Find hotels in Mayo, FL from $41

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Our top choices for Mayo hotels

Cindys Motel

Cindys Motel
2.5 star property
Mayo
8.8 out of 10, Excellent, (128)
"Nice place"
Australia
Marie
$91 nightly
The price is $98
Jan 7 - Jan 8, 2026
Total with taxes and fees
Cindys Motel

Suwannee River Rendezvous

Suwannee River Rendezvous
2.5 star property
Mayo
8.6 out of 10, Excellent, (19)
"Always a good time!"
United States
Madalaine
$38 nightly
The price is $41
Dec 25 - Dec 26
Total with taxes and fees
Suwannee River Rendezvous

Holiday Inn Express & Suites Live Oak by IHG

Holiday Inn Express & Suites Live Oak by IHG
2.5 star property
Live Oak
8.4 out of 10, Very Good, (775)
"Have stayed here whenever we are in town. Always god stay."
United States
Gregg
$121 nightly
The price is $133
Jan 11 - Jan 12, 2026
Total with taxes and fees
Holiday Inn Express & Suites Live Oak by IHG

Best Western Plus Madison

Best Western Plus Madison
2.5 star property
Madison
8.0 out of 10, Very Good, (574)
"Clean room, friendly staff, good breakfast."
United States
erik
$112 nightly
The price is $127
Jan 12 - Jan 13, 2026
Total with taxes and fees
Best Western Plus Madison

Putnam Lodge Hotel and Spa

Putnam Lodge Hotel and Spa
2.5 star property
Cross City
9.2 out of 10, Wonderful, (363)
"Historic! "
United States
William
$160 nightly
The price is $176
Jan 2 - Jan 3, 2026
Total with taxes and fees
Putnam Lodge Hotel and Spa

Econo Lodge Live Oak

Econo Lodge Live Oak
2.0 star property
Live Oak
7.0 out of 10, Good, (277)
"need grab bars"
United States
Frances and Edward
$65 nightly
The price is $72
Jan 23 - Jan 24, 2026
Total with taxes and fees
Econo Lodge Live Oak

Royal Inn Motel

Royal Inn Motel
2.0 star property
Perry
8.8 out of 10, Excellent, (988)
"Check in and check out was quick, convenient. It was a pleasure staying here. I will stay here again when in town."
United States
Darla
$79 nightly
The price is $88
Dec 28 - Dec 29
Total with taxes and fees
Royal Inn Motel

Quality Inn & Suites Live Oak I-10 Exit 283

Quality Inn & Suites Live Oak I-10 Exit 283
2.5 star property
Live Oak
7.0 out of 10, Good, (518)
"Staff was very friendly, check-in was super fast, decent room, neat and clean, comfy veds, big towels, breakfast was ok."
United States
Charlotte
$86 nightly
The price is $94
Dec 25 - Dec 26
Total with taxes and fees
Quality Inn & Suites Live Oak I-10 Exit 283

Days Inn by Wyndham Madison

Days Inn by Wyndham Madison
2.0 star property
Madison
7.0 out of 10, Good, (575)
"Room was clean. Everyone was very courteous!"
United States
Al
$74 nightly
The price is $84
Dec 29 - Dec 30
Total with taxes and fees
Days Inn by Wyndham Madison

Good Times Motel and Marina

Good Times Motel and Marina
2.0 star property
Steinhatchee
9.4 out of 10, Exceptional, (72)
"Fantastic stay! Beautiful cabin and Tiny was a great host. The restaurant was great too. Would love to go back."
United States
Josh
$89 nightly
The price is $98
Dec 31 - Jan 1, 2026
Total with taxes and fees
Good Times Motel and Marina

Super 8 by Wyndham Madison

Super 8 by Wyndham Madison
2.0 star property
Madison
7.4 out of 10, Good, (633)
"Nice place "
United States
James
$72 nightly
The price is $81
Dec 29 - Dec 30
Total with taxes and fees
Super 8 by Wyndham Madison

