Santa Croce Vacations from $1,582

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Your Santa Croce Vacation

Discover the best that Santa Croce offers with a Santa Croce vacation package. From its culture to every other thing that makes it special, this neighborhood will charm you from beginning to end. When it's time to take in the sights, you'll find loads of popular attractions nearby including Rialto Bridge, St. Marks Basilica and St. Marks Square. Visit one, two or more during your trip to Santa Croce. Don't just dream it — do it! Lock in your ideal Santa Croce vacation with Expedia and experience travel your way.

The Latest Santa Croce Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Hotel Bisanzio

Hotel Bisanzio

4 out of 5
Castello
Price was $2,321, price is now $1,582 per person
$1,582
per person
Jun 5 - Jun 10
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to Venice (VCE)
9/10 Wonderful! (1,003 reviews)
Lovely staff and absolute cute bedroom with a balcony. Clean but would need a renovation.

Reviewed on Apr 11, 2026

Ca' Sagredo

Ca' Sagredo

5 out of 5
Venice City Center
Save 100% on your flight
Price was $4,085, price is now $2,762 per person
$2,762
per person
May 16 - May 22
found 12 hours ago
Roundtrip non-stop flight included
New York (JFK) to Venice (VCE)
9.2/10 Wonderful! (485 reviews)
Room was very clean and our terrace was wonderful. The staff was very friendly and accommodating.

Reviewed on Apr 5, 2026

Hotel Ca Marinella

Hotel Ca Marinella

3 out of 5
Castello
Price was $2,637, price is now $1,852 per person
$1,852
per person
May 16 - May 22
found 12 hours ago
Roundtrip non-stop flight included
New York (JFK) to Venice (VCE)
8.6/10 Excellent! (322 reviews)
Good location, good staff, clean

Reviewed on Feb 13, 2026

Cà Bonfadini Historic Experience

Cà Bonfadini Historic Experience

5 out of 5
Cannaregio
Price was $2,265, price is now $1,604 per person
$1,604
per person
Jul 4 - Jul 7
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to Venice (VCE)
9.8/10 Exceptional! (215 reviews)
Fantastic stay here. The staff were super friendly and attentive. Breakfast was decent with cooked to order options. The hotel is about 20mins walk to St Marc’s square.

Reviewed on Mar 27, 2026

Hotel Palazzetto Madonna

Hotel Palazzetto Madonna

4 out of 5
San Polo
Price was $2,877, price is now $2,040 per person
$2,040
per person
Jun 5 - Jun 10
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to Venice (VCE)
9.2/10 Wonderful! (1,001 reviews)
Breakfast was very good! Great selection. Very clean.

Reviewed on Apr 3, 2026

Where to stay in Santa Croce

Find the best Santa Croce areas and neighborhoods for the activities you enjoy most. Learn more about Santa Croce
Venice City Center

Venice City Center

4 out of top 10 points of interest in this area

Discover an abundance of architectural monuments and great art by grandmasters in the heart of an Italian city built on water.

Find hotels in Venice City Center

Santa Croce Hotel Deals

Palazzo Marcello Hotel al Sole

Palazzo Marcello Hotel al Sole

3 out of 5
Santa Croce 134/136 Venice VE
Fully refundableReserve now, pay when you stay
$199 nightly
The price is $228 total per night from Apr 19 to Apr 20
$228 total
Apr 19 - Apr 20
Total with taxes and fees
8.6/10 Excellent! (845 reviews)
Good service and convenient location

Reviewed on Mar 22, 2026

Palazzo Marcello Hotel al Sole
Hotel Antiche Figure

Hotel Antiche Figure

3 out of 5
Santa Croce 687 Venice VE
Fully refundableReserve now, pay when you stay
$229 nightly
The price is $260 total per night from Apr 15 to Apr 16
$260 total
Apr 15 - Apr 16
Total with taxes and fees
9.8/10 Exceptional! (1,004 reviews)
I booked this hotel based on the reviews, and am so glad I did. The location is the most convenient in Venice, only steps away from both the bus and train stations, which is a godsend, as anyone who's walked around Venice with luggage surely knows. The staff is excellent, they are always friendly ...

Reviewed on Apr 9, 2026

Hotel Antiche Figure
Hotel Canal Grande

Hotel Canal Grande

4 out of 5
Santa Croce 932 Venice VE
Fully refundableReserve now, pay when you stay
$228 nightly
The price is $261 total per night from Apr 27 to Apr 28
$261 total
Apr 27 - Apr 28
Total with taxes and fees
9.6/10 Exceptional! (1,001 reviews)
All very good, staffers are very nice, only thing need to improve is to provid anti-skip mat for the bathtub/shower for guest safty. The tub is pretty slippery.

Reviewed on Apr 6, 2026

Hotel Canal Grande
See all 6,235 properties in Santa Croce
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Vacations
All Inclusive Vacations
Beach Vacations
Beach Vacations
Kid Friendly Vacations
Kid Friendly Vacations

Discover the most popular places to visit in Santa Croce

moderne Fußgängerbrücke über den Canal Grande Venedig

Piazzale Roma

4.5/5(634 reviews)

You can learn about the local history of Venice during your trip to a top site like Piazzale Roma. Stroll along the marina or visit the stunning cathedral in the area.

Piazzale Roma
Fondaco dei Turchi am Canal Grande in Venedig, Italien

Fondaco dei Turchi

5/5(4 reviews)

You can browse the exhibits at Fondaco dei Turchi, a museum with a storied past, during your trip to Venice. Stroll along the marina or visit the churches in the area.

Fondaco dei Turchi
Venedig / Ca’ Pesaro

Ca'Pesaro

You can browse the exhibits at Ca'Pesaro, a museum with a storied past, during your trip to Venice. Stroll along the marina or visit the stunning cathedral in the area.

Ca'Pesaro

Things to do

Venice in a Day with St. Mark's Basilica, Doge's Palace, & Gondola Ride

Venice in a Day:Gondola Ride, Doge's Palace, St Mark's Basilica & City Tour

$169
per adult
94% of travellers recommend
Venice in a Day:Gondola Ride, Doge's Palace, St Mark's Basilica & City Tour
Tour of The Real Hidden Venice

Tour of The Real Hidden Venice

$68
per adult
92% of travellers recommend
Tour of The Real Hidden Venice
Venice: Basilica, Doge's Palace, Gondola Ride & History Gallery

Venice: Basilica, Doge's Palace, Gondola Ride & History Gallery

$152
per adult
Venice: Basilica, Doge's Palace, Gondola Ride & History Gallery
See all activities in Venice
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.