the closest at 47 miles, with accommodations including the 4-star DoubleTree by Hilton Gainesville, situated 8 miles away. Each airport provides various transportation services to these hotels for added convenience.

Why book with Expedia?

  • Flexible booking

    On Expedia, you can find plenty of hotels with flexible cancellation in O Brien using the “Fully refundable property” search filter. Just be sure to always double-check each hotel's cancellation policy before booking.

  • Book now and pay later

    With countless book now, pay later options, there's no need to wait till payday to grab a deal. Use the “Reserve now, pay later” search filter to view all properties available with this payment option in O Brien.

  • Hotel comparison

    Thanks to the handy “Compare properties” tool on Expedia, you can compare hotels in O Brien side by side with just a few clicks.

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Frequently asked questions

What is the best area to stay in O Brien?
The best area to stay in O'Brien, Florida, is near the I-10 and US-129 interchange, as this offers the most convenient access to local attractions and amenities.

This area, located directly at the intersection of the two major roadways, provides easy entry to O'Brien and the surrounding region. While O'Brien itself is a small, rural community, this hub offers the most centralized location for exploring the natural springs and outdoor activities North Florida is known for. You'll find the few local businesses and dining options clustered around this intersection.

For families, staying near this interchange is ideal because it minimizes travel time to popular destinations like the nearby natural springs. Many of these springs offer swimming, snorkeling, and canoeing, making them great for a day out with children. The convenience of quick access to the main roads means less time navigating and more time enjoying the outdoors.

Solo travelers also benefit from staying in this central location. It provides a practical base for exploring the area's natural beauty, such as kayaking on the Suwannee River or visiting local state parks.
When is the best time to go to O Brien?
The best time to visit O'Brien, Florida, is during the spring (March to May) and fall (September to November) for comfortable weather and pleasant outdoor activities.

During these seasons, O'Brien experiences mild temperatures, typically ranging from the low 70s to mid-80s Fahrenheit, with lower humidity than the summer months. This makes it ideal for enjoying the area's natural springs and outdoor recreation without the intense heat or the higher chance of thunderstorms characteristic of summer.

Travelers looking to explore the natural beauty of the area will find spring and fall particularly appealing. The cooler weather is great for swimming, kayaking, and tubing in the crystal-clear waters of the nearby Ichetucknee Springs State Park or the Suwannee River.
Can I cancel my hotel reservation on Expedia?
You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in O Brien.
How can I save on a O Brien hotel booking with Expedia?
With Expedia, you earn OneKeyCash™* on eligible O Brien hotel bookings for every dollar you spend – just join our One Key™ travel rewards program to get started. It's free to join, and you'll unlock our lowest Member Prices as soon as you're signed in. On top of this, you could also save significantly by bundling your hotel and flights together on Expedia.

*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia, Hotels.com and Vrbo.
How much is the nightly rate at a O Brien hotel?
Prices for hotels in O Brien often vary, but you can find a great deal from $43 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate.

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