Steinhatchee River Inn

Steinhatchee River Inn
2.0 star property
Steinhatchee
9.4 out of 10, Exceptional, (385)
"Friendly staff and clean room"
United States
Pegg
$139 nightly
The price is $156
Dec 25 - Dec 26
Total with taxes and fees
Steinhatchee River Inn

Holiday Inn Express Hotel & Suites PERRY by IHG

Holiday Inn Express Hotel & Suites PERRY by IHG
2.5 star property
Perry
8.6 out of 10, Excellent, (705)
"Good staff "
United States
Emmett
$134 nightly
The price is $150
Jan 23 - Jan 24, 2026
Total with taxes and fees
Holiday Inn Express Hotel & Suites PERRY by IHG

Hampton Inn Perry

Hampton Inn Perry
2.5 star property
Perry
8.6 out of 10, Excellent, (723)
"Nice place to stay in a small town"
United States
Joyce
$122 nightly
The price is $137
Jan 19 - Jan 20, 2026
Total with taxes and fees
Hampton Inn Perry

Fiddler's Restaurant and Resort

Fiddler's Restaurant and Resort
2.0 star property
Steinhatchee
8.6 out of 10, Excellent, (287)
"great place"
United States
mike
$96 nightly
The price is $108
Dec 30 - Dec 31
Total with taxes and fees
Fiddler's Restaurant and Resort

Skylark Motel

Skylark Motel
2.5 star property
Perry
6.0 out of 10, (47)
"No wifi.... but very clean room. This is a very small motor-inn. It was great for a single night traveling through the area."
United States
Brian
$57 nightly
The price is $64
Jan 11 - Jan 12, 2026
Total with taxes and fees
Skylark Motel

Carriage Inn Motel

Carriage Inn Motel
2.0 star property
Cross City
5.6 out of 10, (128)
"I would sleep in my own car in a Loves truck stop before staying here again. "
United States
Heather
$110 nightly
The price is $121
Dec 25 - Dec 26
Total with taxes and fees
Carriage Inn Motel

Regency Inn

Regency Inn
2.5 star property
Perry
5.2 out of 10, (225)
"The front desk staff was wonderful. It was decent for a one night stay only."
United States
Dale
$91 nightly
The price is $102
Jan 6 - Jan 7, 2026
Total with taxes and fees
Regency Inn

Cross City Motel by Hotel O Hwy 98

Cross City Motel by Hotel O Hwy 98
2.5 star property
Cross City
3.8 out of 10, (6)
"Do not stay here! Dirty, disgusting place with live bugs to keep you company."
United States
Ryan
$65 nightly
The price is $72
Dec 25 - Dec 26
Total with taxes and fees
Cross City Motel by Hotel O Hwy 98
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Stay near popular Mayo attractions

Learn more about Mayo

Paddle through crystal-clear waters at Lafayette Blue Springs State Park where swimming and snorkeling reveal underwater caves and limestone formations. Explore the peaceful Suwannee River by kayak or visit Perry Spring, where locals gather for refreshing dips during hot summer afternoons.

kayakers at Rock Bluff Spring on the Suwanneee River, Gilchrist County, Florida

Top Mayo Hotel Reviews

More cheap stays in Mayo

Hotels in Mayo with star-rating

Find out more about Mayo

Top reasons to visit Mayo

  • Outdoor Adventure: Mayo is a haven for outdoor enthusiasts, offering activities like hiking, fishing, and birdwatching in its stunning natural surroundings.
  • Scenic Rivers: Explore the beautiful Suwannee River, perfect for kayaking and relaxing by the water.
  • State Parks: Nearby state parks provide additional opportunities for adventure and exploration amidst lush landscapes.
  • Charming Downtown: Enjoy the welcoming atmosphere of Mayo's downtown area, filled with local shops and eateries.
  • Comfortable Accommodations: A variety of cozy, pet-friendly hotels ensure a comfortable stay for every traveler.

