Guatemala Luxury Vacations

Book a Luxury Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to $2,000 when you book a flight and hotel together*
  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package
  • Rest easy

    Plan, book, and manage your trip all in one place

Top Luxury vacation packages in Guatemala

Price found within the past 48 hours. Click for updated prices.
Los Pasos Boutique Hotel & Spa

Los Pasos Boutique Hotel & Spa

$924
per person
Nov 8 - Nov 12
found 1 day ago
Roundtrip non-stop flight included
Pittsburgh (PIT) to Guatemala City (GUA)
9.4/10 Exceptional! (1,007 reviews)
Ame la atención! 100% recomendado, volveré!!

Reviewed on Aug 31, 2026

Hotel Museo Spa Casa Santo Domingo

Hotel Museo Spa Casa Santo Domingo

Barrio de La Concepción
$1,126
per person
Nov 8 - Nov 12
found 1 day ago
Roundtrip non-stop flight included
Pittsburgh (PIT) to Guatemala City (GUA)
9.4/10 Exceptional! (1,125 reviews)
I cant believe they do not sell Coca-Cola. They have some king if deal with Pepsi and Pepsi is not OK. Otherwise the food is good, but nothing goes better with a burger than a Coke.

Reviewed on Sep 8, 2026

El Convento Boutique Hotel

El Convento Boutique Hotel

Historic Center
$1,275
per person
Nov 26 - Nov 29
found 15 hours ago
Roundtrip non-stop flight included
New York (NYC) to Guatemala City (GUA)
9.4/10 Exceptional! (923 reviews)
InterContinental Real Guatemala by IHG

InterContinental Real Guatemala by IHG

Zona 10
$1,275
per person
Nov 8 - Nov 12
found 8 hours ago
Roundtrip non-stop flight included
Miami (MIA) to Guatemala City (GUA)
9.2/10 Wonderful! (1,010 reviews)
Porta Hotel Antigua

Porta Hotel Antigua

$1,020
per person
Nov 19 - Nov 22
found 1 day ago
Roundtrip non-stop flight included
New York (NYC) to Guatemala City (GUA)
9.4/10 Exceptional! (1,004 reviews)
El lugar y la comida

Reviewed on Sep 8, 2026

Don't see what you're looking for?
See all available trips from Columbus to Guatemala
View all trips

5* Luxury vacations in Guatemala

Price found within the past 48 hours. Click for updated prices.
InterContinental Real Guatemala by IHG

InterContinental Real Guatemala by IHG

Zona 10
$1,275
per person
Nov 8 - Nov 12
found 8 hours ago
Roundtrip non-stop flight included
Miami (MIA) to Guatemala City (GUA)
9.2/10 Wonderful! (1,010 reviews)
Don't see what you're looking for?
See all available trips from Columbus to Guatemala
View all trips

3 Night Luxury vacations in Guatemala

Price found within the past 48 hours. Click for updated prices.
Hotel Camino Real Antigua

Hotel Camino Real Antigua

Historic Center
$826
per person
Nov 17 - Nov 20
found 15 hours ago
Roundtrip non-stop flight included
Miami (MIA) to Guatemala City (GUA)
9.6/10 Exceptional! (1,005 reviews)
Hermoso!

Reviewed on Sep 8, 2026

Hotel Museo Spa Casa Santo Domingo

Hotel Museo Spa Casa Santo Domingo

Barrio de La Concepción
$992
per person
Nov 30 - Dec 3
found 1 day ago
Roundtrip flight included
Dallas (DFW) to Guatemala City (GUA)
9.4/10 Exceptional! (1,125 reviews)
I cant believe they do not sell Coca-Cola. They have some king if deal with Pepsi and Pepsi is not OK. Otherwise the food is good, but nothing goes better with a burger than a Coke.

Reviewed on Sep 8, 2026

El Convento Boutique Hotel

El Convento Boutique Hotel

Historic Center
$1,275
per person
Nov 26 - Nov 29
found 15 hours ago
Roundtrip non-stop flight included
New York (NYC) to Guatemala City (GUA)
9.4/10 Exceptional! (923 reviews)
Don't see what you're looking for?
See all available trips from Columbus to Guatemala
View all trips

4 Night Luxury vacations in Guatemala

Price found within the past 48 hours. Click for updated prices.
Hotel Casa Antigua by AHS

Hotel Casa Antigua by AHS

Historic Center
$679
per person
Nov 8 - Nov 12
found 1 day ago
Roundtrip non-stop flight included
Pittsburgh (PIT) to Guatemala City (GUA)
8.2/10 Very Good! (645 reviews)
Hotel Museo Spa Casa Santo Domingo

Hotel Museo Spa Casa Santo Domingo

Barrio de La Concepción
$1,126
per person
Nov 8 - Nov 12
found 1 day ago
Roundtrip non-stop flight included
Pittsburgh (PIT) to Guatemala City (GUA)
9.4/10 Exceptional! (1,125 reviews)
I cant believe they do not sell Coca-Cola. They have some king if deal with Pepsi and Pepsi is not OK. Otherwise the food is good, but nothing goes better with a burger than a Coke.