Find great hotels near Mayo

Discover the perfect getaway in Mayo, Florida, where a variety of hotel accommodations await to cater to your every need. From cozy motels to inviting hotels, you'll find options that are pet-friendly and ideal for business travelers or adventure seekers. With a focus on quality service and comfort, Mayo's hotels promise a memorable stay. Explore top-rated hotels, read reviews, and enjoy a delightful experience in this charming destination.

  • Holiday Inn Express Hotel & Suites LIVE OAK by IHG: Located 23 miles from Mayo, this hotel is perfect for business travelers seeking a welcoming environment. Recognized by LGBTQIA travel guides, it embodies inclusivity and comfort. The hotel features a well-equipped Business Center and a Meeting Room, facilitating productive stays. Guests can enjoy modern amenities and a complimentary breakfast, ensuring a refreshing start to each day. With its focus on business needs and a friendly atmosphere, this hotel is an excellent choice for those on the go.
  • Royal Inn Motel: Situated 25 miles from Mayo, the Royal Inn Motel offers a classic and straightforward lodging experience. Ideal for travelers looking for convenience and comfort, the motel provides entertainment options including Cable TV and LCD TV in every room. The relaxed ambiance and essential amenities create a cozy retreat after a day of exploration. Whether you're in town for business or leisure, Royal Inn Motel makes for an affordable and enjoyable stay.
  • Quality Inn & Suites Live Oak I-10 Exit 283: Located 22 miles from Mayo, this hotel caters to both business travelers and pet owners. With a Business Center available for professional needs, guests can balance work and leisure seamlessly. The property is pet-friendly, allowing pets with certain restrictions, making it ideal for those traveling with furry companions. Quality Inn & Suites ensures a comfortable stay with thoughtful amenities and a welcoming atmosphere, perfect for a memorable visit.

Where to stay in and around Mayo

Mayo, Florida, is an outdoor enthusiast's paradise, offering stunning scenery and thrilling adventures. Explore nearby natural wonders like the scenic Suwannee River and the lush forests of the Big Bend region. Enjoy activities such as hiking, fishing, and birdwatching, all within walking distance of the charming downtown area. With its inviting atmosphere and proximity to beautiful beaches, Mayo promises an unforgettable vacation experience for nature lovers and adventure seekers alike.

  • O Brien: A charming city located 14 miles from Mayo, O Brien offers a delightful blend of outdoor adventures and stunning scenery. Known for its seasonal influx of visitors, particularly from June to August, this area is perfect for those seeking adventure. Engage in a variety of activities like underwater sports and recreational outings. O Brien is also home to beautiful rivers, a national state park, and captivating water features, making it an ideal spot for nature enthusiasts and thrill-seekers alike.
  • Day: Nestled within the Mayo area, Day is a quaint village that provides a serene escape for travelers. While visitor numbers peak in March and during the summer months of June to July, this locale offers a consistent allure throughout the year. Day is best known for its scenic beaches and recreational areas, making it a fantastic destination for outdoor fun with family. Explore nearby attractions like family-friendly beaches and rivers, perfect for a day of relaxation or adventure.
  • Dowling Park: Just 14 miles from Mayo, Dowling Park is a picturesque village that thrives on the beauty of nature and outdoor activities. With peak visitor months in April, July, and September, this area is a haven for those looking for adventure. Visitors can enjoy hiking trails, campgrounds, and recreational areas surrounded by breathtaking landscapes. The proximity to rivers and national state parks adds to its charm, making Dowling Park a must-visit for nature lovers and outdoor enthusiasts.

Things to do near Mayo

Mayo, Florida, is perfect for outdoor enthusiasts seeking adventure and stunning scenery. Visitors can enjoy recreational areas, partake in exciting adventure activities, and explore underwater sports. Additionally, the area offers beautiful golf views, making it an ideal destination for both relaxation and thrill-seeking. Whether you're looking to unwind in nature or engage in active pursuits, Mayo has something for everyone.

Shopping

Mayo, Florida offers charming local shops perfect for finding unique gifts and souvenirs. Check out the quaint boutiques downtown for handmade items. If you're up for a drive, head to nearby Live Oak, where you can explore larger shopping centers like the Live Oak Plaza for more options.

Recreation

At Spirit of the Suwannee Music Park, immerse yourself in nature with tranquil walking trails and cozy campfires. Taylor County Sports Complex offers recreational facilities for outdoor activities, while William Guy Lemmon Memorial Park invites relaxation among scenic landscapes, perfect for unwinding and enjoying fresh air.

Adventure

At Bob's River Place, 23 miles from Mayo, enjoy thrilling water sports amidst a lively atmosphere. Yogi Bear's Jellystone Park, 26 miles away, offers family-friendly camping adventures surrounded by nature. For more outdoor excitement, head to Steinhatchee Public Boat Ramp, located 29 miles from Mayo, for exhilarating water activities.

Nightlife

Experience the laid-back nightlife in Mayo at the Suwannee River Saloon, where you can enjoy live music and dance the night away. For a cozy atmosphere, visit the local café for drinks and mingling with friendly locals, creating a memorable evening under the stars.

*Distances are measured in a straight line; actual driving distances may vary depending on the route.

Booking tips and Expedia advantages for Mayo

To save money on your trip to Mayo, Florida, consider visiting between December and February for the lowest prices. Book your stay on a Monday for better rates, avoiding the more expensive Friday. Use Expedia’s search tool to find affordable accommodations, filter for eco-friendly hotels, and take advantage of package deals that combine flights and activities. Joining Expedia’s One Key membership can provide exclusive discounts and opportunities to earn OneKeyCash for future stays. Don't forget to explore free activities in the area to maximize your savings.

  • The most and least expensive months on average to stay in a hotel: The cheapest months to stay in Mayo are December to February, where the prices are slightly lower. This is in comparison to June to July and October, where prices are slightly higher.
  • The most and least expensive days on average to stay in a hotel: The least expensive day to stay in Mayo is Monday. The most expensive day to stay in Mayo is Friday.
  • Find cheap hotels on Expedia: Expedia’s search tool makes it easy to choose your budget, desired location, and additional preferences. You can arrange your results to display prices from lowest to highest, ensuring you spot the most affordable hotels right away. Additionally, you have the option to refine your search by hotel type. For instance, if you select the Eco-certified filter, you'll find a selection of sustainable and environmentally friendly hotels available for booking.
  • Consider bundling your trip: You can save money by combining your hotel stay in Mayo with your flights and activities through an Expedia package deal.
  • Become a One Key member: Join Expedia's One Key membership program for exclusive discounts and deals on hotel bookings. You can also earn OneKeyCash to use on future selected hotels.

Find the best attractions in and around Mayo

Mayo, Florida, is perfect for outdoor enthusiasts and adventure seekers, offering a variety of scenic attractions. Visitors can explore beautiful rivers, enjoy the natural wonders of nearby state parks, and discover local libraries. These points of interest provide a family-friendly experience, making Mayo an ideal destination for creating lasting memories in nature.

  • Lafayette Blue Springs State Park: Experience the stunning natural beauty of Lafayette Blue Springs State Park, where adventure awaits with crystal-clear springs ideal for swimming and kayaking. Enjoy scenic hiking trails and abundant wildlife in this serene outdoor oasis.
  • Suwannee River: Just 16 miles from Mayo, the Suwannee River offers breathtaking views and a tranquil atmosphere perfect for canoeing or picnicking along its banks. Immerse yourself in nature as you explore its winding paths and lush surroundings.
  • Baker Park: Located 18 miles from Mayo, Baker Park is a family-friendly urban park featuring playgrounds, picnic areas, and walking trails. Enjoy outdoor activities while surrounded by the vibrant energy of the city, making it a great spot for relaxation and fun.