Reviewed on Sep 8, 2026

Los Pasos Boutique Hotel & Spa

Los Pasos Boutique Hotel & Spa

$924
per person
Nov 8 - Nov 12
found 1 day ago
Roundtrip non-stop flight included
Pittsburgh (PIT) to Guatemala City (GUA)
9.4/10 Exceptional! (1,007 reviews)
Ame la atención! 100% recomendado, volveré!!

Reviewed on Aug 31, 2026

Don't see what you're looking for?
See all available trips from Columbus to Guatemala
View all trips

All you need to know about luxury vacations in Guatemala

What can I expect from a luxury Guatemala vacation?

Luxury means the very finest of the things you enjoy most. Indulge your every waking moment—and restful night—with a luxury Guatemala vacation. Sip handcrafted cocktails by an infinity pool, sink into bliss at a full-service spa with a massage cabana on the beach, and chat, cheers, and laugh through exquisite breakfasts, lunches, and dinners with spectacular views. 

How can I find all-inclusive luxury vacation packages in Guatemala?

By refining your filters, the most opulent all-inclusive vacation packages will appear before your eyes. Check the 5* filter to find truly sensational stays. You barely need to lift a finger. 

Can I book a cheap Guatemala luxury vacation?

Affordable luxury is only ever a few clicks away. Enter your travel dates and sort the grandiose getaways on offer by price to see the most fiscally friendly retreats first. Filter by budget, too, to find your perfect balance of luxury. Right now, luxury vacations start at $679. Prices and availability are subject to change. Additional terms may apply.

How can I book a luxury family vacation in Guatemala?

Tailor your luxury family escape by checking the filters that set the whole family’s hearts a-flutter. Whether that’s wet and wild water parks, heavenly hot tubs, or the kid-quieting magic of free Wi-Fi. 

Can I book a package in Guatemala with a luxury vacation home?

A private paradise is true luxury! Filter by property type for houses, villas, and apartments. For an amazingly affordable all-in-one luxury experience, book your accommodation, airfare, and car rental as a package.   

How can I find the best luxury vacation deals in Guatemala?

Find absolute delight in the dropdown! Simply sort your tempting search results by deals to find that lean-budget luxury. For a budget conscious stay, consider booking a stay away from big cities or outside the peak months.

Can I book a luxury holiday in Guatemala with free cancellation and/or flexible dates?

Freedom and flexibility are the greatest luxuries of all. Get both when you filter by payment option and book a trip with free cancellation or on a buy now, pay later plan. 

Why should I book my luxury trip to Guatemala with Expedia?

A luxurious trip follows a stress-free booking experience. Find, build, and book the most glorious of getaways in seconds—with ATOL protection for added peace of mind.

Top Luxury Guatemala Hotels

Barceló Guatemala City

Barceló Guatemala City

7 Avenida 15-45, Zona 9 Guatemala City Guatemala
  • 57 min drive from Lake Atitlán
$95 nightly
$116 total
Sep 13 - Sep 14
Total with taxes and fees
Visit Barceló Guatemala City for a relaxing stay in Guatemala City. Popular amenities include a spa, 2 bars, and an outdoor pool.
Barceló Guatemala City
Hilton Guatemala City

Hilton Guatemala City

Km. 9.5 CA 1 East Santa Catarina Pinula Guatemala
  • 1 hour drive from Lake Atitlán
$109 nightly
$134 total
Sep 12 - Sep 13
Total with taxes and fees
Hilton Guatemala City is one of the Santa Catarina Pinula luxury 4.5-star boutique properties where you can pamper yourself with massage services, 24-hour room ...
Hilton Guatemala City
The Westin Camino Real, Guatemala

The Westin Camino Real, Guatemala

Calle Camino Real 0-20, Zona 10 Guatemala City Guatemala
  • 58 min drive from Lake Atitlán
$130 nightly
$158 total
Sep 19 - Sep 20
Total with taxes and fees
Be treated to a luxury stay at The Westin Camino Real, Guatemala, where you can enjoy amenities like massage services, 24-hour room service, and more. Notable ...
The Westin Camino Real, Guatemala
See all 2,418 properties in Guatemala
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

More vacations you might like

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.