Best time to go to Mayo

The best time to visit Mayo can depend on the weather and when visitor numbers rise and fall. The hottest average temperature in Mayo falls in July, when visitor numbers are average and weather is mostly sunny with light rain. The coolest average temperature in Mayo falls in January, visitor numbers are average and weather is mostly sunny with light rain.

calendarCalendar MonthtemperatureTemperaturerainPrecipitationmostlyCloudinessoccupationOccupancypricePricing
January53.4°F (11.9°C)Light RainMostly SunnyAverageSlightly Low
February57.9°F (14.4°C)Light RainMostly SunnySlightly LowSlightly Low
March62.8°F (17.1°C)Light RainMostly SunnySlightly HighAverage
April69.1°F (20.6°C)Light RainMostly SunnySlightly HighAverage
May75.4°F (24.1°C)Light RainMostly SunnyAverageAverage
June80.2°F (26.8°C)Light RainMostly SunnyAverageSlightly High
July81.5°F (27.5°C)Light RainMostly SunnyAverageSlightly High
August81.3°F (27.4°C)Light RainMostly SunnySlightly LowAverage
September77.9°F (25.5°C)Light RainMostly SunnySlightly HighAverage
October70.9°F (21.6°C)No RainMostly SunnyAverageSlightly High
November61.9°F (16.6°C)Light RainMostly SunnyAverageAverage
December57.4°F (14.1°C)Light RainMostly SunnySlightly LowSlightly Low

The nearest major airports for your trip to Mayo

Traveling to Mayo, Florida, can be conveniently done by flying into two major airports. Gainesville Regional Airport (GNV) is located 59 miles away, with hotel options such as the 4-star DoubleTree by Hilton Gainesville, just 8 miles from the airport, and Hotel Eleo at the University of Florida, a 3.5-star hotel 5 miles away. Alternatively, Valdosta Regional Airport (VLD) is 51 miles away from Mayo, offering nearby accommodations like the 3-star Drury Plaza Hotel Valdosta and Hilton Garden Inn Valdosta, both situated 5 miles from the airport. Each hotel provides access to transportation services for a smooth journey to Mayo.

Frequently asked questions

What is the best area to stay in Mayo?
The best area to stay in Mayo, Florida, is in the heart of downtown Mayo, particularly around Main Street (US-27).

This central area is the hub of local activity, featuring Mayo's few local businesses, dining options, and access to services. It's a small, walkable area centered around the intersection of Main Street and Lafayette Street, making it easy to access everything the town offers.

For solo travelers or couples seeking a quiet, authentic small-town experience, staying downtown provides convenient access to local eateries and shops.
What are the best hotels in Mayo that travelers recommend?
Two of the best hotels in Mayo that travelers recommend are Suwannee River Rendezvous and Cindys Motel.

Suwannee River Rendezvous, with an 8.6 rating, is a great option for guests seeking a resort experience with extensive pool facilities including sun loungers and an outdoor pool. Many guests appreciate the beautiful scenery and the kind staff, and it is conveniently located just 13.2 miles from the Suwannee River.

Another highly recommended choice is Cindys Motel, which boasts an impressive 9.0 rating. This motel offers practical amenities such as air conditioning, free self-parking, and complimentary RV, bus, and truck parking. Guests consistently praise the clean and great rooms, and it is very close to local attractions, being only 0.1 miles from Veteran's Memorial Park of Mayo and 0.4 miles from Lafayette County Library.
What are the best family hotels in Mayo?
For a family-friendly hotel in Mayo, consider the Suwannee River Rendezvous.

This hotel, with an 8.6 rating, is much-loved by families and offers a variety of pool options, including an outdoor pool and a shared, secured pool area. Connecting rooms are available, as are kid's meals, making it convenient for families. Guests frequently mention the beautiful scenery and kind staff. It is located 13.2 miles from the Suwannee River.
What are the top pet-friendly hotels in Mayo?
For pet-friendly hotels in Mayo, consider Cindys Motel or Suwannee River Rendezvous.

Cindys Motel, with a 9.0 rating, is an excellent choice for travelers with dogs, as it specifically permits dogs and offers complimentary WiFi. Guests frequently mention the clean rooms, and the hotel provides free self-parking as well as free parking for RVs, buses, and trucks. It is conveniently located near Veteran's Memorial Park of Mayo, just 0.1 miles away, and the Lafayette County Library, which is 0.4 miles away.

Another highly-rated option is Suwannee River Rendezvous, with an 8.6 rating. This hotel welcomes pets and features a dedicated dog exercise area, making it ideal for pet owners. Guests appreciate the beautiful scenery and kind staff. The property also boasts an outdoor pool with sun loungers, offering a pleasant relaxation spot. It is located 13.2 miles from the Suwannee River. See more pet-friendly hotels in Mayo
What are the best budget hotels in Mayo?
For budget-friendly accommodations in Mayo, consider Cindys Motel or Suwannee River Rendezvous.

Cindys Motel, with a 9.0 rating, offers convenient amenities such as free WiFi and complimentary self-parking, including space for RVs, buses, and trucks. Guests often describe the rooms as clean and great. It is also very close to Veteran's Memorial Park of Mayo, just 0.1 miles away.

Another good option is Suwannee River Rendezvous, rated 8.6. This hotel provides free self-parking, free WiFi, and a selection of pool amenities including an outdoor pool with sun loungers. Travelers frequently mention the beautiful scenery and kind staff. It is located about 13.2 miles from the Suwannee River. View all budget hotels in Mayo
What are the most romantic hotels in Mayo for couples?
For couples seeking a romantic getaway in Mayo, the Suwannee River Rendezvous is an excellent choice.

This highly-rated accommodation, with an 8.6 review score, offers a serene setting great for couples. Guests frequently praise the beautiful scenery and the kind staff, ensuring a pleasant stay. The property features an outdoor pool with sun loungers, providing a relaxing spot to unwind together. Additionally, it is conveniently located just 13.2 miles from the Suwannee River, offering opportunities for scenic strolls or other romantic activities.
What are the best hotels in Mayo near Suwannee River?
For hotels in Mayo near the Suwannee River, Suwannee River Rendezvous is a good option.

Suwannee River Rendezvous, with an 8.6 rating, is located approximately 13.2 miles from the Suwannee River. This hotel offers a variety of pool options, including an outdoor pool, and features connecting rooms, which can be convenient for families. Guests often mention the beautiful scenery.
When is the best time to go to Mayo?
The best time to go to Mayo, Florida, is during the spring and fall months, specifically from March to May and September to November. These periods offer the most pleasant weather conditions for exploring the area.

During spring, you'll find comfortable temperatures, typically ranging from the low 70s to high 80s Fahrenheit, with lower humidity. This makes it ideal for outdoor activities like visiting local springs or exploring the nearby Suwannee River. It's a great time for travelers who enjoy hiking, kayaking, or simply relaxing outdoors without the intense summer heat.

Fall also provides agreeable weather, with temperatures mirroring those of spring and generally less rainfall than the summer. This season is superb for couples or solo travelers looking for a tranquil getaway, as the cooler air is conducive to enjoying nature trails and local events without large crowds.
Can I cancel my hotel reservation on Expedia?
You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Mayo.
How can I save on a Mayo hotel booking with Expedia?
With Expedia, you earn OneKeyCash™* on eligible Mayo hotel bookings for every dollar you spend – just join our One Key™ travel rewards program to get started. It's free to join, and you'll unlock our lowest Member Prices as soon as you're signed in. On top of this, you could also save significantly by bundling your hotel and flights together on Expedia.

*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia, Hotels.com and Vrbo.
How much is the nightly rate at a Mayo hotel?
Prices for hotels in Mayo often vary, but you can find a great deal from $41 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate.

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